Hi....in the video at around 9:44 minutes you mistakenly said that Alpha2 receptors primarily located upon "Pre" synaptic nerve terminals......Whereas actually THEY SITUATE ON "POST"SYNAPTIC NERVE TERMINALS.....as you rightly showed and teach in the diagram...... (by the way superb video and I happily enjoyed learning through your videos)
Glad you liked the video and thank you for the comment! The video is correct in that Alpha-2 receptors are located on presynaptic nerve terminals. Make sure not to confuse the terms "preganglionic and postganglionic neurons" with "presynaptic and postsynaptic neurons". They're not the same thing. Remember a synapse is simply the junction. A presynaptic neuron sends information toward a synapse, and the alpha-2 receptors are located on the nerve terminal before the synapse (the presynaptic neuron). In other words, the video shows presynaptic alpha-2 receptors on the postganglionic nerve terminals. Hope that helps! 🙏🏻
I don't understand in beta 2 video u said urination decrease when smooth muscle relax...here you said when the case of alpha 1 smooth muscle of urinary system get contract.. urination will decrease Explain why?
Great question! Here is the simple answer. It's all about the location of the beta-2 and alpha-1 receptors on the bladder. The beta-2 receptors are located on the bladder wall, so when they are activated it leads to smooth muscle relaxation which will lead to decreased urination (as the bladder is not contracting). The alpha-1 receptors are located on the urethral sphincter, so when they are activated it leads to smooth muscle contraction which will cause contraction of the sphincter which will prevent urine from exiting the bladder. So we can see how alpha-1 urethral sphincter constriction combined with the beta-2 bladder wall relaxation will synergistically cause urinary retention and decreased urination. Hope that helps! 🙏🏻
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this is worth more than 3 months long lectures in Pharmacy school. Very easy to understand and nailing the key points. Thank you.
Glad to hear it 👍 Appreciate you watching
Awesome teaching, you made the receptors very very very very easy to understand. God bless you for teaching and sharing ❤❤❤❤❤
Hi....in the video at around 9:44 minutes you mistakenly said that Alpha2 receptors primarily located upon "Pre" synaptic nerve terminals......Whereas actually THEY SITUATE ON "POST"SYNAPTIC NERVE TERMINALS.....as you rightly showed and teach in the diagram...... (by the way superb video and I happily enjoyed learning through your videos)
Glad you liked the video and thank you for the comment! The video is correct in that Alpha-2 receptors are located on presynaptic nerve terminals. Make sure not to confuse the terms "preganglionic and postganglionic neurons" with "presynaptic and postsynaptic neurons". They're not the same thing. Remember a synapse is simply the junction. A presynaptic neuron sends information toward a synapse, and the alpha-2 receptors are located on the nerve terminal before the synapse (the presynaptic neuron). In other words, the video shows presynaptic alpha-2 receptors on the postganglionic nerve terminals. Hope that helps! 🙏🏻
The best explanation in youtube.
That means a lot, thanks for watching!
this was extremely helpful thank you.
Glad it was helpful!
❤ loved the description, very succinct and informative
Perfect! 👌 That was the goal, glad you liked it! 👍
this video is a hidden gem!!!
Appreciate it, thanks for the support!
superb sirr☺️ I love this learning channel 😅i lucky to choose this video 😍
Glad you like the channel! 🙌
thank you for making this receptors simple to understand
You bet! 👏 The goal of the channel is to simplify topics and glad to hear this did just that!
Stay blessed sir
What a gem, man!
Very helpful, thanks😘😘
Glad to hear it was helpful! You're welcome! 😊
oo.. genius ...absolutely genius
Haha appreciate it! 🙏🏻 Thanks for watching!
Helped alot, thank u ❤️
Great! 🙌 Appreciate you watching and commenting!
Thanks sir!
No problem!
thank you, thank you!
You're welcome! 👏
Taking an alpha 2 antagonist for my pre work out
Thankyou
You're welcome! 👏
I don't understand in beta 2 video u said urination decrease when smooth muscle relax...here you said when the case of alpha 1 smooth muscle of urinary system get contract.. urination will decrease
Explain why?
Great question! Here is the simple answer. It's all about the location of the beta-2 and alpha-1 receptors on the bladder. The beta-2 receptors are located on the bladder wall, so when they are activated it leads to smooth muscle relaxation which will lead to decreased urination (as the bladder is not contracting). The alpha-1 receptors are located on the urethral sphincter, so when they are activated it leads to smooth muscle contraction which will cause contraction of the sphincter which will prevent urine from exiting the bladder. So we can see how alpha-1 urethral sphincter constriction combined with the beta-2 bladder wall relaxation will synergistically cause urinary retention and decreased urination. Hope that helps! 🙏🏻
❤️
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