@haircafekevin I came across probably the most dramatic meta study about DHT : www.ncbi.nlm.nih.gov/pmc/articles/PMC7308241/ The author claim that DHT utility has been undervalued a lot, and therefore the danger of finasteride and dutasteride vastly underestimate. Do you have any angle on that ?
Reddit has recently gon crazy over a supposed result from hmi-115trial after 2month…. Whatever Whats youre short opinion on pelage? Starting phase 2 trials soon looks somewhat decent, funded by some Ucla scientist. Always loved the vids on new treatments, eventho we yet dont have a new growth stimulator.
I think I'll hold off on giving my official opinion on PP405, pending a full video on the subject. As far as HMI-115, I don't think we can conclude anything from one leaked result. We don't know if it is representative or an outlier yet.
in italy “Clemente” 1L olive oil, which is one of the highest quality commercial olive oil is 14€ or something like $18, and i think its quality is better than the Bryan’s one at 1/3 of the price
@@haircafekevinhi mate, i’m norwood 0 but following you just for your thumbnails, and have to admire you gave me big laughs and I am often sharing your video thumbnails with my friends like memes. But i want to ask you seriously, what is your problem with tim pool? İs it bcs he’s hiding his head? can u make one video about him and Ana? You investing so much time on making Memes of this 2 😂😂 thanks chum! :)
Anyone see the photos of Tim Pool at the summer pool party... still wearing his hat. I would be so happy for him if he got a hair transplant. There is a better way!
It's always hilarious when you use that thumbnail / clip 😂. Especially for us Irish Chooms. It's from an Irish TV Programme and that's Ray Foley (funny irish guy) as the presenter.😅
Watching these I keep thinking Kevin shouldnt keep his ability for deboonking restrained to the hair loss world only. We need you to pwn the dietary supplement scams, lifestyle scams, etc. You are the fist of truth.
Hi Kevin, does minoxidil gains permanent as long as i use it or after enough time i will lose all my gains and return to baseline? if so what is the point of using minoxidil (while using fin )for lifetime if it only works for 4-5 years? not to mention if you stop your hair become even worse. im nw 2 with long hair. hairlineis not that bad but my main problem is density.
Yes, minoxidil works indefinitely. It only loses its efficacy if you use it by itself since it doesn't block dht. If you use it with finasteride it works forever.
I’ve watched all your DUT videos multiple times. They provide great insights into Fin versus DUT, highlighting how DUT may have a similar side effect profile to Fin, if not better. I’m interested in hearing your thoughts on the 75-patient study that examined the reduction in sperm count. As a 22-year-old, this concerns me about potentially having kids in the future.
I'm not sure if you mean this study, academic.oup.com/jcem/article/92/5/1659/2598215 . It showed mild reductions in sperm counts that reversed on stopping therapy. In the majority of men these changes would not affect fertility, but in men with borderline sperm counts to begin with it could. Sperm counts do go back up when stopping treatment in all the studies I have seen, but most of the time it is nothing to worry about.
@@haircafekevin In a study comparing dutasteride vs placebo, 27 healthy men took dutasteride, 0.5 mg, daily for 52 weeks and completed 24 weeks of follow-up.47 At 52 weeks, compared with placebo, dutasteride treatment resulted in a reduction in sperm count, semen volume, and sperm motility (23%, 26%, and 18%, respectively). There were 2 participants in the dutasteride group who had decreases in sperm count that were greater than 90% from baseline at 52 weeks.47 At 24-week follow-up, all semen parameters were within normal range, except for sperm count, which remained decreased at 23% lower than baseline.
@@prav077 If you read the rest of that section of the article, there is a second study where the decrease was not statistically significant at long-term follow-up. Like the article says, the decreases in sperm counts probably are not clinically important in most men and don't affect fertility, but there may some men who have a greater decrease that could cause fertility problems. If this is a concern, the data on 1 mg per day of finasteride might be more reassuring to you, so maybe you should just use finasteride.
(theory) Im a big fan of him but I have doubts that Brian Johnson is doing much. I fear that it`s just his team of doctors simply doing whatever is proven to work (or what they think works) I`d say other researchers or even the average Redditor on r/supplements is more knowledgable than his team
What's the most effective and safest way to switch from Fin 1mg daily to Dut 2.5mg daily. I've been on Fin 1mg daily for almost 3 months and want to switch to Dut 2.5mg daily. I am thinking of taking Fin 1mg 5x a week and Dut 2.5mg 2x a week then gradually dropping Fin over the course of a few months (less Fin 1mg, more frequent Dut 2.5mg) and eventually taking only Dut 2.5mg daily. Would this work or not, or is there a better way to do it? Have you already covered this in a video? If so, send me the video please.
I'd maybe just try it once or twice per week with fin on the other days to see how you respond, and then switch to 2.5 mg daily if you're comfortable with it.
Hey Chooms, hey Kevin !! 👋 I started adding 2.5mg dutasteride on every sunday on top of the 0.5mg dutasteride I take as usual everyday. My goal is to regrow more hair (basically, despite better regrowth on dutasteride than on finasteride, I still have plenty of miniaturized hair that just won't get thicker....) and my goal is to also regrow those thousands of still miniaturized hair. I've also been on topical minoxidil for years so you guys know. I will update on HairCafe's channel in 6 months and in a year to let you guys know how it goes (whether is makes a difference or not).👍 Might even upgrade to 2.5mg dutasteride twice a week on top of dutasteride 0.5mg everyday later if I have to (hair greed I know) . Wanna do that until GT20029 is out on the market to maximize my regrowth
Dut is almost a cure. I’m thinking of hopping onto the master race myself, just scared about It’s effects on sperm counts, I’m 22 almost and that’s also a concern for me.
Kevin, please make your next thumbnail Jordan Peterson saying to Tim Pool "Sorry. Not beautiful. And no amount of authoritarian tolerance is going to change that."
Hey Kevin So I had a video call with a well known hair surgeon here in europe this week. After telling him my hairloss history, he suggested the following medical therapy: - Switching from dutasteride (after 9 years on it) to oral finasteride 1 mg, 1 tablet per day for 1 year. Reason: My body has most likely built up a tolerance after 9 years of dutasteride. The surgeon has also observed in other patients that the effect of finasteride/dutasteride diminishes after 5-7 years. Tolerance should be resolved with the interruption. He, calls this window therapy. Have you already heard of fin/dut tolerance and the effetcs after taking a break from it? I found two videos about this topic on RUclips: ruclips.net/video/J1cuW86cklw/видео.htmlsi=Y4Mts4eFGf0PP30k ruclips.net/user/shortsqpW-v2EqNzo?si=J4_PuRBntS4OCm46 What is your take on it and have you adressed it? Thanks for helping out!
Sup Kevin, I’ve been seeing lots of people online vouching for Batana oil for hair loss. Can you make a video giving your opinions on it and comparing to something like rosemary oil maybe. Thanks.
That's based on very weak observational data from Asia. I've addressed it in some of my Rob English videos. There's no solid evidence at all that this is true.
@@haircafekevin Thank you though I do think hairloss could technically be at an all time high since most countries are aging and older people have less hair
Mr. Kevin Mann can we get some lifting videos like the old times? I lost a little bit motivation for lifting due to an injury. And also kevin, how do you manage injuries while lifting so heavy. I'm 22 and whenever i lift even a 1/3rd of your number i just tear something. I feel like strength is very genetic and i haven't been able to bench 205 even after 3 years training. How do you manage injuries basically and can we get some training footage choom. Maybe a bench press or something.
Any idea why there has not been any progress in making synthetic hair? Like, how can we have implanted fake teeth but not implanted fake hair that does not cause infection and other negative side effects? To me it feels like it has to be a more tractable problem than e.g. hair cloning which is cloning an organ and therefore basically final boss of medicine.
Hey Kevin, really love your content since you were the one convincing me to fight the curse rather than just letting my hair go away. I was wondering if you would do an update on your hair transplantation video. In your video you are on the side of Fue, however there are several points where I would be interested in your opinion. -FUT has better growth yields than FUE -FUT preserves the donor area There are some papers discussing this. Also the videos of Dr. Bloxham recommend starting with FUT. What is your stance on this topic? Clearly you were quite succesful doing FUE.
Hi Kevin, hope you are feeling better. A quick question. Ive seen a commercially available exosome product here in the UK called E50. When I’ve looked deeper into it, the exosomes are captured/cultured from salmon testes apparently. I just wonder if there is any data on if all exosomes are created equal, not only in terms of parent progenitor cell type, but also species type. Can we expect salmon testis derived exosomes to be as effective in hair regrowth as human dermal papilla cells derived exosomes?! My guess is probably not, but that’s complete speculation. Any thoughts? In truth I am considering trying it out as financially I can take the hit for afew months of experimentation. Thanks in advance.
Well chooms, after a year and a half on finasteride I am still experiencing hairloss (much slower than it should have been, I'm sure) but still progression wasn't halted. In turn I need advice - anybody know where I can order dut online outside the US? And also, a good place for hair transplants (not in Turkey) with decent prices?
@@migostrigos5436 Spain is interesting will check it out. I'm not from the US but I need an online pharmacy I can buy dut from, in my country only fin is approved for hairloss.
Me the 20 yo with dupa, retrograde and regular pattern hl (probably started at 16 yo) has experienced some hairgrowth after 6 months finasteride along my 1.5 nw hairline, so much that it regrew to 1.25 nw, but my dupa continued to worsen after 3 months into fin again, as did my retrograde. Isnt this a sign, that fin is not enough for my dupa and retrograde?
Could just be a seasonal shed. I would give it a few more months to stabilize and if that fails maybe consider 2.5 MG of dutasteride for double finasteride's scalp DHT suppression.
Yo kevin, does hair system cause more hairloss? I think i will just go for a hair system untill some good cure shows up because i dont want to risk my donor area for a ht at the moment, and ofc ill keep taking fin
Hey Kevin, hope everything is nova. I was thinking about one thing, if i had a great shedding when I started fin, and i am having a considerable regrowth rn with fin/dut, how likely is it that i will continue to have gains over the next few years? Taking into account that just finasteride was enough to give me some gains, and now I'm on dut 2.5mg daily. Im 21 btw and my hairloss started at early 19.
Your chances of regrowth are very good. In the clinical research, even finasteride alone caused some regrowth in 60 percent of users (the remainder got maintenance), and you're on a stack that is significantly stronger than that. Peak hair regrowth will likely happen by year 2 but there is research on finasteride showing it continuing to give regrowth even after 10 years so I think you will very likely see continued benefits for many years and you will be able to stop any further hair loss indefinitely.
@@haircafekevin That's good to hear, if I can at least bring my hair to 80% of the density it had, i'll be very happy, and it would save me a lot of grafts for a future HT. I think i'll wait up to 2 years of treatment to decide whether or not i'll need HT.
Yes, it is on my agenda. Unfortunately, I have to do a response video to some moron first so it won't be the next video. I Will try to get it out soon after that though.
When I got my Hair Transplant done my clinic sent in some of my fair follicles to a lab to harvest and freeze the Sten cells for future use. I wonder if they can separate the exosomes as well
Great vid! also, how frequently would a person need to take 2.5 mg dutasteride along with their normal .5 dose? would it have to be EOD, weekly, or ED?
Hi Kevin, amazing video as always. I was hoping you could make a video about the new study that was published this year in February, about how finasteride down regulated some genes in the hypothalamus of mice and could it be concerning for humans?
I usually quote the absolute risk, which is risk on drug minus risk on placebo. So that's about 2%, though obviously in some studies it is more, and in some it is less. Overall I consider the risk to be low.
Hey Kevin! I recently got Finasteride perscribed and I'm thinking of microdosing it since my hairloss isn't aggressive and im still young and about a norwood 1.5 or so. I wonder, if I start off with 0.25mg a day lets say, if it works fine, should i keep taking it forever, until lets say a few years later if i start losing gains and experiment with upping it to 0.5mg a day and go on from there? And lets say if i dont lose any ground in a few years, can i take 0.25mg forever? This is just hypothetically speaking, i hope you understand. Thanks man!
interesting stuff, first time I’m hearing about any of it. thanks for the info as always Kevin! also, Sonic 3 & Knuckles or Sonic Unleashed are my favorite Sonic games
Sup, Kevin! Statred taking fin 3 days ago and have no sides but today I noticed that the drug causes allergies to me. Something like little rash and a little bit hard breathing. After 1 hour everything went away. I need you help bro, this pill was my last hope to save hair. Should i try to change brand of fin or result will be the same? What can you advise in such a situation?
It's possible it isn't related to finasteride, I would talk to a doctor to be sure. If need be then use dutasteride, it is related but it is a different drug so there is a good chance you're not allergic to it but make sure you talk to a doctor to know for sure it's the finasteride causing it.
If twice weekly .5mg dutasteride hasn’t stopped my loss progression in a year would u recommend upping the frequency to daily or upping the dosage to 2.5 mg twice a week? Or could topical dutasteride perhaps work better for me? Or do I give up lol
I would use 2.5 MG daily or every other day. Topical dutasteride is not a proven product so I wouldn't rely on that. Also, use topical minoxidil in case you aren't already.
Hey Kevin! I am from India and currently 17 years old... I have a lot of body hair (so much leg hair, especially)... People online say this is a sign of high level of DHT in my body....Also, I had so much hair reduction in past two months.. I was NW1 and I am moving into NW2.... I am really worried but I cannot use finasteride due to my age.... Any advice?
It is fine, you are old enough that it is not an issue. Search my channel for 'will using finasteride when you are young hurt your development.' I made a video about it.
Hey Kevin. I am not getting results from minoxidil that I get from my local pharmacy. So I want to buy directly from kirkland. However every product has q comment that states product is fake. Can you give me a trustable link to buy it please?
Do you have access to Target? Their up and up brand minoxidil is what I have relied on for the past 10 years. You could probably buy it online too, can't post a direct link though because it gets flagged as spam.
Hey Kevin, Witcher trainee here. I've been on fin, min and a mix of some spray (hairgen spray with pharmacort and helsinki activator mixed in) that my dermatologist suggested for about 2 months now. I only had some light recession in the temples but i started seeing new small but thick hair from the first month, had a shed during first month too, now at a bit over 2 months shedding has stopped and my hair seems way thicker all around and the temples seem almost completely restored, some of the new hair is a bit shorter but they seem like regular hair and not vellus. My question is should i expect even more regrowth in the first year or should i temper my expectations? Regardless i'm already quite happy with the result and started early thanks to you before things got any worse. Most doctors in my country that are older in age say fin is dangerous and they don't suggest it, thankfully after watching your videos and i found a younger dermatologist that was better informed. Thanks for spreading the truth and good luck with your crunch.
The fact that you're seeing any results this early on is extremely optimistic. Finasteride regrowth results tend to peak by 2 years and then after that it is maintenance, so I think you definitely are going to see more great results. You've got this, choom.
@@haircafekevin Bit of an update, i recently noticed along with the new hair growing on my temples theres also hair growing way beyond where my juvenile hairline used to be. almost on my forehead. They are still small but dont look vellus just shorter (like the temple hair growing). I was careful not to apply minoxidil in that area not sure if that means minoxidil affects an overall area around the spot applied or if that hair will fall off on its own later? If not is there anything i can do like apply less quantity etc? A bit of a weird problem to have, since its usually too little hair, but it does seem concerning and i could not find any info online except hypertrichosis from minoxidil on women, so i thought id ask. Thx in advance.
As I’m doing my research on finasteride one thing i can’t seem to understand is for the people that have “PFS” why don’t they lose their hair after saying all the negative things there going thru after they stopped taking it
@@haircafekevindo you have any opionions on antihistamine sprays and corticosteroid sprays? My brain is plauging me with “nature fallacy” even though I’m dealing with nose congestion and the doctor prescribed them. Thoughts?
Hello! In the video responding to Leo and longevity, you mentioned using Cialis to counter the physical effects of finasteride. However, Cialis has a rare incidence of ototoxicity, which, although rare, can cause a 15 dB decrease in hearing that is irreversible. So, I don't think it's prudent to recommend it. Additionally, Leo mentioned that you can't replace androgen signaling with Cialis, but he didn't explain why if you knwo i would love to knoww. I would love to hear your opinion as a finasteride user and former Cialis user. Cheers!
Hey kevin i've started using minoxidil for the first time today. And i've melted the foam into a dropper container that still had some serioxyl in it. Is this a dumb idea? I didn't want to waste the serioxyl and i had no other dropper.
@@haircafekevin thanks mann! Your video's have saved my hair. 🙏🏻 Also, will the minoxidil foam keep stable for the same expiration date if made it into a liquid? I did put the mixture in the fridge if that helps at all. I warmed it up a little more gently, using 60 degree celcius water.
The worst part about it is the girl who did eventually pick him only picked him by accident. She said she only kept her light on because she thought there was going to be another round, and that she was going to turn it off.
I recently got a test done showing that my testosterone is good at 782 and free test is higher than reference range at 170. Since my free test level is higher than normal does that mean there is more dht or estrogen being converted? Going to ask doctor during followup but wanted your opinion on this result. Would starting finasteride with these results cause anything weird?
Hey Kevin! Longtime fan of the channel. Thanks for all of your help + content! Next week I’m starting my first hair loss treatment! However, I’m uncertain what I should start with. I’m 20 and have a pretty full head of hair but I can see some very small signs of hair loss starting. I wanted to start with a topical treatment. Should I start with fin spray or fin and min spray? What do you think? I think down the line hopefully gt20029 is promising and I can use that. But what can I do right now? Maybe xyons fin treatment? Thanks Kevin!
Hey Kevin I’m so lost right now - been on dutasteride 0.25mg and minoxidil 2.5mg for the past 66 days (2 months 5 days) and I’ve literally gotten so much worse - I initially had a small bald spot at the back and little bit of diffuse thinning that was very early stage staring but now Ive shedded so much hair and the sides are thinner and shedded as well - I used only topical minoxidil for the past year before that and my hair didn’t really improve or do anything so I switch to this and it’s just been a catastrophe??? I’m 17 and just don’t know what to do - some say it’s a shed that happens but even then how long does it last? And when would regrowth even happen
It just sounds like a treatment shed. The reason it is aggressive is because dut is very powerful. You need to be patient though. It can take up to a year to see improvements beyond baseline.
Kevin Mann lets say one doesn't respond well to 5% topical minoxidil what would be the next route. Should he go to 15%minoxidil directly or should he try 10% and then 15% after. Also is 15% minoxidil safe? Let's say i don't want to use oral minox for heart side effects, but isn't using 15% topical minox also dangerous?
Yeah, 15 percent minoxidil works well in people who are poor responders to 5 percent. I wouldn't worry about the cardiovascular side effects because even though the concentration is high, the rate of absorption is extremely low. Check out my video on it. ruclips.net/video/YUNdv782Byo/видео.html
Hey, Kevin why do some studies say that dutasteride takes 1 to 3 or 4 months to build up in serum DHT to 90% serum DHT suppression while Avodart claimed in week one of daily 0.5 dutasteride it went up to 80 or 85% serum DHT suppression? also doesn't finasteride at 1mg daily suppress DHT almost immediately in a week or two, Visual results show up months later but the important thing is how quickly do both meds already start hacking away at DHT?
The 5AR enzyme blocking effect happens very quickly with both drugs, within a few doses. Dutasteride takes a long time to reach steady-state blood levels, literally months, but you get the 5AR blocking effect much more quickly, like within a week.
Hi Kevin. I’ve been on fin for over 1 year. Recently I’ve been under a lot of stress and bad diet etc…noticed my hair started shedding a lot (when I comb, on the towels). Could this be related? I’ve been on fin 1mg every other day and minoxidil daily for over 1 year. Thanks mate
No, it's more likely just a seasonal shed. Stress doesn't cause hair loss like that, check out my video on it because there is a lot of misinformation about stress and hair loss. ruclips.net/video/eLcr9TOJ3G4/видео.html
Hi! I started 3% minoxidil 4wks ago and have shed almost a third of my shoulder length hair. As a girl, this had been hard to hide. When will the shedding stop and is there anything I can do to speed re-growth? Thank you!
The shed means it is working. The weaker telogen hairs are falling out to make way for stronger anagen hairs. There is no way around it, for hair to regrow a shed has to happen. You may want to look into concealers like Toppik if you want to make your look more dense.
Hello Kevin. Thanks to you I got my first finasteride prescription! One question, three supplements I'm taking are vitamin D, zinc, and DIM. Do you think any would have any impact on the efficacy of finasteride or are they fine to take with it? Thank you for the content you produce.
Hi Kevin, I admire all the videos you make. I haven't come across a channel that explains it like you do. I hope you answer my question. I have been using finasteride for 1.5 years. Do you think finasteride will protect my hair for life? 2) Even though I have been using finasteride for 1.5 years, there is still no change in my hair. Should I add minoxyl extra once a week? Should I add dutasteride?
Finasteride will at least maintain what you have indefinitely. If you want to maximize your chances of regrowth though then you should also use minoxidil.
Would you consider a monoclonal antibody for the srd5a2 as a decent therapeutic approach, lesser frequency of administartion, prooven pathway and no brain blood penetration?
Choom what's the best way to mix tretinoin gel with Minoxidil. Should you just put the whole gel in Minoxidil and shake it or what? Also my pharmacy has erythromycin and tretinoin gel mix. That won't be a problem right? Also how should I mix it with my minox. Should I just put the whole gel in the minox and shake it? So basically what's the best way to apply tretinoin gel with Minoxidil?
Question for you haircafe. Does it matter which time of the day you take finasteride. If testosterone is the highest in the morning would it be more beneficial to take it right before bed or early in the morning?
No, it doesn't. Just so long as you are using finasteride on a regular basis then the 5ar enzyme will be under control. The acute fluctuations to androgens throughout the daytime aren't dramatic enough to affect the drug's outcomes.
Does finasteride increase skin sensitivity to light? It’s going to be summer soon and I’m going to be out in the sun a lot (I’ll of course use sunscreen).
Kevin HELP! I'm currently using finasteride 1mg daily + dutasteride 0.5mg once a week, after two years it seems that my hairs are starting to fall again, I don't think it is hair shedding because it's been months and my hairs doesn't seem to have come back. What do you think I should do to be safe again?
Are you minoxing it? Topical minoxidil would be the next step. Also, maybe use 2.5 MG of dutasteride on your dut day instead of 0.5 MG. 0.5 MG only suppresses 10 percent more scalp DHT than finasteride but 2.5 MG suppresses 40 percent more.
@@haircafekevin unfortunately I’ve had side effects from minoxidil (palpitations) so I stopped it. I will try upping the dut! Any other suggestions for a substitute that I can use instead of the minoxidil? Also if in some years the dut will not be enough should I just use dutasteride everyday? At what dosage? Thank you so much for the help 🙏
hi Kevin, im nw 2 but my hair is thinner than before. im on fin but should i use minox if i want to get thick and better hairline? or fin is enough to grow new hair follicles.
Hi Kevin, thanks for all your posts. I’ve been taking Fin for 20 years almost, no issues. But I’m 40 and I swear my hair thinned earlier this year. Could this be the Fin stopping working? Or just age :))) (or could be anxiety…!!) should I get a blood test to check DHT levels? Although I have no baseline to go off….would love your thoughts.
Blood work won't tell you anything as it is scalp DHT that is important, not serum DHT. Finasteride works indefinitely so I think it is more likely a seasonal shed. If you really are convinced you are losing ground though then maybe add dutasteride. I wouldn't recommend dropping a drug that has worked so well for you for so long, so maybe just add duasteride once or twice per week (0.5 or 2.5 MG on the day you use it) and use finasteride on the other days.
I didn’t know a seasonal shed was a thing!! Ok that’s good to know :) this is likely my anxiety…thanks for the notes below will keep in mind and I might take a look into minoxidil if I’m worried, have been meaning to give myself a little more loving there. Thank you very much appreciate the help as always!!
Hi kevin can i ask u doubt i did my my transplant in september its been over 7 months i have good results but around 4 months back i came to canada now i have hair loss but its not bad as im taling dut 0.5 every other day but dandruff is killing my hair do you have suggessions on shampoo and is it ok if i use minoxidil alternatively cuz of dandruff and is there any other stimulant for hair growth?
You can use stemoxydine although it isn't as effective as minoxidil. It probably is just dried residue. Buy a shower comb, you can use it to manually remove the flakes.
hey kevin have you looked at skull foramen calcification as a cause of hair loss. here is a clip from an article of Frederik Hoezel. who was a technician at medical school and he had to remove brain for neurology class. Baldness occurred in persons in whom calcification of the skull bones apparently had not only firmly knitted the cranial sutures but also closed or narrowed various small foramens through which blood vessels pass, most prominently in persons with a luxuriant crop of hair. These blood vessels are mainly veins which normally communicate with the diploic veins in the spongy tissue of the skull bones but which are evidently pinched off by calcification of the foramens.
I don't buy it. Impingement of venous drainage is even more unlikely than impingement of arteries. If there was significant impingement the skin in the scalp would develop edema, which never happens. I don't think there is any research to support his observations.
No, once DHT suppression reaches a certain threshold it will stop 100 percent of hair loss. In the case of finasteride, it stops hair loss in over 90 percent of people.
Hey man love your channel, learned more here than anywhere else. Question- I am getting gynocamastia from .5 my of fin oral daily and when I hop off 3-4 days later my hair thins and falls out. Before i even took fin my hair would never do that. It seems that my hair has become dependent on fjn as it never did that before
If you never took fin your hair would definitely be worse off. Androgenic alopecia can progress rapidly. I'd get back on fin and try a smaller dose, like 0.2 mg. Worst case scenario, get gyno surgery. You can have the doctor remove the entire gland so it doesn't come back.
Kevin, what would be the next action for someone who used dut with min and didnt see good gains in 6 months. Should you add dermarolling and tret with minoxidil or what? Or should you just wait more to see peak results?
6 months is still too soon but the next step would be 2.5 MG of dut. Give it a year though to judge efficacy. These drugs can take up to two years to fully flex their muscles.
@@omerul-farukarslaner8531 I don't recommend derma rolling, period. Tretinoin might be a good adjunct but no matter what you do, 6 months is simply too soon to judge a hair loss stack's efficacy. If you're really losing ground on your current stack (highly unlikely) then stronger 5 AR inhibition is the next best option.
@@haircafekevin thanks kevin for replying. Oral still gives me sides. I tried titrating doses, frequencies etc. I have been a long term user. Currently 37 and am healthy with no excess body weight. Low dose fin lowers my libido. On blood work my free t was at the lower end. Total t is in 450’s.
Topical still works, but I wouldn't use it unless exhausting my options with oral finasteride. If you respond better to topical though then it is fine.
I really hope Tim Pool stumbles across your channel and sees these thumbnails one day.
I hope so too
I'd pay to see his reaction
Kevin I just lost my virginity thanks to you and your videos. Met a girl and she wouldn't stop talking about my hair. Thanks choom ❤
Well done, champ!
@haircafekevin I came across probably the most dramatic meta study about DHT : www.ncbi.nlm.nih.gov/pmc/articles/PMC7308241/
The author claim that DHT utility has been undervalued a lot, and therefore the danger of finasteride and dutasteride vastly underestimate. Do you have any angle on that ?
Amazing thumbnail. I'd pay to go to a museum where it's just these thumbnails displayed.
I wish I was native American, pure native Americans don't go bald
Reddit has recently gon crazy over a supposed result from hmi-115trial after 2month….
Whatever
Whats youre short opinion on pelage? Starting phase 2 trials soon looks somewhat decent, funded by some Ucla scientist.
Always loved the vids on new treatments, eventho we yet dont have a new growth stimulator.
I think I'll hold off on giving my official opinion on PP405, pending a full video on the subject. As far as HMI-115, I don't think we can conclude anything from one leaked result. We don't know if it is representative or an outlier yet.
Bryan selling 1 litre of olive oil for 60 dollars 😭 it better have megadoses of dutasteride in it
😂😂😂😂😂😂
It's criminal, plus I highly doubt it's THAT high quality to justify it, either.
in italy “Clemente” 1L olive oil, which is one of the highest quality commercial olive oil is 14€ or something like $18, and i think its quality is better than the Bryan’s one at 1/3 of the price
@@lorenzodefrancesco4407do you think i can buy this olive oil in a shop in Germany or do i have to buy it directly from Italy to get the „clemente“?
@@lorenzodefrancesco4407 That sounds delicious! I love olive oil.
Bryan Johnson looks like the healthiest terminally ill patient.. He should look at The Rock and just Shave it Bro..
Well he doesn't look that way because he's trying to save his hair
Trying to live forever can wear you down.
@@haircafekevin suggestion on acquiring dutraside?
@@haircafekevinhi mate, i’m norwood 0 but following you just for your thumbnails, and have to admire you gave me big laughs and I am often sharing your video thumbnails with my friends like memes. But i want to ask you seriously, what is your problem with tim pool? İs it bcs he’s hiding his head? can u make one video about him and Ana? You investing so much time on making Memes of this 2 😂😂 thanks chum! :)
Bluetooth transmitter but for hair follicles
Hey Kyle glad to see you here. Hope you cover injectable finasteride soon, the only proven safe method to avoid PFS:
Is injectable finasteride the next leg training?
The “sup chooms” intro is back and so is my dopamine!!
Anyone see the photos of Tim Pool at the summer pool party... still wearing his hat. I would be so happy for him if he got a hair transplant. There is a better way!
It's always hilarious when you use that thumbnail / clip 😂. Especially for us Irish Chooms. It's from an Irish TV Programme and that's Ray Foley (funny irish guy) as the presenter.😅
Definitely one of the most entertaining shows I have seen.
@@haircafekevindo you know of any ways to get dutasteride online?
Watching these I keep thinking Kevin shouldnt keep his ability for deboonking restrained to the hair loss world only. We need you to pwn the dietary supplement scams, lifestyle scams, etc. You are the fist of truth.
Hi Kevin, does minoxidil gains permanent as long as i use it or after enough time i will lose all my gains and return to baseline? if so what is the point of using minoxidil (while using fin )for lifetime if it only works for 4-5 years? not to mention if you stop your hair become even worse. im nw 2 with long hair. hairlineis not that bad but my main problem is density.
Yes, minoxidil works indefinitely. It only loses its efficacy if you use it by itself since it doesn't block dht. If you use it with finasteride it works forever.
I’ve watched all your DUT videos multiple times. They provide great insights into Fin versus DUT, highlighting how DUT may have a similar side effect profile to Fin, if not better. I’m interested in hearing your thoughts on the 75-patient study that examined the reduction in sperm count. As a 22-year-old, this concerns me about potentially having kids in the future.
I'm not sure if you mean this study, academic.oup.com/jcem/article/92/5/1659/2598215 . It showed mild reductions in sperm counts that reversed on stopping therapy. In the majority of men these changes would not affect fertility, but in men with borderline sperm counts to begin with it could. Sperm counts do go back up when stopping treatment in all the studies I have seen, but most of the time it is nothing to worry about.
@@haircafekevin In a study comparing dutasteride vs placebo, 27 healthy men took dutasteride, 0.5 mg, daily for 52 weeks and completed 24 weeks of follow-up.47 At 52 weeks, compared with placebo, dutasteride treatment resulted in a reduction in sperm count, semen volume, and sperm motility (23%, 26%, and 18%, respectively). There were 2 participants in the dutasteride group who had decreases in sperm count that were greater than 90% from baseline at 52 weeks.47 At 24-week follow-up, all semen parameters were within normal range, except for sperm count, which remained decreased at 23% lower than baseline.
@@prav077 If you read the rest of that section of the article, there is a second study where the decrease was not statistically significant at long-term follow-up. Like the article says, the decreases in sperm counts probably are not clinically important in most men and don't affect fertility, but there may some men who have a greater decrease that could cause fertility problems. If this is a concern, the data on 1 mg per day of finasteride might be more reassuring to you, so maybe you should just use finasteride.
@@haircafekevin cool, thanks G!
(theory) Im a big fan of him but I have doubts that Brian Johnson is doing much.
I fear that it`s just his team of doctors simply doing whatever is proven to work (or what they think works)
I`d say other researchers or even the average Redditor on r/supplements is more knowledgable than his team
Exosomes will probably cost hundreds of thousands of eddies at least in the beginning.
We are all ready to sell some pretty sick brain dances, so we can afford it
@@BroMiauu AGA cure is taking so long; I might end up becoming a cyberpsycho.
What's the most effective and safest way to switch from Fin 1mg daily to Dut 2.5mg daily. I've been on Fin 1mg daily for almost 3 months and want to switch to Dut 2.5mg daily.
I am thinking of taking Fin 1mg 5x a week and Dut 2.5mg 2x a week then gradually dropping Fin over the course of a few months (less Fin 1mg, more frequent Dut 2.5mg) and eventually taking only Dut 2.5mg daily.
Would this work or not, or is there a better way to do it? Have you already covered this in a video? If so, send me the video please.
I'd maybe just try it once or twice per week with fin on the other days to see how you respond, and then switch to 2.5 mg daily if you're comfortable with it.
Hey Chooms, hey Kevin !! 👋
I started adding 2.5mg dutasteride on every sunday on top of the 0.5mg dutasteride I take as usual everyday.
My goal is to regrow more hair (basically, despite better regrowth on dutasteride than on finasteride, I still have plenty of miniaturized hair that just won't get thicker....) and my goal is to also regrow those thousands of still miniaturized hair.
I've also been on topical minoxidil for years so you guys know.
I will update on HairCafe's channel in 6 months and in a year to let you guys know how it goes (whether is makes a difference or not).👍
Might even upgrade to 2.5mg dutasteride twice a week on top of dutasteride 0.5mg everyday later if I have to (hair greed I know) .
Wanna do that until GT20029 is out on the market to maximize my regrowth
How did you get it?
Keep us posted!
@@haircafekevinI will keep you guys updated 👍
@@remissiveslavefrom my doctor
Why not just take 2.5mg daily? How old are you?
I don’t know but the dutasteride master race works for me!🔥🔥🔥 now at 1.5 mg
How often do you take dut?
do you take 3 pills every day?
Dut is almost a cure. I’m thinking of hopping onto the master race myself, just scared about It’s effects on sperm counts, I’m 22 almost and that’s also a concern for me.
Fin peasants getting mogged by the dutasteride master race.
Why 1.5 mg vs 0.5 mg?
Guys what finasteride brand you all buy here in USA? Any cheap ways to get?
Generic Proscar. Quarter it for the cheapest finasteride.
Kevin, please make your next thumbnail Jordan Peterson saying to Tim Pool "Sorry. Not beautiful. And no amount of authoritarian tolerance is going to change that."
Hey Kevin
So I had a video call with a well known hair surgeon here in europe this week. After telling him my hairloss history, he suggested the following medical therapy:
- Switching from dutasteride (after 9 years on it) to oral finasteride 1 mg, 1 tablet per day for 1 year.
Reason: My body has most likely built up a tolerance after 9 years of dutasteride. The surgeon has also observed in other patients that the effect of finasteride/dutasteride diminishes after 5-7 years. Tolerance should be resolved with the interruption. He, calls this window therapy.
Have you already heard of fin/dut tolerance and the effetcs after taking a break from it?
I found two videos about this topic on RUclips:
ruclips.net/video/J1cuW86cklw/видео.htmlsi=Y4Mts4eFGf0PP30k
ruclips.net/user/shortsqpW-v2EqNzo?si=J4_PuRBntS4OCm46
What is your take on it and have you adressed it? Thanks for helping out!
Sup Kevin, I’ve been seeing lots of people online vouching for Batana oil for hair loss. Can you make a video giving your opinions on it and comparing to something like rosemary oil maybe. Thanks.
Hey Kevin can you make a video about hairloss supposedly being at an all time high
That's based on very weak observational data from Asia. I've addressed it in some of my Rob English videos. There's no solid evidence at all that this is true.
@@haircafekevin Thank you though I do think hairloss could technically be at an all time high since most countries are aging and older people have less hair
@@haircafekevin I found the video btw
Mr. Kevin Mann can we get some lifting videos like the old times? I lost a little bit motivation for lifting due to an injury. And also kevin, how do you manage injuries while lifting so heavy. I'm 22 and whenever i lift even a 1/3rd of your number i just tear something. I feel like strength is very genetic and i haven't been able to bench 205 even after 3 years training. How do you manage injuries basically and can we get some training footage choom. Maybe a bench press or something.
Seems like dutasteride is the new finasteride
Any idea why there has not been any progress in making synthetic hair? Like, how can we have implanted fake teeth but not implanted fake hair that does not cause infection and other negative side effects? To me it feels like it has to be a more tractable problem than e.g. hair cloning which is cloning an organ and therefore basically final boss of medicine.
SUP CHOOMS, HOW YALL LIVIN? HOPE EVERYTHING IS NOVA AND YOU’RE ALL HAVING A PREEM WEEK
My favorite video intro anywhere on RUclips
Hey Kevin,
really love your content since you were the one convincing me to fight the curse rather than just letting my hair go away. I was wondering if you would do an update on your hair transplantation video.
In your video you are on the side of Fue, however there are several points where I would be interested in your opinion.
-FUT has better growth yields than FUE
-FUT preserves the donor area
There are some papers discussing this. Also the videos of Dr. Bloxham recommend starting with FUT.
What is your stance on this topic? Clearly you were quite succesful doing FUE.
Hi Kevin, hope you are feeling better.
A quick question. Ive seen a commercially available exosome product here in the UK called E50.
When I’ve looked deeper into it, the exosomes are captured/cultured from salmon testes apparently.
I just wonder if there is any data on if all exosomes are created equal, not only in terms of parent progenitor cell type, but also species type.
Can we expect salmon testis derived exosomes to be as effective in hair regrowth as human dermal papilla cells derived exosomes?! My guess is probably not, but that’s complete speculation.
Any thoughts? In truth I am considering trying it out as financially I can take the hit for afew months of experimentation.
Thanks in advance.
Well chooms, after a year and a half on finasteride I am still experiencing hairloss (much slower than it should have been, I'm sure) but still progression wasn't halted. In turn I need advice - anybody know where I can order dut online outside the US? And also, a good place for hair transplants (not in Turkey) with decent prices?
Europe itself like spain has some good ones also fairly cheap compared to the us.
You can get dut from some hairloss surgeons even in the us.
@@migostrigos5436 Spain is interesting will check it out. I'm not from the US but I need an online pharmacy I can buy dut from, in my country only fin is approved for hairloss.
You should check out AnteAGE exosomes . Targeted hair therapy .
Me the 20 yo with dupa, retrograde and regular pattern hl (probably started at 16 yo) has experienced some hairgrowth after 6 months finasteride along my 1.5 nw hairline, so much that it regrew to 1.25 nw, but my dupa continued to worsen after 3 months into fin again, as did my retrograde. Isnt this a sign, that fin is not enough for my dupa and retrograde?
Could just be a seasonal shed. I would give it a few more months to stabilize and if that fails maybe consider 2.5 MG of dutasteride for double finasteride's scalp DHT suppression.
Yo kevin, does hair system cause more hairloss?
I think i will just go for a hair system untill some good cure shows up because i dont want to risk my donor area for a ht at the moment, and ofc ill keep taking fin
Nah, it is completely benign, though you may need to shave the top of your head for a proper fit.
Hey Kevin, hope everything is nova. I was thinking about one thing, if i had a great shedding when I started fin, and i am having a considerable regrowth rn with fin/dut, how likely is it that i will continue to have gains over the next few years? Taking into account that just finasteride was enough to give me some gains, and now I'm on dut 2.5mg daily. Im 21 btw and my hairloss started at early 19.
Your chances of regrowth are very good. In the clinical research, even finasteride alone caused some regrowth in 60 percent of users (the remainder got maintenance), and you're on a stack that is significantly stronger than that.
Peak hair regrowth will likely happen by year 2 but there is research on finasteride showing it continuing to give regrowth even after 10 years so I think you will very likely see continued benefits for many years and you will be able to stop any further hair loss indefinitely.
@@haircafekevin That's good to hear, if I can at least bring my hair to 80% of the density it had, i'll be very happy, and it would save me a lot of grafts for a future HT. I think i'll wait up to 2 years of treatment to decide whether or not i'll need HT.
Just want my 10th grade hair back. Got tretinoin last week, hope it helps. My temples have hair but baby. Hoping maybe i can get them brought back.
Hey Kevin, could you make a video about FOL005?
Yes, it is on my agenda. Unfortunately, I have to do a response video to some moron first so it won't be the next video. I Will try to get it out soon after that though.
@@haircafekevin Thanks Choom. Out of curiosity, who are you responding to?
@@swarthhy Sorry, I have to keep it a secret for now, but it isn't going to be a huge video. Just need to debunk some pro DHT propaganda.
When I got my Hair Transplant done my clinic sent in some of my fair follicles to a lab to harvest and freeze the Sten cells for future use. I wonder if they can separate the exosomes as well
Kevin what is your top resource for researching and choosing a good US-based HT doctor? Can you make a video on this?
Check out the Hair Restoration Network. Great community and resource for information about doctors.
Great vid! also, how frequently would a person need to take 2.5 mg dutasteride along with their normal .5 dose? would it have to be EOD, weekly, or ED?
Hi Kevin, amazing video as always. I was hoping you could make a video about the new study that was published this year in February, about how finasteride down regulated some genes in the hypothalamus of mice and could it be concerning for humans?
Lmfaooo that Bud Light dude thumbnail is too funny
If someone ask you whats the chance of sides on fin, do you say 2% or do you say relative risk is close to 1 so the chances are verry low.
I usually quote the absolute risk, which is risk on drug minus risk on placebo. So that's about 2%, though obviously in some studies it is more, and in some it is less. Overall I consider the risk to be low.
Hey Kevin! I recently got Finasteride perscribed and I'm thinking of microdosing it since my hairloss isn't aggressive and im still young and about a norwood 1.5 or so. I wonder, if I start off with 0.25mg a day lets say, if it works fine, should i keep taking it forever, until lets say a few years later if i start losing gains and experiment with upping it to 0.5mg a day and go on from there? And lets say if i dont lose any ground in a few years, can i take 0.25mg forever? This is just hypothetically speaking, i hope you understand. Thanks man!
Yeah, the dose isn't that much different and it is still effective. If you are more comfortable with 0.25, then go ahead.
interesting stuff, first time I’m hearing about any of it. thanks for the info as always Kevin!
also, Sonic 3 & Knuckles or Sonic Unleashed are my favorite Sonic games
Sup, Kevin! Statred taking fin 3 days ago and have no sides but today I noticed that the drug causes allergies to me. Something like little rash and a little bit hard breathing. After 1 hour everything went away. I need you help bro, this pill was my last hope to save hair. Should i try to change brand of fin or result will be the same? What can you advise in such a situation?
It's possible it isn't related to finasteride, I would talk to a doctor to be sure.
If need be then use dutasteride, it is related but it is a different drug so there is a good chance you're not allergic to it but make sure you talk to a doctor to know for sure it's the finasteride causing it.
If twice weekly .5mg dutasteride hasn’t stopped my loss progression in a year would u recommend upping the frequency to daily or upping the dosage to 2.5 mg twice a week? Or could topical dutasteride perhaps work better for me? Or do I give up lol
I would use 2.5 MG daily or every other day. Topical dutasteride is not a proven product so I wouldn't rely on that.
Also, use topical minoxidil in case you aren't already.
Hey Kevin! I am from India and currently 17 years old... I have a lot of body hair (so much leg hair, especially)... People online say this is a sign of high level of DHT in my body....Also, I had so much hair reduction in past two months.. I was NW1 and I am moving into NW2.... I am really worried but I cannot use finasteride due to my age....
Any advice?
It is fine, you are old enough that it is not an issue. Search my channel for 'will using finasteride when you are young hurt your development.' I made a video about it.
@@haircafekevin thnxs, choom!
Hey Kevin. I am not getting results from minoxidil that I get from my local pharmacy. So I want to buy directly from kirkland. However every product has q comment that states product is fake.
Can you give me a trustable link to buy it please?
Do you have access to Target? Their up and up brand minoxidil is what I have relied on for the past 10 years. You could probably buy it online too, can't post a direct link though because it gets flagged as spam.
What is a "choom?"
it's slang from the game Cyberpunk 2077. essentially "friend"
What are the difference between exosome and regenera activa? Is regenera as effective as exosome?
Hey Kevin, Witcher trainee here. I've been on fin, min and a mix of some spray (hairgen spray with pharmacort and helsinki activator mixed in) that my dermatologist suggested for about 2 months now. I only had some light recession in the temples but i started seeing new small but thick hair from the first month, had a shed during first month too, now at a bit over 2 months shedding has stopped and my hair seems way thicker all around and the temples seem almost completely restored, some of the new hair is a bit shorter but they seem like regular hair and not vellus. My question is should i expect even more regrowth in the first year or should i temper my expectations?
Regardless i'm already quite happy with the result and started early thanks to you before things got any worse. Most doctors in my country that are older in age say fin is dangerous and they don't suggest it, thankfully after watching your videos and i found a younger dermatologist that was better informed. Thanks for spreading the truth and good luck with your crunch.
The fact that you're seeing any results this early on is extremely optimistic. Finasteride regrowth results tend to peak by 2 years and then after that it is maintenance, so I think you definitely are going to see more great results.
You've got this, choom.
@@haircafekevin Bit of an update, i recently noticed along with the new hair growing on my temples theres also hair growing way beyond where my juvenile hairline used to be. almost on my forehead. They are still small but dont look vellus just shorter (like the temple hair growing).
I was careful not to apply minoxidil in that area not sure if that means minoxidil affects an overall area around the spot applied or if that hair will fall off on its own later? If not is there anything i can do like apply less quantity etc?
A bit of a weird problem to have, since its usually too little hair, but it does seem concerning and i could not find any info online except hypertrichosis from minoxidil on women, so i thought id ask. Thx in advance.
As I’m doing my research on finasteride one thing i can’t seem to understand is for the people that have “PFS” why don’t they lose their hair after saying all the negative things there going thru after they stopped taking it
Kev would using antihistamines sprays raise my odds of developing a finasteride allergy??
No, it is benign. Finasteride allergies are exceptionally rare.
@@haircafekevindo you have any opionions on antihistamine sprays and corticosteroid sprays? My brain is plauging me with “nature fallacy” even though I’m dealing with nose congestion and the doctor prescribed them. Thoughts?
@@lbjmvpnzs I'd trust your doctor, they're safe and there is no issue in using them with hair loss drugs, they have no negative interactions.
Hello! In the video responding to Leo and longevity, you mentioned using Cialis to counter the physical effects of finasteride. However, Cialis has a rare incidence of ototoxicity, which, although rare, can cause a 15 dB decrease in hearing that is irreversible. So, I don't think it's prudent to recommend it. Additionally, Leo mentioned that you can't replace androgen signaling with Cialis, but he didn't explain why if you knwo i would love to knoww. I would love to hear your opinion as a finasteride user and former Cialis user. Cheers!
Hey kevin i've started using minoxidil for the first time today. And i've melted the foam into a dropper container that still had some serioxyl in it. Is this a dumb idea? I didn't want to waste the serioxyl and i had no other dropper.
Nah, it's no big deal. You can mix the two, I've done it many times.
@@haircafekevin thanks mann! Your video's have saved my hair. 🙏🏻
Also, will the minoxidil foam keep stable for the same expiration date if made it into a liquid? I did put the mixture in the fridge if that helps at all.
I warmed it up a little more gently, using 60 degree celcius water.
That Take Me Out episode in the thumbnail gives me second-hand PTSD every time I see it
The worst part about it is the girl who did eventually pick him only picked him by accident. She said she only kept her light on because she thought there was going to be another round, and that she was going to turn it off.
@@haircafekevin brutal.
I recently got a test done showing that my testosterone is good at 782 and free test is higher than reference range at 170. Since my free test level is higher than normal does that mean there is more dht or estrogen being converted? Going to ask doctor during followup but wanted your opinion on this result. Would starting finasteride with these results cause anything weird?
Kevin how old are you? 👍
43.
Could you make a video explaining what differentiates hair loss causes in biopsies
Hey Kevin! Longtime fan of the channel. Thanks for all of your help + content! Next week I’m starting my first hair loss treatment! However, I’m uncertain what I should start with. I’m 20 and have a pretty full head of hair but I can see some very small signs of hair loss starting. I wanted to start with a topical treatment. Should I start with fin spray or fin and min spray? What do you think? I think down the line hopefully gt20029 is promising and I can use that. But what can I do right now? Maybe xyons fin treatment? Thanks Kevin!
Nw3 diffuse mpb 17 what do you suggest??
1 MG of finasteride daily and topical minoxidil daily.
@@haircafekevin it will harm development or it just fear
@@InspireMinds-y4r Watch this video.
ruclips.net/video/6zdK_YdE1nM/видео.html
sega CD FTW!
Lunar The Silver Star and Slipheed were my favorites. Oh yeah, and Sol-Feace...that sound track and intro were so epic.
@@haircafekevin and let's not forget Batman Returns!
Hey Kevin I’m so lost right now - been on dutasteride 0.25mg and minoxidil 2.5mg for the past 66 days (2 months 5 days) and I’ve literally gotten so much worse - I initially had a small bald spot at the back and little bit of diffuse thinning that was very early stage staring but now Ive shedded so much hair and the sides are thinner and shedded as well - I used only topical minoxidil for the past year before that and my hair didn’t really improve or do anything so I switch to this and it’s just been a catastrophe??? I’m 17 and just don’t know what to do - some say it’s a shed that happens but even then how long does it last? And when would regrowth even happen
It just sounds like a treatment shed. The reason it is aggressive is because dut is very powerful. You need to be patient though. It can take up to a year to see improvements beyond baseline.
Kevin Mann lets say one doesn't respond well to 5% topical minoxidil what would be the next route. Should he go to 15%minoxidil directly or should he try 10% and then 15% after. Also is 15% minoxidil safe? Let's say i don't want to use oral minox for heart side effects, but isn't using 15% topical minox also dangerous?
Yeah, 15 percent minoxidil works well in people who are poor responders to 5 percent. I wouldn't worry about the cardiovascular side effects because even though the concentration is high, the rate of absorption is extremely low.
Check out my video on it.
ruclips.net/video/YUNdv782Byo/видео.html
Hey, Kevin why do some studies say that dutasteride takes 1 to 3 or 4 months to build up in serum DHT to 90% serum DHT suppression while Avodart claimed in week one of daily 0.5 dutasteride it went up to 80 or 85% serum DHT suppression? also doesn't finasteride at 1mg daily suppress DHT almost immediately in a week or two, Visual results show up months later but the important thing is how quickly do both meds already start hacking away at DHT?
The 5AR enzyme blocking effect happens very quickly with both drugs, within a few doses. Dutasteride takes a long time to reach steady-state blood levels, literally months, but you get the 5AR blocking effect much more quickly, like within a week.
Hi Kevin.
I’ve been on fin for over 1 year. Recently I’ve been under a lot of stress and bad diet etc…noticed my hair started shedding a lot (when I comb, on the towels). Could this be related?
I’ve been on fin 1mg every other day and minoxidil daily for over 1 year. Thanks mate
No, it's more likely just a seasonal shed. Stress doesn't cause hair loss like that, check out my video on it because there is a lot of misinformation about stress and hair loss.
ruclips.net/video/eLcr9TOJ3G4/видео.html
Hi! I started 3% minoxidil 4wks ago and have shed almost a third of my shoulder length hair. As a girl, this had been hard to hide. When will the shedding stop and is there anything I can do to speed re-growth? Thank you!
The shed means it is working. The weaker telogen hairs are falling out to make way for stronger anagen hairs. There is no way around it, for hair to regrow a shed has to happen.
You may want to look into concealers like Toppik if you want to make your look more dense.
Is Revita shampoo as good as people say it is?
No, overpriced garbage. If you want to try ketoconazole shampoo, use 2 percent nizoral 3 times per week.
@@haircafekevin thnx 🙏
Hey Kevin, I’ve been on finasteride for about 2 months now and I’m only losing small thin hairs. Is that a good sign? Thanks!
Yes, it sounds like the weaker telogen hairs are falling out to make way for stronger anagen hairs.
Hello Kevin. Thanks to you I got my first finasteride prescription! One question, three supplements I'm taking are vitamin D, zinc, and DIM. Do you think any would have any impact on the efficacy of finasteride or are they fine to take with it? Thank you for the content you produce.
Nah, they're completely benign. Finasteride doesn't have any negative interactions with supplements or drugs.
you ever watch William Gaunitz's videos on hairloss?
Yeah, the guy's an obvious snake oil salesman.
Hi Kevin, I admire all the videos you make. I haven't come across a channel that explains it like you do. I hope you answer my question. I have been using finasteride for 1.5 years. Do you think finasteride will protect my hair for life? 2) Even though I have been using finasteride for 1.5 years, there is still no change in my hair. Should I add minoxyl extra once a week? Should I add dutasteride?
Finasteride will at least maintain what you have indefinitely. If you want to maximize your chances of regrowth though then you should also use minoxidil.
Hey,
Is there any point for a NW4/NW5 taking finnasteride?
Yes, you'll likely get some regrowth and a NW4/NW5 is still better than a Norwood 7. It also makes a transplant a more viable option in the future.
Would you consider a monoclonal antibody for the srd5a2 as a decent therapeutic approach, lesser frequency of administartion, prooven pathway and no brain blood penetration?
Monoclonal antibodies are too expensive to be practical treatments for hair loss.
Choom what's the best way to mix tretinoin gel with Minoxidil. Should you just put the whole gel in Minoxidil and shake it or what? Also my pharmacy has erythromycin and tretinoin gel mix. That won't be a problem right? Also how should I mix it with my minox. Should I just put the whole gel in the minox and shake it? So basically what's the best way to apply tretinoin gel with Minoxidil?
Thats what I do… with many other things as well
Question for you haircafe. Does it matter which time of the day you take finasteride. If testosterone is the highest in the morning would it be more beneficial to take it right before bed or early in the morning?
No, it doesn't. Just so long as you are using finasteride on a regular basis then the 5ar enzyme will be under control.
The acute fluctuations to androgens throughout the daytime aren't dramatic enough to affect the drug's outcomes.
Hey Kevin!
Is it true that you should stop Finasteride two weeks before a Hairtransplant?
No, I don't think there is any evidence of that. My own doctor didn't make such a suggestion.
Does finasteride increase skin sensitivity to light? It’s going to be summer soon and I’m going to be out in the sun a lot (I’ll of course use sunscreen).
Nope, you're good.
Do you think GT20029 will replace fin or just be another adjunctive treatment?
Most likely an adjunctive therapy. But a very effective one.
Kevin HELP! I'm currently using finasteride 1mg daily + dutasteride 0.5mg once a week, after two years it seems that my hairs are starting to fall again, I don't think it is hair shedding because it's been months and my hairs doesn't seem to have come back. What do you think I should do to be safe again?
Are you minoxing it? Topical minoxidil would be the next step.
Also, maybe use 2.5 MG of dutasteride on your dut day instead of 0.5 MG. 0.5 MG only suppresses 10 percent more scalp DHT than finasteride but 2.5 MG suppresses 40 percent more.
@@haircafekevin unfortunately I’ve had side effects from minoxidil (palpitations) so I stopped it. I will try upping the dut! Any other suggestions for a substitute that I can use instead of the minoxidil? Also if in some years the dut will not be enough should I just use dutasteride everyday? At what dosage? Thank you so much for the help 🙏
Sonic vs Knuckles I and II
hi Kevin, im nw 2 but my hair is thinner than before. im on fin but should i use minox if i want to get thick and better hairline? or fin is enough to grow new hair follicles.
Yeah, I'd go ahead and add minoxidil. You just need to use it once per day and it will increase your chances of regrowth. It's worth it in my opinion.
Hi Kevin, thanks for all your posts. I’ve been taking Fin for 20 years almost, no issues. But I’m 40 and I swear my hair thinned earlier this year. Could this be the Fin stopping working? Or just age :))) (or could be anxiety…!!) should I get a blood test to check DHT levels? Although I have no baseline to go off….would love your thoughts.
Blood work won't tell you anything as it is scalp DHT that is important, not serum DHT. Finasteride works indefinitely so I think it is more likely a seasonal shed.
If you really are convinced you are losing ground though then maybe add dutasteride. I wouldn't recommend dropping a drug that has worked so well for you for so long, so maybe just add duasteride once or twice per week (0.5 or 2.5 MG on the day you use it) and use finasteride on the other days.
I didn’t know a seasonal shed was a thing!! Ok that’s good to know :) this is likely my anxiety…thanks for the notes below will keep in mind and I might take a look into minoxidil if I’m worried, have been meaning to give myself a little more loving there. Thank you very much appreciate the help as always!!
Sonic adventure 2 battle is my favorite sonic game
I prefer the first Sonic Adventure on the Dreamcast because I loved the exploration and open world. Sequel was good too.
Hi kevin there are recently published papers which show that finasteride causes gut dysbiosis is that true ?
I'm skeptical of this, but I think it is important enough a topic that I will add it to my list of video topics to cover soon.
Is it possible to go from norwood 2 to norwood 1 with finasteride and minoxidil?
Yes.
Hi kevin can i ask u doubt i did my my transplant in september its been over 7 months i have good results but around 4 months back i came to canada now i have hair loss but its not bad as im taling dut 0.5 every other day but dandruff is killing my hair do you have suggessions on shampoo and is it ok if i use minoxidil alternatively cuz of dandruff and is there any other stimulant for hair growth?
You can use stemoxydine although it isn't as effective as minoxidil. It probably is just dried residue.
Buy a shower comb, you can use it to manually remove the flakes.
hey kevin have you looked at skull foramen calcification as a cause of hair loss. here is a clip from an article of Frederik Hoezel. who was a technician at medical school and he had to remove brain for neurology class.
Baldness occurred in persons in whom calcification of the skull bones apparently had not only firmly knitted the cranial sutures but also closed or narrowed various small foramens through which blood vessels pass, most prominently in persons with a luxuriant crop of hair. These blood vessels are mainly veins which normally communicate with the diploic veins in the spongy tissue of the skull bones but which are evidently pinched off by calcification of the foramens.
I don't buy it. Impingement of venous drainage is even more unlikely than impingement of arteries. If there was significant impingement the skin in the scalp would develop edema, which never happens. I don't think there is any research to support his observations.
@@haircafekevin but have we ever looked under the scalp of people who have hair and dont? To compare and see what is the issue?
Does aspartame from zero sugar drinks cause hair loss and trigger shedding?
No, it is benign.
What would you say in your opinion is the most nuclear hair loss stack one could take?
2.5 mg of dutasteride, topical minoxidil mixed with tretinoin gel.
Norwood reaper has no chance.
My hair looks worse than ever since two months on dut. How long will it take to recover from this treatment shed?
Likely at least a few more months. The extreme shedding means it is working. Everything you'v lost will come back stronger.
@@haircafekevin this is reassuring. Thank you so much.
Hey . i have a question. If finasteride lowers scalps DHT by 60% for example, it means that your hairloss slows down by 60% ? Thats how it works?
No, once DHT suppression reaches a certain threshold it will stop 100 percent of hair loss. In the case of finasteride, it stops hair loss in over 90 percent of people.
@@haircafekevin but that's usually for the first 3 years?
@@ar1482 No, indefinitely. Check out my video titled "Why finasteride stops hair loss forever." I talk about it there.
Hey man love your channel, learned more here than anywhere else. Question- I am getting gynocamastia from .5 my of fin oral daily and when I hop off 3-4 days later my hair thins and falls out. Before i even took fin my hair would never do that. It seems that my hair has become dependent on fjn as it never did that before
If you never took fin your hair would definitely be worse off. Androgenic alopecia can progress rapidly.
I'd get back on fin and try a smaller dose, like 0.2 mg.
Worst case scenario, get gyno surgery. You can have the doctor remove the entire gland so it doesn't come back.
@@haircafekevin bro you are so awesome thanks for responding and the advice I appreciate it greatly.
@@haircafekevin do you do paid consultations?
Can finasteride stop hairloss forever? maybe you have a video on it
Sure do, choom! Right here.
ruclips.net/video/LsF9MwIM_AM/видео.html
@@haircafekevin thank you
Kevin, what would be the next action for someone who used dut with min and didnt see good gains in 6 months. Should you add dermarolling and tret with minoxidil or what? Or should you just wait more to see peak results?
6 months is still too soon but the next step would be 2.5 MG of dut. Give it a year though to judge efficacy. These drugs can take up to two years to fully flex their muscles.
@@haircafekevinSo you don't recommend tret or dermarolling? Should I just continue with 0.5mg dut and 1mg min?
@@omerul-farukarslaner8531 I don't recommend derma rolling, period. Tretinoin might be a good adjunct but no matter what you do, 6 months is simply too soon to judge a hair loss stack's efficacy.
If you're really losing ground on your current stack (highly unlikely) then stronger 5 AR inhibition is the next best option.
Hey Kevin , so finastride won’t make me gain weight , right ?
No, it won't.
@@haircafekevin thanks brotha man
hey kevin what happens if you take both oral dutasteride and oral finasteride daily?
They don't stack, so same as dut daily.
@@haircafekevin what does that mean?
@@PartyVibez1 It means the results will be the same as if you were taking dut daily only.
Kevin if I’m trying to grow out my hair really long do I need to get trims?
Nah, just grow it out.
@@haircafekevin what if I have or get split ends?
Hey Kevin, what you think about topical brands like xyon? Your reply is appreciated? Thanks
Overpriced and overrated. Just stick with oral finasteride and titrate down if you get sides.
@@haircafekevin thanks kevin for replying. Oral still gives me sides. I tried titrating doses, frequencies etc. I have been a long term user. Currently 37 and am healthy with no excess body weight. Low dose fin lowers my libido. On blood work my free t was at the lower end. Total t is in 450’s.
Topical still works, but I wouldn't use it unless exhausting my options with oral finasteride.
If you respond better to topical though then it is fine.
Thanks Kevin. I loved the effect of oral unfortunately ended up with sides. You do great work. Thanks! I hope xyon works. That’s how desperate I am