Infectious Mononucleosis (Mono) Symptoms, Diagnosis, and Treatment

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  • Опубликовано: 10 июл 2024
  • Learn when to suspect infectious mononucleosis, how to confirm it with diagnostic tests, and how to tell it apart from strep throat and more dangerous conditions like lymphoma. In this video, you will also learn to interpret heterophile antibody tests and specific serologic tests for EBV (Epstein-Barr virus), the cause of infectious mononucleosis. You will also learn about potential complications, recovery, and when it's safe for patients with mono to return to school, work, and sports.
    If you want to learn how to recognize life-threatening infections like sepsis and CNS infections as early as possible, I highly recommend you take my free online course!
    A Clinical Approach to Serious Infections in Adults: What Every Physician Should Know:
    drviktorkotarski.podia.com/re...
    DISCLAIMER: Please, always keep in mind that my videos are intended for educational purposes only. The content of my videos is NOT medical advice. I do not practice medicine over the internet. If you are a patient and have any questions about your health, please talk to your doctor.
    CHAPTERS:
    00:00 The problem with infectious mononucleosis
    00:45 Epstein-Barr virus (EBV): the cause of infectious mononucleosis
    01:00 Transmission of mono in children, teenagers, and adults
    02:04 Basic pathophysiology of Epstein-Barr virus infection
    02:29 Symptoms of infectious mononucleosis (mono)
    03:24 Lymphocytosis (B cells and atypical lymphocytes) in mono
    05:06 Infectious mononucleosis vs. strep throat and other causes of pharyngitis
    06:13 Laboratory abnormalities in infectious mononucleosis
    07:07 Serologic tests for EBV (antibodies for EBV like VCA IgM, VCA IgG, and EBNA IgG)
    08:45 Heterophile antibody tests for mono
    10:00 Differential diagnosis of infectious mononucleosis
    12:45 Treatment of mono
    14:00 When to return to work, school, and sports after mono
    RESOURCES & RECOMMENDED READING:
    1. Dunmire SK, Hogquist KA, Balfour HH. Infectious Mononucleosis. Curr Top Microbiol Immunol. 2015;390(Pt 1):211-40.

Комментарии • 95

  • @t.h.8475
    @t.h.8475 8 месяцев назад +36

    I got mono when I was 20. I was married, I had no idea how I got it. I've had what was believed to be strep throat since then dozens of times. I think those times it was mono. Thank you for educating us.

    • @peanut422hb
      @peanut422hb 6 месяцев назад

      We get viruses in our childhood 💉💊

  • @TributeMack2015AngrierMack
    @TributeMack2015AngrierMack 7 месяцев назад +18

    Once I had mono when I was 13. I began to cry because how bad the pain is I’m 20 now and I hopefully will never get that again.

    • @sunflowersunflower5669
      @sunflowersunflower5669 5 месяцев назад +2

      Mono stay in your system forever and lays dormant for years. Hopefully, you don’t have the symptoms again.

    • @casperinsight3524
      @casperinsight3524 2 месяца назад

      ​@@sunflowersunflower5669
      That's depressing 😞 sounds like a latent virus that can become reactivated under circumstances of poor health or high stress 😬

    • @TributeMack2015AngrierMack
      @TributeMack2015AngrierMack 13 дней назад

      No. Not really it usually goes away about 3-4 weeks and no it’s doesn’t necessarily mean it’s curable it’s can be treated. I had it when I was 13 years old. Now I am 20 I really don’t get it anymore.

  • @kcandyou5263
    @kcandyou5263 7 месяцев назад +8

    I had mono junior year of high school. I was 16 went from 116 pounds very strong in weight training to 90 pounds and so weak. My tonaila qere so swollen they touched and were all white white. My neck was so swollen outward from my lynph nodes it looked like i had baseballs on the sides of my neck and any movement hurt.
    It took a long time to fully recover. I am so glad i finally got it my tonsils out at 19. I had strep throat so many times from 14 yrs old on then after mono constant sore throats. The Dr said when he sliced them out puss oozed out of them. It was like a permanent state for them and id never have gotten better.

  • @Hannah-rr7gn
    @Hannah-rr7gn 25 дней назад +6

    I’m 18 and have mono right now and it is no joke! I’ve had Covid 3 times and this is by far the worst. I’ve been in so much pain and have been crying.

    • @aspenohlrogge6646
      @aspenohlrogge6646 24 дня назад +1

      Me too💔

    • @devariuskelly258
      @devariuskelly258 23 дня назад

      kid you not this is my exact situation 😭 18 been to the hospital for it already im on like day 10. Praying for a quick recovery for you🙏🏾

    • @devariuskelly258
      @devariuskelly258 23 дня назад +1

      saved ur playlist btw haha thats awesome Jesus got you girl dont stress we serve an Amazing Creator🖤

    • @br4252
      @br4252 16 дней назад +1

      bro so much worse than covid. I have never had this much pain ever. I cant eat or even drink

    • @flipwhale5494
      @flipwhale5494 6 дней назад

      @@devariuskelly258in Jesus’ Name Amen 🙏🙏❤️❤️✝️✝️🕊️🕊️

  • @ivanaoslakovic1364
    @ivanaoslakovic1364 9 месяцев назад +8

    Ono kad tražiš razlike strepta i mono na youtubeu (i moliš Boga da samo dobiješ antibiotik i ne pokvariš velike planove), naiđeš na Hrvata kojeg poslušaš od a do ž jer je tako zanimljiv. 🤓
    Oh well... Kao što to biva, uvijek se nekako razbolimo petkom navečer ili vikendom. Hitna, here I come! xD.
    Great video, doktore.

  • @GardenerRose
    @GardenerRose 4 месяца назад +2

    My son was in the LA airport for layover ! He said it was so dirty got home and had a rash on face soar throat, he arrived at his usual self, but within a few days, he became so tired he couldn't get out of bed ! Waiting to hear his results if its mono

  • @gsav1320
    @gsav1320 6 месяцев назад +23

    I have this shit rn and holy shit does the sore throat hurt

    • @keishat.8377
      @keishat.8377 5 месяцев назад

      I hope you feel better now. It lasted from the end of 2022 December to March 2023 I slept so much other was so bad

    • @tinytaylor1109
      @tinytaylor1109 4 месяца назад

      Fr I have it rn too :/

    • @keishat.8377
      @keishat.8377 4 месяца назад +1

      @@tinytaylor1109 I hope you feel better I had it for 4 months didn’t know for the first month because I wasn’t tested for it

    • @demetriusjohnson4231
      @demetriusjohnson4231 2 месяца назад

      I went to urgent care this week and got tested for it but the doctor said it takes around 2 weeks for it to come up positive. I feel like I have it and im struggling right now

  • @gabrielpalmarini9003
    @gabrielpalmarini9003 2 месяца назад +8

    This shit fucking hurts

  • @AR-uj5fe
    @AR-uj5fe 2 месяца назад +5

    Had mono since January until now and symptoms are mostly nonexistent for me except how it’s difficult to swallow solid food and I have this lump in my throat that makes it hard to breathe and won’t go away. It’s affected my day to day life and I’m scared that it could potentially get worse. It’s already been so long and I feel like this :( I do hope doctors will come up with a vaccine/medication to fight this virus. It really sucks for us who have to deal with it and recover for such a long time 😔

    • @robertf.8916
      @robertf.8916 2 месяца назад +1

      You’ve had it for so long?? What symptoms exactly and how did you discovered it was mono? I’m having lymph nodes on neck white dots on my tonsils and headaches and fever once in a while and a bit of fatigue. I’ve been like this since a week, but waiting for my doc appointment

    • @AR-uj5fe
      @AR-uj5fe Месяц назад

      @@robertf.8916 Sadly yes. My first discovery was sudden dysphagia. I suddenly couldn’t swallow my food anymore. Over time I’ve gotten a sore throat, had these little red spots on the roof of my mouth, fatigue, and my epiglottis sticks up! Apparently that can also occur when you have a viral infection. I was sent to the er back in April because it felt like my airways were going to close. That’s where they diagnosed me with Mono. Best they could do is give me steroids and IV fluids. I was then sent to an ENT where they performed a nasal endoscopy to make sure it wasn’t anything more serious. Everything was normal. Even now, there’s nothing I can do but try to eat (and healthy ofc), drink lots of fluids, and try not to stress because you can relapse from mono and or delay your recovery by stressing yourself out and not giving your body the proper rest. Could be why it’s been with me for so long; almost HALF A YEAR!! It’s nuts

    • @AR-uj5fe
      @AR-uj5fe Месяц назад

      @@robertf.8916 If you can, ask your doctor to give you steroids. Prednisone Steroids to be exact. Apparently it’s helped a lot of ppl recover and reduce the inflammation as well as the swelling of your lymph nodes, spleen and liver.

    • @aayushigoel181
      @aayushigoel181 Месяц назад +1

      I feel your pain. I m unsure if doctors here diagnose us on a serious note but they said i have this infection since march and till date, i have swollen cervical lymph nodes with swollen entire neck on left side and some sores at back of throat. I don’t know when its gonna go away or i have to live with this forever

    • @AR-uj5fe
      @AR-uj5fe Месяц назад

      @@aayushigoel181 Honestly same for me but we can get through this. I’ve been eating lots of healthy food, especially leafy greens and fruit. My energy levels are a little better but I still have trouble eating normally. It’s difficult but it’ll pass, I know it. See if you can get prednisone steroids to help loosen your lymph nodes and tonsils, apparently it’s helped a lot of people make their symptoms go away. As for pain, gargle salt water and take pain killers.

  • @Cece_m2
    @Cece_m2 4 месяца назад +3

    Could it be possible you can get it from clinic equipment? I visited an ENT clinic because I saw a one white like a ceast on my throat..my throat at that time was clean and the tonsil is not big. It's like a thin skin on my mouth. The clinic said it was just a fat that was built. After I visited the clinic, few days after I sneezed the whole night and my tonsil swollen and I noticed my tonsil got bigger . Now, it's been 5 months still big and I now saw white spots tho I tried antibiotics for a week before I saw these white substances.

  • @deanmason5827
    @deanmason5827 9 месяцев назад +4

    I am 62 and have been diagnosed with Mono, I know it's a lot of fun, I do however have no, zero, none of the sore throat glands or any of the neck glands, now I am worried, back to the Doctor.

  • @owenthfc9055
    @owenthfc9055 День назад +1

    I am on day 4. Fever, headache, dizziness has gone but I still have the sore throat. How long until my throat feels better?

  • @BrianGemberling
    @BrianGemberling 2 месяца назад +2

    Unbelievably clear and detailed explanation and differential analysis

  • @mjcreadingvideos8079
    @mjcreadingvideos8079 9 месяцев назад +3

    Great information! Thank you!

  • @AmitisL
    @AmitisL Год назад +2

    Very helpful, thank you

  • @sueregan2782
    @sueregan2782 4 месяца назад +5

    I came down with mono in 1970 and never fully recovered. Took about a year for the white blood cells to return to normal, but for the next two years of active duty military service I just did my shift and went home to bed. Any extra activity like driving for a day caused temp to go to 101 F. Then, after about 20 years I developed full blown ME/CFS, and all the tests said I had active mono or Epstein-bar. Eventually I couldn’t walk and numerous tests eliminated all other causes. Since it was well documented that I had acquired this while on active duty, the VA easily awarded service connected disability support.

    • @casperinsight3524
      @casperinsight3524 2 месяца назад

      Sorry to hear your plight 😞
      Anyone who has had to deal with chronic ongoing health struggles knows how debilitating and sad it is to live life on the sidelines.
      May your health be restored 🙏🏼 and life be enjoyed fully once again 💞

    • @casperinsight3524
      @casperinsight3524 2 месяца назад

      Sounds like you were diagnosed by conventional mainstream doctors. Do you recall what specific tests or markers revealed your diagnosis ?
      Appreciated ~ Thank you for sharing

    • @casperinsight3524
      @casperinsight3524 2 месяца назад

      Receiving Disability was a fortunate Saving Grace at least 🙏🏼🤍

    • @sueregan2782
      @sueregan2782 2 месяца назад

      @@casperinsight3524 I was an Army nurse working on medical & cardiac intensive care, where we treated leukemia patients. When I first experienced muscle pain & fatigue they did a CBC and mono spot, both negative. But six weeks later, still working but more symptoms like coated tonsils, enlarged liver and spleen. They repeated the tests one evening when I got to work. When the lab called, the lab tech was shocked when I answered the phone. She hung up and re-ran the test, which was worse than any of our leukemia patients (who she had presumed it was). They put me in the hospital while awaiting the new mono test which was positive. About six months later a doctor noticed that I had a headache. He didn’t believe me that it was mono because the medical books said it only lasted eight weeks. When that test came back positive, he pulled my record & entered a diagnosis of chronic active mono. It was because of this that the VA was able to confirm that I had a service connected disability 25
      years later when I got to where I couldn’t walk. All current tests came back positive for mono or Epstein Barr. The VA hospital doing my tests was treating me for cancer at the time, so every test known to man was done repeatedly, so they confirmed my diagnosis that was used for my disability evaluation. (It is totally separate from the hospitals, but could pull my records.)

    • @sueregan2782
      @sueregan2782 2 месяца назад +1

      @@casperinsight3524 Yes. God provided twenty five years before I had the need. Read my story below. One miracle was that my Army records did not get destroyed in the 1973 records fire so the VA was able to recover my Army records. Also, I did not know until then that a doctor had entered a diagnosis while I was still on active duty. .

  • @staceyrosado6402
    @staceyrosado6402 7 месяцев назад +6

    My child just got diagnosed with mono she was hospitalized for days before they came up with this. Her spleen and gallbladder was swollen and she had so much pain we were in the hospital for three days the day we came home she had high fever an couldn’t swallow and breathing was a problem. IM SO UPSET WHY IS THERE NO VACCINE FOR THIS WHY IS THERE NO CURE FOR this! I’m so upset she has to deal with this her whole life.
    I’ll say my husband used a breathing treatment that we used for Covid and the next day she was 70% better used it again was 50% better she’s doing so good now that we took her treatment in our own hands

    • @Bodyandsoulreconnection
      @Bodyandsoulreconnection 6 месяцев назад +1

      Hi. How distressing for all of you Glad to hear that a breathing technique improved your daughters condition. Can you please let me know if this is the technique you used? If not, let me know if there is another video that demonstrates it. Thank you.
      ruclips.net/video/bBkGDIeQwXo/видео.htmlsi=ECztSs90qadTVJxR

  • @sandrabz21
    @sandrabz21 5 месяцев назад +1

    Awesome videos, Victor. I am Croatian myself currently practicing medicine in Brentwood, California

  • @niecek.6473
    @niecek.6473 10 месяцев назад +1

    Great video! Thank you!

  • @JJ_Beats._.
    @JJ_Beats._. Год назад +5

    Is it normal to have no sore throat at all? The first symptom I had was lymphadenopathy of the supraclavicular region, under arm, cervical and inguinal regions followed by extreme fatigue, stuffy nose, headaches and stomach pains for 2 months.
    Im 25 so my doc said its likely glandular fever but is it really since I've not actually had a fever or sore throat?

    • @missharris5521
      @missharris5521 2 месяца назад +1

      Did u find out because i am same no sore throat or fever

  • @ivazadro5857
    @ivazadro5857 Год назад +1

    Hvala puno

  • @adamhunter4120
    @adamhunter4120 4 месяца назад +2

    I got mine 4 years ago and it never went away it’s caused CFS

  • @Kingaronfi
    @Kingaronfi 2 месяца назад +1

    i am 30 and i just got mono a month and a half ago. im really struggling. they just think its mono because i tested positive but they say the test is not always right so they took like 20 small glass things of blood day after day. i had an infetion and a cold and spleen pain and splenic infarction and i puked once not much and i had eating problem. couldnt eat almost anything. i called the hospital and they took me in right away. been there for 4 days or maybe longer. i struggled to walk because spleen pain and pain in spleen from breathing. now im home and been waiting almost a month for my results of if it is mono or something else, they are very slow and they have cancelled 3 times. i have to use blood thinners so that the blood clot in the spleen wont spread or get worse. so the day they sent me home i had so much pain but the hospital was very full and i was doing better. when i got home i felt better every day. but my other symtom is pain in the left shoulder neck area and i struggle to walk up and down the stairs because of breathing problems from mono. yesterday the pain was worse but got better today but not by much. so i need to use blood thinners needle every mornings and before bed. and i feel tired all the time.
    does anyone have any advice or know for sure that this is mono? not sure where i got it but my girlfriend have had is as a teen, and we kiss alot. and we have been eating fast food some times.

    • @sueregan2782
      @sueregan2782 2 месяца назад +1

      All the symptoms you are having can happen with mono. The enlarged painful liver and spleen are caused by the abnormal white blood cells building up and can be dangerous. So, need to be gentle. Important to rest and not push yourself. Keep hydrated and nourished as much as possible.That is the only way to heal. I had all that and it took over a year for my blood count to approach normal. The liver & spleen slowly reduced and I was returned to work after a couple of months, but spent all my off duty time in bed with a low grade fever.

    • @Kingaronfi
      @Kingaronfi Месяц назад

      @@sueregan2782 is it also common to lose more hair than normal? i am starting to walk a bit more now after a long while. i walk alot in nature but i usually walk slowly and mostly flat grounds to be safe. i feel like walking have helped me alot through all this. the doctor said i could start workingout again but with smaller weights but i still feel some pain so i will wait a bit longer. maybe 1 month extra or more. i will listen to my body and try to take things slowly

    • @aayushigoel181
      @aayushigoel181 10 дней назад

      I am unsure about you but i am dealing this shit since march and everyday comes with a surprise of new symptom to me. I am almost convinced that i have cancer of some sort- either an oral cancer or lymphoma because this fucking sore throat doesn’t heal and lymph nodes is still the same , plus i feel 2kg weight on my neck and shoulder and arm on left side due to swelling and muscle stiffness. My swelling comes and go on its own. Dr says i need mental
      Support because i keep
      Going back
      To emerge due to my anxiety if i am
      Dying soon. Fortunately, i do not have trouble eating rn but i don’t know if anyone had this bad experience with mono. I also
      Have hashimoto thyroditis. My life is fucked up. God is the only hope for me. I cry everyday that i am
      Dying As i don’t trust any doctor in canada.

  • @frugalbee7250
    @frugalbee7250 Год назад +2

    Excellent

  • @Essie2222
    @Essie2222 4 месяца назад +2

    Absolutely what I am going throughout for years!!!! It never goes away it comes back in flares. Makes me hopeless 😢 i have fibromyalgia diagnosed now

    • @casperinsight3524
      @casperinsight3524 2 месяца назад

      Could mono pull the trigger for auto immune diseases ? 🧩

    • @sueregan2782
      @sueregan2782 2 месяца назад

      @@casperinsight3524 For some people yes. But more likely for chronic EBV (mono virus).

  • @MyHiddenWrld
    @MyHiddenWrld 7 месяцев назад

    yeah i took that med for my tonsils and now i got red spots all over me :/
    update i dont got mono just allergic reaction to the med i took

  • @parisdrekoudis
    @parisdrekoudis Год назад +5

    Could you please do a video on antibiotics spectrum? Thank you so much!

    • @clinicaltips8926
      @clinicaltips8926  11 месяцев назад +1

      I'm afraid a video like that would be 6 hours long:D I mention the key points about the spectrum of the most widely used antibiotics when I do a video about a specific infection.

    • @parisdrekoudis
      @parisdrekoudis 11 месяцев назад +2

      @clinicaltips8926 though it would be extremely useful. If you have the time please do it. Important things-ideas must be"born". I believe it will be a milestone in education.

    • @user-dp7hn4rm2r
      @user-dp7hn4rm2r 4 месяца назад

      That is

  • @jamesscober5307
    @jamesscober5307 5 месяцев назад +2

    This is way to technical for me. I just want my 9 year old daughter to get better after being diagnosed with MONO

  • @AilaSharon-rt2be
    @AilaSharon-rt2be 9 месяцев назад +5

    My situation right now but I don't know what to do can you help me please

    • @rangonegar
      @rangonegar 8 месяцев назад

      Hello. I have mono now. How long will it take to get better?

    • @thewellbeingqueen_
      @thewellbeingqueen_ 8 месяцев назад +2

      @@rangonegarthe acute phase is around 7-10 days. Then the recovery phase can be around 6weeks. This is where you’ll feel intense fatigue and maybe headaches or muscle pain and weekness.
      Rest up and stay hydrated and don’t plan on anything for the next six weeks except resting and healing. I’m sorry you’re so unwell. But you will get better.

    • @rangonegar
      @rangonegar 8 месяцев назад

      @@thewellbeingqueen_ tnx a lot. this situation is very difficult for me and I am more worried about the complications of the disease. I am now on 25th day and i feel better

    • @michellem.m.1477
      @michellem.m.1477 2 месяца назад

      @@rangonegarhow are you now ?

  • @ameen88
    @ameen88 6 месяцев назад +1

    Is it ture that people how contracte mono raise the risk of contacting ms disease

    • @eyeswideopen7777
      @eyeswideopen7777 5 месяцев назад +1

      It's just a study, remember? Another opinion doesn't mean 💯 true or factual. I knew someone grew up with a house full of mold, coincidence? His aunty also has mono. He started at 22, getting it. He's 30.

    • @eyeswideopen7777
      @eyeswideopen7777 5 месяцев назад

      There was a guy saying he took Pfizer shots and now has diagnosed multiple sclerosis

    • @casperinsight3524
      @casperinsight3524 2 месяца назад

      ​@@eyeswideopen7777
      It's not coincidence imo but a very real and serious catalyst for various autoimmune diseases

    • @jazminetwittytherapper5624
      @jazminetwittytherapper5624 Месяц назад

      I had Mono, I now have MS.

  • @IsaacMtonga-cg2bo
    @IsaacMtonga-cg2bo Месяц назад

    Am having tonsils Three days now and it's hurt

  • @YuiYui-uq2nu
    @YuiYui-uq2nu Год назад +2

    From croatia?

  • @user-jq9wf8dk9k
    @user-jq9wf8dk9k 10 месяцев назад

    Let's go

  • @RavenWolfDrum69
    @RavenWolfDrum69 7 месяцев назад

    I think i had it once

  • @chriskerwin9050
    @chriskerwin9050 3 месяца назад

    Better look out for ms later it has been linked to mono

  • @OfficialAppYT
    @OfficialAppYT 5 месяцев назад

    Bro I got mono when I was 8💀

  • @user-yx6mz5rc2x
    @user-yx6mz5rc2x 4 месяца назад

    Guy’s in the comments stop 🛑 going to San Francisco for vacation…???????😂😂😂😂

  • @eyeswideopen7777
    @eyeswideopen7777 7 месяцев назад +1

    Its a kissing disease

    • @god563616
      @god563616 5 месяцев назад

      I've never kissed anyone.

    • @casperinsight3524
      @casperinsight3524 2 месяца назад

      That's the popular rumor 😉
      But it's more likely transmitted by cross contamination through cutlery, glass, mug or water bottle, shared straw
      Possible buffet without sneezeguard
      Unwashed fruits & veggies
      Infected doorhandles, etc
      Possibly transmitted through someone sneezing or coughing
      Physical acts of "intimacy"
      Sharing a cigarette, blunt or pipe
      putting end of pen or pencil in mouth in school, home or office
      transmitted hand to mouth or through sinuses ?

    • @casperinsight3524
      @casperinsight3524 2 месяца назад

      It's passed through saliva without symptoms as in the shedding phase 👀

  • @casperinsight3524
    @casperinsight3524 2 месяца назад

    Your video may have just connected possible invisible dots 🤔
    Misdiagnosed Mono or EBV may explain chronic fatigue ...ding ding ding alarm bells sounding 🤯 perhaps you found the missing pieces of the puzzle...? 🧩 👀

    • @_aleksis.k9484
      @_aleksis.k9484 Месяц назад

      How you doing?

    • @casperinsight3524
      @casperinsight3524 Месяц назад

      @@_aleksis.k9484
      mono or EBV came back negative so back where I started 🙄

    • @casperinsight3524
      @casperinsight3524 24 дня назад

      @@_aleksis.k9484
      Still piecing the puzzle 🧩 hope you are doing well 🙏🏼

    • @casperinsight3524
      @casperinsight3524 12 дней назад

      @@_aleksis.k9484
      Still piecing it together 😉