Fitting mechanisms to observations (glycine and nicotinic ion channels)
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- Опубликовано: 7 сен 2024
- This is talk 11 from the UCL summer school: Analysis and interpretation of single ion channel records and macroscopic currents using matrix methods.
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If no link is given, copies of the full text can be downloaded at www.onemol.org.... (experimental papers) or from www.onemol.org.... (theory papers).
Burzomato, V., Beato, M., Groot-Kormelink, P. J., Colquhoun, D., & Sivilotti, L. G. (2004). Single-Channel Behavior of Heteromeric {alpha}1{beta} Glycine Receptors: An Attempt to Detect a Conformational Change before the Channel Opens. Journal of Neuroscience, 24(48), 10924-10940. Retrieved from www.jneurosci.o.... Available at www.onemol.org....
Analysis of simulated experiments to test the HJCfit fitting method
Colquhoun, D., Hatton, C. J., & Hawkes, A. G. (2003). The quality of maximum likelihood estimates of ion channel rate constants. J Physiol. (Lond. ), 547(Pt 3), 699-728. Retrieved from www.ncbi.nlm.ni.... Available at www.onemol.org....
Remigijus Lape, David Colquhoun & Lucia Sivilotti (2008) On the nature of partial agonism in the nicotinic receptor superfamily (2008).Nature. 454, 722 - 728. Available at: www.onemol.org....
Schorge, S., Elenes, S. & Colquhoun, D. (2005). Maximum likelihood fitting of single channel NMDA activity with a mechanism composed of independent dimers of subunits Journal of Physiology 569, 395 - 418. Available at: www.onemol.org.... Наука