ജീവന് ഭീഷണിയാകുന്ന പാർക്കിൻസൺ രോഗം Dr. Sreeram Prasad A V | Rajagiri | Parkinson's

Dr. Sreeram Prasad A V
Senior Consultant - Neurology
Parkinson's disease is a progressive neurodegenerative disorder that affects movement control. It primarily impacts dopamine-producing neurons in the substantia nigra, a region of the brain. Here are key aspects of Parkinson's disease:
Symptoms
Motor Symptoms:
Tremor: Shaking, usually starting in the hands or fingers.
Bradykinesia: Slowness of movement.
Muscle rigidity: Stiffness in the limbs or trunk.
Postural instability: Impaired balance and coordination.
Non-Motor Symptoms:
Cognitive changes: Memory problems, difficulty concentrating.
Mood disorders: Depression, anxiety.
Sleep disturbances: Insomnia, REM sleep behavior disorder.
Autonomic dysfunction: Problems with blood pressure regulation, bowel, and bladder function.
Causes and Risk Factors
Genetics: Certain gene mutations are linked to Parkinson's.
Environmental Factors: Exposure to toxins like pesticides may increase risk.
Age: Risk increases with age, most common in people over 60.
Sex: Men are more likely to develop Parkinson's than women.
Diagnosis
Clinical Evaluation: Diagnosis is primarily based on medical history and neurological examination.
Imaging: MRI or DaTscan may be used to rule out other conditions.
Response to Medication: Improvement with Parkinson's medications can support the diagnosis.
Treatment
Medications:
Levodopa/Carbidopa: Most effective treatment, replenishes dopamine.
Dopamine agonists: Mimic dopamine effects in the brain.
MAO-B inhibitors: Help prevent breakdown of brain dopamine.
COMT inhibitors: Prolong the effect of Levodopa.
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[@GauthamiSNair]

Cute anchor😍nice information toooo💪

[@DoctorLiveMedia]

Thank You

[@devivandana7612]

Very informative

[@DoctorLiveMedia]

Thank You