The Big DEMENTIA risk of D-Ribose? Pros and Cons of the Supplement
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- Опубликовано: 1 окт 2024
- Myalgic Encephalomyelitis / Chronic Fatigue Syndrome. This video is also relevant for Long Covid and POTS.
My name is Patrick Ussher and I am an ME/CFS patient. I have written a book on POTS and also about thirst in ME/CFS, POTS and Long Covid.
Personal website (including details about consultations service): www.patrickussher.com
My (free) book on thirst in ME/CFS, POTS, LC: www.themythofprimarypolydipsia.com
NB: This video is for educational purposes only - please always consult a doctor about any health issues or changes.
Links mentioned in this video:
Normalyte (most helpful supplement I've ever found for ME/CFS) - affiliate link: normalyte.com/...
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This meta-analysis actually found that ribose was likely safe at up to 1g/kg/day for mice which is about 80mg/kg/day for humans which is 2.5x more than the max safe dose for humans according to European FSA.
I would say if it makes you feel healthy then keep taking it. If it will cause memory problems you should notice them within weeks.
Thanks very much for sharing that.
Just trying to work out the maths of it.....
I'm 70 kg. 80 mg x 70 = 5600mg = 5.6 grams
Most ME/CFS patients are told to have 10-15 grams daily.
As for memory problems, maybe you are right but I've no idea how long they might take to show up. My brain already is foggy enough with my chronic illness - so it can be hard to know what is causing what.
Theses days I take Ribose only as a rescue remedy.
@@me-cfs-strategiesforhealing according to Healthline, ribose has been shown safe in humans up to 60g daily. Idk why mice have an issue with it. The 36mg/kg/day limit set by EFSA was based not on NOAEL but rather just average of what people consume in their diet.
I think prob no need to worry but if you do have brain fog then you should try detoxing metals, parasites, mold, pesticides, forever chems, etc. Sniffing dmso vapors can help. High dose niacin can help. Activated charcoal ozone steam also may be excellent.
Fantastic summary, thank you for sharing. I am trying d ribose as my last resort before going back to a carnivore diet, as the diet works but I hate doing it and it has some side effects.
And thank you for the kind words!
I've actually been struggling more recently since giving up Ribose altogether so I've decided to take 5 grams a day for a while. It is making a helpful difference and, at that dosage, I think it is more likely to be okay. Hope so anyway! I'm not carnivore at the moment (was for 5 months) but hope to go back to it next month.
Hope Ribose works out for you.
Yes , men and women are the same species. However bodies are obviously different. Hormones , testosterone levels, menses etc .
Yes but the context of my remark is about Ribose specifically. I find it hard to believe that women would only produce 2 grams of Ribose daily and men 18 grams, given how crucial ribose is in creating ATP, the body's energy currency molecule. So I'm not sure that the Norwegian booklet I read can be right.
Short dry fast clear(desolve) glycated proteins in the body
Thank you for sharing.
I took D Ribose for 3 months . I felt like it helped me feel 25% better .. I stopped taking it only because I ran out and never bought any more . Now I feel like I would have to research it again .
L-Ribose is the synthetic form
Thank you for letting me know.
My regulat blood pressure is 170 over 90 sometimes higher
Get a MRI and see if anything is going on with your brain, if not...keep taking it
Pickles from the store break through the blood brain barrier read your labels!
My husband is prone to hypo glicemia and after taking this supplement a couple of times (with no remarkable effects), he had some hypo episodes so he stopped its consumption (he is an ME/CFS patient by the way). Thanks for this video
You are welcome, thanks for sharing.
Very interesting video, thank you Patrick.
I believe this could potentially help me as well, but am now thinking it might be better not even trying it, as to prevent alzheimer etc... this is a new dilemma you just presented me with! 😮
I am taking Nad+ daily, which is really called "nicotinamide riboside". So, I was worried this was the same thing as D-ribose. But when doing a quick Google search it seems to be different things but with a similar name. Nicotinamide riboside being more closer to Niacin, vit b3, while D-ribose is closer to a sugar. I just wanted to write this in case any other viewer might wonder the same thing.
Oh, I know - it is quite the dilemma! I feel great on Ribose but after 3 years on it, I just don't want to run the potential risk of ending up with something worse down the line. The joys of supplements, eh?
How do you find NAD+? I've never tried it.
@@me-cfs-strategiesforhealing I see. Yeah the joys of supplements...
I am not sure about NAD+ yet, if it helps me or not. I am only taking half a capsule per day, otherwise I have trouble falling asleep at night.
However, I really do feel that ALC is helping me (Acetyl-L-Carnitine). My mood is generally better, feel a bit happier while taking it. 400mg daily. In your case Patrick, you already eat lots of meat, so it might not make a big difference for you, but in my case (I have trouble eating red meat), it does help. I have listened to several ME doctors that are recommending this supplement to their patients.
That's great the ALC is helping you. Yes, it wouldn't make sense for me to take that or CoQ10. My CoQ10 level recently tested above range thanks to all the meat.
@@me-cfs-strategiesforhealing I am on 800mg Q10 a day... it has been a lifesaver for me.
That's great it so helpful - it is a brilliant supplement for a lot of ME/CFS people.