You're the only reason I'm going to pass pharmacology this semester. Your depth of knowledge and understanding astounds me with every lecture. This is my very first RUclips comment ever and it's well deserved!! Keep kicking ass!! THANK YOU!!!
He really fills in all the gaps that my professors seem to skip over. This guy has saved me so many times. I just want to remind everyone to like his videos and subscribe to his channel. I mean if you watched any part of his videos or the entire thing. It is nothing for us but helps him out so much. I appreciate this channel and all the work that goes into it. Keep up the great work.
I just came from my cardiologist’s office and wanted some information on beta blockers, which he just prescribed. Your lecture was done so well that I watched it to the end and was surprised at how understandable you made it. Thank you! I’m sure you really ARE helping those commenting below get through medical courses with how well you teach the material.
Thank you very much for taking the time to explain the three kinds of Beta blockers. For years I have taken atenolol for angina. Started in 1981. I am now 74 years old and have calcification in my heart. The doctor has taken me off atenolol and put me onCarvedilol. Your video is so good that I am going to watch it for the second time. I am very grateful to have found your video
For some time (around Two years), I was maintaining my prescription medication to keep my high blood pressure not until this month I recently found about this t.co/GsO1JmyXtf therapy. A doctor has verified it too. Really dont require the drugs previously prescribed to me. .
I have learned more from this video than i have from any teacher or book!! Your teaching style is amazing and so helpful!! I am hoping watching this videos will help me pass my advanced pharm class! keep the videos coming!!
Am so blessed i found you 😭😭 I am having exams in a month i want more PHARMACOLOGY LECTURES PLZ SR upload them you are the only teacher whom i understand pharma . No other channels helps me,😭😭
I am a Dentist and I'm studying to take the Dental Boards! your videos are the only ones that help me comprehend better! I can't Thank you enough! You are the best!
Check out the Discord! We have a section created for Dental students, with specific topics relevant to those studies! Plus, you'll find other Ninja Nerd community members who are studying Dental fields.
As someone who just started taking bisoprolol this video really helped understand what's actually supposed to be happening, what's going wrong and how the beta blockers will fix it as well as all potential risks! Big thanks! 😊
You are the best tutor that I have ever had. Thank you so much, I presented β-blockers to my master program and I felt very confident after your video. Well done!!
You explain it all so very well. You draw the map so completely between all the systems so when I making driving my car trying to decide which way to go I have your road map to make clinical decisions. You were great I love you
Nebivolol: A Novel Beta 1-Blocker with Nitric Oxide-Induced Vasodilatation very unique among other class . Good tolerability.Nebivolol is approved in Europe/Asia/Africa and Middle east countries widely used . ( particularly in asthma and COPD patients where other beta blockers are contraindicated)
Can you, please, explain "cytokine storm" as it applies to Covid19? Particularly IL-6 (interleukin6) and its medication anti medication. I think you're very brilliant and consider it a blessing to have you with us. Is there another way of giving donations that aren't done via internet? It's very important to help you with your mission...
Love your content, it's saving me right now! Small point, but I learned that an indication for beta blockers in heart failure is to offset the ongoing effects of sympathetic activation in CHF. Obviously the sympathetic effects are good in acute settings, but in chronic settings the sympathetics are part of what leads to the pathophys of chronic CHF. I feel like that fills in a gap when you discuss indications! The ongoing compensation via autonomics can (paradoxically) lead to decompensation via physiologic/structural changes, but once the patient is decompensated you don't want to interfere with the autonomic compensation response because it is too little too late.
I absolutely love this channel. It's the only thing keeping me sane through FNP school. I may have listened to "double block that AV node" a few too many times but it helped me remember not to give beta blockers and calcium channel blockers together!
You are the very best. Occasionally, when going over important concepts, it might be best to slow down a bit on the speed of your speech. Because you are so familiar and well versed in the subject, I can understand why you feel the need for speed in order to cover the subject completely in the short amount of time you have. Nonetheless, you are the VERY BEST lecturer I have ever encountered in my life.
Some Ninja Nerds who have had issues with Zach's speed have reported setting the playback speed to x0.75 helps them! It's hard to contain his exuberance sometimes!
First RUclips comment, thank you for all your lectures you are absolutely amazing. All health professionals and future health professionals continue to benefit from your astounding lectures. I love your content- thank you x1,0000,00000
How do you study for this kind of presentation? your Method of study is behind all this powerful, simple presentation. I just begin my Pharmacology 1 at PNG Uni of Med & Health Sciences. Thank you for lifetime proff
Thank you for the awesome overview. The labeling of the funny Na++ channel inside the pacemaker cell is "Ca++" (should be Na++) - around minute 23, 24 in the video.
I'm not a Med student but I love your presentations. I am a retired electronic engineer and now believe the human race runs on cellular MilliVolts levels and other chemical interactions I have yet to understand. Thanks!
I love your in depth explanation and rationale for each drugs, very informative and easy to understand. well done and keep the good work. Well recommended. Good bless and keep safe.
LOL, simple concept, right? I'm off to get my alcoholic beverage to act on my overstimulated brain cells. I truly appreciate how this is all broken down VISUALLY so that I can truly grasp the concepts. This is the first and only site I go to for pharm and theory. Thank you so much!
Another amazing video, keep up the good work! You’re getting my whole class through pharmacy school. You deserve a shout out at our graduation. I couldn’t thank you enough.
Great Job! I love watching your videos! They help me a lot at med school!! I would like to ask, if you’ve got your beta-adrenergic receptors blocked, and you want to raise your HR with atropine, which blocks the muscarinic receptors. Who’s gonna act? My point is, if your circulating catecholamines can’t bind to their receptors (because they are inhibited by the beta-blockers), why would you give an anti-cholinergic? I mean, you would be blocking the sympathetic and parasympathetic at the same time. I think that you should give something to displace the beta-blockers from their receptors, for example, isoprenaline. This is all my point of view, if I’m wrong, please let me know!! Because the best way of learning is through discussing knowledge. Anyways, I enjoy studying with your videos! You are extremely great, and you explain thousand times better than all of my med school teachers! Hugs from Argentina 🇦🇷! Sorry for my horrible English!!!
I got prescribed propranolol for anxiety after alcohol withdrawal, and, true to form, taking them has started causing me anxiety, lol. They do work really well for reducing the sweats, shakes, tachypnea and tachycardia, but they don't directly impact the mental aspect- one could even say that they approach anxiety from the other direction that benzos do. Benzos calm the brain, which calms the body, Inderal calms the body, which allows the mind to calm down. So now I'm watching videos like this one, so I can calm my hypochondriac ass down further, lmao. It's helping, too, so thanks. I'll dazzle my doctor with my knowledge during our next visit.
More pharma please dr zach we need videos of analgesics and Local Ansthesia and many moreeee also please continue the microbiology series general medicine General surgery topics will be appreciated Thank you for the explanation and the effort that you put in your videos
i really can't thank you enough man thanks for all the hard work u r putting in this channel and for your efforts god bless and keep up the hard work :D
A friend closed to me have used also this t.co/GsO1JmyXtf high blood pressure treatment I stumbled upon on His blood pressure levels was stroke level 158/120. The result of the program can be seen right away especially if you eat the proper foodstuff. Right after Two weeks, he has seen a gradual decrease in his high blood pressure to 128/84.
Trying Propranolol for migraine prevention (day three so far). I also have extrne levels of generalized anxiety and slightly high blood pressure. Week long migraine gone as of yesterday. No negative side effects so far.
Intriguing. My BP before propanol was high with migraines and anxiety. Now my BP is either still high or super low. My thinking is leaning to me to Pheochromocytoma.
Ninja Nerd you are the best! At first I found the topic hard to connect in such systematic way, but you made my day a lot easier. Are you MD? Resident? What kind of qualification do you have?
I've just been diagnosed with SVT. I currently have DVT, PE, COPD-2, PAD and CAD. Checking what side effects Beta Blockers have. General, instead of being bedridden or close to it. I'm now going to be able to slow my tachycardia but now loose more quality of life due to diarrhea, increased edema, vision problems (had Glaucoma since 2000),... It seems the best move now is to purchase a 38' because I will never have any quality of life ever again. My entire family is gone, what friends I had are no more. I live in a van with the minimalist of life's aids with no Healthcare luxuries. From what I could understand and learn, the Second Generation might help...but again, too many negative side effects especially living alone. Praying doesn't work anymore.
I take carvedilol and lisinopril for high blood pressure. I have mild diastolic dysfunction and mild aorta widening as well as long QT Syndrome. I love your videos and indepth explainations!
Great video - very informative! I am confused on the effect of sympathetic stimulation on beta cells of the blood vessels in the video (8:05). I think it causes vasoconstriction, but in the video you said it is vasodilation which supports increase in BP too. Am I missing something? 😬
blood vessels have different types of receptors (alpha 1 & beta 2...) which are localised as so: alpha 1 are localised in arterioles all over the body expect coronary arteries and vessels that supply the CNS ,which have beta 2 receptors...so that when you have an activation of sympathetic nervous system or you are on shock the vasoconstriction does not affect the vessels supplying the brain and the heart thus maintaining their function.... (I guess)
![Gunna - HIM ALL ALONG [Official Visualizer]](http://i.ytimg.com/vi/HiCxoDeo0hc/mqdefault.jpg)
You're the only reason I'm going to pass pharmacology this semester. Your depth of knowledge and understanding astounds me with every lecture. This is my very first RUclips comment ever and it's well deserved!! Keep kicking ass!!
THANK YOU!!!
He really fills in all the gaps that my professors seem to skip over. This guy has saved me so many times. I just want to remind everyone to like his videos and subscribe to his channel. I mean if you watched any part of his videos or the entire thing. It is nothing for us but helps him out so much. I appreciate this channel and all the work that goes into it. Keep up the great work.
I just came from my cardiologist’s office and wanted some information on beta blockers, which he just prescribed. Your lecture was done so well that I watched it to the end and was surprised at how understandable you made it. Thank you! I’m sure you really ARE helping those commenting below get through medical courses with how well you teach the material.
Thank you very much for taking the time to explain the three kinds of Beta blockers. For years I have taken atenolol for angina. Started in 1981. I am now 74 years old and have calcification in my heart. The doctor has taken me off atenolol and put me onCarvedilol. Your video is so good that I am going to watch it for the second time. I am very grateful to have found your video
I'm never not impressed when watching these videos. The breadth of your biological and anatomical knowledge is really astounding and enviable.
For some time (around Two years), I was maintaining my prescription medication to keep my high blood pressure not until this month I recently found about this t.co/GsO1JmyXtf
therapy. A doctor has verified it too. Really dont require the drugs previously prescribed to me. .
14 mins in and I just know I have myself a new tutor. Excellent. Bravo. I'm speechless
The best teacher ever I did learn this subject 40 years ago in Bucurest Romania ago, I remember all, you are amazing. Thank you
I have been watching Ninja Nerd for a few months now and i think no one can explain better than these videos man !
Starting my Pharmacy Degree next year and I can already see that your videos are going to extremely helpful.
I have learned more from this video than i have from any teacher or book!! Your teaching style is amazing and so helpful!! I am hoping watching this videos will help me pass my advanced pharm class! keep the videos coming!!
Am so blessed i found you 😭😭
I am having exams in a month i want more PHARMACOLOGY LECTURES PLZ SR upload them you are the only teacher whom i understand pharma . No other channels helps me,😭😭
I am a Dentist and I'm studying to take the Dental Boards! your videos are the only ones that help me comprehend better! I can't Thank you enough! You are the best!
Check out the Discord! We have a section created for Dental students, with specific topics relevant to those studies! Plus, you'll find other Ninja Nerd community members who are studying Dental fields.
@@NinjaNerdOfficial really? Omg thank you so so much! ❤️❤️❤️
you are the best teacher I have encountered in science. I really appreciate you.
Best medical lectures on the web. Great content, great attitude. Keep it up.
this man understanding of the topic is astounding
Thanks for helping me through nursing school!!
As someone who just started taking bisoprolol this video really helped understand what's actually supposed to be happening, what's going wrong and how the beta blockers will fix it as well as all potential risks! Big thanks! 😊
You are the best tutor that I have ever had. Thank you so much, I presented β-blockers to my master program and I felt very confident after your video. Well done!!
You explain it all so very well. You draw the map so completely between all the systems so when I making driving my car trying to decide which way to go I have your road map to make clinical decisions. You were great I love you
Nebivolol: A Novel Beta 1-Blocker with Nitric Oxide-Induced Vasodilatation very unique among other class . Good tolerability.Nebivolol is approved in Europe/Asia/Africa and Middle east countries widely used . ( particularly in asthma and COPD patients where other beta blockers are contraindicated)
That’s really cool!!! Thanks for sharing that!!!
Can you, please, explain "cytokine storm" as it applies to Covid19? Particularly IL-6 (interleukin6) and its medication anti medication. I think you're very brilliant and consider it a blessing to have you with us. Is there another way of giving donations that aren't done via internet? It's very important to help you with your mission...
Hi dear thanks so much
Love you Sir...How much complex is the topic doesn't matter. .He makes it simple in so many ways. ..
Love your content, it's saving me right now! Small point, but I learned that an indication for beta blockers in heart failure is to offset the ongoing effects of sympathetic activation in CHF. Obviously the sympathetic effects are good in acute settings, but in chronic settings the sympathetics are part of what leads to the pathophys of chronic CHF. I feel like that fills in a gap when you discuss indications!
The ongoing compensation via autonomics can (paradoxically) lead to decompensation via physiologic/structural changes, but once the patient is decompensated you don't want to interfere with the autonomic compensation response because it is too little too late.
You made my studying a very comprehensive one! I cant thank you enough! I'm taking my NCLEX soon and you are a huge help!
I am preparing for Nclex and studying here to make my concepts clear … thankyou for clearing concepts
I absolutely love this channel. It's the only thing keeping me sane through FNP school. I may have listened to "double block that AV node" a few too many times but it helped me remember not to give beta blockers and calcium channel blockers together!
No one in this world is a better teacher than you 😘jst jst brilliant way of teaching 💪👌 love you ninja nerd😘❣️
There is no teacher greater than you I'm sure ... Thank you so much
I’m an Italian md, this is the best channel i ever watched. Amazing job! 🙌🙌🙏🙏
You are Number one teacher ever well-done DOC
this guy makes we want to study harder
Very very clear explanation from the start up to the last part Sir!!!
I am addicted to your videos Please upload more pharmacology lectures 💕
explaining complex concept in very simple way,fantastic.
idk if you'll ever read this comment but you my friend are a savior for all of us medical students.
You are the very best. Occasionally, when going over important concepts, it might be best to slow down a bit on the speed of your speech. Because you are so familiar and well versed in the subject, I can understand why you feel the need for speed in order to cover the subject completely in the short amount of time you have. Nonetheless, you are the VERY BEST lecturer I have ever encountered in my life.
Some Ninja Nerds who have had issues with Zach's speed have reported setting the playback speed to x0.75 helps them! It's hard to contain his exuberance sometimes!
I can't thank you enough for these high quality videos you all produce!!
Unbelievable how good your lectures are!!! Thank you so much ❤️
This guy's videos are blessings in disguise ;)
This is a legacy u leaving behind, we really appreciate ur lecture
I whish I had found you earlier than 1 day before my exam, thank you still. It's so much clearer now !
No one can explain any topic like u do 👌👌👌👌👌
First RUclips comment, thank you for all your lectures you are absolutely amazing. All health professionals and future health professionals continue to benefit from your astounding lectures. I love your content- thank you x1,0000,00000
hey really greart vids im thinking about to show them to my profs and they would see how online classes could be actually good
Yes your teaching and clear concept make us rich. Thank you.
Your are inspiration to teach and can integrated among draw and explain very cleary...
You are such an amazing teacher, everything just makes sense after listening to your lectures, keeep up the great work
Beautiful fact he enjoys teaching ......lots of love to him❤️
Extremely nice and clear clarification. Tank you .
How do you study for this kind of presentation? your Method of study is behind all this powerful, simple presentation. I just begin my Pharmacology 1 at PNG Uni of Med & Health Sciences. Thank you for lifetime proff
Best teacher in the world ,Thank you so much ❤️
Thank you for the awesome overview. The labeling of the funny Na++ channel inside the pacemaker cell is "Ca++" (should be Na++) - around minute 23, 24 in the video.
This is one of your hardest videos ive seen so far.
thankyou for the beautiful explanation.
please make videos on every topic of pharmacology, microbiology.
The best of the best lecture. Gold standard 👏🏼👏🏼
Love how you explain things and it makes sense
You explain better than all of my university professors 😅thank you so much
I'm not a Med student but I love your presentations. I am a retired electronic engineer and now believe the human race runs on cellular MilliVolts levels and other chemical interactions I have yet to understand. Thanks!
I love your in depth explanation and rationale for each drugs, very informative and easy to understand. well done and keep the good work. Well recommended. Good bless and keep safe.
amazing proffesor Dr consultant u are sir
LOL, simple concept, right? I'm off to get my alcoholic beverage to act on my overstimulated brain cells. I truly appreciate how this is all broken down VISUALLY so that I can truly grasp the concepts. This is the first and only site I go to for pharm and theory. Thank you so much!
Thanks so much for simplifying this in depth topic. You made it seem so easy.
its the best cology video i have watched. want u to make more on other topics like antibiotics and CNS
YOU'RE MAKING MEDICINE FUN! THANK YOU
Hi Sir! I am wishing you a happy teachers' day in advance as you are doing a invaluable work for the mankind.God bless you Dr Zach
I want to say just a huge huge thank u ,how u prepare all the topic sooooooo welll 😊😊😊😊😊
FANTASTIC LECTURING SKILL!!!
This is just the perfect way of explaining beta blockers.
Very beneficial information to nurses thank you
Definitely the best pharmacology lecture
Learned a lot! I didn't know atenolol and metopolol were in the same generation. Great video. You explain things so well. Thank you.
Another amazing video, keep up the good work! You’re getting my whole class through pharmacy school. You deserve a shout out at our graduation. I couldn’t thank you enough.
Outstanding teaching..i m loving to see ur all videos
YOU are awesome, the greatest Ninja Nerd in the world !
Great Job! I love watching your videos! They help me a lot at med school!!
I would like to ask, if you’ve got your beta-adrenergic receptors blocked, and you want to raise your HR with atropine, which blocks the muscarinic receptors. Who’s gonna act?
My point is, if your circulating catecholamines can’t bind to their receptors (because they are inhibited by the beta-blockers), why would you give an anti-cholinergic? I mean, you would be blocking the sympathetic and parasympathetic at the same time.
I think that you should give something to displace the beta-blockers from their receptors, for example, isoprenaline.
This is all my point of view, if I’m wrong, please let me know!! Because the best way of learning is through discussing knowledge.
Anyways, I enjoy studying with your videos! You are extremely great, and you explain thousand times better than all of my med school teachers!
Hugs from Argentina 🇦🇷! Sorry for my horrible English!!!
I got prescribed propranolol for anxiety after alcohol withdrawal, and, true to form, taking them has started causing me anxiety, lol. They do work really well for reducing the sweats, shakes, tachypnea and tachycardia, but they don't directly impact the mental aspect- one could even say that they approach anxiety from the other direction that benzos do. Benzos calm the brain, which calms the body, Inderal calms the body, which allows the mind to calm down. So now I'm watching videos like this one, so I can calm my hypochondriac ass down further, lmao. It's helping, too, so thanks. I'll dazzle my doctor with my knowledge during our next visit.
Keep going man, you are brilliant. You helped me a lot to prepare my final tests.
subscribed! it would be worth it to watch your videos, things are logically explained and make so much sense
Much impressive lecture.
Keep ur efforts continue. ❤
Amazing knowledge and teaching technique!!!
nice sir amazing method of teaching please continuos sir pharmacology especially cardiovascular system pharmacology
I freaking love you, guys, can't thank you enough ❤
More pharma please dr zach we need videos of analgesics and Local Ansthesia and many moreeee
also please continue the microbiology series
general medicine
General surgery topics will be appreciated
Thank you for the explanation and the effort that you put in your videos
Love this lecture
i really can't thank you enough man thanks for all the hard work u r putting in this channel and for your efforts god bless and keep up the hard work :D
Oh my god, he is an amazing RUclipsr I have ever seen 💕😍
I like the way you explained it, better then my professor 😂
haha... agree
A friend closed to me have used also this t.co/GsO1JmyXtf
high blood pressure treatment I stumbled upon on His blood pressure levels was stroke level 158/120. The result of the program can be seen right away especially if you eat the proper foodstuff. Right after Two weeks, he has seen a gradual decrease in his high blood pressure to 128/84.
This dude is amazing. 💯💯💯Thank you!
Trying Propranolol for migraine prevention (day three so far). I also have extrne levels of generalized anxiety and slightly high blood pressure. Week long migraine gone as of yesterday. No negative side effects so far.
Great job!!! love your all your lectures.
Intriguing. My BP before propanol was high with migraines and anxiety. Now my BP is either still high or super low. My thinking is leaning to me to Pheochromocytoma.
Awesome!!! Zach master is excellent!
my love for zach is going out of the roof
Ninja Nerd you are the best! At first I found the topic hard to connect in such systematic way, but you made my day a lot easier. Are you MD? Resident? What kind of qualification do you have?
I've just been diagnosed with SVT. I currently have DVT, PE, COPD-2, PAD and CAD.
Checking what side effects Beta Blockers have. General, instead of being bedridden or close to it. I'm now going to be able to slow my tachycardia but now loose more quality of life due to diarrhea, increased edema, vision problems (had Glaucoma since 2000),...
It seems the best move now is to purchase a 38' because I will never have any quality of life ever again.
My entire family is gone, what friends I had are no more. I live in a van with the minimalist of life's aids with no Healthcare luxuries.
From what I could understand and learn, the Second Generation might help...but again, too many negative side effects especially living alone.
Praying doesn't work anymore.
Hoping for your recovery and stay strong. Being alone can be tough especially with health problems but I pray you find the will to push through!
You are a life saver !!! keep making more videos
Thanks , very clear explanation 😊
Need more videos on alpha and beta agonist drugs 🙏🙏🙏
I take carvedilol and lisinopril for high blood pressure. I have mild diastolic dysfunction and mild aorta widening as well as long QT Syndrome. I love your videos and indepth explainations!
Awesome - and thanks for your time and effort.
Great video - very informative! I am confused on the effect of sympathetic stimulation on beta cells of the blood vessels in the video (8:05). I think it causes vasoconstriction, but in the video you said it is vasodilation which supports increase in BP too. Am I missing something? 😬
blood vessels have different types of receptors (alpha 1 & beta 2...) which are localised as so:
alpha 1 are localised in arterioles all over the body expect coronary arteries and vessels that supply the CNS ,which have beta 2 receptors...so that when you have an activation of sympathetic nervous system or you are on shock the vasoconstriction does not affect the vessels supplying the brain and the heart thus maintaining their function....
(I guess)