Musculoskeletal System | Neuromuscular Junction | Neuromuscular Transmission: Part 1
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- Опубликовано: 29 июл 2024
- Official Ninja Nerd Website: ninjanerd.org
Ninja Nerds!
In this lecture Professor Zach Murphy will be teaching you about the neuromuscular junction, and the neuromuscular transmission. During part 1 of this series we will be discussing the action potentials carried by the alpha motor neuron, and the factors that play a role in the release of ACh, and the synaptoproteins involved with this process. We hope you enjoy this lecture and be sure to support us below!
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As a PhD student in muscle physiology studying and reviewing this stuff in preparation for my PhD defense oral exam, I can say that this information is expertly prepared and presented. Magnificent job here! Really looking forward to the second part.
Look in this myology playlist they are all there
Nnn.
I think I will release some Ach into the synaptic cleft to open my ligand gated ion channels to allow Na+ to enter my fiber cells and cause my Ryanodine receptor to open my sarcoplasmic reticulum allowing Ca+ to release and bind to my Troponin- C which changes the shape of Troponin- T causing my tropomyosin to move away from the active site of my actin allowing my myosin to bind to my actin which pulls my thin filaments using power stroke to finally get over one another
Which allows my palm and forearm muscles to contract in a way that moves my finger towards the like button and clicks it...
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Hehe
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you are the only reason i have not felt completely hopeless in properly understanding physiology yet. thank you so much
A struggling medical student here! Your videos are really a big help for students like me. Thank you very much and more power to you!
I’m with you sis! First year medical student and I am so grateful for ninja nerd lectures. I find myself recalling concepts he covered during class or exams. The way he explains is so much easier to grasp than my lectures
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Thank you. I've learned more in the first 7 minutes than in the 1 hour I spent reading my textbook.
Ninja Nerd You are really a Science Talented individual. You helped me to prepare my Neurophysiology exam and I hope this knowledge from you will contribute much towards my future career. Thank you so much for your time and hard work.
A. Godfrey It is EXACTLY taken from Dr. Najeeb Lectures...
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A struggling medical student here and I really love your videos. Sending love from Nigeria❤️❤️
As a med student, thank you for these videos. Very in-depth and not "dumbed" down, which I needed, especially regarding the specific proteins!
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Love from India😃🇮🇳
I can't thank you enough for these videos! They are such a great reinforcement to my professors lectures and my own readings. It helps me understand the material so much more and I am able to repeat it and teach it back to someone else. Absoutely love this channel as I am a pre-Nursing student going back for my ABSN at age 40!
Me too, but I'm 41! Nice job!! Love this guy...he's so great! 🙂
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I'm here after watching the first two videos on muscle physiology on your channel, but actually, I came here for anatomy of the muscle but I can say this first two video has really helped me more and I understand it more. thanks so much ninja nerd president.
Take a bow sir. Fabulous explanation.
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Starting Advanced Skeletal Muscle Physiology tomorrow morning - and this is a GREAT help! Thanks! :) You are a FANTASTIC teacher!
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This is an awesome help with understanding the physiology of the muscle. Thanks a lot!
AS always, you saved my day in my prep for the exam
i have my exams in a few weeks .. so glad i stumbled across you brilliant lectures thanks
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Good luck on the exam! - TG
Wow thanks, you’re lecture is just amazing! 👏
It really make sense how you explain it, Thanks
Hey ! I really love your videos, you're doing an amazing job and I hope you continue to make more stuff. One thing referring to the video: Isn't Syntaptotagmin binding the Calcium and in this way getting free of the Complexin-Protein which usually blocks the bindig of the other proteins? (Synaptobrevin , SNAP 25 and so on ) ? Correct me if I'm wrong :)
Even though I cannot fully extend my gratitude, thank you very much for this wonderful lecture.
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Meanwhile everything is happening at the same time. Acetylcholine synthesis is happing while calcium ions come inside the synaptic bulbs. And also acetylcholine is being released by calcium and snare proteins. So everything is happening simultaneously. You explained it really nicely. Appreciate your efforts and hard work for those who don’t get enough medical knowledge from actual school. Hats off 🥳
great vid, thanks.
which vid has the details of action-potentials, please ?
Dude, you rock. Your videos are freaking amazing.
i had two tests that showed the transmission was hypoactive on an emg so what do i have
Another great video! When the Na comes in, does the K come out as in the 3/1 ratio, still creating the + charge inside, or in this case is just Na? Also, what inhibits these ion protein channels as we know genetically, such as in CF when the Cl channels do not work, so these are acquired channelopathies. So my 2nd question is, can heavy metals such as Al, Hg, Pb, Cd, and chemicals block or inhibit these ion channels...
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Great overview, but what about Calcium-calmodulin and activation of CAMK II which phosphorylates synapsin?
this was so good I want to cry omg thank you
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Thank You, shared your channel with my classmates, you rock! You're a great asset for med school students. :)
Very detailed and well taught. Preparing for Frcophth part 1
I'm MPhil student and this subject is my minor subject. I always find this difficult but by these lectures I feel topics easy
Hoping I'll pass my class : D
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Hi, I have a doubt. Doesn't the protons move outside the vesicles down it's concentration gradient in the Vesicular Acetylcholine Transporter to allow the Acetylcholine to move in to the vesicles?
Great lecture as usual. Thanks a lot man.
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Thank you for this. Big hug for you. Keep it up.
Near the end of the video, as you were discussing potassium efflux for repolarization, would this relate to how a depolarizing NMBA like succinylcholine work?
You have helped me sooo much! I love how you explain then re explain for people like me that need that. You definitely need to keep teaching.
everything makes sense now. such a good teacher.
aynen çok doğru söyledin
how does the movement of protons aid the ach in entering the cell, like how is the exit of protons aiding the entry of ach
fabntastic, as always! thank you
Thanks
Great video, I know understand what the issue was, when I recently had to suddenly call an ambulance for my flatmate, and then in the hospital it turned out he had a lack of potassium, which made his muscles not be able to tense up properly
Thank you so much for your videos.
This is golden! Thank you
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Tbh I thought this chapter was going to destroy the A I have in A&P but this makes so much sense and is more detail than our textbook
Amazing!
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Thanks!
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Lot of luv ❤️from India 🇮🇳
Beautiful, well explained, Keep it up Dear
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