ERGOTHIONEINE: Can This Little-Known Amino Acid Impact Longevity? [2024]
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- Опубликовано: 25 июн 2024
- Discover the secrets of ergothioneine, the latest "longevity vitamin" hailed for its antioxidant properties and potential to boost longevity.
Learn what it is and how it works in the human body. Explore its benefits and how its impact on longevity.
Don't miss out on this new vitamin discovery and its role in promoting a longer, healthier life.
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Chapters & Timestamps:
Intro: 00:00
What Is "Ergothioneine?": 00:31
How Does Ergothioneine Work: 01:06
How Does Ergothioneine Impact Aging: 03:42
Sources of Ergothioneine: 06:39
Dosages: 09:25
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Studies Referenced In This Video:
Ergothioneine promotes longevity and healthy aging in male
mice:
pubmed.ncbi.nlm.nih.gov/38446...
Ergothioneine and its congeners: anti-ageing
mechanisms and pharmacophore biosynthesis:
pubmed.ncbi.nlm.nih.gov/37561...
The unusual amino acid L-ergothioneine is a physiologic
cytoprotectant:
pubmed.ncbi.nlm.nih.gov/19911...
Ergothioneine, recent developments:
www.ncbi.nlm.nih.gov/pmc/arti...
Distribution and accumulation
of dietary ergothioneine and its
metabolites in mouse tissues:
pubmed.ncbi.nlm.nih.gov/29371...
Ergothioneine is associated with reduced mortality
and decreased risk of cardiovascular disease:
pubmed.ncbi.nlm.nih.gov/31672...
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Social Media:
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You're looking great, Lance. What you're doing is working. I'm not far behind in age but far behind in fitness, biohacking and training. You're the example to aspire toward.
Hi Lance - new sub here - I just wanted to say that I _massively_ appreciate your approach, your thoroughness, your impeccable attention to detail, and your refusal to 'dumb it down.' Thanks so much for what you do - you inspire me to vastly increase my knowledge. (I've even gone through over 100 3x5 index cards to aid me in learning the relevant jargon/terms.) Thanks for all you do, Lance! Cheers. 👍💪
Thanks, I appreciate that. Sometime this year, I'm planning on releasing a new course on the "Science of Longevity." This won't have any strategies or interventions to defeat aging, it'll be more about how the human body works at the cellular level.
@@LanceHitchings It's fascinating stuff to be sure. Cheers.
Publish your cards, please.
Good information Lance. Thank you. Getting on it right away!
Good channel. Good presentations.
Great video, thanks
Excellent to discuss a very important mushroom.thanks, Lance - much appreciated…
Thanks Lance!
You bet!
thank you very much Sir!!!for the absolutely valuable information!!!keep on the great work!!
Love this
Thanks
Another reason why Lion's mane mushrooms are essential and the make the most tastiest steaks
I take a home-made tincture of Lion's Mane mushrooms for it's cognitive effects.
Well done. Finally a video with new anti-aging information. I must have missed the 2009 memo as well!
I love all of your videos. Keep up the great work. We should study the lives of Greenland shark and the jellyfish. A Greenland shark is able to live up to 400 or 500 years. Jellyfish can rejuvenates itself.
Another excellent presentation. The perennial problem with mouse studies is that any intervention that protects them against oxitive stress invariably increases their lifespan by 30% (give or take). Humans oxitive stress protection is at least 6x better than a mouse, so any intervention that can support an already excellent system, is only going to add a small additional benefit. That said, as a frequent eater of mushrooms, I’m more than happy to add more porcini mushrooms to my diet.
I am a mushroom hunter, the season will begin here in Canada, in one month, exited to renew every year with my passion, and here another reason for it, can you verified the amount of ergothioneine in porcini, cantherella , trompet , and matsutake, thank you .
I like your comment because... I like mushrooms. Happy with my diet
Sirtuins activators can also act as a two edge sword. They can both suppress or promote specific tumours which can lead to certain cancers. There are many scientific and scholarly articles on this. It would be a lot safer and just as effective to use nicotinamide as it also upregulates NAD, but not sirtuins
LIke many aspects of aging, a double-edged sword.
@@LanceHitchings Thanks for replying Lance. As yet i've not seen any serious negative outcome for humans, only in rodent studies..perhaps sometime in the future we will have a better understanding
Doesn't David Sinclair claim that excess Nicotinamide will down regulate Sirtuin production?
Can supplementation improve symptoms once declines are noticed, or has testing only been done via supplememtation throughout the life of the mice prior to any onset of declines?
Is there a lab test to include in one's annual physical test battery?
Yeah I'm thinking we've made this all way too damn complicated. I'm feeling better than anytime in my life with focusing on protein and fats. I can now slowly start to incorporate things back in. I had antibiotics, this has wrecked my gut microbiome. Meat seems to finally be healing.
Good to know even the humble white button mushrooms can provide a reasonable amount 😊
Just eat mushrooms, they are delicious and healthy in many more ways along with ergothioneine.
7:21 King oyster mushrooms 3 oz = 400 mg?? ... or more like 4 mg ? of Ergothioneine
Google says 2.4-4.9 mg
Hello, have a question does kefir contain ergothioneine?
Not that I know of.
kefir contains L.reuteri, a gut bacteria which produces EgT.
Kefir cantains L.reuteri, a gut bacteria which produces EgT in the gut.
Kefir contains L.reuteri, a gut bacteria that produces EgT in the gut.
No, but it has L.reuteri, which produces EgT in the gut.
What kind of fermented foods? Kim chee?
Mostly tempeh and fermented rice. Here's a link to a chart listing ergothioneine amount in various foods: www.researchgate.net/figure/Ergothioneine-content-in-fermented-foods-and-mushrooms_tbl1_366899093
@@LanceHitchings It's good to see Beer is on that list!
Simple..
Can't assume that because a food has a lot of a nutrients, that it's bioavailable. I am now carnivore 8 months and feel 1000% better than eating "all" my vegetables. Just sayin'.😊
104 weeks 🥩
Another carnivore bot reacting?
@@VTVT1306Something a vegan bot would say.
@@FirstnameLastname-pe5ib 😝
@@FirstnameLastname-pe5ib just an omnivore who’s tired of the carnivore community and their hallelujah stories 😝
this is old news 2009.
Not all of us got the memo.