Vasopressors: Inodilators, Inopressors, Pure Vasopressors, Methylene Blue, Midodrine

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  • Опубликовано: 27 июл 2024
  • Official Ninja Nerd Website: ninjanerd.org
    You can find the NOTES and ILLUSTRATIONS for this lecture on our website at: www.ninjanerd.org/lecture/vas...
    Ninja Nerds!
    In this lecture Professor Zach Murphy will be presenting on Vasopressors. We start this lecture by talking about the most common types of Inodilators including the indications, titration parameters, and advantages/disadvantages for Dobutamine, Milrinone, and Isoproterenol. The next category of Vasopressors we discuss is Inopressors. We will be discussing the indications, titration parameters, and the advantages/disadvantages for Epinephrine, Norepinephrine, and Dopamine. The next category of Vasopressors we will be talking about is Pure Vasopressors to include the indications, titrations parameters, and advantages/disadvantages of Phenylephrine, Vasopressin, and Angiotensin-II. The last type of Vasopressor we will be discussing is referred to as Methylene Blue, which will include an explanation on its indications, titration parameters, and advantages/disadvantages. We will also be having a brief discussion on how vasopressors can be commonly administrated to a patient including peripheral IV and central venous catheter. Finally, this lecture is concluded with a description of Midodrine, a vasopressor that can be administrated orally along with its indications and advantages/disadvantages.
    We hope you enjoy this lecture and be sure to support us below!
    Table of Contents:
    0:00 Lab
    0:08 Vasopressors Introduction
    0:36 Inodilators - Dobutamine, Milrinone, and Isoproterenol
    23:02 Inopressors - Epinephrine, Norepinephrine, and Dopamine
    43:10 Pure Vasopressors - Phenylephrine, Vasopressin, and Angiotensin-II
    1:07:35 Methylene Blue
    1:17:13 Methods to Administrate Vasopressors
    1:22:07 Midodrine - Alternative Vasopressor
    1:25:58 Outro: As Always, Until Next Time
    1:26:06 Comment, Like, SUBSCRIBE!
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Комментарии • 84

  • @narayanprasad5244
    @narayanprasad5244 3 месяца назад +7

    Every medical school in the world should close and just have students subscribe to this channel. I am an Australian Emergency Medicine advanced trainee preparing for my Fellowship examinations and I don't know where or what I would be without you!!!

    • @Steven_DunbarSL
      @Steven_DunbarSL 2 месяца назад

      Hi, is that a position in medical school?

  • @TheGasPrincess
    @TheGasPrincess 2 года назад +9

    You and your team are literally hands down the best out there. Thank you for all your hard work and for helping us all to become better medical professionals!

  • @fionarob8371
    @fionarob8371 3 месяца назад +1

    Best video explaining vasopressors ever! I'm an ICU nurse trying to get into CRNA school and this video definitely helps a lot. Thank you for your hard work!

  • @spanish_regime_4hundred363
    @spanish_regime_4hundred363 2 года назад +31

    Wonderful! Can you also pls talk about Impella and intra-aortic balloon pump? Thank you, Professor Zach.

  • @lilanli5993
    @lilanli5993 Месяц назад +1

    So addicted to watching your videos everyday

  • @JorgeLuiz-qn3is
    @JorgeLuiz-qn3is Год назад +2

    I'm from Brazil and i just wanna thank you for everything you do for people who whants to learn. Amazing man! Best regards!

  • @snugglynuts
    @snugglynuts Год назад +4

    I work in the CVICU and this video has been super helpful in learning about the various cardiac meds. Big ups homie

  • @ricardocampbell8929
    @ricardocampbell8929 5 месяцев назад +1

    I am currently studying for my CCRN test, and this video was very helpful in explaining the mechanism of action for some common medications seen in the test. Thank you and your team for putting this together!

  • @shahiramohammadi7284
    @shahiramohammadi7284 2 года назад +4

    I don't know how to thank you Zach you are so great👏🏻

  • @michelleduane8841
    @michelleduane8841 2 года назад +2

    Wow! You love teaching and it shows. Ty for this great lecture. Awesome!!

  • @Vanessamichelle84
    @Vanessamichelle84 Год назад +2

    love your enthusiasm in teaching, you keep my attention and make me enjoy learning!

  • @philorida
    @philorida 2 месяца назад

    I'm enjoying your presentations. Not a wasted breath.

  • @michaelbraccia4556
    @michaelbraccia4556 2 года назад +3

    GREAT LECTURE THANK YOU

  • @subashthapa8066
    @subashthapa8066 2 года назад +5

    I really enjoyed this lecture and learned so many things that would have taken me days to grasp from books...your style and presentation are both awesome and concise. Thank you

  • @darleen6258
    @darleen6258 2 года назад +3

    You are agreat Dr.
    You are the Best.
    Thank you very much

  • @ashnadesai6292
    @ashnadesai6292 2 года назад +2

    This helped me so much! Thankyou

  • @time2go465
    @time2go465 2 года назад +4

    This is so awesome from ninja nerd and Prof Zach , my cardiovascular disease exam is on next Friday and this and atrial fibrillation video just dropped right in time for my further understanding and revision 😄

  • @aimz5479
    @aimz5479 2 года назад +2

    the best professor thank u for saving lives

  • @hibakamran3554
    @hibakamran3554 2 года назад

    thanks a million and zillions DR. zach you're a blessing :)

  • @newmanlord7130
    @newmanlord7130 2 года назад

    I am getting the window of Vasopressor significantly from You Doc,
    This is Great Video Prof.
    Hi from Ghana.

  • @yusrahassan2363
    @yusrahassan2363 2 года назад

    you made this topic a piece of cake. thank u

  • @mayamaan1
    @mayamaan1 2 года назад

    Please continue giving back to the Universe…The Universe will give it back to you. You have helped so many of us. I am getting ready to transition to a critical care and your lecture is valuable to my growth.

  • @CaseyRoff
    @CaseyRoff 3 месяца назад

    Incredible video guys! I feel like a lot of learning these things is spaced repetition, contextualisation and seeing the same topic presented in different ways. You do such an fantastic job with these drugs, especially the ones that act on multiple systems. The way you repeat the MOA is seriously great teaching, it makes me understand the principles so that by remembering something like, phenylephrine has strong alpha activity and mild beta activity, you can predict it's effect and side effects. Love it

  • @lucianaguerra8367
    @lucianaguerra8367 2 года назад

    Great lesson !

  • @sweetgabaruby
    @sweetgabaruby Год назад +1

    This video is very very good, I'm new to ICU, can you do a video on the medications use for intubation and why they choose them. Analgesic, paralytic, nerve blocking agents.
    Thank you

  • @michaelmuller136
    @michaelmuller136 Год назад

    Yeah, finished the Cardiovascular Pharmacology Playlist, that was interesting, thank you!

  • @driftinxer
    @driftinxer 2 года назад +4

    thank you master 👍

  • @rahuldas-sc8vs
    @rahuldas-sc8vs Год назад

    Brilliant teaching Sir

  • @medicalbiochemistry_
    @medicalbiochemistry_ 2 года назад +1

    Simply the best

  • @RUYINAETENGsMEDICDIARY
    @RUYINAETENGsMEDICDIARY 2 года назад +1

    Well done!

  • @user-ym7fx9kc2b
    @user-ym7fx9kc2b 2 года назад +2

    make more videos please am clinical pharmacy student your lecture is fantastic

  • @darleen6258
    @darleen6258 Год назад

    Perfect. Thank you very much ❤

  • @erinseawright9829
    @erinseawright9829 2 года назад +1

    This dropped at the perfect time for my med school curriculum😭👏

  • @gustavs495
    @gustavs495 2 года назад

    Thanks prof God bless you

  • @borrah1281
    @borrah1281 2 года назад

    the best as always

  • @Alan-wl5de
    @Alan-wl5de Год назад

    I love you. i am a pharmacist, the best lecture, ever. thank you

  • @judyjimenez9506
    @judyjimenez9506 2 года назад

    Yes … plz discuss Impella device, screen device , parameter , care of patient , risks and benefits … :)

  • @theshapedexperience
    @theshapedexperience 3 месяца назад

    thank you for this!

  • @aliholguin
    @aliholguin 8 месяцев назад

    Amazing. Thank you

  • @sonamdhondup5426
    @sonamdhondup5426 9 месяцев назад

    Thank you for the great video

  • @rebeccasauer9191
    @rebeccasauer9191 10 месяцев назад

    Excellent!

  • @LoanTran-hi1po
    @LoanTran-hi1po 2 года назад +3

    What an awesome lecture!!!!

  • @brunoteneos
    @brunoteneos 7 месяцев назад

    You're awesome!! Can't thank you enough

  • @ambiakhatunmehediimransumi7474
    @ambiakhatunmehediimransumi7474 2 года назад

    the legend ZACH sir

  • @DoctorOck1254
    @DoctorOck1254 2 года назад

    Can you make a lecture about immunosuppressive drugs, your explanation helps me a lot

  • @futuretimes805
    @futuretimes805 2 года назад

    Legendary zach

  • @parmindermann7876
    @parmindermann7876 6 месяцев назад

    So knowledgeable 👏👏👏

  • @user-wm7iu1yb1l
    @user-wm7iu1yb1l 10 месяцев назад

    Wow interesting lectures

  • @DoccOtt
    @DoccOtt 2 года назад +1

    Hey! Big fan! Really love the videos and how you make absurdly complex subjects so simple and easy to understand.
    Ive got three questions.
    #1 I get regularly scolded for saying dopamine is dose dependent. As i understand, internists say that dopamine’s dose dependant title was no longer accurate (according to some recent studies). Again, this probably has low impact on a patient that has already exhausted all other options, but why is this particular drug still named as an option if these potential side effects and overall effectivenes are this extremeis?
    #2. Based strictly on its mechanism on action and physiological response, should Levosimendan be considered as a possible inotrope?
    3. In a cardiogenic shock context (purely from an ischemic etiology) , wouldnt chronotropes and vasopressors induce higher myocardial oxygen consumption leading to a higher degree of tissue damage?
    Thank you!

    • @MultiNerve
      @MultiNerve Год назад

      I can only answer #3, which is - yes. They are known for being bad if you put them in a peripheral IV. Levophed can cause someone to look like they're going through SJS/TEN if you have to push it through a PIV. It will cause massive sloughing of the skin around the PIV site

  • @formynation
    @formynation Год назад +1

    No doubt a legend u are❤

  • @oabouassy
    @oabouassy 2 года назад

    Excuse me guys , in which order should I study physiology playlists in this wonderful channel ?

  • @theferaltaint5065
    @theferaltaint5065 Год назад

    Great one Zach. As for AT-II, I’m with you. As a nurse, it would be very hard for me to advocate for such a drug in any critically ill patient. Especially if they are intubated and/or have any potentially worsening pulmonary pathology. Excess ACE-II can lead to micro and macro vascular endothelial dysfunction. This could potentially worsen any underlying SIRS response, contribute to a pro-coagulopathic state, etc. All of which could contribute to the development of ARDS, DIC, worsening vasoplegia, increased vascular permeability, etc. etc. etc. It just seems like an unnecessary risk to take when we have better options.

    • @theferaltaint5065
      @theferaltaint5065 Год назад

      Lol and just as I finish typing my comment, you basically point all of that out. 😅

  • @zia735
    @zia735 2 года назад +1

    King in medical sciences

  • @Mina-Rofaeil
    @Mina-Rofaeil 2 года назад

    Please add Heparin's notes and illustration on the website.

  • @Demothones
    @Demothones 2 года назад

    My understanding is that MAP of 65 is for when you don’t know your patient’s baseline. If you do know your pop patient’s baseline then the goal should be +\- 20% of baseline. Is that correct?

  • @lillianotuokwu5800
    @lillianotuokwu5800 2 года назад

    great❤

  • @darleen6258
    @darleen6258 2 года назад

    Please talk about Ischemic Heart disease

  • @dawnsmith370
    @dawnsmith370 Год назад

    I am researching this now and any comments appreciated. I am 59 female and only known problems is my recent bloodwork shows my RBC steadily climbing and now flagged high and my hemotocrit and hemoglobin has been flagged high for 8 years. Dr is wanting me to go for a sleep study next week something about oxygen🤷‍♀️. Also I have to get a thyroid ultrasound annually , it is enlarged and nodules that needs monitored and I have 2 doctors fighting over whether to take it out •. I prefer to keep my organs and no prescription meds.

  • @jerlinnadar1581
    @jerlinnadar1581 2 года назад

    Need more video in pharmacology 🙏 plz

  • @josephryan3707
    @josephryan3707 8 месяцев назад

    I watched all of your videos when I was taking anatomy courses and then tutoring anatomy. Now I watch your videos to help me be a good nurse in the ICU. Thank you

  • @LilFella67
    @LilFella67 Год назад

    @Ninja Nerd
    Never used the blue infusion at my institution. Will the methylene blue infusion turn the patient blue after 1-3 days?

  • @sorrymudabbir1659
    @sorrymudabbir1659 2 года назад

    how does vasopressors dilates pulonary arteries??

  • @drabdirahmanibrahin6021
    @drabdirahmanibrahin6021 2 года назад +1

    Thank uuuuuuuuuuuuuuuuuuuuuu

  • @ishalmydream1786
    @ishalmydream1786 4 месяца назад

    Super

  • @markdavid4897
    @markdavid4897 Год назад

    Methylene Blue fixes many things inside the human body. Are the blood pressure increases caused by taking MB cause for alarm? Cellular respiration is improved with MB, so does one offset the other in terms of oxygen delivery? It would seem that MB would overall be a positive for the patient in most cases.

  • @JC-xk8vh
    @JC-xk8vh 2 года назад

    @16:46 What do you mean never titrate against BP? Meaning use them as a monotherapy just to combat low BP? Can you please clarify? I am confused. TIA

  • @archiemercado4289
    @archiemercado4289 Год назад +1

    40/dead got me. LOLOL

  • @paulmtae1738
    @paulmtae1738 2 года назад

    Please Sir can you make a video on MYOCARDIAL INFARCTION please

  • @hewhoknocks2880
    @hewhoknocks2880 5 месяцев назад

    Man are you a cardiologist ?
    If so where ! I will travel the country to be your patient
    Let me know please
    I’m in Miami

  • @gayatrick2248
    @gayatrick2248 11 месяцев назад

    I've a doubt regarding methylene blue

  • @RealJonzuk
    @RealJonzuk Год назад

    I wish salvia divinorum was studied for heart effects

  • @purushottamparajuli842
    @purushottamparajuli842 2 года назад

    👍👍

  • @mrusurped5597
    @mrusurped5597 2 года назад +1

    I love u

  • @sirenasirian4036
    @sirenasirian4036 2 года назад

    🌹🌹🌹❤️❤️❤️

  • @matt360360
    @matt360360 Год назад

    You lost me at hello. 😅

  • @stevemitz4740
    @stevemitz4740 2 года назад

    I don't understand what stimulates or drives one to put silly ink "art"/ graffiti on a God designed body! It reminds me of walls in the black ghettos, marked up with "cool" crap art!

  • @Dolofonix
    @Dolofonix Год назад

    Perfect. Thank you very much ❤