Fitting mechanisms to observations (glycine and nicotinic ion channels)

This is talk 11 from the UCL summer school: Analysis and interpretation of single ion channel records and macroscopic currents using matrix methods.
Click 'SHOW MORE' for links to references.
If no link is given, copies of the full text can be downloaded at www.onemol.org.... (experimental papers) or from www.onemol.org.... (theory papers).
Burzomato, V., Beato, M., Groot-Kormelink, P. J., Colquhoun, D., & Sivilotti, L. G. (2004). Single-Channel Behavior of Heteromeric {alpha}1{beta} Glycine Receptors: An Attempt to Detect a Conformational Change before the Channel Opens. Journal of Neuroscience, 24(48), 10924-10940. Retrieved from www.jneurosci.o.... Available at www.onemol.org....
Analysis of simulated experiments to test the HJCfit fitting method
Colquhoun, D., Hatton, C. J., & Hawkes, A. G. (2003). The quality of maximum likelihood estimates of ion channel rate constants. J Physiol. (Lond. ), 547(Pt 3), 699-728. Retrieved from www.ncbi.nlm.ni.... Available at www.onemol.org....
Remigijus Lape, David Colquhoun & Lucia Sivilotti (2008) On the nature of partial agonism in the nicotinic receptor superfamily (2008).Nature. 454, 722 - 728. Available at: www.onemol.org....
Schorge, S., Elenes, S. & Colquhoun, D. (2005). Maximum likelihood fitting of single channel NMDA activity with a mechanism composed of independent dimers of subunits Journal of Physiology 569, 395 - 418. Available at: www.onemol.org....