the way you explain, makes all nonsense stuff and complicated study into simple and understandable education, is really amazing the way you teach us. thank you so much i had followed your clips since my GCSE
What you say at 5 minutes 50 seconds is not true. H2B-H2A dimer and H3-H4 dimer do not first combine to form a tetramer. Instead, two H3-H4 dimers combine to form a tetramer, and then two H2A-H2B dimers combine with the tetramer to form the octamer that will be wrapped in DNA to form a nucleosome.
TQ TQ TQ TQ sooo much for all ur vedioes we are blessed to c u in RUclips brother becouse from last 3 semister iam following ur vedioes only very detailed information I hard from u I dint written in nodes also directly i attempted I am getting 80% from last 3 sems TQ bro
For months I auto-skipped all of this guy's videos due to the accent. Then I watched one out of desperation, and it's extremely good wtf. I missed out.
Hello ! It's not two tetramere of histones that make an octamere. It's one tetramere of H3-H4 + two dimere of H2A-H2B. I am not sure you said that in your video. Sorry if I made grammar mistakes I am not an english speaker.
Thank you very much.... is there a video that explains the DNA in the mitochondria which do not have histones and how they become compacted as in the nucleus?
No sir, I think h3,h4 formed a tetramer, then it bound to the DNA, recruits two copies of h2a h2b dimer and completes the octamer in this way. but u said that the (h3 h34 h2a h2b formed a tetramer)*2.
Nice video and easy to understand, but i have a question. U mentioned it was an octomer protein with 8 subunits of histones, there are only 4 mentioned in the diagram, where are the other 4?
the way you explain, makes all nonsense stuff and complicated study into simple and understandable education, is really amazing the way you teach us.
thank you so much
i had followed your clips since my GCSE
Every time I'm going through my medical genetics lectures I have your page open on a tab. This is so helpful, thank you so much!!
I am a class nine student and was in a trouble to realize it but now I have gotten full concept. Thanks a lot.
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this is a great explanation! I just spent 2 hours trying to read a chapter of a textbook on this but you cleared it up in 13 minutes :)
Thank you so much for appreciating my efforts
everytime I'm lost and confused this guy saves me okay. THANK YOU VERY MUCH!!!!!!!!!!1 YOUR VIDEOS ARE SIMPLY SO HELPFUL THANK YOU VERY MUCH
Amazing capacity you have to handle the classes. I am 63 yrs, but still enjoying your class. Best wishes
I am glad to hear that you're getting benefit from my lectures
The way you explain the difficult topics is amazing.. I admire your way of teaching.. Simply awesome
What you say at 5 minutes 50 seconds is not true.
H2B-H2A dimer and H3-H4 dimer do not first combine to form a tetramer.
Instead, two H3-H4 dimers combine to form a tetramer, and then two H2A-H2B dimers combine with the tetramer to form the octamer that will be wrapped in DNA to form a nucleosome.
Hydra572HQ exactly you re right dude
Thanks a lot
@Porter Kyng nobody gives a damn bro
TQ TQ TQ TQ sooo much for all ur vedioes we are blessed to c u in RUclips brother becouse from last 3 semister iam following ur vedioes only very detailed information I hard from u I dint written in nodes also directly i attempted I am getting 80% from last 3 sems TQ bro
Thank you so much for appreciating my efforts
For months I auto-skipped all of this guy's videos due to the accent. Then I watched one out of desperation, and it's extremely good wtf. I missed out.
Thank you so much for appreciating my efforts
Amazing how you make these sometimes complex mechanism relatable and fun...good job!
+temple2infinity thank you. Glad you liked my lectures
THANK YOU ! YOU'RE THE DISCOVERY OF THE DAY IG ! 13 min felt like 2 min ❣️
Good job Shomu! You have incredible passion for teaching.
Thanks... Amazing, simple, brief, clear and well explained
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Omg..it is an amazing lecture...I was so confused for the concept of histones but now I am cleared very well....keep it up sir👍👍
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This was a great explanation! Thank you!😊
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sir ur teaching skills r amazing. thank u for such kind of videos. 1000 likes for u sir🙂
This man has a video on every topic I search for and I like it✨✨
Thank you so much for appreciating my efforts
Thank you a lot ! You make this topic much more accessible for students !
0.6 mm is too long for the condense form to package inside the nucleus .
But your way of information titling is wonderful .
Thank you so much for your share ! The interpretation is easy to understand.
Hello ! It's not two tetramere of histones that make an octamere. It's one tetramere of H3-H4 + two dimere of H2A-H2B. I am not sure you said that in your video.
Sorry if I made grammar mistakes I am not an english speaker.
Really?
Very informative
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Your videos are awesome to understand and easy....
Thank you. Glad you liked my lectures
really awesome kind of job u r doing ...otherwise students like us would have been in a huge problem. thanks for providing such a good lecture
Glad to hear that you are getting benefit from the videos
Thank you very much.... is there a video that explains the DNA in the mitochondria which do not have histones and how they become compacted as in the nucleus?
becose mit dna circle form
WOW...Awesome Teaching Man...
Thank you sir
Your classes are very helpful🙌
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incredible teacher
Shomu bhaiya tnk u ...
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Its a really soo helpful ...Bundles of thanks for providing us such an excellent site
Thank's dr💙💙💙
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thank you for sharing the knowledge
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Simple and direct into the point... amazing❤❤
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Very nice n simple way to explain. Keep up the gud work
Thank you. Glad you liked my lectures
Please make some video on non histone proteins as well (like the HMG proteins). Thank you, this video was awesome!!
Thank you so much for this lecture!🤗♥️
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You have great energy. You make learning fun!
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Thank you so much bhai😭
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amazing.....
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Well Explained
Thank you
tnx sir literally ur way of teaching is amazing
so helpful. thank you
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thank you so much
+Reshma Samanta you're welcome
Thankyou sir❤
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Your teaching skill is amazing!!!.God bless you :)
Thank you. Glad you liked my lectures
your knowledge and specially method of teaching is really amazing ...
+Sana Rani thank you. Glad you liked my lectures
Thank you so much!
Sir, what is the ratio of protein and DNA amount in chromatin?
Pls teach us biology for NEET as well
But in detail like this 🙏🏼
Amazing teacher
Thank you so much for appreciating my efforts
Tq sir for your efforts
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Hi. Can ı ask your something? where is the Histon1?Video is sucsessful.
Sir it's absolutely amazing..! The way u Explain everything is just incredible
Thank you so much for appreciating my efforts
thanks for this explicit and concise video
thanx a lot..amazing exlanation
The cell size is 10 to 100μm in diameter and the .6mm makes 600μm, kindly clarify. Thanks. By the way your way of explaining is amazing.
Thanks, mate. fantastic explanation.
Sir what about the H1 histone protein?It does not form a part of the nucleosome but it forms a part of the histone family.
sir plz tell me where is methylation or acetylation occur at c or N terminal
thank you too
You're welcome
2 questions....
why some receptors are stable at cell membrane & why other are at cytoplasm ?
what is novel mechanism of stability of protein?
My Knowledge is kind of Naive but it has something with Hydrophobic and Hydrophilicity of Proteins associated with the Receptors.
Bhaiya what is this N tail... Could please explain me i am in class 10 that's why I am not getting it
great video sir.plz make some video on colligative properties
+Poonam Dixit surely do
sir, what is the function of Histone (H1) beside linking?? (if any)
wonderfully explained. thanku
I m preparing for csir net Dec 2018 by watching yr vdos.. hopefully I'll let u knw about my positive result...
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Nice explanation sir, thanks a lot... really I'm very grateful to you
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Thnq for the knowledge u share..
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Really helpful
very interesting, induce me to learn more thank you
Perfect sir ❤️💯💯
Thank you
Excellent!!!!!!!!
Thnku sir for this lesson ☺️
You're welcome
Thank you .it's really good n easy to understand.
+Chibeni Ezung thank you. Glad you liked my lectures
my final exam is tomorrow I hope that I get the highest score and you explained this very well:)
Thank you so much for appreciating my efforts
what are non histones and its functions?
Thanku so much sir
You're welcome. Glad to hear that you're getting benefit from my lectures
sir euchromatin lecture is very good thank you
You are so F so smart!
very nice shomu sir great explanation👍
What about H1 type of histone? Should be 5 types
what is that exit site sir..?
Gd teaching sir
Thank you. Glad you liked my lectures
May god bless you Sir 🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏
You're welcome
Best 👍
Thank you
Thanks Sir
You're welcome
good thank you
Please help: Are the nucleosomes at regular distance from each other? If not what is the reason?
Sir...why histones are highly conserved ??
Its a part of epigenetics ???
Plz tell me tomorrow is my presentation
sir ye feet wala data kaha se leya mujhe dout h ye wrong h
Thank u sir
You're welcome. Glad to hear that you're getting benefit from my lectures
No sir, I think h3,h4 formed a tetramer, then it bound to the DNA, recruits two copies of h2a h2b dimer and completes the octamer in this way. but u said that the (h3 h34 h2a h2b formed a tetramer)*2.
I said that all these 4 subunits formed octamer presenting 2 times each. I didn't cment on the sequence of their arrangement
@@shomusbiologyofficialBiology ok sir, got it.
Give examples linker proteins?
Nice video and easy to understand, but i have a question.
U mentioned it was an octomer protein with 8 subunits of histones, there are only 4 mentioned in the diagram, where are the other 4?
4 subunits 2 of each unit
What is the angle DNA form during entering the histone octamer?
Excellent information, l but
there is a need of explanation speed should be slow, it is to much fast.
Please do a video on dna packaging sir...
Man.. U just awesome!!
Thank you. Glad you liked my lectures
well done sir, keep it up
You're welcome