Lol how did u get into second year without knowing that . Proud of you still, medicine is a frriggin rolllercoaster, theres things that still to this day may confuse you. Keep it going
I am a student of B.Pharm from India. All of your videos are totally understandable and very helpful for me. Thank you sir, for your efforts.❤️❤️ I search your video of related topic most of the time, before studying any chapter of pharmacology. Once again thanks...
Thank you so much!!! Its because of your videos that I passed my first semester of med school! and now I religiously use ur videos to revise for my next semester. Keep up the good work :)
I have to say, your knowledge, drawings and videos are AMAZING!! and they have literally saved my (Biology) life!! I've watched so many of your videos and the have helped me pass the most difficult class in my University life. My professor doesn't lecture AT ALL and we have to learn a whack load of new information every week and have a verbal lab evaluation and a test on new material every week - plus Midterm and Final of course, so you can imagine that it is difficult to learn something that seemingly comes across as foreign at first, really fast and every single week. THANK YOU !!!! By the way, do you sell your drawings? I would LOVE to have some on my wall......
Hey Armando! Super video, you are the hero of the poor science and med students from all over the world :) One question/correction only: As far as I know, the cells that you have named should be extraglomerular mesengial cells. However, the juxtaglomerular cells that produce renin are the differentiated epithelial cells of the afferent arterial (their muscular layer on tunica media is different). Please contribute, guys :)
Exactly. There's a confusion here. It's the INCREASE in sodium content (tubule) that triggers renin secretion (renin will "correct this loss" and elevate pressure)
Thanks for making those videos! Just one small thing: from what I've learned in University the macula densa cells are (although right at the border to the distal convoluted tube) still part of the thick ascending limb of the loop of Henle.
Thanks. We can have a healthier life just by knowing our body. The work of diabetes and renin-ang system should be in our school book ! In that way we cannot blame the lack of knowledge for our misfortune .
Excellent video, very well explained, (better explained than my phd teacher who just confuses me) I have a question, are angeotensinogen and angeotensin 1 and 2 all hormones ?
Armando, your videos are priceless and always worth watching. If I had one comment to suggest improvement it would be to polish up the language you use to make sure it is always accurate, e.g. convulated isn't a word and actually using the correct word, convoluted, helps to remember it because the tubule is indeed a convoluted shape. Aside from this minor point, this is another superb video, thank you.
Great video, but I can't quite seem to get my head around the fact that you state BP is the main contributing effect of RAAS-activation. To my understanding, this system is mainly a response to decreased effective circulatory volume (Boron & Boulpaep). That sympathetic increase in BP would confer decreased effective circulatory volume seems contradictory to me. I might have gotten it all wrong from the start, but if you are able to clear this up for me it would be greatly appreciated!
can you explain how a decrease in [Na] in the DCT/ macula densa causes renin release, because renin eventually causes an increase in aldosterone and Na reabsorption which would lead to a further decrease in Na in the DCT, this would appear to be a positive feedback loop but I don't think it works like that
Mr. Hasudungan do you have a video that explains the release of erthropoietin or EPO also known as hematopoietin from the kidneys. I enjoy your videos.
So both baroreceptors in the afferent arteriole AND in the aorta can stimulate renin release by detecting changes in blood pressure? Is my understanding correct?
Great video! i have been using your kidney and nephro videos to help fellow pharmacy students to prepare for volunteering at a camp for kids with CKD through the NKF. Thanks for your work.... any chance you can upload the google image??
I don't feel I've ever understood how the RAAS system becomes chronically and pathologically activated. The two big mechanisms mentioned here seem to be renal hypoperfusion and hyponatremia. In either case, it seems like it would be quite a bad idea to inhibit the RAAS system with an ACE-I or ARB. Still quite confused.
In dct, macula densa cells (chemoreceptors) detect the low [Na+] and [Cl-] (from filtered blood) which stimulates the juxtaglomerular cells to produce/secrete more renin into the blood.
the illustration is great but you're kind of wrong with the location of ACE. It's on the membranes of pulmonary vessels not in the alveoli. source: UWorld STEP1
4 years of medical school, and only today i finally understand what the macula densa and Juxtaglomerular Apparatus finally is
Thank you so much man!
Dude, I feel that big time. I'm still an undergrad, but I finally got a grasp on the juxtaglomerular apparatus today in lecture, feels satisfying :)
This we can't expect from our textbooks
Lol how did u get into second year without knowing that . Proud of you still, medicine is a frriggin rolllercoaster, theres things that still to this day may confuse you. Keep it going
its joever@@eugenioasanchezperez1406
I almost think every medical student lowkey knows who Armando Hasudungan is
Of course :)
Well don't they?
*highkey ✌💖
I still have great regards for this teacher( M. Ashraf.... consultant emergency medicine...
India...
I am a student of B.Pharm from India. All of your videos are totally understandable and very helpful for me. Thank you sir, for your efforts.❤️❤️ I search your video of related topic most of the time, before studying any chapter of pharmacology. Once again thanks...
Should be Titled "Fantastic Drawings of Anatomical Guts & Explaining the Near Unexplainable in Simple Terms" Bravo my friend!
Thank you so much!!! Its because of your videos that I passed my first semester of med school! and now I religiously use ur videos to revise for my next semester. Keep up the good work :)
'And I'm not gonna talk about it in this video' - damn, what a tease!
The drawing was soooo soothing 🥺
Explanation + drawings = perfect
You are excellent, per usual.
Keep in mind:
Renin (ree-nin) = enzyme for RAAS
Ren-nin (ren-in) = enzyme for making cheese
;)
I have to say, your knowledge, drawings and videos are AMAZING!! and they have literally saved my (Biology) life!! I've watched so many of your videos and the have helped me pass the most difficult class in my University life. My professor doesn't lecture AT ALL and we have to learn a whack load of new information every week and have a verbal lab evaluation and a test on new material every week - plus Midterm and Final of course, so you can imagine that it is difficult to learn something that seemingly comes across as foreign at first, really fast and every single week. THANK YOU !!!! By the way, do you sell your drawings? I would LOVE to have some on my wall......
hello 1000cher ,have an 🍨 icecream sometimes ,you been studying , a lot
thanks for helping med students all over the world!!
liked that subtle "substance, well, substrate". That means you put interest at accuracy. Great videos, so much talent.
I love your videos super much! Thank you for helping me and all other students. You made A&P so easy and fun!
It is simple easy with more illustrated, thank you so much for your work
Hey Armando! Super video, you are the hero of the poor science and med students from all over the world :)
One question/correction only: As far as I know, the cells that you have named should be extraglomerular mesengial cells. However, the juxtaglomerular cells that produce renin are the differentiated epithelial cells of the afferent arterial (their muscular layer on tunica media is different). Please contribute, guys :)
Sen bir ineksin
yess ure right
Exactly. There's a confusion here. It's the INCREASE in sodium content (tubule) that triggers renin secretion (renin will "correct this loss" and elevate pressure)
Excellent video. Great illustrations. Helped me to understand the system more extensively. Thank you.
damn homie u can draw
just a tip: your handwriting is not legible.
Excellent explanation and pictures! Really very well done. Thanks
thanks all of your video really helpful.for my endocrinology mid term and final term
I really enjoy watching your videos. Thank you for doing this!
thanks that was helpful. i have a test on urinary tomorrow and i have been struggling with renin. thanks
This helped me ALOT. Thank you so much! I love your videos.
your drawings are sooooooo helpful!! thank you!!!
thank you. armando. your videos are the best. thanks for the effort you put into them.
I am very happy to see your video as i read it in text book forty years back.
I'm not even a medical student, just here trying to solve my blood pressure problems lol
This has helped me sooooo much as a student!! thankyou!
love your drawings, thanks millions - so helpful
It’s brain reliever❤️
absolutely amazing and clear thank you!
Appreciate your extremely nice video. Everything was delivered ❤❤❤
Thank you so much 🤗
Thanks so much for these videos! You are helping get through school.
UROOOONNNN XD you saved me in my endocrinology class thank you!
This was so so helpful! Thank you so much for making this video!!!
An excellent video!!!
Congratulations.
This is an amazing channel!!!
Thank you!
Thank you so much , its very helpful
Thanks for making those videos! Just one small thing: from what I've learned in University the macula densa cells are (although right at the border to the distal convoluted tube) still part of the thick ascending limb of the loop of Henle.
*At the junctn of DCT and thick part of ascending Loop of Henle
You are videos are so helpful
Thanks a lot this really helped me 🙏
Thanks. We can have a healthier life just by knowing our body. The work of diabetes and renin-ang system should be in our school book ! In that way we cannot blame the lack of knowledge for our misfortune .
It is
Whoa ur diagrams are brilliant!!👍
Thanks for sharing the video and drawing with me #PicassoArtwork # priceless
Excellent video, very well explained, (better explained than my phd teacher who just confuses me) I have a question, are angeotensinogen and angeotensin 1 and 2 all hormones ?
Congrats for this video! 👏🏽👏🏽👏🏽👏🏽
Amazing as always
Armando, your videos are priceless and always worth watching. If I had one comment to suggest improvement it would be to polish up the language you use to make sure it is always accurate, e.g. convulated isn't a word and actually using the correct word, convoluted, helps to remember it because the tubule is indeed a convoluted shape. Aside from this minor point, this is another superb video, thank you.
I suggest you listen to Dr. Lecter, Armando.
Great video, but I can't quite seem to get my head around the fact that you state BP is the main contributing effect of RAAS-activation. To my understanding, this system is mainly a response to decreased effective circulatory volume (Boron & Boulpaep). That sympathetic increase in BP would confer decreased effective circulatory volume seems contradictory to me.
I might have gotten it all wrong from the start, but if you are able to clear this up for me it would be greatly appreciated!
Sir pls make video on creatinine synthesis and how phenylacetate and banzoate effect creatinine and urea formation.thanks a lot for brief explanation
I really enjoy your videos thank you so much :)
Thank you very much! GREAT JOB
YOU-RINE!
Thanks armando you are very good
excellent as usual ..many thanks
whoever it's very usefull...and thank u so much....and need more☺☺☺☺☺
You rock ! Thank you for being so clear
can you explain how a decrease in [Na] in the DCT/ macula densa causes renin release, because renin eventually causes an increase in aldosterone and Na reabsorption which would lead to a further decrease in Na in the DCT, this would appear to be a positive feedback loop but I don't think it works like that
Mr. Hasudungan do you have a video that explains the release of erthropoietin or EPO also known as hematopoietin from the kidneys. I enjoy your videos.
I am not being overcritical. That drawing is amazing. I wish.
So great, thank you for your video
Sir , can you put a video on action and resting potential of nerve impulses please
thanks armando
Excellent drawing 👍👌👌
Such amazing diagrams, does he use any
app or make it on paper
🧠 TEST YOUR KNOWLEDGE FROM THIS LECTURE! ✅
youmakr.ai/test-playground/questionnaire/673d4644859b9c170836efaa
So both baroreceptors in the afferent arteriole AND in the aorta can stimulate renin release by detecting changes in blood pressure? Is my understanding correct?
Your videos are always helpful sir :)
Tq sooooooo much sir 🙏❤️
thank you so much! your videos are cool 😙😙😙
Great video! i have been using your kidney and nephro videos to help fellow pharmacy students to prepare for volunteering at a camp for kids with CKD through the NKF. Thanks for your work.... any chance you can upload the google image??
I don't feel I've ever understood how the RAAS system becomes chronically and pathologically activated. The two big mechanisms mentioned here seem to be renal hypoperfusion and hyponatremia. In either case, it seems like it would be quite a bad idea to inhibit the RAAS system with an ACE-I or ARB. Still quite confused.
Pure genius! Thank you for what you do!
5:42 passing through dct means to blood or into collecting duct?
In dct, macula densa cells (chemoreceptors) detect the low [Na+] and [Cl-] (from filtered blood) which stimulates the juxtaglomerular cells to produce/secrete more renin into the blood.
This was beautiful
Thank you
the angiotensin converting enzyme is located in endothelial cells in lung capillaries
THANKYOU SO MUCH SIR...ALLAH BLESS YOU :)
thanx a lot!
you're great man thank you so much
GREAT, GREAT AS USUAL. THANKS.
Thank you!!
Thanks a lot for that explain!
Besides, I really loved your drawing :)
there is loop of henle which is essentially a... loop.
That's it. This is the simplicity I want in medicine.
Dude you are the best thank you
the illustration is great but you're kind of wrong with the location of ACE. It's on the membranes of pulmonary vessels not in the alveoli.
source: UWorld STEP1
Hey can we get these flow charts??
Make a book and make it available on Amazon 🙏🙏
Hola Armando ,were can I get some of this drawings ??
Gorgeous!
Very nice 👍
I just can't thank u enough 💖✌💫💫💫💫
are there pdfs of the final picture we can print?
I'd love one too. His drawing is awesome
Thank u sir
excellent
Fab-you-lous❤❤... Thanks
Now you are my Master :D
thankyou
you man are awesome :D i love your work :) keep on the hard work and thank you. best of luck :D
Awesome
thanx s lot
ممتاز فعلا
فين رابط الصور بتاعة الفديو بقي :) ؟
Macula densa should be in thick ascending tubule not distal convoluted tubule
no they aren't