👉 LINKS 👈 Disclaimer: This video and description contain affiliate links, which means we may receive a commission if you click on one of the product links. I appreciate your support of this channel! Alpha Lipoic Acid (Antioxidant beneficial in Neuropathic pain, Diabetes. Watch this for more: ruclips.net/video/9SROQJl-a6I/видео.html R-Alpha Lipoic Acid: geni.us/RAlphaLipoicAcid Alpha Lipoic Acid & Vitamin C:geni.us/AlphaLipoicVitaminC Budget Alpha Lipoic Acid: geni.us/BudgetAlphaLipoic Omega 3 Fatty Acid (Check how much EPA & EHA in it, not the total fat content): Watch this for more: ruclips.net/video/8CVHgrf-FLQ/видео.html High % EPA & DHA Omega 3 Fatty Acid: geni.us/Omega3-2000mg Best Vegan Omega 3: geni.us/VeganOmega-3 Best Omega 3 1,000: geni.us/Omega3Nutricost1000 Best Omega 3 2,500: geni.us/Omega3Nutricost2500 Best Krill Oil: geni.us/BestKrillOil Best Neuropathy Multivitamins: Best Cream: geni.us/jSCBc Multivitamin for Men: geni.us/MultivitaminMen Multivitamin for Women: geni.us/MultiVitaminWomen Organic Beet Root: geni.us/OrganicBeetRoot Acetyl-L-Carnitine: geni.us/Acetyl-L-CarnitineXL Acetyl-L-Carnitine Powder: geni.us/AcetylLCarnitinePowder Arginine AKG: geni.us/ArginineAKG Best Magnesium Supplements: Magnesium Video: ruclips.net/video/5DzSw8Ynhpo/видео.html Best Magnesium L-Threonate: geni.us/Magtein Best Magnesium Citrate: geni.us/MagCitrate Magnesium Citrate Powder: geni.us/MagCitratePowder Best Magnesium Glycinate: geni.us/MagGlycinate Magnesium Glycinate Powder: geni.us/MagPowder Vitamin D3 & Vitamin K2 Supplements: Watch this Video: ruclips.net/video/esTz-_Mpm4Q/видео.html Liquid D3 + K2: geni.us/LiquidVitD3K2 Best Vitamin D3: geni.us/VitaminD3-10k Best Vitamin D3 + K2: geni.us/VitaminK2D3 Best Vitamin D3 5000: geni.us/VitaminD3-5000 Vitamin K2 MK7: geni.us/VitaminK2 Turmeric (Anti-inflammatory benefit spice): Watch this for more: ruclips.net/video/hIoGWnAv2YM/видео.html Best Turmeric Curcumin: geni.us/TurmericNutricost Benfotiamine (Vitamin B1 Thiamine): Video: ruclips.net/video/BFjwxefiBUY/видео.html Best B-Vitamin Complex: geni.us/VitaminBComplexBest Vitamin B12: Video: ruclips.net/video/s9xDeZyLb50/видео.html Best B-Vitamin Complex: geni.us/VitaminBComplexBest Vitamin B12: geni.us/BestVitaminB12 Glucosamin Chondroitin MSM: geni.us/ChondroitinGlucosamine
Thank you! I have just come across your channel and had found the above vlog extremely insightful. I live in South Africa and CDS has become a buzz word. Do you have any knowledge on this and if you do, what is your take on it?
Thanks for sharing this video it confirms wihat I know of alpha lopoic and promoting eating of veggies good presentation up to promoting eating any animals it’s always disappointing when promoting health they throw in eating meat or fish…
I went on Keto diet and OMAD intermittent fasting. All my neuropathy pain went a way, prior to that I took r-lipoic acid as the same brand you recommended. I took 600-1200, it didn’t work as well as changing my diets. X-out all the processing food, refined carbs and sugars and omega- 6 oils. Straight Whole Foods and intermittent fasting! It also removed my osteoarthritis. It took effective within 21 days. I will continue with this diets and fasting the rest of my life. I love it. Let’s food be Thy medicine!
I am using HMS Nutrition LLC for R-Lipoic Acid. As for Keto diet, I am not a vegan Keto. I eat animal products , vegetables, nuts and seeds and combine with intermittent fasting. I eat twice per day with 18:6 Intermittent fasting for 5 days, then I eat one meal per day (OMAD IF) for the last two days of the week. I am on this Keto diet and IF, my body needs a lot of vitamin B complex and electrolytes. I drink two tsps of moringa powder daily to remove any oxidized LDL and provides 92 essential nutrients. I also take raw vitamin B complex, B12 has to be form methylcobalamine, not cyanocabanomin ( manmade). I drink 1 scoop of electrolytes powder per day. The 4 main electrolytes are potassium, sodium, magnesium and calcium. Everyone needs 4,700mg per day and sodium is half of that to get the cells to be hydrated and functions properly. It’s hard to get potassium. Eat bananas, it has a lot of starch and sugars, it’s not a keto friendly. Avocado has 76% fat, 16% carbs and 5% proteins. I eat two avocados per day. I also eat 1-2 tablespoons of northern white beans, it has the richest source of potassium, but it’s high in carbs. My advice is anyone decides to get on any special diets, needs to do a lot of research and understand the body needs. I recommended to watch the videos from Dr. Sten Ekberg, Dr. Eric Berg and Rayan Taylor. These ppl are very knowledgeable about nutritions, diseases and cancers. If you do the intermittent fasting, it’s a must in any diets you choose. Keto diet, you trained your body to use fat for fuels. Sugars damaged the liver, glucose damaged the brain cells. Use MCT oil while you are fasting, it feeds your brain, you feel the fullness and no cravings. Eat all your calories in one hour, then your next meal is at least 6-8 hrs window for beginners. Also, take 1-3 tsps of organic raw unfiltered apple cider vinegar in a cup of water 20-30 min before each meal. I enjoyed eating like this very much. My body prefers fat over sugars and carbs. I have a lot of energies, clarity, focus, well sleep and happy.
I did the same thing. Then went to an idiotic neurologist who tested me for neuropathy, and she said, "you don't have a neuropathy. Your nerves are healthy. But we'll do an mri just to make sure" I say idiotic because she was convinced neuropathic symptoms can't resolve with diet changes. The symptoms resolved when I changed my diet to mostly non-startchy vegetables and meat. I add in bits of yogurt and quinoa here and there, and a splash of berries and statchy veggies. Bits because these are quick to raise glucose levels and the primary key to fix neuropathy is eliminating surgar. Salt is low with this so I've got LMT electrolyte powder on the way, along with drinking chicken broth in the morning here and there. Keto will elevate your LDL, and make you risk gallstones, so I would recommend a slow switch to keto and not a drastic one. You fix one problem and it starts another. Prevent the gallstones by drinking 2.5 litters of water. I wouldn't do keto without research or with the guide of a doctor who can test your electrolytes cause you can mess yourself up pretty easily.
@@bleeblah3583 Yes to all of that... I would just add that from my research, I suspect ACTUAL KETO is very good for some specific problems and can be used as SHORT term treatment. But I have come to believe that most of the LONG TERM benefits attributed to Keto are actually derived from the "LOW-CARB" part of the diet and IF. Striving for CONSTANT DAILY KETOSIS may turn out to be a LESS optimal as a lifestyle.. All The Best, Stay Well : )
I was taking the cheap, s type crap, for several months -- zip, nada, nothing. I heard about the R type, got it the same day. Cost more!! But the very same night I took one pill of the magic stuff: a miracle. I could walk across the floor without enormous pain. Thanks so much for getting the word out. KISSES & HUGS!!!
That’s what I been researching. S&RS are synthetic or the S cancel out the R I agree it’s not cheap But considering what I have done to my body. It’s a bargain if you feel good.
Thank u since April I have had a lot of nerve pain and my feet are saying “don’t walk on me”. I so sad because I’ve always been athletic. I’m starting this vitamin now so I pray it work for me.
Please look into Viitamin B 1 ( Benfotiamine) MEGA DOSE for example 1200 plus 2x daily - it is not harmful‼️ PLEASE read reviews and you will be able to resume your active lifestyle✝️🧡
Congrats! You are the second doctor to mention the two types of ALA. I just found out what I've been taking probably has the type S in it. They are also mixing the two kinds to save money. Some call those a third type but it's really just the two. They should have to stop selling the type S. Type R is the natural kind.
I think the process for manufacturing synthetic ALA produces equal amounts of R (the naturally occurring one that works) and L (doesn't exist naturally, and won't work) which are not easy to separate, and that's why both together are cheaper.
@@red-baitingswine8816 Who cares if it's harder to make. The problem is the synthetic ones blocks the natural one from working. It should be illegal to use the synthetic kind.
@@stevenw4549Do you really think a company could sell a mixture of half R (active) and half S (inactive), if the S blocked the R? Feel free to pay more for the pure R isomer.. . The video gave no evidence that the S blocks the R - no studies, let alone controlled experiments. I suspect it's common knowledge among professionals that the R/S mixture works just fine.
@@red-baitingswine8816 They can and do. It is unethical. I used one for at least two years before I found out. There are other videos that specify the difference and that S blocks the R type. S does nothing so you pay for a worthless product. These companies only care about profits. They don't care if their product works or not, as long as you will buy them. Most people just think ALA is ALA and don't know about the differences. That is how those companies get away with it. I would rather pay a bit more for something that works as opposed to paying less for something that doesn't. If it doesn't work, then you might as well save your money and take nothing. The kind I buy now says on the label that it contains no type S and only contains type R. I've only been using it recently and can already tell an improvement in my neuropathy. Especially in my left hand which was the worst. Don't count on professionals knowing the differences. My doctor was the that suggested my trying ALA and he never mentioned the different types. They don't concern themselves with details about supplements. They concentrate on drugs. Through reading, I learned that because I take Metformin, I should be taking Ubiquinol which is active CoQ10 because Metformin depletes it. So I ask my doctor about it and he said yes I should be taking it. Yet he had not told me to take it before. I had to do my own research. So-called professionals know little about supplements.
The other doctor said there is a third kind. It is a mixture of the R and S type, which you may think is ok but still the same pro the S type cancels are benefit of the R Tyra.
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R-ALA has helped me hugely with bad neuropathic widespred pain. I have/had tingling, numbness, deep pain, deep internal and external itching, shocks, severe nerve pain, and water trickling sensations, sensitive "sunburn feeling" skin on my back,shooting pains, stinging pain everywhere. My right upper outer thigh bringing me the very worst agonizing pain the longest..it is now numb, as are other areas on my body. Way less heat sensations felt ( not sure about cold sensations), on my legs, chest, back. Horrible heavy legs feelings like there is cement inside them. Originally (not knowing) I had the good R-ALA which was helping, then when i went to purchase more, they werent carrying that one anymore, so I bought a different one, which turned out to be RS-ALA and i noticed my pains returning. By the time i had almost finished the bottle, i discovered a medical video much like this one, explaining the differences of Alpha Lipoic Acid, I checked my bottle and sure enough, i had bought the lousy kind the second time. I ended up ordering the R-ALA on-line and have been back on the good one a few weeks now, again HUGE IMPROVEMENT I am feeling...its working! Thank you!!! ❤
Oh thats why I feel nervous tension with this .. I was told vit depleted B1, a calming vitamin... And I am deficient in B1. I take Benfotiamine to calm my nerves
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Very good motivational inspiration!!! Here's the thing, through my own personal experience, I have come to find that taking the Ayurvedic approach of counter-balancing, I utilize 1000-2500 mg Bitter Melon before each meal, way cheaper than buying fresh veg. Further, I've found that if I eat like, pumpkin seeds in the evening for their magnesium, my feet burn, so I can either take the bitter melon before I eat, or take Chromium Picolinate to neutralize the pain. Berberine (600 mg.) is also great before eating. Experimenting with each of these gives one a lot of options that actually work to eliminate the pain ASAP!!!!
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My autistic brother suffered a stroke on Nov 2022, started taking R- Alpha Lipoic Acid, along with Magnesium and B12 vitamins, and he is know walking and talking more and more (10 weeks post stroke).
You can take this compound at much higher levels than what is recommended on the supplement label from jarrow or any other company. My opinion is that time release works better because it only sticks around in the blood about an hour and then a little more but not very long. You can read up on this. If you're not getting results, it is safe to take much more. I take one to 2,000 mg a day sometimes when I'm really pushing my boundaries with overtime work. You have to spread your doses out throughout the whole day when you take much larger amounts. I've done this for years. It keeps me from getting sick and keeps me looking young.
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We appreciate you watching and contributing! If possible, we would appreciate a quick rating (hopefully good), and it makes a HUGE difference for us! g.page/r/CaxJ9b-O6o27EAg/review We are working hard every day to make better and more meaningful content! This is what keeps us going for sure.
Make sure to get the stabilized form of R-lipoic acid. The Cyclodextrin kind is the best. I've been taking it for a month and it's helped relieve the nerve pain I had in my back as well as relieve the numbing tingling I had in my thigh.
I take alpha lipoic sustain with biotin for vegan Jarrow brand. I’ve been taking for about 4 years. Took for neuropathy but to my pleasant surprise I no longer have hypoglycemia symptoms which I had my whole life for me alpha lipoic is my miracle 🌈🌞
I’m excited for you and I’m hoping it helps me as much. Just bought this brand 2 weeks ago. Jarrow is the only brand I’ll buy because their products are legit. So fare I’ve noticed a huge energy boost. I feel more calm, not having anymore heart palpitations and the tingling I get in my legs and hands has almost disappeared. I am pre-diabetic. Can’t wait to get blood work done to see what my numbers are after taking these.
@@boomerang0101 it may be, but I’m seeing major improvements with my body already so I’m going to still with this. I’ll keep your suggestion in mind though. Thanks 😊
@@boomerang0101 Jarrow Formulas Alpha Lipoic Sustain with Biotin. It says you can take 1 300mg pill 1 to 2 times a day. I take two a day equaling 600 mg a day. I do one in the morning and evening. So far I’ve noticed huge burst in energy, no tingling through hands and feet, more calmness and I feel like it’s made my stomach feel way better. It’s still early so there may be more.
@@boomerang0101 oh also I am out of my add meds and can’t get a refill because the pharmacy is out of stock. This is helping md make it. Without my add meds my focus is off and I get very fatigued. It’s hard to get through the day. This gets me through the day easily and I do feel like I have been focused on it. Starting to wonder if I need my add meds anymore.
@@boomerang0101 one night I felt like it did, but I think because I took them to close together. I took the first one later morning. I was going to go down to one a day after that but something told me to keep taking two a day but try to take the first one as early as possibly.
You are a great fan, and we appreciate you Jenny! ruclips.net/video/qO9FsUph_Wk/видео.html These foods might be a good option as well! If possible, we would appreciate a quick review from you, and these make a HUGE difference for us! g.page/r/CaxJ9b-O6o27EAg/review Thanks again for watching!
We appreciate you watching! If possible, we would appreciate a quick rating (hopefully good), as it makes a HUGE difference! g.page/r/CSzlpzp7G82TEBM/review We are working hard every day to make better and more meaningful content! This is what keeps us going, for sure.
Thankyou, i am finding i have issues too after hip replacement surgery. I just brought the R ANA Capsules, 300mg - says to take one daily but after hearing you i will invease the dose
We appreciate you watching and contributing Maria, you are amazing! If there are any topics you want me to cover, just let me know! If possible, we would appreciate a quick rating (hopefully good), and it makes a HUGE difference for us! g.page/r/CSzlpzp7G82TEBM/review We are working hard every day to make better and more meaningful content! This is what keeps us going for sure.
Thank you! I have been taking the S Alpha Lipoic! No help and fooling myself because sometimes I had no pain but most night didn't sleep much because pain would wake and keep me up. I'll eat more greens and get the R-
Just knowing the chips will give me a horrible stomach ache from the grease cures my craving (bad oils w/ Omega 6 not 3, high temps break it down to toxic). Poor nutrition also causes cravings. Keto has helped me so much with all that.
@@gloriasaliba3395 Sorry to hear that! Amazingly...it MIGHT be lightly helping me. I've inconsistently used about 300-600 mg./day of stabilized R-ALA for 20 days or so and it SEEMS to help a touch with foot numbness. Are you using stabilized and pure R-ALA?
It is difficult to 100% lock this down in all honesty, but this is a proposed theory. At the very least even in that case you are getting 50% of what you are expecting to be getting. Let me know if you can find anything extra 😊
I contacted a supplement manufacturing company with this question about R vs. S alpha-lipoic acid, and they said all the studies that indicate it is effective in treating neuropathy have been done with a racemic combination of R and S. They stand behind that research. Hard to tell who to believe. My own oncologist said it didn't matter.
Lots of confusion in these comments, so let me try to clarify. The synthetic racemic mix of RS-ALA is not S canceling out R activity/bioavailability. Taking R-ALA is certainly active and bioavailable, but the RS-ALA mixture provides 50% of the active R-form and the S-form mixed in may in fact prevent the R-form from polymerizing (i.e., making it inactive). However, the relative effectiveness of pure R-form vs the RS-racemic mixture has not been quantified yet (but that doesn't mean the S-form is cancelling out the R-form activity). Here is the quote from the article (see also link below): "These results suggest that the R-enantiomer would be the most appropriate form to provide as oral supplements; however, S-LA in the racemic mixture may prevent the polymerization of R-LA and thereby enhance overall bioavailability. It has yet to be established whether R-LA, its salt form, or a racemic mixture would be best to use in future clinical studies." (see www.ncbi.nlm.nih.gov/pmc/articles/PMC2756298/)
the radical scavenging and chellating properties of ALA dont matter no matter if its the R or S form but the other effects such as the metabolic effects for blood sugar do matter. If you are taking it for diabetes then you need only the R form but if you are taking it for its radical scavenging properties then it doesnt matter.
I was having neuropathy. And have no reason. All test was normal non dibaetic. I tried every medicine nothing works. Finally i tried alpha loplic acid. 600mg was giving me vertigo. I go to 400 mg now months and my neuropathy is very much reduced. I feel like i was not having it
You must have brain MRI. Unfortunately if brain have lesions it leads to MS with such symptoms though all blood test and cervical X - Rays are ok.Same is with my case
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They are the best for diabetic neuropathy. It works for me and I have been able to carry a cup of coffee. Neuropathy come to me because of Metformin because it kills vitamin Bs. Some sellers sell ALA without expiration date and online sellers do not return them. Thanks Dr. For your excellent explanation
You are a great fan, and we appreciate you Ismael! ruclips.net/video/s9xDeZyLb50/видео.html Check our video on vitamin B12 as well! If possible, we would appreciate a quick review from you, and these make a HUGE difference for us! g.page/r/CSzlpzp7G82TEBM/review Thanks again for watching!
We appreciate you watching! If possible, we would appreciate a quick rating (hopefully good), as it makes a HUGE difference! g.page/r/CSzlpzp7G82TEBM/review We are working hard every day to make better and more meaningful content! This is what keeps us going, for sure.
THANK YOU for listing good quality sources! I need the good fish oil also. Have been wasting a lot of $ and time with tons of low quality vitamins from a well known online supplier.
Follow Up to my Post - I called the company and asked what my supplement was, she said 50/50...I guess I won't be buying that any more, as I'm 77 and want the full affect of the pill. #1- You're never too old to learn #2 - We learn something new every day #3- It's up to us to make the necessary switch to get & feel better....Wishing all here a Happy, Healthy New Year in spite of the bumps & challenges we will face...Are you spiritually ready ?
Most of the research showing ALA works has been done using the racemic 50% mixture that you have. I think the doctor is wrong about r-ALA being much better, although it is twice as strong per mg, that much is true. I would, at least, use the supplement you have until a new r-ALA supplement arrives at your door if you do decide to switch and pay the higher cost.
@@christophdollis1955 - Thank you for this information, this neuropathy came about from the sciatica attack I had in Jan...I would like to repair this numbness as quick as possible, it's an uncomfortable feeling from my knee on the outside down to my foot. I will continue and finish what I have, will try one bottle of the r-ala, and then switch back..I want to at least try it and see....not a comfortable un-feeling if you know what I mean...Happy New Year to you and yours...may it be a healthy 2023...
@@Twins0302 You're welcome. Incidentally, benfotiamine (a synthetic vitamin B1 supplement) is a prescription drug for sciatica in Germany. It, or sulbutiamine or TTFD, two other fat-soluble forms, legit may help. Benfotiamine most reliably gets to the peripheral nerves: sulbutiamine and TTFD get to them peripheral nerves, but they pass the blood-brain barrier moreso than benfotiamine (which offers certain benefits, especially for some people's depression, energy, etc.) and so probably a bit less of them get to the peripheral nerves. I like all of these forms, and mostly use sulbutiamine personally.
@@christophdollis1955 Hi Chris, a few Q's - how do you know about this B1, & isn't non synthetic better, I have been taking B Complex.? Q @2-what is your background....I am still taking Gabapenten 300 mg at lunch or dinner...once a day...just asking, I do research but you know quite a bit...
@@Twins0302 Synthetic is useless! Toss them.B vitamins have to be taken all together as in nature - they are created all together - so get a B complex or OD on nutritional yeast.
I thought R α-lipoic acid was unstable alone and needed to be combined with S α-lipoic acid to be functional as a supplement, so unless the product specifically states R α-lipoic acid, your getting a 50/50 blend according to a nootropic experts
I have NOW ALA and contacted them - since they put nothing on label. They said it was a combo of both - so you are saying that is the best way to take it vs taking R+ exclusively?
@@tracyau9122 No, I'm saying if you buy any ALA your likely getting both so you can buy the cheaper version ... I don't know who manufactures this stuff but there are mostly in a blend, it just the labeling that changes. I'll see if I can find the resource I used - ruclips.net/video/6sXT6Hnt3Bc/видео.html
Hello!! It’s my first time taking alpha lipoic acid and I realized that none r or a or s is written, just THIOTACID, on the label just ALA. In my country no other alternative. Is this the right one I am taking!! I am suffering from leg numbness, lack of toes’ mobility & unbearable pain under foot - just right leg. The neurosurgeon recommended this…… thank you
Thanks for the great response Lisa! Realistically its just a little less effective potentially, don't ignore your doctors advice if that is what is available! ruclips.net/video/tL-Vj0wODaw/видео.html This video may help as well! If possible, we would appreciate a quick and easy rating from you, and a good rating makes a BIG difference for us! g.page/r/CZWo3fJqJrVpEBM/review Thanks again for watching!
We appreciate you watching and contributing Angie! Let us know if we can cover any future topics for you. If possible, we would appreciate a quick rating (hopefully good), as it makes a HUGE difference! g.page/r/CSudMUZfg68sEAI/review We are working hard every day to make better and more meaningful content! This is what keeps us going, for sure.
Yes. Most of the research has been done on racemic 50% r-ALA 50% s-ALA such as the nutricost brand. You need twice as much of the racemic rs-ALA as you would r-ALA, but it's effective and economical and also more stable than r-ALA on its own. Instant release also seems to be MORE effect than continuous release. *"While the abstract of the Evans et al. paper mentions the change in Tmax (the time to maximal plasma concentration), it fails to disclose that the plasma concentration at that maximum (Cmax) was 45% lower in individuals taking the controlled-release lipoic acid compared to those taking the quick-release form. Additionally, the total absorption, based upon the area under the curve (AUC 0- 24 hours), was reduced by 42%." /// "While the abstract of the Evans et al. paper mentions the change in Tmax (the time to maximal plasma concentration), it fails to disclose that the plasma concentration at that maximum (Cmax) was 45% lower in individuals taking the controlled-release lipoic acid compared to those taking the quick-release form. Additionally, the total absorption, based upon the area under the curve (AUC 0- 24 hours), was reduced by 42%." /// "Furthermore, the modest oral dose of 300 mg/day of oral lipoic acid (racemic) in metabolic syndrome patients statistically improved endothelial function (measured by flow-mediated dilation), while decreasing the pro-inflammatory markers IL-6 and PAI-1 (plasminogen activator inhibitor-1). 10 Other positive clinical trials have also been reported using oral, racemic 'quick-release' lipoic acid for a variety of other health conditions in recent years.11,12,13,14 These data suggest that standard forms of lipoic acid do not suffer appreciable declines in clinical efficacy when used orally, compared to similar doses delivered intravenously and are currently the standard form in clinical experimentation and practice." /// "while there is abundant clinical research on the racemic form of lipoic acid, we are not aware of any published clinical trials, in humans, using R-lipoic acid; or any comparing R-lipoic acid with the RS-form. Second, since the R-form is derived by separating the two enantiamers, it is much more expensive than the racemic mixture. Without clinical data to suggest the effective equivalent dose, it seems premature to suggest the wide use of R-lipoic acid in clinical practice, and difficult to justify its use from a cost-effectiveness stand-point. Until future studies are performed and/or technological advances reduce the cost of R-lipoic acid, the use of racemic alpha-lipoic acid seems to be the most cost-effective choice at this time."( [excerpts from *"Technical Report-Time-Release Lipoic Acid: More Marketing than Data, July 2007"* from +POINTS INSTITUTE,+ Director: Thomas Guilliams, Ph.D."]
I make green smoothies with pineapple, ginger, lemon, spinach, water and a little pineapple juice. It is a good way to quickly get the greens. I don't have a fancy expensive blender, I use a food processor and then an emulsion mixer. I was skeptical but it actually tastes good.
Thanks for confirming what I have heard about R Alpha Lipoic. Can you tell me whether it is absorbed best with food or empty stomach? And is the NA sodium added good for it's absorption or shall I steer clear of the combo? Thanks again!
Thanks for the great response Sandra! Som reports state that there is a 40% better absorption on an empty stomach. It is also important not to cook the vegetables as it does ruin the alpha lipoic acid. I do believe most stable formulations are sodium as it is a negatively charged acid otherwise. Let me know how it works for you! If possible, we would appreciate a quick & easy rating from you, and a good rating makes a BIG difference for us! g.page/r/CaxJ9b-O6o27EAg/review Thanks again for watching!
@@scottharm3932 It's actually both water AND fat soluble, which is one of the things making ALA so excellent. That said, it's absorbed with or without food, but seems to be better absorbed on an empty stomach and you're right about that.
There are 3 forms of Alpha Lipoic Acid on the market: R-Alpha Lipoic Acid. S-Alpha Lipoic Acid RS-Alpha Lipoic Acid. The R-Alpha Lipoic Acid is the only pure form and costs a lot more than the synthetic ones, which are a waste of money! It is vital that YOU high-light this fact to your viewers!
Is the DL- Alpha Lipoic Acid the same as S-ALA? ( I tried DL to start because it was readily available) and all it did was cause an unpleasant urine smell, suggesting to me that it is not being absorbed at all, but just being flushed out as fast as it goes in. Then I switched to R-ALA (pricier) and developed a crazy itch all over my body even at only 200 mg/day. What gives??? I was taking it for neuropathic pain- not diabetic.
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I take Jarrow Formulas. Any supplements I take are by Jarrow because they test their products. Anything I’ve ever taken from them works. Btw I’m not in the market to sell this brand. I just love their products because they are high quality.
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Ian Vince Cruz, thanks for the great response! There are two schools in this topic. Some believe that due to lack of any empirical adverse effect ALC and K2 may be taken at the same time. However, due to theoretical interaction of ALC and K2 others recommend taking one in the morning while the other in the evening. Both methods are in use and there are practical and theoretical arguments supporting both way of taking ALC and K2. If possible, we would appreciate a quick and easy rating from you, and a good rating makes a BIG difference for us! g.page/r/CZWo3fJqJrVpEBM/review Thanks again for watching! All the best to you Ian!
yes! thank you thank you thank you! Needed that info on which typle of alpha-lipoic acid is synthetic! R-a lipoic acid is Natural yayy!! i'll let you know how is goes!
I read comments on Amazon. There are various ALA bottles not labeled as R, just ALA. People are reporting good results from these supplements. So just assuming they don't work may not be a good assumption.
I'm taking the NOW brand of Alpha Lipolic Acid. It's a capsule. I looked on the chart and it doesn't have the R or S before the name. It's labeled as..Alpha Lipolic acid (Granules)600mg. Am I wasting my money?
Thanks so much for this video, I started my a-lipoic acid treatment supplement, I already take spinach greens, b. sprouts,..etc. in my greens smoothy.... so my bottle doesn't say R- or S-...I'll call the company this week...
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I started with pain in the pancreas area, and after weeks, the pain spread practically to my entire back, mainly under the shoulder blades, the time came when it was unbearable and I couldn't sleep, I heard about R Alpha Lipoic Acid, and I investigated the correct dose for my neuropathy, I started taking 600 mg per day, and after a few weeks, the back pain practically disappeared, but I still had pain in the stomach area, so I increased the dose to 900 mg, and the pain on the right side The stomach area also disappeared, now, I'm just waiting to no longer have pain, and this happened in only two months, so it probably won't work for everyone, but in my case it has been a miracle, and I didn't have than spending money on doctors or hospitals, I have only spent a little more than $40.00 Dls, and I am extremely happy, so I do not agree with this Doctor's opinions, and like me, there are thousands of people with satisfactory results.
how long did you have neuropathy and back pain before you started taking alpha lipoic acid..did you take any other supplements... ruclips.net/video/Kzl0BOjLV38/видео.htmlsi=Y-cHQCAt1giSckDT
I’ve been taking the alpha lipoic acid for about 2 months now and it hasn’t done anything..so now i ordered the R-alpha I will give that a shot …I’m so miserable
not true i take regular alpha lopoic acid not the r one it helps me alot for 2 years for my depression much better then anti depressants helped me in the past and it helps alot for my nerve pain in my feet
I'd add something - everybody should check - R-ALA should be stabilized - than is multiple times more effective! If is not written on the package - probably isn't! Also - I'd like to ask you - is it same thing with pyridoxine - HCl and pyridoxine - 5 - phosphate. Are they compet too as the S- ALA and R- ALA ? Is it safe to take them both? I use 50 mg of P-5-P and 10-12 mg of P-HCL 'cause P-HCL is, almost,in every suplement... I enjoy to watch your videos - some of them many times - it's very helpful. Greetings from Serbia!❤
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Dr, really enjoyed yr great presentation. A chiropractor recommended 600 mg ALA 3 times a day. I feel thats quite much, do you agree, ? I'd appreciate yr opinion
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Alpha Lipoic acid has been tested on mice and apart from the benefits, tests showed that the lifespan of the mice who were give ALA was decreased by around a third.
You forgot to mention that some brands are labeled RS alpha lipoic acid just to confuse people into buying that brand. I love potato chips but they got too many carbs.
I bought R-ALA and then read it can take mercury from the amalgam fillings and possibly move through the blood brain barrier and get deposited into the brain. So I've been afraid to try it. As I am a type 2 diabetic. Anyone else heard of this?
Thank's for your videos love all the information from you learning things,so I checked my bottle I have and it does not tell me "r" or "s" so what's up with that?
Thanks for the great response! Usually this means its not pure R 😀 If possible, we would appreciate a quick and easy rating from you, and a good rating makes a BIG difference for us! g.page/r/CSudMUZfg68sEAI/review Thanks again for watching!
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If I'm not mistaken the S type doesn't act against the R type - it just doesn't do anything. The chemical process used to manufacture synthetic ALA produces equal amounts of R and S, which are not easy to separate. . Anyone who claims that the S type acts against the R type needs to cite a scientific study with those results. . Of course anyone is free to spend the extra money to get the pure R type.
My supplement doesn't have the R or S on it. How can I tell? Do I assume it's an S if there's no R? I'm switching to your recommendation. Neuropathy pain is hard to live with. I don't have diabetes tho thank goodness. Thanx for the info!
@@JasonBuckman Jason is right, Jeanne: 50% S 50% R. Isolating the useless S isomer would be a waste of money and costly and no company would bother. I personally think RS-alpha lipoic acid is fine. Just double the dose you would plan to take if you were taking straight R-alpha lipoic acid. MAYBE the S competes a bit with the R, but since most of the research showing that alpha-lipoic acid works was done using RS-alpha lipoic acid (like you have), I can't imagine that the S form blocks the R form to a very great degree. But you can get straight R-alpha lipoic acid if you disagree and feel it would be more effective.
Thanks for the Alpha lipoic Acid information ! This is really a eyes open because most of the brands in Jamaica are S types or no indicator of which type on the back of the labels. A matters of fact I haven't never seen any of the R type as you suggested therefore I would really appreciate if you could share with me a few of the R types pictures so that I can choose from. Thanks once again your faithful Dr.
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Jarrow has an r-alpha lipoic acid, but their other ALA supplements are 50% r, 50% s. This is called a "racemic mixture" and most of the studies showing ALA works have been done using THIS form. I don't think there is any good reason to pay extra for r-ALA (although you need twice the dosage of racemic ALA to equal the same dosage in r-ALA). That said, there is research showing that instant-release ALA is better absorbed than continuous-release ALA. Some of Jarrow's ALA (their "Sustain") are a combination of instant-release and continuous-release in a bilayer tablet. I think you're paying extra for this for no good reason to get a supplement that is less effective. nutricost has ALA you may want to consider: great value for the money, but any reputable supplement company's ALA should do.
For sure, usually this means 50% of the effectiveness though. Im not saying its completely worthless, just that the S-type does not function all that well. and consider half the dosage then. 😊
it causes insommnia for me. I don’t think I need it as I don’t have any illnesses. I watched this and purchased it and started taking it but I could not sleep under the influence. I already Eat lots of the vegetables you mention so maybe I took a supplement without needing it.
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Does anyone know about [so-called] bio enhanced or bio actaved ALA? Or is straight R-ALA 600 mg. all one needs for macular & cataract eye health & prevention?
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Alpha Lipoic Acid (Antioxidant beneficial in Neuropathic pain, Diabetes.
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How to get rid of burning tongue? How to have a healthy tongue? Thanks in advance.👣❤🌿
Could you do one on nail fungal infections
Thank you! I have just come across your channel and had found the above vlog extremely insightful. I live in South Africa and CDS has become a buzz word. Do you have any knowledge on this and if you do, what is your take on it?
Thanks for sharing this video it confirms wihat I know of alpha lopoic and promoting eating of veggies good presentation up to promoting eating any animals it’s always disappointing when promoting health they throw in eating meat or fish…
I went on Keto diet and OMAD intermittent fasting. All my neuropathy pain went a way, prior to that I took r-lipoic acid as the same brand you recommended. I took 600-1200, it didn’t work as well as changing my diets. X-out all the processing food, refined carbs and sugars and omega- 6 oils. Straight Whole Foods and intermittent fasting! It also removed my osteoarthritis. It took effective within 21 days. I will continue with this diets and fasting the rest of my life. I love it. Let’s food be Thy medicine!
please tell which type of keto diet helps you there are a few. thanks
Which brand of R-alpha Lipoic acid are you taking? Thank you.
I am using HMS Nutrition LLC for R-Lipoic Acid.
As for Keto diet, I am not a vegan Keto. I eat animal products , vegetables, nuts and seeds and combine with intermittent fasting. I eat twice per day with 18:6
Intermittent fasting for 5 days, then I eat one meal per day (OMAD IF) for the last two days of the week. I am on this Keto diet and IF, my body needs a lot of vitamin B complex and electrolytes. I drink two tsps of moringa powder daily to remove any oxidized LDL and provides 92 essential nutrients. I also take raw vitamin B complex, B12 has to be form methylcobalamine, not cyanocabanomin ( manmade). I drink 1 scoop of electrolytes powder per day. The 4 main electrolytes are potassium, sodium, magnesium and calcium. Everyone needs 4,700mg per day and sodium is half of that to get the cells to be hydrated and functions properly. It’s hard to get potassium. Eat bananas, it has a lot of starch and sugars, it’s not a keto friendly. Avocado has 76% fat, 16% carbs and 5% proteins. I eat two avocados per day. I also eat 1-2 tablespoons of northern white beans, it has the richest source of potassium, but it’s high in carbs.
My advice is anyone decides to get on any special diets, needs to do a lot of research and understand the body needs.
I recommended to watch the videos from Dr. Sten Ekberg, Dr. Eric Berg and Rayan Taylor. These ppl are very knowledgeable about nutritions, diseases and cancers.
If you do the intermittent fasting, it’s a must in any diets you choose. Keto diet, you trained your body to use fat for fuels. Sugars damaged the liver, glucose damaged the brain cells. Use MCT oil while you are fasting, it feeds your brain, you feel the fullness and no cravings. Eat all your calories in one hour, then your next meal is at least 6-8 hrs window for beginners. Also, take 1-3 tsps of organic raw unfiltered apple cider vinegar in a cup of water 20-30 min before each meal.
I enjoyed eating like this very much. My body prefers fat over sugars and carbs. I have a lot of energies, clarity, focus, well sleep and happy.
I did the same thing. Then went to an idiotic neurologist who tested me for neuropathy, and she said, "you don't have a neuropathy. Your nerves are healthy. But we'll do an mri just to make sure" I say idiotic because she was convinced neuropathic symptoms can't resolve with diet changes. The symptoms resolved when I changed my diet to mostly non-startchy vegetables and meat. I add in bits of yogurt and quinoa here and there, and a splash of berries and statchy veggies. Bits because these are quick to raise glucose levels and the primary key to fix neuropathy is eliminating surgar. Salt is low with this so I've got LMT electrolyte powder on the way, along with drinking chicken broth in the morning here and there. Keto will elevate your LDL, and make you risk gallstones, so I would recommend a slow switch to keto and not a drastic one. You fix one problem and it starts another. Prevent the gallstones by drinking 2.5 litters of water. I wouldn't do keto without research or with the guide of a doctor who can test your electrolytes cause you can mess yourself up pretty easily.
@@bleeblah3583 Yes to all of that... I would just add that from my research, I suspect ACTUAL KETO is very good for some specific problems and can be used as SHORT term treatment. But I have come to believe that most of the LONG TERM benefits attributed to Keto are actually derived from the "LOW-CARB" part of the diet and IF. Striving for CONSTANT DAILY KETOSIS may turn out to be a LESS optimal as a lifestyle.. All The Best, Stay Well : )
I was taking the cheap, s type crap, for several months -- zip, nada, nothing. I heard about the R type, got it the same day. Cost more!! But the very same night I took one pill of the magic stuff: a miracle. I could walk across the floor without enormous pain.
Thanks so much for getting the word out.
KISSES & HUGS!!!
That’s what I been researching. S&RS are synthetic or the S cancel out the R I agree it’s not cheap
But considering what I have done to my body. It’s a bargain if you feel good.
@@edwinrodeowhat brand have y been taking? Thanks😊
@@shar7508yes. What brand please
Thank u since April I have had a lot of nerve pain and my feet are saying “don’t walk on me”. I so sad because I’ve always been athletic. I’m starting this vitamin now so I pray it work for me.
Please look into Viitamin B 1 ( Benfotiamine) MEGA DOSE for example 1200 plus 2x daily - it is not harmful‼️ PLEASE read reviews and you will be able to resume your active lifestyle✝️🧡
It helps tremendously! Get the correct one...R Alpha Lipoic Acid. You are in my prayers!
@@traceytansley1659hi,for how long you have used r ala? Actually m having pain in my legs and getting tingling...do this supplement wrks?
Congrats! You are the second doctor to mention the two types of ALA. I just found out what I've been taking probably has the type S in it. They are also mixing the two kinds to save money. Some call those a third type but it's really just the two. They should have to stop selling the type S. Type R is the natural kind.
I think the process for manufacturing synthetic ALA produces equal amounts of R (the naturally occurring one that works) and L (doesn't exist naturally, and won't work) which are not easy to separate, and that's why both together are cheaper.
@@red-baitingswine8816 Who cares if it's harder to make. The problem is the synthetic ones blocks the natural one from working. It should be illegal to use the synthetic kind.
@@stevenw4549Do you really think a company could sell a mixture of half R (active) and half S (inactive), if the S blocked the R? Feel free to pay more for the pure R isomer..
.
The video gave no evidence that the S blocks the R - no studies, let alone controlled experiments. I suspect it's common knowledge among professionals that the R/S mixture works just fine.
@@red-baitingswine8816 They can and do. It is unethical. I used one for at least two years before I found out. There are other videos that specify the difference and that S blocks the R type. S does nothing so you pay for a worthless product. These companies only care about profits. They don't care if their product works or not, as long as you will buy them. Most people just think ALA is ALA and don't know about the differences. That is how those companies get away with it. I would rather pay a bit more for something that works as opposed to paying less for something that doesn't. If it doesn't work, then you might as well save your money and take nothing. The kind I buy now says on the label that it contains no type S and only contains type R. I've only been using it recently and can already tell an improvement in my neuropathy. Especially in my left hand which was the worst. Don't count on professionals knowing the differences. My doctor was the that suggested my trying ALA and he never mentioned the different types. They don't concern themselves with details about supplements. They concentrate on drugs. Through reading, I learned that because I take Metformin, I should be taking Ubiquinol which is active CoQ10 because Metformin depletes it. So I ask my doctor about it and he said yes I should be taking it. Yet he had not told me to take it before. I had to do my own research. So-called professionals know little about supplements.
The other doctor said there is a third kind. It is a mixture of the R and S type, which you may think is ok but still the same pro the S type cancels are benefit of the R Tyra.
Such a refreshing, non-promotional video on R-ALA, plus the links to getting the least expensive form! Thanks Dr. Tom
Thanks for the great response!
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ALA helps me a lot. If I don't take it for a few days I get horrible nerve pain in my feet that wakes me up at night.
R-ALA has helped me hugely with bad neuropathic widespred pain. I have/had tingling, numbness, deep pain, deep internal and external itching, shocks, severe nerve pain, and water trickling sensations, sensitive "sunburn feeling" skin on my back,shooting pains, stinging pain everywhere. My right upper outer thigh bringing me the very worst agonizing pain the longest..it is now numb, as are other areas on my body. Way less heat sensations felt ( not sure about cold sensations), on my legs, chest, back. Horrible heavy legs feelings like there is cement inside them. Originally (not knowing) I had the good R-ALA which was helping, then when i went to purchase more, they werent carrying that one anymore, so I bought a different one, which turned out to be RS-ALA and i noticed my pains returning. By the time i had almost finished the bottle, i discovered a medical video much like this one, explaining the differences of Alpha Lipoic Acid, I checked my bottle and sure enough, i had bought the lousy kind the second time. I ended up ordering the R-ALA on-line and have been back on the good one a few weeks now, again HUGE IMPROVEMENT I am feeling...its working! Thank you!!! ❤
What brand? Thank you 😊
Thanks for this information, for those taking ALA, make sure you take it in the morning as this may cause insomnia if you take it before bed.
Thanks for thinking of others. You solved another problem. HalleluYah
Oh thats why I feel nervous tension with this .. I was told vit depleted B1, a calming vitamin... And I am deficient in B1. I take Benfotiamine to calm my nerves
@@francinegryspeerdt18 Yes a nurse prac told me to take like a vit B-50 w the alpha because it depletes the Bs.
@@skybox-101 B 50 supplement ? What is that? What do you mean? A B complex or a B 5 supplement? Thanks a lot for answering.
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Very good motivational inspiration!!! Here's the thing, through my own personal experience, I have come to find that taking the Ayurvedic approach of counter-balancing, I utilize 1000-2500 mg Bitter Melon before each meal, way cheaper than buying fresh veg. Further, I've found that if I eat like, pumpkin seeds in the evening for their magnesium, my feet burn, so I can either take the bitter melon before I eat, or take Chromium Picolinate to neutralize the pain. Berberine (600 mg.) is also great before eating. Experimenting with each of these gives one a lot of options that actually work to eliminate the pain ASAP!!!!
It did help a lot for my sciatica for less than a month, to the point that I stopped taking it, for awhile already, but pain is kinda coming back!
Thank you for describing the difference so clearly.
I ordered some of the s type last night, and now I’m going to cancel my order.
We appreciate you watching and contributing Lisa!
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My autistic brother suffered a stroke on Nov 2022, started taking R- Alpha Lipoic Acid, along with Magnesium and B12 vitamins, and he is know walking and talking more and more (10 weeks post stroke).
that is amazing! congrats to your brother! DID HE CONTINUE TO RECIEVE HEALTH BENEFITS FROM IT LATER ON?
What brand? Thanks😊
You can take this compound at much higher levels than what is recommended on the supplement label from jarrow or any other company. My opinion is that time release works better because it only sticks around in the blood about an hour and then a little more but not very long. You can read up on this. If you're not getting results, it is safe to take much more. I take one to 2,000 mg a day sometimes when I'm really pushing my boundaries with overtime work. You have to spread your doses out throughout the whole day when you take much larger amounts. I've done this for years. It keeps me from getting sick and keeps me looking young.
Brian what brand and where you get it
@@johngoh767 Jaroow Formulas sustained release alpha lipoic acid
You are one of few docs to expose this scam on ala.Thanks
Pack aru, we appreciate you watching and contributing!
Let us know if we can cover any future topics for you.
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I like how you mention cost in today's economy.It shows me that you are a caring person.
Thank You.
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If possible, we would appreciate a quick rating (hopefully good), and it makes a HUGE difference for us!
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Make sure to get the stabilized form of R-lipoic acid.
The Cyclodextrin kind is the best.
I've been taking it for a month and it's helped relieve the nerve pain I had in my back as well as relieve the numbing tingling I had in my thigh.
What brand has the cyclodextrin. Thank you.
PRODUCT LINK?
I take alpha lipoic sustain with biotin for vegan Jarrow brand. I’ve been taking for about 4 years. Took for neuropathy but to my pleasant surprise I no longer have hypoglycemia symptoms which I had my whole life for me alpha lipoic is my miracle 🌈🌞
I’m excited for you and I’m hoping it helps me as much. Just bought this brand 2 weeks ago. Jarrow is the only brand I’ll buy because their products are legit. So fare I’ve noticed a huge energy boost. I feel more calm, not having anymore heart palpitations and the tingling I get in my legs and hands has almost disappeared. I am pre-diabetic. Can’t wait to get blood work done to see what my numbers are after taking these.
@@boomerang0101 it may be, but I’m seeing major improvements with my body already so I’m going to still with this. I’ll keep your suggestion in mind though. Thanks 😊
@@boomerang0101 Jarrow Formulas Alpha Lipoic Sustain with Biotin. It says you can take 1 300mg pill 1 to 2 times a day.
I take two a day equaling 600 mg a day. I do one in the morning and evening. So far I’ve noticed huge burst in energy, no tingling through hands and feet, more calmness and I feel like it’s made my stomach feel way better. It’s still early so there may be more.
@@boomerang0101 oh also I am out of my add meds and can’t get a refill because the pharmacy is out of stock. This is helping md make it. Without my add meds my focus is off and I get very fatigued. It’s hard to get through the day. This gets me through the day easily and I do feel like I have been focused on it. Starting to wonder if I need my add meds anymore.
@@boomerang0101 one night I felt like it did, but I think because I took them to close together. I took the first one later morning. I was going to go down to one a day after that but something told me to keep taking two a day but try to take the first one as early as possibly.
I really appreciate your study on this. I am going to incorporate more spinach and broccoli in my diet. Thank you so much, Dr. Tomasz!
You are a great fan, and we appreciate you Jenny!
ruclips.net/video/qO9FsUph_Wk/видео.html These foods might be a good option as well!
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I had no idea there was good and bad alpha lipoic acid. Great video
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I have nephropathy in both of my feet after hip surgery. ANA has controlled the pain, at 600 mg x2 daily. If I miss a doses I feel it.
Thankyou, i am finding i have issues too after hip replacement surgery. I just brought the R ANA Capsules, 300mg - says to take one daily but after hearing you i will invease the dose
Thanks!
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Thank you! I have been taking the S Alpha Lipoic! No help and fooling myself because sometimes I had no pain but most night didn't sleep much because pain would wake and keep me up. I'll eat more greens and get the R-
I love spinach stirfry
Garlic and some sweet chillie sauce on it
Same with broccoli
That's sounds delicious 😋
But you're absolutely right, you just have to find a few go to meals!
Sweet chilli sauce is delicious but it is sugar !
Just knowing the chips will give me a horrible stomach ache from the grease cures my craving (bad oils w/ Omega 6 not 3, high temps break it down to toxic). Poor nutrition also causes cravings. Keto has helped me so much with all that.
Thank you very much
You are only the one tell the true regarding type
R and S.
Thank again Doctor.
You’re a hoot doc - I’m taking 1,200 mg per day to help with my neuropathic pain
Does it work?
It does for me
@@ClassicalLiberalWarrior sadly it hasn’t for me
@@gloriasaliba3395 Sorry to hear that!
Amazingly...it MIGHT be lightly helping me. I've inconsistently used about 300-600 mg./day of stabilized R-ALA for 20 days or so and it SEEMS to help a touch with foot numbness.
Are you using stabilized and pure R-ALA?
@@ClassicalLiberalWarrior that’s great news yes I am - what brand are you taking?
I'm a chemist interesting analysis, never thought about the S-form being an antagonist.
It is difficult to 100% lock this down in all honesty, but this is a proposed theory. At the very least even in that case you are getting 50% of what you are expecting to be getting. Let me know if you can find anything extra 😊
I did spend a decent about of time trying to confirm some of these claims and the evidence is not overwhelming one way or the other.
@@DrTomBiernacki kind of thing that would be easy to test in mice, give 100% s or r, maybe in a genetic model that is susceptible to oxidation stress
I contacted a supplement manufacturing company with this question about R vs. S alpha-lipoic acid, and they said all the studies that indicate it is effective in treating neuropathy have been done with a racemic combination of R and S. They stand behind that research. Hard to tell who to believe. My own oncologist said it didn't matter.
Lots of confusion in these comments, so let me try to clarify. The synthetic racemic mix of RS-ALA is not S canceling out R activity/bioavailability. Taking R-ALA is certainly active and bioavailable, but the RS-ALA mixture provides 50% of the active R-form and the S-form mixed in may in fact prevent the R-form from polymerizing (i.e., making it inactive). However, the relative effectiveness of pure R-form vs the RS-racemic mixture has not been quantified yet (but that doesn't mean the S-form is cancelling out the R-form activity). Here is the quote from the article (see also link below): "These results suggest that the R-enantiomer would be the most appropriate form to provide as oral supplements; however, S-LA in the racemic mixture may prevent the polymerization of R-LA and thereby enhance overall bioavailability. It has yet to be established whether R-LA, its salt form, or a racemic mixture would be best to use in future clinical studies." (see www.ncbi.nlm.nih.gov/pmc/articles/PMC2756298/)
the radical scavenging and chellating properties of ALA dont matter no matter if its the R or S form but the other effects such as the metabolic effects for blood sugar do matter.
If you are taking it for diabetes then you need only the R form but if you are taking it for its radical scavenging properties then it doesnt matter.
I was having neuropathy. And have no reason. All test was normal non dibaetic. I tried every medicine nothing works. Finally i tried alpha loplic acid. 600mg was giving me vertigo. I go to 400 mg now months and my neuropathy is very much reduced. I feel like i was not having it
You must have brain MRI. Unfortunately if brain have lesions it leads to MS with such symptoms though all blood test and cervical X - Rays are ok.Same is with my case
Thanks for sharing. I will buy the R. Have a good rest of the day.👍👣❤🌿
Thank you so much vibrant Spirit!, Very appreciated and we wish you the best of health!
Raw spinach lectins and oxalates
Thanks! I love broccoli and spinach. Am growing both too.
But I also take R-Alpha Lipoic Acid.
Is it of any help?
very helpful in knowing which type of Alpha Lipoic Acid is best!!! thank you
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does this reverse the damage that's already done, or does it just lessen the symptoms as long as you're taking it?
San Antonio Neuropathy Center they have a ytube channel and an office in Texas
I drink all my greens veggies... I put it in a blender and drink it every day. I am feeling much healthier....If You can't eat it drink it. 👍
That sounds good what do you put in?
They are the best for diabetic neuropathy. It works for me and I have been able to carry a cup of coffee. Neuropathy come to me because of Metformin because it kills vitamin Bs.
Some sellers sell ALA without expiration date and online sellers do not return them.
Thanks Dr. For your excellent explanation
You are a great fan, and we appreciate you Ismael!
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@basmaali944 Your Mom has consumed most of my energy.
TY for differentiating between the two forms!
Thank you for the information.God bless you.
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THANK YOU for listing good quality sources! I need the good fish oil also. Have been wasting a lot of $ and time with tons of low quality vitamins from a well known online supplier.
Follow Up to my Post - I called the company and asked what my supplement was, she said 50/50...I guess I won't be buying that any more, as I'm 77 and want the full affect of the pill. #1- You're never too old to learn #2 - We learn something new every day #3- It's up to us to make the necessary switch to get & feel better....Wishing all here a Happy, Healthy New Year in spite of the bumps & challenges we will face...Are you spiritually ready ?
Most of the research showing ALA works has been done using the racemic 50% mixture that you have. I think the doctor is wrong about r-ALA being much better, although it is twice as strong per mg, that much is true. I would, at least, use the supplement you have until a new r-ALA supplement arrives at your door if you do decide to switch and pay the higher cost.
@@christophdollis1955 - Thank you for this information, this neuropathy came about from the sciatica attack I had in Jan...I would like to repair this numbness as quick as possible, it's an uncomfortable feeling from my knee on the outside down to my foot. I will continue and finish what I have, will try one bottle of the r-ala, and then switch back..I want to at least try it and see....not a comfortable un-feeling if you know what I mean...Happy New Year to you and yours...may it be a healthy 2023...
@@Twins0302 You're welcome.
Incidentally, benfotiamine (a synthetic vitamin B1 supplement) is a prescription drug for sciatica in Germany. It, or sulbutiamine or TTFD, two other fat-soluble forms, legit may help.
Benfotiamine most reliably gets to the peripheral nerves: sulbutiamine and TTFD get to them peripheral nerves, but they pass the blood-brain barrier moreso than benfotiamine (which offers certain benefits, especially for some people's depression, energy, etc.) and so probably a bit less of them get to the peripheral nerves.
I like all of these forms, and mostly use sulbutiamine personally.
@@christophdollis1955 Hi Chris, a few Q's - how do you know about this B1, & isn't non synthetic better, I have been taking B Complex.? Q @2-what is your background....I am still taking Gabapenten 300 mg at lunch or dinner...once a day...just asking, I do research but you know quite a bit...
@@Twins0302 Synthetic is useless! Toss them.B vitamins have to be taken all together as in nature - they are created all together - so get a B complex or OD on nutritional yeast.
I thought R α-lipoic acid was unstable alone and needed to be combined with S α-lipoic acid to be functional as a supplement, so unless the product specifically states R α-lipoic acid, your getting a 50/50 blend according to a nootropic experts
Your right, This guy has no clue
I have NOW ALA and contacted them - since they put nothing on label. They said it was a combo of both - so you are saying that is the best way to take it vs taking R+ exclusively?
@@tracyau9122 No, I'm saying if you buy any ALA your likely getting both so you can buy the cheaper version ... I don't know who manufactures this stuff but there are mostly in a blend, it just the labeling that changes. I'll see if I can find the resource I used - ruclips.net/video/6sXT6Hnt3Bc/видео.html
@@iewauhedoc9970 awesome thankyou so much - i'll check out the nootropics youtube
Hello!! It’s my first time taking alpha lipoic acid and I realized that none r or a or s is written, just THIOTACID, on the label just ALA. In my country no other alternative. Is this the right one I am taking!! I am suffering from leg numbness, lack of toes’ mobility & unbearable pain under foot - just right leg. The neurosurgeon recommended this…… thank you
Thanks for the great response Lisa!
Realistically its just a little less effective potentially, don't ignore your doctors advice if that is what is available!
ruclips.net/video/tL-Vj0wODaw/видео.html
This video may help as well!
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Thank you for this. I did not know the difference.
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I take nutricost ala 600 mg 2 capsules daily. Is this a reliable product?
Yes.
Most of the research has been done on racemic 50% r-ALA 50% s-ALA such as the nutricost brand. You need twice as much of the racemic rs-ALA as you would r-ALA, but it's effective and economical and also more stable than r-ALA on its own. Instant release also seems to be MORE effect than continuous release.
*"While the abstract of the Evans et al. paper mentions the change in Tmax (the time to maximal plasma concentration), it fails to disclose that the plasma concentration at that maximum (Cmax) was 45% lower in individuals taking the controlled-release lipoic acid compared to those taking the quick-release form. Additionally, the total absorption, based upon the area under the curve (AUC 0- 24 hours), was reduced by 42%." /// "While the abstract of the Evans et al. paper mentions the change in Tmax (the time to maximal plasma concentration), it fails to disclose that the plasma concentration at that maximum (Cmax) was 45% lower in individuals taking the controlled-release lipoic acid compared to those taking the quick-release form. Additionally, the total absorption, based upon the area under the curve (AUC 0- 24 hours), was reduced by 42%." /// "Furthermore, the modest oral dose of 300 mg/day of oral lipoic acid (racemic) in metabolic syndrome patients statistically improved endothelial function (measured by flow-mediated dilation), while decreasing the pro-inflammatory markers IL-6 and PAI-1 (plasminogen activator inhibitor-1). 10 Other positive clinical trials have also been reported using oral, racemic 'quick-release' lipoic acid for a variety of other health conditions in recent years.11,12,13,14 These data suggest that standard forms of lipoic acid do not suffer appreciable declines in clinical efficacy when used orally, compared to similar doses delivered intravenously and are currently the standard form in clinical experimentation and practice." /// "while there is abundant clinical research on the racemic form of lipoic acid, we are not aware of any published clinical trials, in humans, using R-lipoic acid; or any comparing R-lipoic acid with the RS-form. Second, since the R-form is derived by separating the two enantiamers, it is much more expensive than the racemic mixture. Without clinical data to suggest the effective equivalent dose, it seems premature to suggest the wide use of R-lipoic acid in clinical practice, and difficult to justify its use from a cost-effectiveness stand-point. Until future studies are performed and/or technological advances reduce the cost of R-lipoic acid, the use of racemic alpha-lipoic acid seems to be the most cost-effective choice at this time."( [excerpts from *"Technical Report-Time-Release Lipoic Acid: More Marketing than Data, July 2007"* from +POINTS INSTITUTE,+ Director: Thomas Guilliams, Ph.D."]
Is there any chance R Lipoic acid helps Sciatica…..pinched nerve issue that my husband has for the first time and in so much pain.
I am surprised that you recommended products with di-calcium phosphate that is known to inhibit absorption of other nutrients.
I make green smoothies with pineapple, ginger, lemon, spinach, water and a little pineapple juice. It is a good way to quickly get the greens. I don't have a fancy expensive blender, I use a food processor and then an emulsion mixer. I was skeptical but it actually tastes good.
Thanks for confirming what I have heard about R Alpha Lipoic. Can you tell me whether it is absorbed best with food or empty stomach? And is the NA sodium added good for it's absorption or shall I steer clear of the combo? Thanks again!
Thanks for the great response Sandra!
Som reports state that there is a 40% better absorption on an empty stomach. It is also important not to cook the vegetables as it does ruin the alpha lipoic acid. I do believe most stable formulations are sodium as it is a negatively charged acid otherwise.
Let me know how it works for you!
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It's water soluble, so take it on an empty stomach with a glass of water
@@scottharm3932 It's actually both water AND fat soluble, which is one of the things making ALA so excellent. That said, it's absorbed with or without food, but seems to be better absorbed on an empty stomach and you're right about that.
Gud pm doc.alpha lipoic acid is for only diabitec neuropathy?if you are alcoholic neuropathy can i use ALPHA LIPOIC ACID?
There are 3 forms of Alpha Lipoic Acid on the market:
R-Alpha Lipoic Acid.
S-Alpha Lipoic Acid
RS-Alpha Lipoic Acid.
The R-Alpha Lipoic Acid is the only pure form and costs a lot more than the synthetic ones, which are a waste of money!
It is vital that YOU high-light this fact to your viewers!
Which one best
What is DL-Alpha Lipoic Acid? Thanks.
Is the DL- Alpha Lipoic Acid the same as S-ALA? ( I tried DL to start because it was readily available) and all it did was cause an unpleasant urine smell, suggesting to me that it is not being absorbed at all, but just being flushed out as fast as it goes in. Then I switched to R-ALA (pricier) and developed a crazy itch all over my body even at only 200 mg/day. What gives??? I was taking it for neuropathic pain- not diabetic.
How do I get? And can it help arthritis? If not what do I take for arthritis in the hands early morning is the worst . Thanks very much.
Wow, we appreciate the kind words and your watching.
Check the show notes or search it on Amazon.com. Doesn't have to be expensive!
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Thanks so much for important information
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I appreciate if you can also give the the brand of the R ALA you advice, thank you very much and God Bless you.
Which brands are best ?
The link to the ALA has the s form! You should correct that link for nutricost. It is not the correct form
I take Jarrow Formulas. Any supplements I take are by Jarrow because they test their products. Anything I’ve ever taken from them works. Btw I’m not in the market to sell this brand. I just love their products because they are high quality.
Hi,...I follow you & thank you for your professionalism & for sharing....keep up the good work. 😃
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Chia seeds good number of ALA ?????
Can i drink alpha lipoic acid together with together with vitamin k2
Ian Vince Cruz, thanks for the great response!
There are two schools in this topic. Some believe that due to lack of any empirical adverse effect ALC and K2 may be taken at the same time. However, due to theoretical interaction of ALC and K2 others recommend taking one in the morning while the other in the evening. Both methods are in use and there are practical and theoretical arguments supporting both way of taking ALC and K2.
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All the best to you Ian!
yes! thank you thank you thank you! Needed that info on which typle of alpha-lipoic acid is synthetic! R-a lipoic acid is Natural yayy!! i'll let you know how is goes!
Should the r-alpha lipoic acid be taken in a single dose (600mg x 1), twice a day (300mg x2), or three times a day (200mg x 3)?
Divided doses, morning and mid-morning
I jave Mercury filling
Cam i take it
I’m surprised you recommended one with both R & S in them since the S cancels out the R!
I read comments on Amazon. There are various ALA bottles not labeled as R, just ALA. People are reporting good results from these supplements. So just assuming they don't work may not be a good assumption.
I'm taking the NOW brand of Alpha Lipolic Acid. It's a capsule. I looked on the chart and it doesn't have the R or S before the name. It's labeled as..Alpha Lipolic acid (Granules)600mg.
Am I wasting my money?
How can we "stabilize" the lower cost R-Alpha Lipoic Acid Supplement?
Thanks so much for this video, I started my a-lipoic acid treatment supplement, I already take spinach greens, b. sprouts,..etc. in my greens smoothy.... so my bottle doesn't say R- or S-...I'll call the company this week...
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It would say if it was R before ALA on the bottle.
The best is R- alpha lipoic acid .
I started with pain in the pancreas area, and after weeks, the pain spread practically to my entire back, mainly under the shoulder blades, the time came when it was unbearable and I couldn't sleep, I heard about R Alpha Lipoic Acid, and I investigated the correct dose for my neuropathy, I started taking 600 mg per day, and after a few weeks, the back pain practically disappeared, but I still had pain in the stomach area, so I increased the dose to 900 mg, and the pain on the right side The stomach area also disappeared, now, I'm just waiting to no longer have pain, and this happened in only two months, so it probably won't work for everyone, but in my case it has been a miracle, and I didn't have than spending money on doctors or hospitals, I have only spent a little more than $40.00 Dls, and I am extremely happy, so I do not agree with this Doctor's opinions, and like me, there are thousands of people with satisfactory results.
how long did you have neuropathy and back pain before you started taking alpha lipoic acid..did you take any other supplements... ruclips.net/video/Kzl0BOjLV38/видео.htmlsi=Y-cHQCAt1giSckDT
Great video Doc !
I’ve been taking the alpha lipoic acid for about 2 months now and it hasn’t done anything..so now i ordered the R-alpha I will give that a shot …I’m so miserable
not true i take regular alpha lopoic acid not the r one it helps me alot for 2 years for my depression much better then anti depressants helped me in the past and it helps alot for my nerve pain in my feet
I'd add something - everybody should check - R-ALA should be stabilized - than is multiple times more effective! If is not written on the package - probably isn't! Also - I'd like to ask you - is it same thing with pyridoxine - HCl and pyridoxine - 5 - phosphate. Are they compet too as the S- ALA and R- ALA ? Is it safe to take them both? I use 50 mg of P-5-P and 10-12 mg of P-HCL 'cause P-HCL is, almost,in every suplement... I enjoy to watch your videos - some of them many times - it's very helpful. Greetings from Serbia!❤
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I got hand and finger tremors from taking alpha lipoic acid (S+R combo). Did anyone have this issues?
Dr, really enjoyed yr great presentation. A chiropractor recommended 600 mg ALA 3 times a day. I feel thats quite much, do you agree, ? I'd appreciate yr opinion
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Alpha Lipoic acid has been tested on mice and apart from the benefits, tests showed that the lifespan of the mice who were give ALA was decreased by around a third.
You forgot to mention that some brands are labeled RS alpha lipoic acid just to confuse people into buying that brand.
I love potato chips but they got too many carbs.
I bought R-ALA and then read it can take mercury from the amalgam fillings and possibly move through the blood brain barrier and get deposited into the brain. So I've been afraid to try it. As I am a type 2 diabetic. Anyone else heard of this?
the best thing u could do is to have all your mercury fillings removed asap!
Yes look up Andy cutler chelation. Do not take Ala off it’s half life or with amalgams
I have heard this too.
Thank's for your videos love all the information from you learning things,so I checked my bottle I have and it does not tell me "r" or "s" so what's up with that?
Thanks for the great response!
Usually this means its not pure R 😀
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@@DrTomBiernacki Thank's,which leaves me surprised,paid good money,I will do diligence and buy from a place that it has the "r".
Thank you so much.
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Check with my dr? He criticizes me for using C, D3 and zinc. People use ALA to detox heavy metals but they have to take it in the night too.
Consider it a necessary medical disclaimer 😊
I am Australian i have diabetes fibromyallga i have had a stroke November 2019 can you please help me
Tried R-ALA (only 100mg) and it gives me a terrible case of heartburn. Don't know what to do, bc I really want to get off gabapenten.
My experience is to take ALA with a full meal. Not a snack.
If I'm not mistaken the S type doesn't act against the R type - it just doesn't do anything. The chemical process used to manufacture synthetic ALA produces equal amounts of R and S, which are not easy to separate.
.
Anyone who claims that the S type acts against the R type needs to cite a scientific study with those results.
.
Of course anyone is free to spend the extra money to get the pure R type.
My supplement doesn't have the R or S on it. How can I tell? Do I assume it's an S if there's no R? I'm switching to your recommendation. Neuropathy pain is hard to live with. I don't have diabetes tho thank goodness. Thanx for the info!
If it doesnt say R then its S
If it doesn't say, it's 50% S, 50% R
@@JasonBuckman Jason is right, Jeanne: 50% S 50% R.
Isolating the useless S isomer would be a waste of money and costly and no company would bother.
I personally think RS-alpha lipoic acid is fine. Just double the dose you would plan to take if you were taking straight R-alpha lipoic acid.
MAYBE the S competes a bit with the R, but since most of the research showing that alpha-lipoic acid works was done using RS-alpha lipoic acid (like you have), I can't imagine that the S form blocks the R form to a very great degree.
But you can get straight R-alpha lipoic acid if you disagree and feel it would be more effective.
Can’t find the real thing in South Africa. If someone knows the brand, please advise. Thank you
Thanks for the Alpha lipoic Acid information ! This is really a eyes open because most of the brands in Jamaica are S types or no indicator of which type on the back of the labels. A matters of fact I haven't never seen any of the R type as you suggested therefore I would really appreciate if you could share with me a few of the R types pictures so that I can choose from. Thanks once again your faithful Dr.
I'm in Jamaica & I'm trying to find the R-Alpha. I'm checking amazon. Did you find any?
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Amazon is probably the best bet!
Jarrow has an r-alpha lipoic acid, but their other ALA supplements are 50% r, 50% s. This is called a "racemic mixture" and most of the studies showing ALA works have been done using THIS form. I don't think there is any good reason to pay extra for r-ALA (although you need twice the dosage of racemic ALA to equal the same dosage in r-ALA).
That said, there is research showing that instant-release ALA is better absorbed than continuous-release ALA. Some of Jarrow's ALA (their "Sustain") are a combination of instant-release and continuous-release in a bilayer tablet. I think you're paying extra for this for no good reason to get a supplement that is less effective.
nutricost has ALA you may want to consider: great value for the money, but any reputable supplement company's ALA should do.
Try health food store.
Mine has no a or s. On bottle
Hey, spinach tastes good; especially when you're hungry.
Dr I'm taking R Ala bat I'm having hair loss can you please give me any advice
All clinical trials used ALA not R-ALA .So synthetic form is also effective.
For sure, usually this means 50% of the effectiveness though. Im not saying its completely worthless, just that the S-type does not function all that well. and consider half the dosage then. 😊
Thank you, and have a merry Christmas and an amazing New Year! 🙏😊
it causes insommnia for me. I don’t think I need it as I don’t have any illnesses. I watched this and purchased it and started taking it but I could not sleep under the influence. I already Eat lots of the vegetables you mention so maybe I took a supplement without needing it.
I'm afraid of that happening to me. NAC does that to me. How much did you take and at what time?
You are to take it in the morning
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The bottle I have (Nature's Bounty) states that it is 'DL-Alpha-Lipoic Acid'. Is this undesirable?
Mine too
That was 5 foods. what are the other two?
Does anyone know about [so-called] bio enhanced or bio actaved ALA? Or is straight R-ALA 600 mg. all one needs for macular & cataract eye health & prevention?