Low Dopamine? Depression? Anhedonia? Meet, Pramipexole.
HTML-код
- Опубликовано: 27 апр 2024
- Pramipexole is a dopamine agonist medication primarily used for Parkinson's disease and restless legs syndrome. It's also being investigated as a potential treatment for depression, especially depression with symptoms like anhedonia (loss of pleasure in activities).
Here's a summary of the connection between pramipexole, depression, and low dopamine:
* Dopamine and Depression: Depression is linked to low dopamine activity in certain areas of the brain.
* Pramipexole's Mechanism: Pramipexole mimics dopamine by stimulating dopamine receptors, potentially improving mood and motivation.
* Research on Pramipexole for Depression: Studies suggest pramipexole might be helpful for some people with depression, particularly those who haven't responded to other treatments. However, more research is needed to confirm its effectiveness and determine the ideal dosage.
If you're interested in learning more about the research on pramipexole and depression, I can help you find credible sources. 
Хобби
I feel exactly what your feeling, I have been for a long time for at least 2 decades. I made some serious bad choices in my 30s to take care of that. Which turned my life upside down. I am a recovering addict and have been sober for 14 years. I just stumbled on to this video, and really don't have any info on your life up to this point. I can tell you that your describing exactly how I felt prior to making those negative decisions, and I feel even more so now that I don't self medicate anymore. Thank for sharing I believe I have a dopamine deficiency which I am in the process of getting labs done.
Appreciate you for sharing this 💪🏾💪🏾
Thanks Rich, happy to help 🙏🏻
Thanxfor Share
My pleasure!
Loved how you cut the fam off before they could be "helpful" I've been here too.
@@reniekittelhinnenberg8593 oh yeah, I definitely don't like that kind of help lol.
I feel ya brother
Thank you for this comment my friend!
I am cold turkey from that Mirapex. I was on it for 30 years.i am also at same time stopping ultrum . My world is a roller coaster right now.
I hope that that roller coaster stops soon my friend!
2days ago took an amount to bring me back to reality. But mainly safety.
What did you take it for? Where the side effects? Anything serious? Please explain whats happening to you
I've had a similar problem for a long time. Although this is something I would probably never be able to get prescribed or online. But I've thought of taking 9-me-bc.
I just looked into that. Looks amazing. I'm sorry to know that you're feeling the same way as me but I hope you find something that works for you.
I just ordered some for libido and mood as well as lowering prolactin while on nandrolone. Glad to hear the positive experience!
Happy to help! How is the nandrolone working out?
I had to stop taking nandrolone due to prolactin side effects like flat mood and low energy which is where Pramipexole kicks in. I think I had prolactin issues which tank dopamine my whole life. Very excited for Prami to arrive. I felt like you described in this video for a long time so again very excited. How are you now?
@@Ty44444 wow, I really hope that it helps you. I actually stopped taking it and went on testosterone which completely fixed my issues. With the Pami it would help me for about 2 days where I would then have to take more. It's not necessarily something I wanted to take continually. I got my blood work done and it said that my testosterone was low so after supplementing with testosterone everything went back to normal gratefully.
@@FromADistanceJewelryPramipexole is a game changer for me. It looks like prolactin was a big issue for me and this fixed it. I relate to what you said in the video I feel great and I can use my nandrolone without prolactin being an issue.
I think this stuff can help a lot of people 👍
Thanks for the video. I have similar problems. What kind of dopamine test did you get? Did it confirm low dopamine?
I got a prolactin test which would show low dopamine. It was in fact a tad low but the Dr didn't think it was low enough to cause the issues I was having. I started testosterone therapy (I did a video on it recently) and I've felt normal ever since.
Iv felt like that i just got a script i hope it works ill keep in touch jac
I'm happy to know that you're taking action against this problem! I hope that it helps you in some way! Something that has seemed to help me has been testosterone replacement! It appears that this has solved the issue that I was having. I've done a video on it where I discuss my process on coming to that conclusion. This might help you as well.
Been having the same symptoms for months. Also asked my doctor about this yesterday and he wrote me a script for 0.25 mg. I was gonna wait until tonight to take it. Did it make you tired?
Hey brother from UK. very informative video, thanks. Im very surprised i can order this online without prescription (legit pharmacy). Like you said, LAST resort. Do you still use it occasionally? Update?
Where
Wow, that's incredible! 👏 I haven't had to use it since I started taking TRT. I would absolutely use it again if necessary though. Very potent medication.
Its so hard to find someone that has adhd and has tried this med
I dont know how it is possible a quarter of 0.50 make sb feel motivated,since pramipexole mechanism of action what ive read is that in doses under 1 mg it downregulate those dopamine receptors actually its a big mental pain at first taking prami,and the mechanism is downregulating dopamine receptors for a while with doses under 1 mg will eventually sensitize your receptors when eventually you reach dosese higher than 0.75 and will be followed by dopamine flood .so im just wondering how this can happen with 0.25 mg of prami .i tried it once and at doses 0.25 mg (my initial dose) i got such a crippling worsening anhedonia and depressin that i quit ,i wish i could cope with initial mental side effects and titrate it up to 1 mg so it would be a relief on my anhedonia
That's interesting, it was the exact opposite for me. In fact, the information that I've read states that it acts immediately on dopamine receptors by releasing more. I'm sure that for everybody will be a little bit different just like with any medication.
OMG there is soo many people
In other meds that probably would better with a hormonal adjustment 😢
You're probably right my friend that's why I am pressing my doctor into looking at the TRT situation. Thank you for leaving your comments and opinions!
People using anabolic steroids (specifically 19 nors) use prami to reduce prolactin
That makes a lot of sense 👍
How’s it going now?
Hello my friend! I do not take this product religiously because it does have side effects that could be pronounced overtime. I take it on a per need basis. Other than a slight headache when I take it I haven't had any issues. I've also started taking testosterone replacement which has changed the game for me and help me with a much more positive outlook on life. I've done a video about that which I will be uploading to the channel soon.
you're anadonia may have been caused by a previous medication. if you cover that damage with synthetic dopamine, it will eventually make it worse. But I don't know your medical history. I wish you luck!!
@@SeanNorsee thank you my friend. I found out that it was because my testosterone was very low. Got that fixed and now everything is awesome.