How to analyze experimental data before fitting mechanisms
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- Опубликовано: 7 сен 2024
- This is talk 10 from the UCL summer school: Analysis and interpretation of single ion channel records and macroscopic currents using matrix methods.
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The main reference is:
Colquhoun, D., & Sigworth, F. J. (1995). Fitting and statistical analysis of single-channel records. In B. Sakmann & E. Neher (Eds.), Single Channel Recording (pp. 483-587). New York: Plenum Press. Available at www.onemol.org....
Analysis of simulated experiments to test the HJCfit fitting method
Colquhoun, D., Hatton, C. J., & Hawkes, A. G. (2003). The quality of maximum likelihood estimates of ion channel rate constants. J Physiol. (Lond. ), 547(Pt 3), 699-728. Retrieved from www.ncbi.nlm.ni.... Available at www.onemol.org....