Depression treatment with natural acetyl l carnitine?
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- Опубликовано: 24 май 2024
- Let me know if there's a topic you would like to have me discuss 🙋🏻
✉️ askapsychiatrist.info/questions
Quite a few clinical studies have found that acetyl l carnitine can improve mood and energy.
Acetyl l carnitine has been compared to placebo treatments. It's also been compared to standard antidepressants. Most of those studies lead to the conclusion that acetyl l carnitine works like an antidepressant -- at least for older adults.
One of the limitations of the existing data is that most of the studies have been done on people over 50 years old. Whether it can work equally well for younger people is a question that's not been really well-addressed in the studies done up to this point.
One point I make in this lecture is that even natural products can have risks. There have been reports of acetyl l carnitine causing mania or psychosis in people with bipolar disorder.
As always, these lectures are for informational purposes only.
As always, seek the advice of your personal health care provider before making decisions to take medications or supplements.
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00:00 - Introducing a potential natural antidepressant option
00:38 - Why alternative antidepressant options are important
01:02 - Standard antidepressants often don’t work
01:17 - Side effects can create problems
01:42 - Standard antidepressants tend to have similar mechanisms of action
02:17 - Ideally, we could have antidepressants that work differently
02:38 - Many people prefer to avoid pharmaceutical treatments
03:07 - What is acetyl l carnitine?
04:42 - Structure and functions of acetylcarnitine
07:12 - Acetylcarnitine assists with energy metabolism
08:09 - Acetylcarnitine might boost neurotransmitter production
08:52 - Acetylcarnitine was studied as a treatment for Alzheimer’s disease
09:55 - Studies found that acetylcarnitine improves mood and boost energy
10:19 - Clinical studies of acetylcarnitine for depression treatment
11:19 - Acetylcarnitine appears to be effective for depression
11:50 - Limitations of the clinical studies
12:05 - Side effects of acetylcarnitine are generally small
13:13 - Even natural products have risk though
13:20 - Acetylcarnitine might cause mania or psychosis in people with bipolar disorder
14:54 - Acetylcarnitine levels in the blood are low in depression
16:07 - Why haven’t more people heard about acetylcarnitine for depression?
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This has been working very well for me. It’s a miracle. My energy levels are back.
My chronic fatigue in ADHD is caused by mitochondrial dysfunction and acetyl-L-carnitine has reduce that. I wish more videos like your were out there
If I do not take my Acetyl L Carnitine my depression comes back within a day. I tried Fluoxetine and other SSRI and they did LESS than nothing. Then one day about a year ago I took Acetyl L Carnitine and I actually laughed out loud to my self about some random thing, (a true laugh) something I had not done since I was a young teen. It works miracles for me, I don't know why it works or how. I only know that it works for me.
That's funny, I had the exact same response. I took it on whim as a preworkout and didn't expect anything. Strangely enough, after about 15 minutes, I was thinking about something and just had a good laugh. Also something I haven't experienced in a long time. I only took about 300 mg and it was my first dose ever so idk if it was just a placebo effect or not. I guess I'll know in a couple of weeks. I mean, it definitely had some type of effect or I would not be researching videos and posting randomly in chat about it.
@@dontump2286 yeah I been taking 1500 mg of acetyl l-carnitine in the morning every day. I can for sure tell a difference in my mood if I forget to take it. If it's working for real or a placebo I'm happy either way.
@@dontump2286 Any updates?
@@profbfc Good Question. Well first of all, I still have the "nearly" full bottle sitting here in my office. I don't think I took it more than a couple of days. Not so much because it wasn't good or was bad, but more so because I just got busy with other things and havent thought about it. I will say though, on days where I'm feeling sluggish or a little dumpy, I always glance over at the bottle and say to myself "should i take one." I guess it's hard to explain but there are no updates worth noting because I just never really took it long term.
I have no idea why it works either. I picked it up on a whim. Nothing happened really when I first took it, so I felt disappointed and put it into the stack of "failed" supplements. Then the next day I felt absolutely incredible. It was like I was young again.
It seems to have a slightly delayed response.
Great video! Perhaps you could discuss the other uses of ALC in another video and some safe dosages?
Fantastic video … would love to have videos on the most popular nootropics out there, especially: Citicholine (CDP-Choline), L-theanine, mucuna pruriens and others
Dear Dr. Messamore, Thank you so much for speaking the truth. I was beginning to think that a member of The Establishment wasn't allowed to do that. God Bless You.
One study has reported a narrowing of the carotid arteries of individuals with metabolic syndrome
Fantastic information here! I have bipolar 2 and struggle with depressive/ manic episodes. The medications always did more harm than good and after coming off of them i struggled with depressive episode that lasted over a year. I started taking acetyl-l-carnitine because i found that any vitamin/mineral that improved mitochondrial function would make me feel much better. I not only run a vitamin/nutrition store but also run experiments like these on myself in hopes to find a treatment that works for me. I have been taking the ALC for a several weeks and could instantly see improvements in my depression. I have been putting together information on diet, exercise, and supplements on myself for several years. And if you ever decide you would like to out together a study, i would love to help! There are solutions outside of pharmaceuticals, that i can say having tried both, are much more effective.
I would like help with alcar for depression. Just starting taking 3gms in am after 2 wks ln 2gms. Very impressed with your studies.
Interesting that ALC level is lower on those with depression.
Brilliant explanation of this, thankyou.
Outstanding presentation, Bravo. Thank you.
By the way it can cause hypothyroid symptoms in some ppl. It happened to me for several days after trying a high dose. It might be fine with the lowest dosage. Just be aware of this and listen to your body.
Thank you!
interested for sure.so, i see MANY different "brands" of this product, with a very wide range of retail prices!! how do we choose, or what do we specifically look for when deciding to make a purchase? thanks, and i too very appreciate your intro!!!
I've done a lot of research & learned that gluten sensitivity is a cause.
Thank you
great info thanks
Love your intro*
I believe he made a mistake at 7:29 with the pic of the mitochondria. He shows beta oxidation yielding "acyl-coa" but it should say "acetyl-coa" I believe acyl term is used anytime there is not an acetyl group attached to the coa.
One of the most informative videos about nutritional depression treatment! Kudos!
Is KUDOS A PILL FOR DEPRESSION? THANK YOU,
The answer it's not being tried on patients? BIG PHARMA
This was a very interesting, well done video - great job! I take Buspirone, which is a serotonin antagonist, so I'm wondering if it would be safe to try this in combination with it. I know with some of the natural supplements, you have to be careful, as the combination can cause serotonin syndrome. Has anyone tried this in combination with prescription antidepressants?
Thanks for the comment. I'm not aware of any published reports that address acetyl-l-carnitine / buspirone interaction. So, in terms of published information from medical literature, there's unfortunately no guidance on this.
@@AskAPsychiatrist Sure, I understand. Thank you for the quick reply though - much appreciated!
What about insomnia, seizure risk, and rapid tolerance?
My Strattera failed because of stomach issues and my dr recommended acetyl l carnetine telling me "I can get it vitamin or gym shops"
So thanks for this whole explanation bc I was VERY LOST on what was it supposed to do to me.
Strattera had me dribbling semen I know that’s tmi but I was like wtf. Disappointing because it did have some benefits at a low dose. A higher dose like 60 made me nauseous
Hi. May I ask if the studies showed how long before the acetyl l carnitine would start to work for depression? A few weeks, or immediately? I see one study that indicated it works in a few days instead of the usual few weeks it takes for a normal antidepressant to work.
Thanks.
I would see a naturopath to get the in depth information on this chemical, how you take, dosage and most reliable manufacturers
😅y
It works immediately!
I felt it immediately too 😊
I've heard about thyroid dysfunction with alcar, any information on that? That's the only thing stopping me from supplementing.
I tried a high dose and it gave me hypothyroid symptoms for several days. I do have hypothyroidism though, treated with T3 and T4 hormone. It rendered my medication ineffective. Maybe you could just try a low dose and see how it goes. If it does cause a problem it isn't permanent so it's not a huge deal.
What dose do you recommend? (Maybe I missed it in your presentation, sorry.)
Thanks
I have tried a few compounds including GABA. I do not think I want to do this again without a naturopath monitoring me. I felt shaky and a bit unstable. I am starting to feel using there poorly studied supplements interfere with or create more side effects with my meds
It's better if you can get support from an expert. Otherwise you just have to experiment cautiously and listen to our body.
thanks
Is it safe to consume alcar with a dose of zoloft?
18:12 ...because the pharmaceutical industry is crooked!
Is it OK to take prozac for many years if there's no side effects and it works?
I wouldn't. I'd be doing my absolute best to not feel the need to take it.
Rosanne, absolutely yes it is! By the way, I take both Paxil and ALCAR and they work together.
What dosage is good to take per day and should you take adults in the morning and then in the afternoon also should you cycle off of it?
I have read 2 grams a day twice a day
@@binathere2574 so you only take 2000mg per day total for the day correct?
@@perseverance9888 2000mg twice a day. I'm only taking it once a day the moment. In the a.m. I'm concerned about insomnia ATM. I already struggle with it, so I'm being careful.
I think start with lower dose and listen your body. And calculate your weight ...
I've tried it twice now. Both times it made me depressed. L Tyrosine works better for me.
How much alcar daily for depression
Will l carnitine also be effective in treating depression ?
What... he just covered that...
I cunsume 500mlg evryday and i had a headache as a side effect and it was terrible issue then i stopped it
Does it improve libido?
Yes
I’m not diagnosed with bipolar or any other disorder but I decided to start taking this along with alpha gpc to help me focus more in school. Now when I don’t take them in the morning shortly after I feel so empty headed and can barely think and process new information. I don’t know what to do other than to keep taking it to function properly.
It appears your body has adapted, stopping can cause withdrawal. I’m guessing that’s what’s happening.
I’d cut back on the alpha gpc, maybe do cdp choline instead
Why do you suggest CDP Choline instead? @@djammer
How about omega 3 ?
this worked the first day, didnt do jack afterwards.
Try it with ALA
Can anyone share dosages or which form they’re taking? I understand there is an “R” form
More superficial snake oil .
Oh dear.
Costs penny’s, not a big earner for pharma, try and see, many positive reports
Haha natural compound! Its the BigPharma that sell snake oil pal Kriminals in white coats😂😂😂
DOCTOR, I'M 57 FROM INDIA. WHY DOES MY ANXIETY AND DEPRESSION INCREASE MANIFOLD WHEN I TAKE ALCAR?
WOULD BE GRATEFUL FOR YOUR PROMPT RESPONSE.
THANKS
Everyone reacts differently to supplements. Listen to your body.
Try the simple L carnitin. Not the acetyl. May that works for you