Calcium Channel Blockers | Mechanism of Action, Indications, Adverse Reactions, Contraindications

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  • Опубликовано: 14 апр 2020
  • Official Ninja Nerd Website: ninjanerd.org
    Ninja Nerds!
    During this lecture Professor Zach Murphy will go into detail on how Calcium Channel Blockers are used to lower and control high blood pressure. This will include a brief discussion on the pathophysiology of hypertension (HTN) and how Calcium Channel Blockers target specific receptors to ultimately lower and control high blood pressure. We will then discuss the indications, adverse drug reactions, and contraindications for Calcium Channel Blockers.
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    #ninjanerd #CalciumChannelBlockers #Antihypertensives

Комментарии • 165

  • @shahabalam3348
    @shahabalam3348 2 года назад +24

    You deserve awards for teaching so nicely and amazingly ❤️

  • @Rvns556
    @Rvns556 3 года назад +13

    10:30 that giggle when you know something is very complex in medicine but you just love it so much.
    Truly Nerding Out.

  • @TheOneAngelina
    @TheOneAngelina 3 года назад +10

    Thank you! I have a Medicinal chemistry/pharmacology exam on Acei/ARBs/CCBs, RAAS, diuretics, vasodilators, sympatholytics, and dyslipidemia coming up and your videos are EXCELLENT supplementation to the lecture materials I have. I LOVE watching your videos after each lecture to really get a visual of what's going on. Keep doing what you do! Thanks guys!

  • @neelhinsu7971
    @neelhinsu7971 4 года назад +38

    Please!! Make some more videos on pharmacology. It's a heartly request to you 🙏🙏😥

  • @toyajohnson7221
    @toyajohnson7221 3 года назад +6

    That was amazing!!! I love the way you break it down so easily.....I really understand it now and I’m excited about that. Thank you so much!

  • @brianwilkerson2513
    @brianwilkerson2513 4 года назад +4

    Love the videos about med. These are amazingly helpful for advanced pharmacology. Thank you for making these.

  • @_ms.b_
    @_ms.b_ Год назад +1

    Omg. You are so great. Thank you. Just started amlodipine. Ankle starting to swell.

  • @architasaha8917
    @architasaha8917 4 года назад

    You explained it in such a interesting and easy way, very much grateful to you. Thanks a lot.

  • @TLKK2020
    @TLKK2020 4 года назад +4

    I also just shared with my entire nursing school!!! Hope it gets you guys many more views you deserve it!

  • @pedropedretti2071
    @pedropedretti2071 2 года назад +1

    Your classes are extremely helpful. Much thanks!!

  • @alejandrasaucedo7035
    @alejandrasaucedo7035 4 года назад +5

    i was a nursing student (LPN) when i discovered your channel , you made my nursing journey so much easier and for that i’m eternally grateful ... i want to see you around while i do my LVN to RN program ... don’t go anywhere !

  • @muskandeshwal9299
    @muskandeshwal9299 3 года назад +2

    A big big thankyou from all my heart......i wish you success ......hope you grow and reach the skies.....❤️❤️

  • @kellyann4421
    @kellyann4421 3 года назад +31

    "Make it thiccc" "That gut aint gunn work" LOL you're awesome

  • @deborahbollyn897
    @deborahbollyn897 Год назад +1

    Thanks you so much for your GREAT lectures! 👏🏼🤓👌🏼
    I have Prinzmetal’s angina a.k.a. coronary artery spasm a.k.a. CAS.
    Also referred to as ANOCA or INOCA and worse case MINOCA.
    After a Non-STEMI last year, I finally got diagnosed and since then I learned a lot from you.
    Thank you very much! 🙏🏼

  • @griselgaspar6904
    @griselgaspar6904 3 года назад +12

    You did it again Zach!! Thank you so much for all you do!

  • @ariyotolulope1360
    @ariyotolulope1360 4 года назад +3

    Your videos are always wonderful. I which in no time you cover other aspects of pharmacology eg CNS,respiratory, endocrinology etc. Thanks alot

  • @i-wei5328
    @i-wei5328 Год назад

    Beautifully explained. Thank you Professor

  • @sydneylimarez2816
    @sydneylimarez2816 Год назад

    Thank you! You're a life saver for medical student like me

  • @mapenzihamoomba8749
    @mapenzihamoomba8749 3 года назад

    Always enjoy these videos on pharmacology😃🙌

  • @jehansharif8414
    @jehansharif8414 4 года назад

    Really outstanding and great lecture
    Plz keep it up fore more lecs

  • @marielouise966
    @marielouise966 2 года назад +4

    im so glad that i found this lecture Ninja Nerd, since i take calcium channel blocker Lercanidipin which you didn't mention but can i assume is also acting like the other *dipines ? i have a low serum calcium and one thing i would like to know is if taking a calcium channel blocker has any affect on serum calcium levels ?

  • @mariamhussien6303
    @mariamhussien6303 4 года назад +4

    Thank you 💞 best RUclips channel ever

  • @simgarfu
    @simgarfu 3 года назад

    Amazing stuff! I wish I had this during my NSG studying lol.

  • @JohnMushitu
    @JohnMushitu 4 года назад +2

    Very helpful 🙌🏾 You simply the best 💪🏾

  • @niazwali8169
    @niazwali8169 4 года назад

    thank u so much sir i really become very happy when i saw ur vedios continous sir cardiovascular pharmacology

  • @SirViving
    @SirViving 3 месяца назад

    You explained it so well 👍🏻

  • @bhagat3328
    @bhagat3328 3 года назад

    Thank you so much for making it easier for us

  • @vsrump
    @vsrump 2 года назад

    ⭐️⭐️⭐️⭐️⭐️fabulous !!!even gives the “antidote” at the end 👍

  • @robertscouten8389
    @robertscouten8389 2 года назад

    Bravo! Continued excellent teaching!

  • @RAAGECAGE
    @RAAGECAGE 3 года назад +4

    Love the videos as a quick review! If possible, it would be nice if you could use different colors when drawing arrows for increases or decreases in mechanisms

  • @studysongz19
    @studysongz19 4 года назад

    Awesome video! Another great one! Just dropped a skull anatomy song yesterday.

  • @SonamSherpa-ye3nf
    @SonamSherpa-ye3nf Год назад

    Super simplified lecture thank you soo musch

  • @fredericolc6016
    @fredericolc6016 4 года назад

    Great lesson!

  • @marianamutuku6896
    @marianamutuku6896 5 месяцев назад +3

    Here in 2024. Really helpful 😊.

  • @gk_filer
    @gk_filer 3 месяца назад

    I hope they pay you well. Amazing recall of complex concepts.

  • @msieurdaveyray5393
    @msieurdaveyray5393 2 года назад

    Great tutorial, thanks.

  • @ahmadmusawer9392
    @ahmadmusawer9392 4 года назад +1

    Man, you're TOP NOTCH.

  • @talhaiqbal1660
    @talhaiqbal1660 2 года назад

    Good job big brother...
    Superb presentation
    From India

  • @afsheenilyas7532
    @afsheenilyas7532 3 года назад

    I first time understanding the pharma so well..🤩

  • @mohammads.jefferson7295
    @mohammads.jefferson7295 4 года назад

    your vids make learning fun

  • @lukefarrelly724
    @lukefarrelly724 Год назад

    Thanks man i really understand them now

  • @user-dn8fk3mw8i
    @user-dn8fk3mw8i Год назад

    Thank you very much doctor ❤️

  • @sebastianflorezmed
    @sebastianflorezmed Год назад

    I swear that I will give you my first pay as a doctor. Thank you so much Zach

  • @cathum
    @cathum 4 года назад

    Well done - thank you

  • @mukilvendhan9567
    @mukilvendhan9567 2 года назад

    Thank you sir. Best of the best sir.

  • @Harir_vision_life
    @Harir_vision_life 2 года назад +1

    Sir you are amazing... thank you so much

  • @mingukkie4746
    @mingukkie4746 9 месяцев назад +1

    you deserve a nobel prize

  • @greenottri1783
    @greenottri1783 4 года назад

    Thank you Zack

  • @aditiadvilkar2000
    @aditiadvilkar2000 4 года назад +7

    The pain from cluster headaches is caused by the dilation, or widening, of the blood vessels that supply blood to your brain and face. This dilation applies pressure to the trigeminal nerve, which transmits sensations from the face to the brain. If that is the case, how do the calcium channel blockers help in relieving the cluster headaches since they cause vasodilation?

  • @TLKK2020
    @TLKK2020 4 года назад

    Donation just sent thank you!!!

  • @sujatakumari8052
    @sujatakumari8052 4 года назад

    Amazing video thank u....... zach

  • @Joy-y31
    @Joy-y31 Год назад

    Beautiful, I got tons of useful information.

  • @cnik3313
    @cnik3313 2 года назад

    great video as always!!!! Question: what would happen if you gave a calcium channel blocker to a patient with a junctional tachycardia rhythm? Is that a bad idea?

  • @naomifavor2887
    @naomifavor2887 3 года назад

    Pretty cool,it's making sense now

  • @twesigyemayres2901
    @twesigyemayres2901 3 года назад

    U are the best teacher

  • @nilkiani7334
    @nilkiani7334 4 года назад

    Well done🤓👏🏼that’s amazing

  • @torithomas2304
    @torithomas2304 2 года назад +2

    I watch your videos as if they were a Netflix series.

  • @diannemariecalla9954
    @diannemariecalla9954 2 года назад

    Thank you, Sir

  • @toric2719
    @toric2719 2 года назад

    this is so great

  • @mohamedelmi4172
    @mohamedelmi4172 Год назад

    Thanks for refreshing.

  • @thantthuhain1688
    @thantthuhain1688 Год назад

    Thank You very much.

  • @samuelwestphal2336
    @samuelwestphal2336 4 года назад

    Amazing!

  • @saadomoula2153
    @saadomoula2153 3 года назад

    thank you so much you are the best one

  • @kirubelimalk5569
    @kirubelimalk5569 3 года назад +4

    Its amazing video. when ever i got questions or misunderstanding while studying, watching ur videos comes to mind first. I really appreciate the way you describe. keep it up please. am my question is, it might look silly but in calcium channel blocker video how constipation results as side effect? i mean i don't understand how CCBS decrease GI motility

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  3 года назад +5

      Calcium is needed in smooth muscles to cause smooth muscle contraction. If you block calcium entry you block smooth muscle contraction

    • @ambissaintek5778
      @ambissaintek5778 2 года назад

      can i ask some question? CCB is calcium channel blocker to vasodilate, but how can the calcium for lower blood pressure in some journal?

    • @tubaumer6356
      @tubaumer6356 8 месяцев назад

      ​@@ambissaintek5778by decreasing contractility when contractility decrease sv decrease co decrease and hence systolic blood pressure decrease

  • @mylvalopes6045
    @mylvalopes6045 3 года назад

    You are my hero!

  • @shahiramohammadi7284
    @shahiramohammadi7284 3 года назад

    Like always great

  • @zeevberar1663
    @zeevberar1663 4 года назад +1

    amazing THANKS
    TEL AVIV

  • @fatfar8224
    @fatfar8224 4 года назад

    That's great thanks

  • @NDtoker
    @NDtoker 4 года назад

    could you do a video on which class of antiaarythmics to use for certain things. example my dad.is on flecanide for afib and.most patients at my hospital are put on diltalzam and only reason i can find is physcian preference

  • @perceptioniseverything648
    @perceptioniseverything648 Год назад

    Thank you for this. Currently on verapamil which one would you suggest to help dilate the left side jugular vein valve. That is the issue of my disease. Thank you very much

  • @dhanushkalakmal7652
    @dhanushkalakmal7652 6 месяцев назад

    Thank u so much ❤🎉

  • @ayedqahtani5628
    @ayedqahtani5628 4 года назад

    Thank you

  • @kefesomuvie3350
    @kefesomuvie3350 3 года назад

    you are amazing!!!

  • @paracletus3166
    @paracletus3166 2 года назад +1

    25:41 😂
    Man you are amazing

  • @achalakp705
    @achalakp705 4 месяца назад

    Big thanks ♥️

  • @ruwanichathurika8840
    @ruwanichathurika8840 3 года назад

    super teaching

  • @istreamkerala1
    @istreamkerala1 2 года назад

    Awesome ❤️❤️❤️

  • @cassieconroy2576
    @cassieconroy2576 3 года назад

    you're amazing!

  • @kellyjellyxoxo
    @kellyjellyxoxo 2 года назад +1

    Hey, can you please clarify why BBs (that dec contractility, rate and vasodialate) are ok in HF but CCBs (that do the same) are not?

  • @Esther.Umoren
    @Esther.Umoren 2 месяца назад

    I love the part he said “ that gut ain’t gonna work”😂

  • @youssefrefaat1594
    @youssefrefaat1594 4 года назад +3

    can you make a video on anti-arrhythmic drugs?

  • @allymusto1130
    @allymusto1130 2 года назад +1

    What are your thoughts on taking D3 and K2 while being prescribed Amlodipine 2.5 mg?

  • @TLKK2020
    @TLKK2020 4 года назад

    I’ll donate more once I get more money!!

  • @Dr.SachinAJoshi
    @Dr.SachinAJoshi 4 года назад +1

    Hi. Instead of doing so means giving Calcium with these drugs, can we give Calcium at the first step along with Vitamin D3 and K2 to flow the calcium in cells and NATURALLY MAINTAIN THE HYPERTENSION?? Please suggest.

  • @user-iu1hp2xr3h
    @user-iu1hp2xr3h 2 года назад

    You are my hero

  • @a30s
    @a30s 4 года назад

    please make a video on larynx and pharynx in detail

  • @nicolecoyle4750
    @nicolecoyle4750 Год назад

    oh my >>> you're amazing thank you!!!!!

  • @fawziehsharabati7302
    @fawziehsharabati7302 2 года назад

    You are great 💕💕💕

  • @muttakimmahmud5385
    @muttakimmahmud5385 3 года назад

    Please make a video about centrally acting antihypertensive drugs.

  • @kellyramirez744
    @kellyramirez744 3 года назад

    Can you clarify the fact that nifedipine is said to actually increase HR since it is dihydropyridine and diltiazem is a Non-dihydropyridine

  • @anilkumarjangbahadu229
    @anilkumarjangbahadu229 3 года назад

    Sir can I use metoprolol with amlodipine to control bp and supraventricular tachycardia

  • @thebackbenchers8786
    @thebackbenchers8786 3 года назад

    i want that collection of markers one day...

  • @azorakai4428
    @azorakai4428 4 года назад

    Smart PA!

  • @rnoqks
    @rnoqks 4 года назад

    in patient with emergancy hypertension. why the Drugs is dihydrpyridine and not verampil or nondihydrodipine? they affects on Heart dirct why we used Drug affect on smoothmuscles?

  • @cumarcalicumar8299
    @cumarcalicumar8299 2 года назад

    thanks sir

  • @ravindersingh-pu4jp
    @ravindersingh-pu4jp 4 года назад

    U r awesome bro

  • @twang2884
    @twang2884 4 года назад +2

    Hey ninja need, I have a question regarding non-dihyro and dihydro. U said non dihydro slow the HR as well as contractility of heart, dihyro only affect vascular dilation. My question is: does dihydro only affect vascular system or they also affect the heart contractility? Because when I listen to ur lecture, when u talked about what indication for both type CCB, I was bit confused. Thank you

    • @sharonsililo7663
      @sharonsililo7663 4 года назад +2

      Dihydros eg Amlodipine ,primarily work on the vascular system.. In my own understanding, I think they also have an effect on the heart but not to significant amounts. Hence, they are very useful in isolated diastolic hypertension and NOT isolated systolic hypertension..
      I don't know if you get my point though

  • @quratulainadnan1162
    @quratulainadnan1162 Год назад

    Amazingggg vdo

  • @muhammadjunaidali4007
    @muhammadjunaidali4007 4 года назад

    Awesome

  • @OmarAli-py3pq
    @OmarAli-py3pq 3 года назад

    Awesome 🤩 🦋🦋🦋🦋