Large-scale single neuron encoding of speech sounds across the depth of human cortex

Researchers in the lab of Edward Chang, MD, at UCSF recorded activity from hundreds of individual neurons across all layers of the cortex while participants listened to spoken sentences. In a study published in Nature on December 13, 2023, the researchers showed that neurons responded to different speech sounds like parts of consonants and vowels, or the pitch of the voice. This work provides the most detailed picture yet of how the human brain processes speech.
Matthew K. Leonard, Laura Gwilliams, Kristin K. Sellers, Jason E. Chung, Duo Xu, Gavin Mischler, Nima Mesgarani, Marleen Welkenhuysen, Barundeb Dutta, Edward F. Chang. Large-scale single neuron encoding of speech sounds across the depth of human cortex. Nature. DOI: doi.org/10.103...
Narrated by Terri Scott, PhD.
Illustrations/Animation by Ken Probst
Video Editing: Todd Dubnicoff, PhD