Coupling Reactions organic chemistry|Stille|Negishi|Sonogashira|Suzuki| Hiyama|Carruthers Chapter1
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- Опубликовано: 6 сен 2024
- #carruthers #organicchemistry #couplingreactions #stillecoupling #sonogashiracoupling #jchemistry
carruthers organic chemistry, carruthers series by j chemistry, william carruthers organic chemistry, modern methods of organic synthesis by j chemistry
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Heck Coupling
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Organometallic Compounds
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Maa'm, please start chapter two soon. Also Maa'm, can you pls teach heterocyclic compounds and coordination compounds? humble request.
Ma'am thank you so much, Plz continue this series and try to complete it before GATE 2021 it is really very very helpful.
Thanks Maam so much for this video. Aapne Heck coupling topic bahut hi acche se explain kiya hai, bahut acche tarah mind mai fix ho gaya.. aap bahut accha padhate hai. Jab bhi aap se padh kar mai questions solve karte hu toh aap samne aa jate ho( ki ha ye Maam ne aise explain kiya tha )aap ka face ,teaching way aapki voice 😊... aap bahut aache ho Maam. May God bless you. ❤❤❤
Thanks ma'am. Respect and regards
Si Ge and Sn has same electronigativity as 1.8
Thank you mam complete the chapter 1 ...........
At 26:15 otf is also present so why cl is choosen as leaving gp
I think Otf will leave ..beacause it has better leaving capacity than cl
Same doubt here
In 26:00, with the Benzene having both triflate group and chloro group why is the chloro group doing the Suzuki reaction? Isn't triflate a better Leaving group?
If you can understand it from HOMO-LUMO concept,
O is more electronegative than Cl. So sigma bond of C-O will have lower energy than C-Cl sigma bond, and therefore energy of sigma * of C-O will have higher energy than sigma * of C-Cl.
Now when Pd(0) will transfer electrons, it will change to Pd2+ and the electrons would like to go to sigma * having lower energy i.e. C-Cl
Aur jab electrons jaayenge anti-bonding mein, toh bond order zero ho jaayega, that means bond break karega C-Cl waala
I hope you got your answer :)
@@JChemistry Thank you for your response, Ma'am. It made things clearer. Meanwhile I also came across a paper by Prof Houk that has given good insight too. Attaching it here for reference. :) pubs.acs.org/doi/10.1021/ja9077528#
@@JChemistry Kindly do not take is harshly, but your explanation is not only wrong but misleading for many of your students who looks up to you. O is more electronegative than Cl, therefore all orbitals of C-O should have relatively lower energy than C-Cl, including HOMO and LUMO. So, the LUMO of C-OTf bond (sigma*) is LOWER in energy than the LUMO of C-Cl bond (sigma*), and NOT higher. This fact is also confirmed by the amazing paper by Houk et. al. whose link is given below. Thanks to @Surya Pravo Mookherjee.
I went through the whole paper and found out actual reason for this to be the 'coordination number' of the active Pd catalyst species. When PCy3 ligand is used, the active catalyst is bis-ligated (i.e., there are two PCy3 ligand attached to Pd), which makes the Pd species more nucleophilic (High HOMO) and therefore it attacks the bond with lower LUMO, which is C-OTf. for the other ligand PtBu3, the active catalyst is mono-ligated, making it less nucleophilic than the previous case.
Owesome!! Really owesome mam!!
Mam plz continue this series it is very helpful for us😀🙏
Mam when will u start chapter 2 😕
Excellent and decent explanation!!
Thank you!!
Thankyou for lactures of carruthers
Thank you mam 😊
Thank you
You one of the Good Teacher
Thank uh ❤️
Thanks 😊 well explained 👌👍
Mam plz complete book padana ,your expalanation is awesome
Suzuki reaction me bromine hi Kyu lete h Maam
Or baad me boron kaise ho jaata h..
Ma'am 26th ko to Nation wide strike hein so hum logoke exam hoga ya nehi hoga apke pass koi information hai kya???? plz ma'am
Abhi koi official information nahi aayi hai postpone ya cancel hone ki...so for now, exam is there on 26th Nov
I wrote to csir twice about this.but got no rply😑😑😑 don't know wheather i can reach the centre or not
@@sohinisarkar8715 kaha se ho aap
@@renumishra8924 West Bengal
Alhumdulillah
if we have 2 leaving groups.. like oTf and Cl... then kaise decide krenge.. which will remove
Thanks
Namaste mam nd thanks
Ma'am during the example of Suzuki coupling at 26 .20, why cl is considered as leaving grp instead of otf
same question here, otf is a better leaving group I think
same question here, otf is a better leaving group I think
Otf is good leaving group than chlorine
I>OTF>Br>Cl>F
God level lecture 🤗
Mam 25:50 main jo question hay usmain leaving group -Cl bhi hay aur -OTf bhi. To kaunsa group niklega wo kayse decide hoga?
Same doubt!!!!
Mam multicomponent reaction n domino reaction pe video banao
Hii di agar interviewe humko pucche ki...aap products synthesis me interested ho ya spectroscopy me to konsa jjyada achha rahega....
Thank you very much mam☺👌
decent explanation!! 👌🙏
Jordaaar mam
Excellent
Thank you mam❤️
Thank you mam
Very good explation. What is your name
TQ u dii
mam, why sometimes Pd is 0 state and sometimes it is +2
can we use k2co3 here.
Mam i very very and only believe you kya online coaching with you is sufficient for csir net crack please mam i know apke pass time nhi h ans krne ka please mam i am very confused solve my problem
Aap results dekh lena ek baari hydrogen helium batch ke, Uske baad decide Karna
Superb lecture
Thank you mam..
But..
Organic se bahut sareh qts the exams me... Mereh paper acha nahi likha
Maine organic chemistry jyaada bhi toh karaayi hai channel pe
Han mam. Actually. Maine zyada nahi kiya. Sorry.. But thank you soo much.
If i hurt u sorry.
Bas apse share kar rahi thi..
Thank you.. Soo much mam for every thing..
❤❤❤❤❤❤
Mam galti apki nai. Meri hai.mane nahi padha. But thnak you soo much mam. Meri galti hai. 3 subject me bhi aadha hi padha maine.😔
Revision hi karr rahi ho.
Thank you for rankbooster mam. ❤❤❤
Thank u mam 🙏🏻😘
Yes
💛
Nice video
Ma'am test Ka result Kab ayega?
hats off
Thnk u maam❤️🙏
Mam aj ka test hua tha ??? Vo nhi de pay
😍😍
30:55 why sonogashira and not hiyama? Please let me know If someone can explain
YES PLEASE EXPLAIN IF SOMEONE KNOW......
Bcoz reagents mentioned are according to sonogashira..
Mam , exam ke liye .. kuj tips bta dijiye . Please.....
tomorrow is last day , please upload one video.
Video will be uploaded tomorrow
@@JChemistry thankuu mam🥰🥰
@@JChemistry thanku so much mam
@@JChemistry mam when?
13:05
This is very nice explanation , Simply great❤👌
🤩🤩
Ma'am I'm 3rd year bsc chemistry honours mujhe jam ki preparation karni hai ksise admission le aapke
Tq mam🙏
Mam ...2021 k June csir net kii cls kb se shuru hogi..
Mam aap digital board pr kyu nhi pdate?..uss tarah jyada acha lgta h..apke sath contact bna rhta h🤪😊
Will do that after NET exam
@@JChemistry ok mam☺️
Mam aapki awaj acchi h
Mam up pgt chemistry jo important topic padh deajae
🙏🙏🙏
Mem mene abhi j chemistry aap pr cors lene ka try keya pr kuch pta nhi chl rha isleye kya kru please help me
Next batch will start after 26th Nov
You can join then
@@JChemistry thanks you
JazakAllah mam
Thank you
Thank u mam
Thank you