DNA methylation
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- Опубликовано: 11 сен 2024
- This video explains the process of DNA methylation and its importance in eukaryotic transcription using DNA methylase and Histone methylase enzymes.
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shomusbiology.w... PPT source- Dr. Anindita Banerjee, Department of Microbiology, St. Xavier's college
This was a very helpful lecture, thank you.
For when I inevitably revisit this video, or for the sake of others, here are some time stamps:
0:00 Introduction
1:25 DNA Methylation
3:23 CpG Islands
5:42 Role of methylases/different types of DNA methylation
10:56 Methylation and transcription
14:54 Cross talk between methylation and acetylation
17:08 Gene insulators as gene silencers
20:36 Role of an insulator - genomic imprinting
26:19 Protein (histone) methylation
29:52 Coupling histone methylation and DNA methylation
34:10 Heterochromatin and euchromatin silencing
You didnt state the time stamps?
You are really born to solve life science problems. Thanku
Thank you. Glad you liked my lectures
I would like to thank you for the video, which saved my darn important time. saw your video and then did a quick reading... the concept is clear. Thanks, thanks thanks
Glad to hear that you're getting benefit from my lectures. Please subscribe and share
Dna methylation - Turns off transcription
Histone acetylation - Turns on transcription
But as the Histone methylates, whether the transcription turned on or off ?? What happens when histone prtn methylates??
I am a self learner ,familiar with DNA RNA ,RECENTLY CAME ACROSS WITH. METHYLATION which looks very interesting
Reviewed a lot of lectures ,understood them partially , now I am left with some questions about why methylation happens ,is that the only factor for cancers
What is the difference between. The sequential mutation and methylation ending to mutation any reply is greatly appreciated .an old time student
U are best teacher
Thank you so much for appreciating my efforts
No one can teach like you..
Thank you so much for appreciating my efforts
I like all of your videos. Very informative and clear. Please could you do a video on CpG oligodeoxynucleotides.
Thank you so much for all your videos. Could you make a video on cell signalling, MAPK ie ERK Pathway, please?
excellent talk..complex topic simplified in lucid manner..thanks a lot
Good morning , a question please, in practice does hypermethylation or hypomethylation predispose to tumors? Thanks
this lecture was very helpful...omg..i have a better understanding now...thanks a million!!!
Lecture was so helpful. Thank you sir.
You're welcome
hi
how can we download these slides for studying ? i can not find them in the website mentioned above
thank you
I find this video very useful. I now understand the topic better. Thank you
+Oluchi S. Glad it helped
!!!!! Thank you so much, Sir, this helped me a lot!!!!!
You're welcome
Methylation of CpG occurs in CpG poor regions and CpG rich regions (CpG Islands) of the DNA are seemed to be protected from methylation (Lim, Maher 2010).
Please clarify if CpG are really hotspots???im confused
just excellent.............very much liked
Read this pls..i just took a tetanus vaccine and it has differential extraction-methylation CAN THIS CHANGE MY DNA ?
Hi.. bro... Can you provide the references of your video..?
video is too good,,thank you sir for this video..
Glad you liked it
Would you please explain what is the MBD2 protein size, binding/active sites and how many DNA probes can binde with one MBD2 protein..??
Can you please make a video on dna methylation in bacterium (prevention of self dna from restriction enzymes)
Could you please make a video of how to identify the genes promoter region and methylation status in the promoter regions by different software?
Thanku sr ....its vry helpful but there is little confusion dat sm CpG get methylate and sm CpG which r located near promoter & enhancer region not methylated,...? Hw is possible?
Sir plz make a video on ..... Core and minicore topic
Thank u sir.very well explained
THANK YOU SO MUCH BRO
Question..... can anyone explain or give clarity on the following ... does any change to typical Purine & Pyrimidine, folate, B6 or B12 pathways during pre or early post natal periods result in heritable genetics that could be passed from that baby should they procreate in later life?
Plz sir make a video on ..... Core and minicore
Very useful video.thank you
Beautifully explain, thank you! :)
very helpful. thank you for uploading.
very helpful sir
You're welcome. Glad to hear that you're getting benefit from my lectures
I can't find the ppt for this lecture
how would this work in the Steven Avery case?
Why METHYLATION TAKEN IN 5 carbon position of cytosine, and why not it taken on other nucleotides bases
how to download this ppt? please
thank u sir............................
Wow nice video. .
You're welcome
Who can help me way to download the ppt in this video
Explain how DNA methylation is passed on to daughter cells.
excellent..:) thank you
Good explanation!
i can not find this material in the web page, can you help me?
thanku sir :)
Fariha Jutt gufm
really great...its vrey usefull
You make easy to understandable topic more complicated.....u must work on yourself
Thank you
it is all OK, except that DNA metaylation :-) should be DNA methylation
Read this pls..i just took a tetanus vaccine and it has differential extraction-methylation CAN THIS CHANGE MY DNA ?
@@bonk8594 your DNA is changing every day. Everyday, every cell in your body receives about 10 thousand DNA damages, changes, because you breath oxygen, and aggressive chemical. That is what we call aging :-). Most of the damages get repaired, but if you live long enough the damages will not get repaired, and you will get cancer, or some other disease. Nobel price in chemistry in 2015 was give to the people who described all of that :-)
@@zeljkom.svedruzic8406 i can see you know alot about DNA thank you i was scared a lil bit i didnt want the vaccine to change my DNA..so i started reading about DNA methylation and got scared but now i know that DNA changes all the time. What do you think is the best way to prevent cancer you said that DNA gets dameged ? And do you know how to improve your DNA so it dosent damage to much ? Thank you Željko and have a great day !
Is the euchromatin silencing by HP1 natural or a tumorous phenomenon?
This is difficult and complex 😣
I love you Suman, that is all.
God damn this is one long video haha
so long explntn..can u plz a share a short video about it
Sir please Indian English bolne se acha hy Hindi mein he lecture deliver karein.
Please sir Hindi me vedio banaya kijiye
Okay
@@shomusbiologyofficial thank you so much sir
This is difficult and complex 😣