The fact that this video covered all of diuretics in an easy way to understand is amazing compared to 4 hours of lecture time that made no sense. Much appreciated video.
I teach pharm and I really like the amount of time you obviously spend on organizing the information visually. When I cover diuretics I emphasize the hypokalemia/hyperkalemia effects of the drug classes a bit more and mention aquaporins, but I love the level of detail you've got here in each section. You've organized it in such a way as to not be overwhelming to the beginning student. You should consider making a book! :-)
TaiChiKnees None of this is on the PTCB exam- just help me pass that. I am researching this because I was taking lisinopril due to having natural high bloodpressure 140 over 95 with a 101 pulse rate and I want everyone to know that lisinopril: ACE inhibitor/duretic made me pass out twice, so I was switched to metoprolol: Beta Blocker..... With my personal self research: I'd like to say that I believe Beta Blockers should be taken strictly on a prn basis since the prolonged use can cause a stroke once you wing off.... I'd like to understand why my doctor believes I should take this for the rest of my life causing a death sentence? When it should be a prn drug? And another thing. Why did a pharmacy tell my insurance company that I was taking a generic brand named drug whenever I was scripted the brand name? The PTCB exam has hospital software questions--- That should be considered when teaching because they want Technicians to know what Nurses should know.
+TaiChiKnees I am responding to your comment eventhough it wasn't written to me but since you teach pharm i can't pass by and not bring this up to you. Bassically it's about diuretics efficacy in managment of decompensate heart failure, there is no doubt they are effective in treating few acute states and CHF to some extent. However treating decompensated HF is going to do nothing, fluids will accumulate in the body no matter what, the amount you excrete is just going to get back to circulatory system from instersticium and if you stop drinking fluids you're gonna die from dehydration. What my question is, can it be said that they are ineffective in treating decompensated heart failure in the long run?
This was great, thanks, I been tryin to find out about "thyroid wellness for dogs" for a while now, and I think this has helped. You ever tried - Yannabarn Vanish Thyroid - (Have a quick look on google cant remember the place now ) ? Ive heard some extraordinary things about it and my mate got excellent success with it.
To be honest i wont be surprised if other textbooks use either of these cells as the major site of aldosterone function. What I learnt from my lecture was that aldosterone elicits its function on the intercalated cells, but than again its probably both.
You are right i could've made this video better by adding the K and H pumps in. I just felt that I wanted to get the point through, how these diuretics aim to decrease BP. Ill add those comments on the video soon, but worried it might confuse some people. cheers
I've been a nurse 11 years and had stumbled upon these videos on one of my late "need to refresh myself since i'm awake" nights. This information is extremely helpful especially when you are working with patients who ask a ton of questions about why, what and the need for their "water pills". Thank you.
I can’t remember the last time I commented on a video, honestly don’t even think I ever have. But sir, you deserve all the praise for your illustrations and explanations. I am so happy to have found your channel !!!
Awesome stuff armando. I used these videos since the beginning of my nursing journey, the pre-requisites, and have used them throughout. Now I am an ER RN. With these videos and the mobile app Nclex Nursing Tools, I have rocked pharm. Thanks again brother, cheers.
One way to remember things is to Visualize them. That's what happened here. Every bit is clearly explained and organised. Recommend watching. Thank you Armando Hasudungan :) Thumbs!
Hey Armando, I'm a student Paramedic at Sheffield Hallam University UK. I wanted you to know just how much I swear by your videos. Some of this stuff is really difficult for me to understand and text books drive me crazy. Great work. Right now I am looking at thiazide diuretics and the implications on left ventricular failure. Thanks to you I think doing relatively well.
Actually after watching all these videos i don't really understand why do you guys hitting unlike button ................. even if u don't like these videos ,,,, why can't i just leave ????? please don't do this and learn to encourage them ..................
Hey, I don't know whether this has been pointed out before, but urea has nothing to do with uric acid (urea cannot convert into urate/uric acid). Therefore, the information regarding the thiazide diuretics isn't strictly true, as thiazides promote the reabsorption of urate (not urea) at the distal convoluted tubule and so you end up with hyperuricaemia which can then lead to gout. I just wanted to point this out as it can lead to confusion. Otherwise an excellent video for learning the different classes and MOAs of diuretic drugs.
That "WHAT!" at 14:43 sounded like either 1) Armando just made a mistake and is extremely pissed with himself 2) Armando is amazed at the abilities of spironolactone
Thank you so much! The best point in your explanation that you never get sick of repeating what is normally happening and THEN telling us what happens diffrently, it keeps reminding us and allowing us to compare the difference between the abnormal(in case of diseases) Or the pharmacological effect If our doctors would bother to spare a couple of minutes to reminds of the normal during their explanation rather than "trusting" that the other (physiology/anatomy/histology) has done it before them, i won't be half as lost as i usually am, and my circulating problem is that when i get lost i lose interest and i tend to zone out the rest of the lecture.... Thus I am extremely thankful for your videos, Thank you!
these compounds are used commonly in my sport, and I now have an incredible understanding of their actions------thank you so much for sharing what must have been years of study
Thanks for all of the hard work you are doing, it is greatly appreciated by everyone. I believe you should make this artwork into a PDF document and post it on a website for students to download. While the video is great, the notes would help us study for exams, etc. without having to be at a computer. Thanks again.
for Thiazide, I think it is not so much that the Thiazides inhibits the excretion of Calcium, but rather, while inhibiting the NaCl cotransport, it reduces the intracellular Sodium concentration, promoting the NaCa2 transporter (on the blood side) to give to the cell sodium in exchange for Ca2. Therefore, calcium in the lumen will enter the cell and exit via the NaCa2 transporter into the blood.
Raissa Canales he didn't mention that in thiazide it will cause hypocalcemia he only mentioned that calcium will be not be reabsorbed in which it won't be excreted in the urine causing increase in ca in plasma. replay the video.
sir i'm a pharm d student and you are like my cology teacher because i almost studied every topic from here..plz sir at the end show the whole page so that we can take screen shot as it will help ous to revise quickly ..can you plz share the pic of the whole sheet plz plz plz
I also learned that ADH and Aldosterone both work on principal cells. But I do know that Aldosterone DOES stimulate the H+ ATPASE on alpha intercalated cells. (alpha = secrete H+, beta = secrete HCO3-) I was surprised I didn't see the K+/H+ antiport and the H+ ATPase in the alpha-intercalated cells. Considering that renal distal tubular acidosis causes hypokalemia as well. Using diuretics with that would just worsen it considering loop and thiazide diuretics are K+ wasting.
Hi I really like your simple and precise way of explaining concepts! Please continue making such beautiful and helpful videos. P.S."Symptomer" @ 2:42 should be corrected to "symporter"
This video is really amazing ^__^ Thank you so much for helping me understand the way diuretics work 👍 There is one teeny tiny thing though : You talk waaay too fast and sometimes I find it hard to keep up while taking notes , so can you please slow it down a little bit 😊
A great video!, but just one thing, at 14:10 you are stating that spironolactone (aldosterone inhibitors) are working on intercalated cells, but in fact spironolactone (aldosterone inhibitors) - their target cells are Principle cells, as well as aldosterone - his main target cells are as well Principle cells, but again, a great video thank you!
Im a pharmacy student and this was 1000x more helpful than any of the classes or lectures I've been to. Truly grateful THANK YOU!!
ruclips.net/video/YubDzhN5IRE/видео.html
The fact that this video covered all of diuretics in an easy way to understand is amazing compared to 4 hours of lecture time that made no sense. Much appreciated video.
I'm a third year medical student and always use your videos to scrub up on the basics before starting a new firm, you do an excellent job, thank you!
any updates doc
I teach pharm and I really like the amount of time you obviously spend on organizing the information visually. When I cover diuretics I emphasize the hypokalemia/hyperkalemia effects of the drug classes a bit more and mention aquaporins, but I love the level of detail you've got here in each section. You've organized it in such a way as to not be overwhelming to the beginning student. You should consider making a book! :-)
TaiChiKnees thanks!
TaiChiKnees None of this is on the PTCB exam- just help me pass that. I am researching this because I was taking lisinopril due to having natural high bloodpressure 140 over 95 with a 101 pulse rate and I want everyone to know that lisinopril: ACE inhibitor/duretic made me pass out twice, so I was switched to metoprolol: Beta Blocker.....
With my personal self research: I'd like to say that I believe Beta Blockers should be taken strictly on a prn basis since the prolonged use can cause a stroke once you wing off....
I'd like to understand why my doctor believes I should take this for the rest of my life causing a death sentence? When it should be a prn drug? And another thing. Why did a pharmacy tell my insurance company that I was taking a generic brand named drug whenever I was scripted the brand name?
The PTCB exam has hospital software questions--- That should be considered when teaching because they want Technicians to know what Nurses should know.
+TaiChiKnees I am responding to your comment eventhough it wasn't written to me but since you teach pharm i can't pass by and not bring this up to you.
Bassically it's about diuretics efficacy in managment of decompensate heart failure, there is no doubt they are effective in treating few acute states and CHF to some extent. However treating decompensated HF is going to do nothing, fluids will accumulate in the body no matter what, the amount you excrete is just going to get back to circulatory system from instersticium and if you stop drinking fluids you're gonna die from dehydration. What my question is, can it be said that they are ineffective in treating decompensated heart failure in the long run?
This was great, thanks, I been tryin to find out about "thyroid wellness for dogs" for a while now, and I think this has helped. You ever tried - Yannabarn Vanish Thyroid - (Have a quick look on google cant remember the place now ) ? Ive heard some extraordinary things about it and my mate got excellent success with it.
TaiChiKnees i
To be honest i wont be surprised if other textbooks use either of these cells as the major site of aldosterone function.
What I learnt from my lecture was that aldosterone elicits its function on the intercalated cells, but than again its probably both.
you consume lots of time to help us beautifully understanding various medical basics in short time ! & saving our time
A huge Thanks !
You are right i could've made this video better by adding the K and H pumps in. I just felt that I wanted to get the point through, how these diuretics aim to decrease BP. Ill add those comments on the video soon, but worried it might confuse some people.
cheers
I've been a nurse 11 years and had stumbled upon these videos on one of my late "need to refresh myself since i'm awake" nights. This information is extremely helpful especially when you are working with patients who ask a ton of questions about why, what and the need for their "water pills". Thank you.
ruclips.net/video/YubDzhN5IRE/видео.html
ruclips.net/video/YubDzhN5IRE/видео.html
you always save my life when it comes to studying for tests! thanks a lot!!
ruclips.net/video/YubDzhN5IRE/видео.html
I can’t remember the last time I commented on a video, honestly don’t even think I ever have. But sir, you deserve all the praise for your illustrations and explanations. I am so happy to have found your channel !!!
ruclips.net/video/YubDzhN5IRE/видео.html
Awesome stuff armando. I used these videos since the beginning of my nursing journey, the pre-requisites, and have used them throughout. Now I am an ER RN. With these videos and the mobile app Nclex Nursing Tools, I have rocked pharm. Thanks again brother, cheers.
I LITERALLY SHOULD PAY YOU TO BE MY PROFESSOR, CAUSE THE ONES I HAVE, ARENT CUTTING IT
ruclips.net/video/_cV_6deVJSk/видео.html
One way to remember things is to Visualize them. That's what happened here. Every bit is clearly explained and organised. Recommend watching. Thank you Armando Hasudungan :) Thumbs!
If you keep doing these videos all medical disciplines then YOU are the future of medical education !
great explanation SIR 👍👍
ruclips.net/video/YubDzhN5IRE/видео.html
@@drnajeebali425ruclips.net/video/YubDzhN5IRE/видео.html
Hey Armando, I'm a student Paramedic at Sheffield Hallam University UK. I wanted you to know just how much I swear by your videos. Some of this stuff is really difficult for me to understand and text books drive me crazy. Great work. Right now I am looking at thiazide diuretics and the implications on left ventricular failure. Thanks to you I think doing relatively well.
I wish I can see the map as a whole in the end so I can memorize it easily like a (mind map) thank you
Rawan its linked in the discretion box
Thank you very much for your clear explanation. I used some of your video to prepare for the NCLEX RN exam and I enjoyed watching it. And....I passed!
congratsssssss!!!!!!
THANK YOU SO MUCH! I was struggling to understand how osmotic diuretics worked and i couldn't find the mechanism anywhere until now! Very helpful!
ruclips.net/video/YubDzhN5IRE/видео.html
Your drawings are awesome! You are so talented!
I can't express how great and detailed this video is
ur a legend for my exam tomrow ur ideal
I'm so impressed with how smart people have to be to know this stuff well. I see why people that know this stuff get paid. It's inspiring!
I am also a pharmacology teacher but still love the way u teach.....just love each and every video of urs
FASCINATING... I was merely trying to better understand what diuretics like coffee were & how they worked, but I got a whole lesson!! Loved it!!
I love your video I pass my exam because of you thank you
Actually after watching all these videos i don't really understand why do you guys hitting unlike button ................. even if u don't like these videos ,,,, why can't i just leave ????? please don't do this and learn to encourage them ..................
6 years after , still the best videos that explain diuretics
Your video is better than all over online class.
I watched your video when i was in last year of med school and it still helps me a lot❤
seriously your way of teaching is too good... i really liked your video.
This was so helpful! Love that you posted a link to the full photo. Just printed it off to help study. Thank you!!
I'm a visual learner... Your videos help big time! Thank you so much...
Thanks for your illustrated video. FYI you misspoke at 11:05 - thiazides increase absorption of urate not urea. Hence gout as a side effect.
No it is urea itself
Urea combines with sodium to form sodium urate which precipitates to form tophi or gout
Hey, I don't know whether this has been pointed out before, but urea has nothing to do with uric acid (urea cannot convert into urate/uric acid). Therefore, the information regarding the thiazide diuretics isn't strictly true, as thiazides promote the reabsorption of urate (not urea) at the distal convoluted tubule and so you end up with hyperuricaemia which can then lead to gout. I just wanted to point this out as it can lead to confusion. Otherwise an excellent video for learning the different classes and MOAs of diuretic drugs.
Really I like such oversimplified lectures which are making my life end proffession very simple and enjoyable.
That "WHAT!" at 14:43 sounded like either
1) Armando just made a mistake and is extremely pissed with himself
2) Armando is amazed at the abilities of spironolactone
thanx bro ur video took me to top 🔝 in my college
Thank you so much!
The best point in your explanation that you never get sick of repeating what is normally happening and THEN telling us what happens diffrently, it keeps reminding us and allowing us to compare the difference between the abnormal(in case of diseases) Or the pharmacological effect
If our doctors would bother to spare a couple of minutes to reminds of the normal during their explanation rather than "trusting" that the other (physiology/anatomy/histology) has done it before them, i won't be half as lost as i usually am, and my circulating problem is that when i get lost i lose interest and i tend to zone out the rest of the lecture....
Thus I am extremely thankful for your videos, Thank you!
these compounds are used commonly in my sport, and I now have an incredible understanding of their actions------thank you so much for sharing what must have been years of study
I'm a visual learner and your videos definitely help me. Thank you!
Thanks for this video. It's amazing. Also, whoever is drawing is a really good artist. Not sure if that's you or not.
Accidentally slept through a test. So starts my waiting period binge-watching this while waiting for the next scheduled one!
my life would have been easier if those videos came out before i finished my studies -.-
but thanks man we can still learn :) keep it up!
Thanks for all of the hard work you are doing, it is greatly appreciated by everyone. I believe you should make this artwork into a PDF document and post it on a website for students to download. While the video is great, the notes would help us study for exams, etc. without having to be at a computer. Thanks again.
Thank you so much for this amazing video! It helped me to understand everything about diuretics now. Greetings from Germany 🇩🇪
I love your handwriting!
Thanks so much. I'm taking Pharm right now and your video makes so much sense. Why can't you be my professor? ☺️
Really good video to explain how Diuretics work, thanks a lot ...
Thank you for this video, word for word from my veterinary pharmocology class but perfect for a visual learner like me!
Excellent explanation and illustration sir.....thank so much for making these videos🥺
Clearly described, spoken, highly recommend this lesson, thank you
Very simple and concept clearing....hatts off sir
Man seriously u r a great teacher
Thank u for such easy explanation
Excellent video! Did you mean symporter rather than symptomer?
Thank you sooo much!!! I love you for dedicating your time to make Pharmacology fun and easy. ❤❤❤❤❤
CLASS OF GENIUSES.... I AM AMONG
for Thiazide,
I think it is not so much that the Thiazides inhibits the excretion of Calcium, but rather, while inhibiting the NaCl cotransport, it reduces the intracellular Sodium concentration, promoting the NaCa2 transporter (on the blood side) to give to the cell sodium in exchange for Ca2. Therefore, calcium in the lumen will enter the cell and exit via the NaCa2 transporter into the blood.
also,
Aldosterone does not only promote the synthesis of NaK-ATPase, it also increases the production of regular old Na+ channel~
14 and cramming for the Science Olympiad, very helpful thanks!!!
in thiazide diuretics na/ca exchange increase, and gives you hypercalcemia not hypo.
Raissa Canales he didn't mention that in thiazide it will cause hypocalcemia he only mentioned that calcium will be not be reabsorbed in which it won't be excreted in the urine causing increase in ca in plasma. replay the video.
you are so Creative ... keep learning us .
The best diuretic video ever! Excellent
Hands down men. You are absolutely awesome.
sir i'm a pharm d student and you are like my cology teacher because i almost studied every topic from here..plz sir at the end show the whole page so that we can take screen shot as it will help ous to revise quickly ..can you plz share the pic of the whole sheet plz plz plz
This is incredibly helpful. Thank you so much for posting this video.
Your explanation is amazing😍
Armando, great work. Thanks.
I would love to have this artwork in PDF form. Would be a terrific study/reference guide.
Stephen Stevens there is a link in the description box
I also learned that ADH and Aldosterone both work on principal cells. But I do know that Aldosterone DOES stimulate the H+ ATPASE on alpha intercalated cells. (alpha = secrete H+, beta = secrete HCO3-)
I was surprised I didn't see the K+/H+ antiport and the H+ ATPase in the alpha-intercalated cells. Considering that renal distal tubular acidosis causes hypokalemia as well. Using diuretics with that would just worsen it considering loop and thiazide diuretics are K+ wasting.
Nice and beautiful way of explanation.
Good videos for beginners .. great effort
you are very good at teaching.
Best video of Diuretics
You are amazing!!!!!THANK YOU SO MUCH for offering me this! I love what you're doing
WOW! You hope me to understand pharm and now it's simple :) Great job!
The video was very easy to follow. Thanks.
Hi I really like your simple and precise way of explaining concepts! Please continue making such beautiful and helpful videos. P.S."Symptomer" @ 2:42 should be corrected to "symporter"
kept on making me think of maths.
a true legend, thank you.
This video is really amazing ^__^
Thank you so much for helping me understand the way diuretics work 👍
There is one teeny tiny thing though : You talk waaay too fast and sometimes I find it hard to keep up while taking notes , so can you please slow it down a little bit 😊
Thank you so much, i'm really grateful...
hey ur doing a really good job... please keep posting videos like this.. helped me for my finals... thank u so much...;-)
A great video!, but just one thing, at 14:10 you are stating that spironolactone (aldosterone inhibitors) are working on intercalated cells, but in fact spironolactone (aldosterone inhibitors) - their target cells are Principle cells, as well as aldosterone - his main target cells are as well Principle cells, but again, a great video thank you!
awesome... thank you so much sir.
Thankyou so much🥺❤️
I would recommend students studying medicine to see your videos as it is well organized.
Very nice and fruitful lecture.
excellent tutorial, better than my lecturer
Thank you somuch for the video. Hope you stay happy and healthy and richhhh
This is Awesome! Thank you Armando, you are now my new study buddy :)
FINALLY someone I can understand. Thank you so much! #nursingstudent #visuallearner
One correction - thiazide diuretics promotes the reabsorbtion of calcium and not magnesium....
Thanks sir, U really help in my exam
Thank you, Armando. What an amazing video.
Great drawing and explanation...
thank you, very clear and interesting. i am sure this will be useful for my exam next week :)
Great video, Armando!
love to watch your video.
very clear explaination with the help of awesome drawing/diagram.
thank you sir
Very detailed and informative! Thank you!!
Very nice explanation and art work
Thank you so much. Your explanation are so grate and useful👌👌👌
very clear n simple explanation... thanks
Thank you so much .
You made me understand all of diuretics so easily and made the subject interesting as well .