Fischer to Haworth and Chair for Glucose and Fructose (Vid 5 of 5)
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- Опубликовано: 2 окт 2024
- leah4sci.com/f... Presents: Converting a Fischer Projection to Haworth and Chair conformation for Glucose, and Fructose Fischer to Haworth
📺Watch Next: How to Draw Fischer Projections • How to Draw Fischer Pr...
Catch this entire video series + practice quiz and cheat sheet on my website: leah4sci.com/f...
Video 5 of 5 in my in my Fischer Projection series shows you my shortcut for converting from the linear D-Glucose to a Haworth Ring and chair conformation, and then a similar trick for converting D-Fructose from linear to cyclic form.
Chair Conformations Tutorial: leah4sci.com/d...
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I'm from Germany and even I was able to understand everthing. You helped me so much for my exam tomorrow. Thank you so much.
+Ellen Schrader ICH AUCH!
Ellen Schrader Abitur kann kommen :D
Warum sind Lehrer so inkompetent >.< xD
@@undeadscene8552 besser verstanden als in 4 Stunden Unterricht xD
Genauso :)
your videos are the best Leah. I survived OChem because of you and now I am taking Biochem and watching more videos from you. Thanks a lot!!!!!!
+Kim Hoang so happy to hear. Thank you and glad the videos are helping
This is a video that helped get An A- in my organic chemistry class in university. I really love all your organic chemistry videos. You saved my life in both organic chemistry 1 and 2. Your explanations are beyond clear and understandable and my tuitions money should go to you not to my professors. Thank you Leah for this channel. You are a gift from Allah :) Cheers
Thank you very much for your kind words!
God bless you you are a queen of chemistry!
What is the software you use for ghis online teaching
You are doing a great job,👍👍
Awww thank you!
i'll be having my exam with this topic next week and this is really a great help ! thanks a lot.
+Archie Cabachete awesome! glad to help
Not premed, but a very thankful nursing student! Thank you so much, this video was so helpful!
Thanks for the feedback! You are very welcome.
Thanks a lot Leah, i remember back when i was on organic chemistry that i watched a lot of your videos. Now that i got to remember some stuff for biochem i came across to your channel again and you helped me once more
Awesome! I'm glad to hear that my resources are continuing to help you!
Simply the best video on youtube! Such an amazing and clear explanation😊 can’t be grateful enough for your lifesaver videos🙂
Yay, glad it helped!
i've been struggling to understand how to do this and nothing seemed to click. After watching this video I understand this concept so much better. I am extremtly greatful.
That makes me so happy to hear!
Hawroth projection had been something to memorise for me . Thanks for revealing the actual visual concept. Thank you
You're very welcome!
my one and a half hour squeezed into this. Gee, thanks. All lot better.
You're welcome!
Your chemistry videos are the most helpful on RUclips! I understand chemistry because of your videos :) Love that your drawings are fast and that we don't have to wait for the drawing of lines/words or erasing like Khan Academy videos - can't stand them!
+Pearl Faraj thank you! glad you're finding them helpful
This video helped me so much for biochemistry! Thank you so much!
You're so very welcome!
Thank you so much. I kept getting my hw wrong when I just read the book then you helped me a lot! thanks!
You are welcome! Glad I could help!
thank you so much Leah....ur an angel
Aww thanks! And you're so welcome!
I'm a student of Medicine and i love to teach others, especially chemistry. What do you suggest? I think by teaching others at something you are good at you become even better yourself.
Absolutely! To be able to really teach any topic, you have to understand it at a high level. So if teaching is your passion, go for it! Thanks so much for watching and commenting!
OMG... this brings back memories. Thanks for the breakdown.
Pattie Cordova Thank you :)
This was so helpful! One question: If the carbons are numbered by priority for the D glucose molecule, how come for the D furanose carbon 2 is doubled bonded to an oxygen? Wouldn't that be highest priority?
The chain is numbered from the direction of the carbonyl, however the end of the chain still gets a number 1 making the carbonyl the lowest possible number on the chain (in this case #2 rather than #5)
Hi leah, first of all, you are AMAZING!
Second,just letting you know(if you didn't) , some youtube's accounts uploaded THIS video from your chanel to theirs
FYI
Thanks for your kind words and thanks for letting me know
Such a wonderful explanation!
Glad you enjoyed it
im so thankful, really really thank u 💜 u saved my life
You're very welcome!
Thank you Leah
You're welcome
i found this so useful thank you so much !! ^^
+Deanna Lum glad to help
Awesome video and great website quizzes! PLEASE add solutions to your quizzes so I can confirm I've got it!
I'm sorry about that, I will be uploading it shortly
Good job demonstrating this. It brought back memories from long ago.
P.S. I Love You Scrapbooking Thank you
Excellent explanation thank you
You're very welcome!
Thank you so so much. It's very easy to understand.
Glad to have helped! :)
A clear explanation of a complex subject. Well done. Thank you so much for taking the time!
+Branden Benson you're welcome. glad to help
You are beyond description,,, thank you so much
You are very welcome!
Thank you very much , nice work you explained it perfect!
You're welcome! :)
Is it safe to say that if it's a D-sugar, the CH2OH group points up and if it's a L-sugar, it points down?
Yes, that's what I gathered too.
agent475816 hmm D&L configuration is based on the postion of C-5 ( -OH )...
if OH if right it called D form and if OH is left it is called L form...but alpha and beta configuration is based on the postion of C1 with respect to postion of C6 in cyclic structure..if c1&c6 OH are in same side it is call beta form and c1 &c6 OH are in different side it is called alpha form
Yea, but I'm saying in the ring form, if the CH2OH group is pointing up, it's always a D-sugar and if it's down, it's a L-sugar. It doesn't matter whether it's alpha or beta.
Hmmm it's easier to determine the CH2OH whether it's up or down depending on the D and L configuration. 👍🏼👍🏼👍🏼 Thanks for mentioning that, I will depend on it. I see it's right.
That is correct!
Thank your for the clear tutorial !
please correct me if i'm wrong.
when you say [05:30] : when i draw Alpha, it (OH) goes down, and Beta, it goes Up.
this work only for D-glucose, for L-glucose it's the opposite.
the position of your OH on the first carbon depends on the position of the carbon 5.
if you want an alpha, then put your carbon's 1 OH at the same side of the carbon's 5 OH
if you want a Beta, then put your carbon's 1's OH at the opposite side of the carbon's 5 OH
+ismail ouriaghli (isbenj) The entire trick all the way up to that point is only for the D-glucose
wow!!!! thank you so much for the wonderful video. You see now im gonna flammox this chemistry test tonight
Awesome! how was your exam?
From Orgo to Biochem to the MCAT. I’m a lifeguard, but you’re the one saving lives!! 👏🏽🙌🏽
Lol. Thanks so much! Glad you found the video helpful.
Dear Leah can you please explain the chair conformation for glucose?
Explain in what way? Stability, how to draw or something else?
How to recognize if a compound is D or L by looking at the Haworth projection?
abhijeet baliga If the CH2OH is up then it's a D-sugar, if it's down it will be a L-sugar. But most sugars in nature are D-sugars.
thanks to both of you
Note that when when assigning alpha or beta it dependent on the CH2OH too,
meaning if the hydroxyl on the anomeric carbon points in the same direction as the CH2OH its a beta (since most sugars are D we kind off generalize and say up is beta but just watch out for that.)
Take a look at what happens to that specific carbon and OH group when converting from Fischer to a ring. Notice that on D the CH2OH points up, while on L it points down
Thank you so much 💓💓💓
You're welcome 😊
Thank youuu
You're welcome!
Wow! fascinating!
Glad you liked it!
Thank you very much, this vedio is gold❤️👍
Glad you liked it!
@@Leah4sciMCAT I loved it 🙂👍
The definition of an alpha anomer is that in the Fisher projection the OH at C1 is on the same side as the OH that defines the structure as D or L. The beta anomer is the opposite - in any sugar. This is when the ring is drawn to continue to the backbone up from C1. Also, the name Haworth is pronounced with a short a sound (not Hayworth).
Thanks for the feedback
Its really helpful
Glad you think so!
Thank you so much! I finally understand!
+Paula Noller awesome! glad to help
Tnx
Leah4sciMCAT very much !
You're very welcome!
Excellent
Thanks!
perfect!!!! i was looking for something like it for long time!
Glad to help
This was amazingly clear and saved me so much time. THANK YOU SO MUCH!!!
+Mark S you are very welcome! I love sharing tricks that will save you time on exams
wow that was so informative and seriously even I could follow along, this was not my thing in school!
Ashley Saunders Thank you. I found this really tricky in orgo/biochem till I figured out the trick. Glad you found it helpful
Thankyou sooo much
You're very welcome!
wow super helpful!!
Glad you think so!
thankyou so much
You're very welcome!
Thank you!
You're very welcome!
I have an exam on Thursday and I wasn't able to draw fisher to haworth. Thanks a lot !
+Marion Rebeaud awesome! glad to help! how was your exam?
Mam do you have a playlist for carbohydrates and stereochemistry
I have one for stereochemistry: leah4sci.com/chirality-stereochemistry-enantiomers-diastereomers-r-s-organic-chemistry-tutorial-series/
Hi Leah !
In the last example is it alpha or beta and how do you determine that?
Great question! In the last example, the groups coming off of carbon 2 are drawn with “squiggly” lines because the direction in which they point determines whether it is an alpha or beta position. If the OH group has a downwards projection, it is defined as alpha. If the OH group has an upwards projection, it is defined as beta.
is it true that all OH on the right of the fischer projection should be placed on the top when the molecule is in the haworth projection? That was what my teacher told me, but I'm having doubts. Please respond. Thank you
Using my trick everything on the right goes down as I teach in this video
Class 12 biomolecules ....anyone here????😊😊😊😊
Thanks for watching and commenting!
This was very helpful concerning carbon 5 of glucose orientation. I had a hard time explaining that exception to someone. Thank you for clarifying.
+crocketmeow glad to help
i really like the way you see it. it's fun.
+Zhia Rempola Thank you, hope it helps
Wow, thank you! This is fantastic! Take my subscription!
You're welcome and thanks for the sub!
thank you, thank you, thank you!! the ring diagrams were so confusing!
So happy to help!
You are such a life saver! You are not only preparing me for the MCAT but helping me tutor students along the way!!
Awesome! Glad I could help
Can we draw Beta-L-Fructose and Alfa-L-Fructose??
+Manasseh Akshay sure can
O.K. thanks ur video was very helpfull.
omg god!!! it really helped...thanks so much
thank you! glad to help
Leah may I know do U have other videos that describe the reaction of carbohydrate ?
All of my videos can be found on my channel page: leah4sci.com/mcatyoutube
Thanks for the great explanation and breakdown.
Joanne Greco thank you
So with six membered ring, we can convert a linear projection, into haworth projection and then into chair conformation. But if we get given a five membered ring like the one in the video, we can convert it into haworth projection but can we convert it into Chair Conformation????
+Alisha Negi chairs are 6-membered by definition
+Leah4sciMCAT thank you leah. I have just recently discovered ur channel 3 days ago and fair to say I have already watched 15 videos. U r a god amongst men. never thought I would smile while doing organic chemistry.
+Leah4sciMCAT so I was just wandering is there any weird way in which we could convert 5 membered into chair conformation or no.
+Alisha Negi you're more likely to get an envelope conformation
Thank you leah
Thank you! Thank you!! Thank You!!! I liked and subscribed. You just made my night easier. Home work due tonight and exam in 3 days, this was very well-explained. Thanks again
+Briste Belle oh wow glad to help
Please, I have an exam on Wednesday (tomorrow), can you clarify how to recognize enantiomers, Diastereomers and Anomers in monosaccharides? Please reply, Thanks
+Briste Belle If you're asking for a video series I'm sorry but I won't have those up by Wed
Leah4sciMCAT Never mind. It was this past wednesday and no not a video. I was thinking you could send a brief reply here..but thanks anyway. The video was helpful
For the L sugars, the alpha/beta rule is backwards, right? If the OH is down, it's beta, and if it's up, it's alpha? Because that's the situation I'm running into with all the L sugars I'm working with here...
D and L sugars simply refer to the placement of a single OH group, specifically the lowest chiral carbon. The approach for this trick still works, just make sure to swap that one carbon
awsome, but sill what if fructose is forming a pyranose ring
I've never thought of using the shortcut for it, but if you have the concept you should be able to apply it to anything
From a college freshman currently in biochem: Thank you!
+MostlyGamingVideos You're very welcome. Although I'm curious, how is a college freshman in biochem? Most of my students take biochem in their junior or senior year
t
Leah4sciMCAT I am taking intro to biochem courses and labs, they're required for all biochem majors at my school
@@Leah4sciMCAT We ,in India,are studying this in grade 12 in chem (in the chapter biomolecules) though we have taken phy ,maths , chem as our main subjects and are preparing for an engineering entrance test.... Really messed up
7:09 if ch2oh is the opposite of oh (the fifth carbone )we can distinguish between the D and the L in the cyclic form ?
if the ch2oh is up so it is the serie D ?
Yes, D will have the CH2OH up and L will show it down
In all honesty I did not understand a single thing and that might be due to because I'm very new to biochem. Please help me out.
+Cismaan Ali I'm sorry to hear that. How comfortable are you with the topics leading up to this video? Fischer projections AND sugars?
might be a stupid question but why is OH written as HO sometimes? I dont really understand that one
It can be written as HO to show that it is the oxygen that is bonded to the main carbon chain of the Fischer projection. It simply shows us a bit more about the connectivity of the molecule.
your tricks are life savers
You're very welcome!
how do you know that the OH on 5 is the one that attacks? Your videos are soo helpful. Thank you!
I'm so glad to hear that my videos are helping you!
We know that 6-membered rings are the MOST stable kind of ring structures and have minimal bond strain. By having the OH on carbon 5 attack, we form a stable, 6-membered ring.
Awesome.
Glad you liked it!
8:57 Me who is comfortable with chairs since the age of 8 :)
Too funny! But it took you until 8 to get comfortable with chairs? ;)
@@Leah4sciMCAT I guess before then i was comfortable with being carried around i guess haha
hahaha don't let my kiddo hear you say that. I'm trying to explain to him that he's hold enough to not need "mommy uppie" every 2 seconds
Amazing explanation! Thank you ❤
You're so welcome! Glad you liked it.
Useful almost 15 minutes 👍🏼 I understood it.
Glad you liked it!
hi i'm tin from the Philippines i'm a teacher thank you so much
You're welcome!
thank you so much your video was very helpful
You're very welcome
Thank you ma'am ...your video helped me alot
I'm glad you found the video helpful?
love it...
Thanks!
Thank you. u really helped me a lotttttttttttttttttttttttttttt
You're welcome, glad it helped!
Thank u very much your vidz helped me so much
You're very welcome!
Why OH on carbon 3 is on left hand side???
Thanks for the question! In both D-glucose and D-fructose, the OH on carbon 3 must be on the left hand side of the Fischer projection to portray the correct stereoisomeric form of the molecule.
Thank u thank u thank u so much for this video!! I had so much trouble understanding Fischer to Haworth and now I finally understand!! This is an amazing video! Will def recommend!
You're very very very welcome! Glad I could help
I was panicking because we have an activity later regarding this and I don't really understand my prof so I was looking for a tutorial here in YT and found this. THANK YOUUUU SO SO MUCH FOR THIS. REALLY HELPED ME💖😍
Glad I was able to help!
You make all the things too easy...and explains in very impressive manner....☺️ With cutest voice...marry me
Thank you for your kind words, but how about we keep our relationship professional?
great video....pitty that there is not chair configuration of fructose. On the other hand, what's more stable in terms of chair configuration, the alpha or the beta D-glucose? thank you very much.
You tell ME based on what I show you here :)
What do you think?
Clear explanation with brilliant tricks ;)) thank you for this amazing video
You're very welcome!
How can i draw fructose pyranose ?
Since Fructose has it's carbonyl at position 2, you form a 5-membered furanose rather than a 6-membered pyranose ring
what about D fructofuranose?
what about it?
this video really saved me thanks a lot
You're welcome! Glad it helped!
very clear explanation ...
Glad you like it!
thanks
You're very welcome!
So helpful. Thank you
You're so welcome!
The pain of seeing your friends saying for this great video as they understood and you absolutely didn't get anything 😔😒
I'm sorry that you weren't able to get it as your friends did. May I suggest watching it a second time to see if it clicks?
@@Leah4sciMCAT
That was a long time ago, I understood the concepts and my passed organic chemistry exam with an A
Life saver thank u😀
Happy to help!