As for Metoclopramide, it is also said to block 5HT3 receptors to some degree (antagonist). Interestingly, the mentioned increased gastrointestinal motility is initiated through the stimulation of 5HT4 receptors (agonist), which lead to a release of acetylcholine. Very good video, thank you!
The cause of motion sickness is not limited solely to the inner ear. It's because the different organs which we use to determine our position in space (inner ear, eye and cerebellum) sometimes send incompatible information to higher centers, resulting in nausea. That's why sitting in the front of the vehicle helps with motion sickness - because then we see the road moving in front of us, which is more in line what our vestibule and cerebellum pick up on.
*Chlorpromazine 😊 Thank you for making concepts easier, making me understand things I couldn't quite understand from my books ❤️ right when finals are around the corner 😂
Obey Jesus Christ or you will go to hell, turn to the Lord before its too late, if you don’t REPENT OF YOUR SINS then you will likewise perish in hell. All liars, fornicators, adulterers, idolaters, blasphemers, whoremongers, thieves, murderers, homosexuals, effeminate, etc, will not inherit the kingdom of God. Once you turn to the Lord, read the new testament in the bible, the gospels, to develop a relationship with God. God bless you all. Turn to Jesus, repent or perish, turn or burn.
You probably should've mentioned this small detail regarding the medulla oblangata since it's pretty high yield: not only does it contain the vomiting center, it is also the reason why alligators are ornery (despite what mama says).
Would love a updated video that includes Neurokinin-1 Receptor antagonists (Substance P antagonists) like aprepitant, fosaprepitant, netupitant, etc. Great video!
Hi Armando; amazing video thank you. I am an advanced practice paramedic in the UK currently doing a prescribing course and this was really helpful. Maybe a little more info on the pharmacokinetics e.g. absorption, elimination and half life etc would have been extra amazing too...although I get that this is not where you were pitching this. Thanks and keep them coming.
Fascinating. Our own bodies produce an effective anti-emetic, from one of those glands in the neck area. You can test it out by taking little sips of something that really "doesn't agree with you". When your body tells you either to stop or to throw up, ignore it and carry on. You'll feel something flow into the back of your throat which will quell your need to vomit. It has quite a distinctive taste, which I can't really describe, but pleasant. I understand it's a very functional thing for other species, though it rarely comes into play for us. Have a bucket handy if you try this experiment.
I've experienced hyperemesis with all my pregnancies, currently my 3rd pregnancy and this was surprisingly the 1st time antiemetic medication helped at all.
in the vomiting center, there are other several receptors like serotonin receptor cause if the vagus nerve transiting the serotonin signals it makes sense that it is only can attach to serotonin receptors but overall this was an amazing video thanks so much for your hard work
coming from an emetophobe, I can say with confidence that vomiting is, in fact, voluntary. I've been motion sick millions of times, have had food poisoning and norovirus amongst other forms of gastritis... as well as a concussion..and haven't puked since 2005 ;) xo
Savannah Whitacre I am the exact same as you Savannah. I have been emetophobic my whole life and I haven’t vomitted in years. I have used medications like ondansetron to stop vomitting. I have felt nauseous but never vomitted.
Thanks Armando for a great video! One question; in the part about the vomiting reflex you say that one of the symptoms of the reflex is a tachycardia. Should't that be a bradycardia because of the vagal response when the vomitingcenter is triggered? Thanks again! Greetings, Jaap (the Netherlands)
Thank you so much for this video. We were just taught this topic in class, I forgot to bring along my book to review, so I was super happy to see this uploaded, helped alot.
Thank you sir ......🙏🙏 What are about CB1 receptor agonists such as nabilone & dronabinol which can be used to treat nausea & vomiting by stimulate CB1 receptors centerally in CTZ & peripherally in GIT ??
video is really nice. but please give the mechanism of action of prokinetic drugs like metoclopramide , dompirodone. u gave details about CNS effect hw it acts on g.i. please elaborate.
Excellent lecture! Never saw anyone make barfing look so fascinating and artistic! I'm serious. If you can do that for this topic, you can do it for anything,. Fantastic job 🙂.
you are a guru mehn...i can kiss u a billion times...u just made my day! make more videos on any health conditions and pharmacological approach...thanks a lot!
Thank you for the video as it was very helpful to understand. You mentioned that Ondansetron is not recommended for 1st trimester, why? What could be the side effect to the fetus?
question: so If vagus nerve carries the message from stomach using 5ht, the vomiting centre does not have 5ht receptors, the ctz has the receptor for 5ht. you did not say if vomiting centre communicates with ctz, you said ctz relays info to vomiting centre? please explain? how does 5ht will cause vomiting reflux if vomiting centre has musicraic receptors?
Can I ask you where dexamethason, canabinoids, benzodiazepines and NK1 receptor antagonists act? My professor told us they are anti emethics too but he didn’t say where their action was...Anyways thanks a lot, the video is clarifying!
Hi Do you have a full photo/poster of you drawing please i can copy as i find pictures so much easier to understand but cant screenshot a full pucture. Thanks
Does anyone know what would be the best type of antiemetic medication to take to deal with the side effects of antibiotics to treat an H. Pylori infection?
🧠 TEST YOUR KNOWLEDGE FROM THIS LECTURE! ✅
youmakr.ai/test-playground/questionnaire/673d3d72859b9c170836ed53
As for Metoclopramide, it is also said to block 5HT3 receptors to some degree (antagonist). Interestingly, the mentioned increased gastrointestinal motility is initiated through the stimulation of 5HT4 receptors (agonist), which lead to a release of acetylcholine.
Very good video, thank you!
The cause of motion sickness is not limited solely to the inner ear. It's because the different organs which we use to determine our position in space (inner ear, eye and cerebellum) sometimes send incompatible information to higher centers, resulting in nausea. That's why sitting in the front of the vehicle helps with motion sickness - because then we see the road moving in front of us, which is more in line what our vestibule and cerebellum pick up on.
Make more videos on pharmacology please...it will be helpful.
😂
Which year now sir or what you are doing now
I
Mo
We need an antibiotics video next! 😁
Already done my friend.
ruclips.net/video/IVBCrzjOl40/видео.html
Afiq Syahmi uiii
Thanks!
I am 27 and a stroke survivor I find your videos extremely helpful. I have ataxia. I find that when I
bro got stroke in the middle
@@naveedmemon4055oh my word and we still haven't heard from them! 😢
i love to learn !! best feeling in the world, and it's free!!!!
Yes!!!
ahhh pathopysiology plus pharmacology
best video ever made
You are such a life saving angle. Keep up the good work sir
*Chlorpromazine 😊 Thank you for making concepts easier, making me understand things I couldn't quite understand from my books ❤️ right when finals are around the corner 😂
Obey Jesus Christ or you will go to hell, turn to the Lord before its too late, if you don’t REPENT OF YOUR SINS then you will likewise perish in hell. All liars, fornicators, adulterers, idolaters, blasphemers, whoremongers, thieves, murderers, homosexuals, effeminate, etc, will not inherit the kingdom of God. Once you turn to the Lord, read the new testament in the bible, the gospels, to develop a relationship with God. God bless you all. Turn to Jesus, repent or perish, turn or burn.
You probably should've mentioned this small detail regarding the medulla oblangata since it's pretty high yield: not only does it contain the vomiting center, it is also the reason why alligators are ornery (despite what mama says).
never understood antiemetics and vomiting so well before! thanks
amazing illustration and explanation. keep up the great work!
Would love a updated video that includes Neurokinin-1 Receptor antagonists (Substance P antagonists) like aprepitant, fosaprepitant, netupitant, etc. Great video!
Hi Armando; amazing video thank you. I am an advanced practice paramedic in the UK currently doing a prescribing course and this was really helpful. Maybe a little more info on the pharmacokinetics e.g. absorption, elimination and half life etc would have been extra amazing too...although I get that this is not where you were pitching this. Thanks and keep them coming.
Fascinating. Our own bodies produce an effective anti-emetic, from one of those glands in the neck area. You can test it out by taking little sips of something that really "doesn't agree with you". When your body tells you either to stop or to throw up, ignore it and carry on. You'll feel something flow into the back of your throat which will quell your need to vomit. It has quite a distinctive taste, which I can't really describe, but pleasant. I understand it's a very functional thing for other species, though it rarely comes into play for us.
Have a bucket handy if you try this experiment.
I will have my Oral revalida next week and this video makes it easier for me to remember all about antiemetics.
I've experienced hyperemesis with all my pregnancies, currently my 3rd pregnancy and this was surprisingly the 1st time antiemetic medication helped at all.
Sir ,you are a very good teacher.
Where can i find this paper complete as it's a good summary?
❤️
جزاك الله خيراً 🤲
Thank you so much you make med school survival seem so easy 😍
in the vomiting center, there are other several receptors like serotonin receptor cause if the vagus nerve transiting the serotonin signals it makes sense that it is only can attach to serotonin receptors but overall this was an amazing video thanks so much for your hard work
Great video 👍very helpful
coming from an emetophobe, I can say with confidence that vomiting is, in fact, voluntary. I've been motion sick millions of times, have had food poisoning and norovirus amongst other forms of gastritis... as well as a concussion..and haven't puked since 2005 ;) xo
Savannah Whitacre I am the exact same as you Savannah. I have been emetophobic my whole life and I haven’t vomitted in years. I have used medications like ondansetron to stop vomitting. I have felt nauseous but never vomitted.
@@kimberleywilliams5199 is ondansetrone better than metoclopramide
Great video. This was perfectly designed and executed.
What are the best and safest anti emetics for vomiting from antibiotics
Absolutely love the explanation of N/V. Straight to the point.Thank you.
Thank u very much for ur help sir. This is very important .
Thanks again. ❤
From Srilanka 🇱🇰
You’re amazing sir , love your diagrammatic explanation ❤️❤️
You are king 👑 of pharmacology
Thanks Armando for a great video! One question; in the part about the vomiting reflex you say that one of the symptoms of the reflex is a tachycardia. Should't that be a bradycardia because of the vagal response when the vomitingcenter is triggered? Thanks again! Greetings, Jaap (the Netherlands)
Amazingly explained!! You are doing a superb job👏🏻👏🏻
Thank you sir ...🙏🙏🙏
Amazing video .. ❤❤❤
Marvellous effort Sir !! Keep it up ... My many concepts are clear now ..
Make more videos on pharmacolgy please you are professional ❤
Thank you....when i saw my textbook, it was looking so confusing, now it has become easier..💜
This was nice and was pretty much just like what's in my notes, so thank you!
Thank you so much for this video. We were just taught this topic in class, I forgot to bring along my book to review, so I was super happy to see this uploaded, helped alot.
Thank you sir ......🙏🙏
What are about CB1 receptor agonists such as nabilone & dronabinol which can be used to treat nausea & vomiting by stimulate CB1 receptors centerally in CTZ & peripherally in GIT ??
thank you for this great video. It is covered a lot in the short time
video is really nice. but please give the mechanism of action of prokinetic drugs like metoclopramide , dompirodone. u gave details about CNS effect hw it acts on g.i. please elaborate.
Take it, take the vomiting centre out of me, please! Haha
Excellent lecture! Never saw anyone make barfing look so fascinating and artistic! I'm serious. If you can do that for this topic, you can do it for anything,. Fantastic job 🙂.
Pronunciation may differ..BT explanation was grt sir..thank uh sir🙏
better explain and classify antiemetics drugs here than lippincot
you nailed it
Amazingly explained 💯
you are a guru mehn...i can kiss u a billion times...u just made my day! make more videos on any health conditions and pharmacological approach...thanks a lot!
You are amaaaaaaaaaaaaaazing !!! Thanks from the bottom of my heart, you really helped me a lot with this useful video
Thank you for the video as it was very helpful to understand.
You mentioned that Ondansetron is not recommended for 1st trimester, why? What could be the side effect to the fetus?
It is so helpful....and make concept much clear...thank you sir
that was amazing, keep doing what u do ♥ thank you
Awesome explanation. Thank you
Bro.. am a huge fan for you.. please explain pharmacology of antileprotic drugs
You have lovely ability! Thank you so much
Thank you 🙏🏻 ❤
Man u r Just genius...
That's only i can i say u...
thank you for this, I know understand the physiology of emesis and the basic pharmacology of anti-emetic drugs. 😊⭐
Thank youuu very much
Can you add the summery part at end of the video ?
Ur videos are very clear tnx 🤩
Great explained....great job sir
U r the best. U cleared all my doubts
Very helpful thanks ❤
i read it as antimemetics and didint expect this.
thanks for this short lecture 😎🙌
The best video for nursing students. just wondering the physiology of self induced vomiting
Beautiful information ma man, good job. Keep up the good work.
question: so If vagus nerve carries the message from stomach using 5ht, the vomiting centre does not have 5ht receptors, the ctz has the receptor for 5ht. you did not say if vomiting centre communicates with ctz, you said ctz relays info to vomiting centre? please explain? how does 5ht will cause vomiting reflux if vomiting centre has musicraic receptors?
Thank you very much
amazing teaching way
I think the vestibular apparatus doesn't go through the CTZ but via the cerebellum and activates the Vomiting Center
Thank alot sir for all the videos you made cology so easy and Interesting... 😇
So good, you should give more examples drug, thankyou
Heyy could we get the image uploaded for this video pleassee? :)
that would be SOOOOO nice :-)
Pls. Do
Thank you so much for making this wonderful video ...it is really helpful 🌺
keep posting, your videos are blessings for us:)
hi gus i dont find the complete image of this to download!can anyone help me??
take screenshots while watching 😂
Did You find one...?
Great! U should put the whole pic at the end so we can capture it pllzzzzzz
Please do make a video on laxatives....Love your videos...very helpful...thank you
wassup man! longtime no see!
Amazing experience sir but we need more videos
Can I ask you where dexamethason, canabinoids, benzodiazepines and NK1 receptor antagonists act? My professor told us they are anti emethics too but he didn’t say where their action was...Anyways thanks a lot, the video is clarifying!
Hi
Do you have a full photo/poster of you drawing please i can copy as i find pictures so much easier to understand but cant screenshot a full pucture. Thanks
Great ....🎉🎉🎉🎉
What is about nausea & vomiting caused by opioids use such as morphine .. ?? How can it be prevented ???
This video helped me so much ! Thanks alot :D Please can you make a video about Anti-anaemia and Haematinics!
Thats ultra perfect thank u so much 😭😭
I think, it is a hyoscine instead of ayoscine. Great video anyway. Thanks :)
amuhaimin _ He says this in the video but wrote the class down.
great job.... thanks for this vedio...☺
Its soo good 😇thank you
What aweasome explantion 😍
sir what about mechanisam of action pf neurokinin 1 receptor antagonist ex aprepitant drug
Thankyoou so much Armando , you are the best teacher (Y)
It is a great video. really made it easy and simple to understand and perfectly designed.
Great video sir.. Thanks..
Sir can u share some knowledge about CVA topic if possible plz!!
Thanks alott sir
Does anyone know what would be the best type of antiemetic medication to take to deal with the side effects of antibiotics to treat an H. Pylori infection?
My inquisitive approach nto knowledge send me over here...very informative
amazing video, thank you
BRING BACK THE BRACELETS
Great job thanks so much