I am new to listening to Ari and Alex and I so love all the information that isn't fluff and lies but instead scientifically based. I purchased the energy blueprint and the fat loss and exercise blueprint. I look forward to getting absorbed in my new "education". So tired of decades of jumping from one diet to another, getting sucked into fads. Thank you for your hard work and dedication to truth and health.
Really, really good you guys. I knew these last 2 podcasts were going to be good when I saw Alex's name - and true to form he didn't disappoint. I particularly like the fact that Alex is so good at clearly explaining the concepts, gives plenty of analogies and is always so structured in putting forward his thoughts - plus the fact that he speaks so clearly and his audio quality is so good means that every point comes across crystal clear. I'm a corporate health coach here in the UK, specialising in metabolic health, and was so impressed with the comprehensiveness of these 2 podcasts that I've now added this onto the list of things I ask my clients to do in the early stages of working with me - ie to listen to these 2 podcasts rather than me taking 10 times as long to say the same thing! One suggestion to you both though - I'd love to hear Alex's considered response to the 'Bioenergetic' view of metabolic health as put forward by Jay Feldman (influenced by Ray Peat, but subtley different). Jay has a view on the causes of metabolic issues that are on one level quite similar to Alex's, except his explanation of why the cells cannot take up glucose from the blood is because the cellular machinery inside the cell is compromised to the point that it is unable to use more glucose for energy (rather than being stuffed full of energy as per Alex's view). Jay would say that this is a result of consuming too many PUFAs (both Omega 3 and 6) as well as environmental toxins/ plant toxins - but not from consuming too much glucose or fructose. Although I like some areas of this view (mainly the ones which overlap with your view) I see some real points of contention too. Still, it is incredibly interesting food for thought and I'd love to hear Alex's critique of what aspects of the 'bioenergetic' view of metabolic health he agrees with and which aspects he disagrees with - and why. Thanks again guys!
I don't think Alex is a fan of the Ray Peat, "too many PUFAs" school of thought. But thanks anyway for the kind comments and appreciative words. It's mean a lot!
37:50-38:55 Yes: going on keto is like going to the emergency room. It will get things under control quickly and allow you to make the changes you need on your path back to normality. I have a family member who had fasting blood sugar of 290 from untreated diabetes, he went on keto, and dropped it to 86 in 45 days. During that time, he started walking 1 hour a day and doing one set of pushups and one set of bodyweight squats to failure each day. Now, he eats more carbs (mostly fruits and vegetables) while continuing to doing the above workout. The improvements in body composition in just 18 months went from morbidly obese to 200 lbs. and 11% body fat. Parenthetically, literally no drugs or hormones were involved.
Thank you 🙂. Would like next podcasts with Alex. Complex view on hashimoto/sluggish thyroid & IR & mitochondria & methylation/ MTHFR etc. That would be great 💙💫
I am in the same situation: overtrained, undereating carbs, lack of sleep, hypothyroid at 50 years old. I finally healed my leaky gut/parasites and rebuilding slowly my metabolism & energy that crashed 6 months ago. My body had stopped converting food into energy and suddenly got belly fat and inner tighs from being around 108 to gaining (around 15lbs?).
@@TundeKovacs421 I don’t have IR now. Metabolicaly I am in a better place - Thanks to low carb, red meet, butter and IF/OMAD/2MAD. But once broken… you never know. There are subtle links between many things. My energy levels are low…
@@Mo-yj3wf Good for you! but the energy level is also able to predict a lot.. I have tried OMAD/ Keto with IF. Few month went well, everything improved but after I kept doing longer and my thyroid and gallbladder started to be sluggish and my mestruation also stopped. Since I am back eating 3 times, (mostly meat,fish, plantbased)but more carbs,working out, I feel better. yes, my A1C is higher now.. so I am trying to find the golden middle between:D:D Hope it won't take it again years.
Love when you have Alex on!!! I would love to hear more about strategies to avoid ultra processed food, that work in our modern world that is loaded with toxic food. How strict must one be? Can a whole foods diet promote fat lost if it contains conventional meat and dairy? I think so many of us know what to eat, but struggle because it is not easy to always make the best choices when we have life's stresses to deal with. Thanks for this great, informative episode.
I work in medicine (primary care). I've worked in family medicine, orthopaedic medicine, cardiology, and internal medicine over the past 36 years. Trust me...your insurance provider is calling the shots. We can make a plan to get you well and then their computers send us nasty-grams telling us to redirect. EMR may be the worst thing that ever happened in healthcare.
What if you have high A1c, pre-diabetes, NO BODY FAT, fitness instructor 15+ yrs ??? Eating organic, quality protein, veg, berries, quality carbs, fermented foods, fats. I blame stress !!!! Any answers for a 5’6”, 115lb female ?
To both of you...Are you just going by tests results? (Did you hear them discussing this)? Or do you have identifiable health problems rooted in everyday, tangible experience?
find emotional cause for this you can look in recallhealing (wich links you with your ancestors, NMH, Jaque Martel (qeebeq) has a good book al the best
My situation is the opposite, I have high insulin 33, normal A1C 4.5, normal weight yet I get blood sugar spikes with everything I eat. I don't eat processed, haven't all my life and have eaten low carb home cooked food organic, vegetables, clean water, excercise. I never had medical problems or took medications my whole life, until I tried birth control after insulin issues started with insomnia and low thyroid that goes normal low, normal again without medication.
Definitely MORE of Alex. One question I have. Perhaps I missed something about the issue of when the insulin receptors of muscles do not function properly. Just what causes this? Is this related to the xs fat that comes from the dysfunctional fat cells or are there other causes? Thanks for the extremely informative talk...and this, imho was NOT too technical so keep it coming. A Q &A with Alex would be great
In insulin resistance, cells gradually become less responsive to insulin's signaling, which leads to higher levels of insulin being needed to maintain normal blood sugar levels. This resistance can occur due to various mechanisms like: Downregulation of insulin receptors: Impaired insulin receptor signaling Increased serine phosphorylation Elevated levels of free fatty acids Inflammation Mitochondrial dysfunction Endoplasmic reticulum (ER) stress Thanks for the encouragement!
wondering thoughts on 5.5a1c, fasting insulin of 7 and consistent high fasting glucose...106 ish range. even when doing hardly any carbs. looking for 3 years for solutions and just told liwer carb and possibly berberine. dna shows biggest issue as high fasting glucose....
Look forward to a podcast for THIN HEALTHY FOLKS !!!! So tired of the GD fat loss and junk food eater podcasts- let’s be real - it’s stress- and mine is financial and won’t be changing in an ever expensive world. So I’ll go eat crispy cream I think!
You want a podcast about fat loss, diabetes and insulin resistance for thin, healthy people? (I don't think crispy creams are the answer to your stress problems.)
what an amazing interview, and Ari, you asked the questions I was asking. will def be watching this again.
Glad you found it informative. Alex is a great researcher.
I am new to listening to Ari and Alex and I so love all the information that isn't fluff and lies but instead scientifically based. I purchased the energy blueprint and the fat loss and exercise blueprint. I look forward to getting absorbed in my new "education". So tired of decades of jumping from one diet to another, getting sucked into fads. Thank you for your hard work and dedication to truth and health.
Thanks, Cheryl. I'm sure you will do just great with that education as a background!
Really, really good you guys. I knew these last 2 podcasts were going to be good when I saw Alex's name - and true to form he didn't disappoint. I particularly like the fact that Alex is so good at clearly explaining the concepts, gives plenty of analogies and is always so structured in putting forward his thoughts - plus the fact that he speaks so clearly and his audio quality is so good means that every point comes across crystal clear. I'm a corporate health coach here in the UK, specialising in metabolic health, and was so impressed with the comprehensiveness of these 2 podcasts that I've now added this onto the list of things I ask my clients to do in the early stages of working with me - ie to listen to these 2 podcasts rather than me taking 10 times as long to say the same thing!
One suggestion to you both though - I'd love to hear Alex's considered response to the 'Bioenergetic' view of metabolic health as put forward by Jay Feldman (influenced by Ray Peat, but subtley different). Jay has a view on the causes of metabolic issues that are on one level quite similar to Alex's, except his explanation of why the cells cannot take up glucose from the blood is because the cellular machinery inside the cell is compromised to the point that it is unable to use more glucose for energy (rather than being stuffed full of energy as per Alex's view). Jay would say that this is a result of consuming too many PUFAs (both Omega 3 and 6) as well as environmental toxins/ plant toxins - but not from consuming too much glucose or fructose. Although I like some areas of this view (mainly the ones which overlap with your view) I see some real points of contention too. Still, it is incredibly interesting food for thought and I'd love to hear Alex's critique of what aspects of the 'bioenergetic' view of metabolic health he agrees with and which aspects he disagrees with - and why.
Thanks again guys!
I don't think Alex is a fan of the Ray Peat, "too many PUFAs" school of thought.
But thanks anyway for the kind comments and appreciative words. It's mean a lot!
Thanks again to you both! I really appreciate the intelligence of your information. It makes so much sense and is very inspiring!! 🙏☮️💟
Thanks for watching!
37:50-38:55 Yes: going on keto is like going to the emergency room. It will get things under control quickly and allow you to make the changes you need on your path back to normality. I have a family member who had fasting blood sugar of 290 from untreated diabetes, he went on keto, and dropped it to 86 in 45 days. During that time, he started walking 1 hour a day and doing one set of pushups and one set of bodyweight squats to failure each day. Now, he eats more carbs (mostly fruits and vegetables) while continuing to doing the above workout. The improvements in body composition in just 18 months went from morbidly obese to 200 lbs. and 11% body fat. Parenthetically, literally no drugs or hormones were involved.
A useful example - thanks!
And yes - more of you and Alex!! 💗
Thanks, Paulette!
Brilliant video. Thank you 😊
Glad you enjoyed it!
Thank you 🙂. Would like next podcasts with Alex. Complex view on hashimoto/sluggish thyroid & IR & mitochondria & methylation/ MTHFR etc. That would be great 💙💫
Noted!
I am in the same situation: overtrained, undereating carbs, lack of sleep, hypothyroid at 50 years old. I finally healed my leaky gut/parasites and rebuilding slowly my metabolism & energy that crashed 6 months ago. My body had stopped converting food into energy and suddenly got belly fat and inner tighs from being around 108 to gaining (around 15lbs?).
I am in the same situation like both of you plus sluggish gallbladder. I have tryed keto but I cannot do that.
@@TundeKovacs421 I don’t have IR now. Metabolicaly I am in a better place - Thanks to low carb, red meet, butter and IF/OMAD/2MAD. But once broken… you never know. There are subtle links between many things. My energy levels are low…
@@Mo-yj3wf Good for you! but the energy level is also able to predict a lot..
I have tried OMAD/ Keto with IF. Few month went well, everything improved but after I kept doing longer and my thyroid and gallbladder started to be sluggish and my mestruation also stopped. Since I am back eating 3 times, (mostly meat,fish, plantbased)but more carbs,working out, I feel better. yes, my A1C is higher now.. so I am trying to find the golden middle between:D:D Hope it won't take it again years.
Love when you have Alex on!!! I would love to hear more about strategies to avoid ultra processed food, that work in our modern world that is loaded with toxic food. How strict must one be? Can a whole foods diet promote fat lost if it contains conventional meat and dairy? I think so many of us know what to eat, but struggle because it is not easy to always make the best choices when we have life's stresses to deal with. Thanks for this great, informative episode.
I remember Alex saying that his rule was real food but making sensible exceptions for healthy processed foods like protein powders.
Great podcast, thanks guys!
Glad you enjoyed it!
Thank you both. I loved your talking. I got a lot of information and I am very happy.
Glad you enjoyed it!
I work in medicine (primary care). I've worked in family medicine, orthopaedic medicine, cardiology, and internal medicine over the past 36 years. Trust me...your insurance provider is calling the shots. We can make a plan to get you well and then their computers send us nasty-grams telling us to redirect. EMR may be the worst thing that ever happened in healthcare.
What is EMR ?
@@butch843 Electronic Medical Records.
I've heard this before but sad to hear this confirmed by someone with their feet in the trenches.
@@butch843 Electronic medical records.
Ok. Thanks.@@annabethkarson9989
Excellent! GReat stuff as always Alex.
Glad you enjoyed it!
What if you have high A1c, pre-diabetes, NO BODY FAT, fitness instructor 15+ yrs ??? Eating organic, quality protein, veg, berries, quality carbs, fermented foods, fats. I blame stress !!!! Any answers for a 5’6”, 115lb female ?
That also describes me perfectly. Fat loss is not what I need....How do I get my A1qC down when I think I am doing everything right?
To both of you...Are you just going by tests results? (Did you hear them discussing this)?
Or do you have identifiable health problems rooted in everyday, tangible experience?
find emotional cause for this
you can look in recallhealing (wich links you with your ancestors, NMH, Jaque Martel (qeebeq) has a good book
al the best
I'd need more background to comment, honestly.
My situation is the opposite, I have high insulin 33, normal A1C 4.5, normal weight yet I get blood sugar spikes with everything I eat. I don't eat processed, haven't all my life and have eaten low carb home cooked food organic, vegetables, clean water, excercise. I never had medical problems or took medications my whole life, until I tried birth control after insulin issues started with insomnia and low thyroid that goes normal low, normal again without medication.
Definitely MORE of Alex. One question I have. Perhaps I missed something about the issue of when the insulin receptors of muscles do not function properly. Just what causes this? Is this related to the xs fat that comes from the dysfunctional fat cells or are there other causes? Thanks for the extremely informative talk...and this, imho was NOT too technical so keep it coming. A Q &A with Alex would be great
In insulin resistance, cells gradually become less responsive to insulin's signaling, which leads to higher levels of insulin being needed to maintain normal blood sugar levels. This resistance can occur due to various mechanisms like:
Downregulation of insulin receptors:
Impaired insulin receptor signaling
Increased serine phosphorylation
Elevated levels of free fatty acids
Inflammation
Mitochondrial dysfunction
Endoplasmic reticulum (ER) stress
Thanks for the encouragement!
@@TheEnergyBlueprint What would you say to the "keto People" and those like Ben Bickman who say that the main cause of insulin resistance is XS Carbs?
More from Alex!!
He's great, huh?
wondering thoughts on 5.5a1c, fasting insulin of 7 and consistent high fasting glucose...106 ish range. even when doing hardly any carbs. looking for 3 years for solutions and just told liwer carb and possibly berberine. dna shows biggest issue as high fasting glucose....
Are you heavily active and a health bodyweight? Perhaps start there?
@@TheEnergyBlueprint yes to both. triglycerides in the 40s and 5'6.5" 150lbs 50 yo female. slim waist with fat in butt and thighs
regular weight training , 3 hours zone w/ wk, and 1 hiit
Look forward to a podcast for THIN HEALTHY FOLKS !!!! So tired of the GD fat loss and junk food eater podcasts- let’s be real - it’s stress- and mine is financial and won’t be changing in an ever expensive world. So I’ll go eat crispy cream I think!
You want a podcast about fat loss, diabetes and insulin resistance for thin, healthy people? (I don't think crispy creams are the answer to your stress problems.)
Lipedema?
Not sure what you're asking.