Thanks a lot for your kind words...Your encouragement and support means the world to me...I cannot thank you enough...I would just like to politely request that you share my videos with others...It really helps! Thanks a million!
Your videos are great! I've been struggling to keep these enzymes straight as I study for the Chemistry ASCP exam but these videos are helping a lot. Thank you very much!
@@MedicosisPerfectionalis I'm interested in bone alkaline phosphatase, which I gather is different to blood Alp. My bone alp is 23 so do you have a video about low bone Alp?
Thank you sir but you don’t explain the mechanism of high ALP in blood in these disease why alp increases in biliary disease? Is it because of destroying of cell which releases alp in blood or some other mechanism?
Hi I had a question, if alk phos is low but zinc is good range & copper plasma is on the low side (76 on a scale of 70-175mcg/dl) what could this indicate? Thanks
If you pay attention in Biochemistry, you notice that the first step in any carbohydrate metabolism is phosphorylation “e.g. glucose will become glucose-6-phosphate”...Why is that? Because if glucose alone entered the cell, it can diffuse back to the extracellular fluid (which renders catabolism impossible because we can’t pin glucose and fix it inside the cell so that we can perform our chemical reactions on it), so, phosphorylation fixes stuff inside the cell and prevent them from leaving...That’s why my mnemonic is “Phosphorylation Phixes” which means phosphorylation fixes. Hope it helps!
My alkaline phosphate has been over nearly 200 for a year. My bones are extremely thin and fractures are now near 13. This began a few years ago with the fractures when we had mold poisoning from our house. I have an appointment with an Endocrinologist next week. How will this dr diagnose what’s wrong? I’ve gone from dr to dr to dr. I’ve had cancer twice years ago. Am I on the right track by going to endocrinologist? I just want to get better. I’m confined to my bed at age 59 with 8 fractures in my spine that do not heal. I could use some serious feedback. Thanks in advance.
Thanks for the vidéo and the clear explanation.. But can you please explain to me why there is high level of ALP in osteomalacia I really didn't get it.. please?!!
@@MedicosisPerfectionalis ok great that's really do make sense 👌...ah but is't because of hypocalcemia that osteoblasts stimulate osteoclasts by ALP to cut down the bone?!!
I have a question doc. You said in pancreatitis, amylase and lipase will rise. Amylase is not specific ( sensitive ) while lipase is. in acute pancreatitis which enzyme will rise more ? amylase or lipase ? Thank you so much 🙏.
I don’t know...Your doctor is the one to ask, he/she knows your history, physical exam and all of your labs...I wish I could help...Best of luck to you and please keep me updated.
My 20 year old son's ALP is 349 U/L as shown in a recent blood test. In addition, his protein and Vitamin D are very low. The doctor whom I consulted insisted nothing is wrong with his liver. Instead, he said that the elevated ALP is due to low protein in my son's body. So the liver produces more ALP to absorb protein from the food intake. His explanation somewhat confuses. What is your take on this?
@@federicomanzo9858 Sorry, I missed reading your reply. My son suffered a seizure due to Vitamin D deficiency I'm April 2022. He became wheelchair bound. He is undergoing rehabilitation and physiotherapy for recovery.
@@Self_Aware_Since_Aug_29 Please get an immediate blood test of your son's calcium and Vitamin D level. My son suffered a seizure due to Vitamin D deficiency in April. It turned out the high ALP reading was due to acute deficiencies of calcium and Vitamin D.
Sir my alkaline phosphatase is 180 .. I have digestion problem and bone weakness and pain too . Sir please tell me it's is dangerous or not ... what should I do. Please sir tell me I don't want to die 😥😥😥😥
is this your normal voice? kinda liked your voice in previous videos like in anemias and missed your puns in these videos that made your videos more catchy and enjoyable. anyway love your videos.
I just got my blood results back and everything was normal except I have low alkaline phosphatase and low unsaturated iron binding capacity. Does anyone know what this means. They didn't explain it the lab just sends your results to you. I have to pay for a doc consultation
💊🦠 Antibiotics Course: www.medicosisperfectionalis.com/
🧠 Autonomic Pharmacology Course: www.medicosisperfectionalis.com/
Hello
My ALP is 230. How to find a cause?
I've been sharing these videos with everyone in my PA class while we go over hematology. They've been a life-saver. Thanks so much.
Best comment I’ve read today...Thank you so much...Good luck with your exam!
Your channel is the best on RUclips! Thank you so much for helping me understand.
Thanks a lot for your kind words...Your encouragement and support means the world to me...I cannot thank you enough...I would just like to politely request that you share my videos with others...It really helps! Thanks a million!
Your videos are great! I've been struggling to keep these enzymes straight as I study for the Chemistry ASCP exam but these videos are helping a lot. Thank you very much!
My pleasure...Good luck with your exam!
@@MedicosisPerfectionalis I'm interested in bone alkaline phosphatase, which I gather is different to blood Alp. My bone alp is 23 so do you have a video about low bone Alp?
I’m confused because from what I’ve studied so far is alkaline phosphates is an enzyme
Is it biochemistry you study
You make studying a whole new experience for me, all fun and exciting. Thank you! Keep it up!
My pleasure 😇
Can you please help me by sharing?
Nice tip to remember for ever.hepato bilary ,musculoskeletal
Perfect! Thank you!
My pleasure 😇
Thank you sir but you don’t explain the mechanism of high ALP in blood in these disease why alp increases in biliary disease? Is it because of destroying of cell which releases alp in blood or some other mechanism?
Excellent wonderful teaching
Bundle of thanks
Plz keep on doing this charity work
Thank you!
Plz upload more and more videos you are the best !
You made my life esay ❤
I wish you all the best medicosis
You too!
جزاك الله خيرا في الدنيا والآخرة 😊
Thank you so much 😊
Very nicely explained.u have made it very simple to understand.
Thank you so much 😊
Would you please help me by sharing?
How to differentiate if ALP increase because of bone disease or liver disease????
Hi I had a question, if alk phos is low but zinc is good range & copper plasma is on the low side (76 on a scale of 70-175mcg/dl) what could this indicate? Thanks
Why does Alkaline phosphatase inc/dec in relation to PTH? What's the exact mechanism
Nice !!
Why is it normal level in osteoporosis ?
Wow thanks a lot it would've been great if u were my teacher irl 😸
Get my notes 📝: www.medicosisperfectionalis.com/
thanks man
thanks for great explanation
Glad it was helpful!
which app use it to write lecture?🌹
Hey medicosis, I read that ALP is higer in postmenopausal women, could this be a mistake? 3:55
i took zinc 50mg for acne for few weeks, do u think taking zinc without copper cause low alp ?
What a wonderful alkaline phosphatase :3 tks so much ♡ can u explain more details about phosphat fixes ->> phixes ?
My pleasure! Thanks for your kind words! Keep slaying it!
If you pay attention in Biochemistry, you notice that the first step in any carbohydrate metabolism is phosphorylation “e.g. glucose will become glucose-6-phosphate”...Why is that? Because if glucose alone entered the cell, it can diffuse back to the extracellular fluid (which renders catabolism impossible because we can’t pin glucose and fix it inside the cell so that we can perform our chemical reactions on it), so, phosphorylation fixes stuff inside the cell and prevent them from leaving...That’s why my mnemonic is “Phosphorylation Phixes” which means phosphorylation fixes. Hope it helps!
Medicosis Perfectionalis Thanks a lot 👍
My pleasure 😇
@@MedicosisPerfectionalis does ALP increase in fractures? How high it is?
Thanks , it is great
My pleasure 😇
This is great
Awesome 👏
My alkaline phosphate has been over nearly 200 for a year. My bones are extremely thin and fractures are now near 13. This began a few years ago with the fractures when we had mold poisoning from our house. I have an appointment with an Endocrinologist next week. How will this dr diagnose what’s wrong? I’ve gone from dr to dr to dr. I’ve had cancer twice years ago. Am I on the right track by going to endocrinologist? I just want to get better. I’m confined to my bed at age 59 with 8 fractures in my spine that do not heal. I could use some serious feedback. Thanks in advance.
How are you now?
very useful sir
Excellent! Thanks for watching!
Thanks for the vidéo and the clear explanation.. But can you please explain to me why there is high level of ALP in osteomalacia I really didn't get it.. please?!!
Because it starts with osteoblasts that stimulate osteoclast to cut down bone.
@@MedicosisPerfectionalis ok great that's really do make sense 👌...ah but is't because of hypocalcemia that osteoblasts stimulate osteoclasts by ALP to cut down the bone?!!
Yes, and the low calcium is caused by vitamin D deficiency.
@@MedicosisPerfectionalis Understood 👌thank you very very much.. you helped me you saved me.. really thanks a lot to you^^👍👍👍
You’re always welcome...Please share my videos with others... Thanks!
thank you
My pleasure 😇
Amazing
Thanks 🙏
Thanks!
My pleasure 😇
Dr, can you answer this question in detail please? "" is alkaline phosphatase (ALP) specific enzyme for bone disease or not and why?
It’s not specific, because it’s secreted by bone, hepatobiliary system, kidney and placenta.
I have stage 4 sarcoidosis and my alp test results are always extremely high but my doctors have never mentioned concerns should I question them.
Yeah. Ask them what they think.
I am so sorry you’re going through this.
Keep at it!
I came here from MM. Any video explains relation between osteoblasts and ALP?
Yes! RANK and RANK-Ligand ruclips.net/video/6aLAAc9hEzg/видео.html
by the way sir, the outro part i cant hear you speak because the volume is too low.........
Excellent Video!
Thanks a ton!
😅u were coooool and clear
look into hypophosphatasia
Great!
Tomorrow is my examination in med school
I hope I will pass it
How was your exam?
@@MedicosisPerfectionalis
Very good!
I passed it and became a second year med student
The moment i saw 2:45 i paused the video to give it a thumbs up 👍 :)
Thank you 🙏
I have a question doc.
You said in pancreatitis, amylase and lipase will rise. Amylase is not specific ( sensitive ) while lipase is.
in acute pancreatitis which enzyme will rise more ? amylase or lipase ?
Thank you so much 🙏.
Helpful
Thank you 🙏
Hello, my ALP is 98.. what can this be? Thanks
No one can diagnose you based on one lab result.
Please talk to your doctor!
Does low alk phos indicate low zinc?
We can’t jump into conclusion based on this single lab result.
Hello, is 170 ul alkaline phosphatase too bad for a 27 yrs old male? Everything else seems within the range in the comprehensive metabolic panel.
I don’t know...Your doctor is the one to ask, he/she knows your history, physical exam and all of your labs...I wish I could help...Best of luck to you and please keep me updated.
Are you ok? Ever find anything out. I'm at 192 and pretty worried
can you make videos on ecg
That’s a good idea
2:49 Bhagya ❤
My 20 year old son's ALP is 349 U/L as shown in a recent blood test. In addition, his protein and Vitamin D are very low. The doctor whom I consulted insisted nothing is wrong with his liver. Instead, he said that the elevated ALP is due to low protein in my son's body. So the liver produces more ALP to absorb protein from the food intake. His explanation somewhat confuses. What is your take on this?
any update on your sons condition?
@@federicomanzo9858 Sorry, I missed reading your reply. My son suffered a seizure due to Vitamin D deficiency I'm April 2022. He became wheelchair bound. He is undergoing rehabilitation and physiotherapy for recovery.
@@Self_Aware_Since_Aug_29 Please get an immediate blood test of your son's calcium and Vitamin D level. My son suffered a seizure due to Vitamin D deficiency in April. It turned out the high ALP reading was due to acute deficiencies of calcium and Vitamin D.
@@jayac-thind6508really sorry that happened.
Sir my alkaline phosphatase is 180 .. I have digestion problem and bone weakness and pain too . Sir please tell me it's is dangerous or not ... what should I do. Please sir tell me I don't want to die 😥😥😥😥
Talk to your doctor.
We can’t jump into conclusions based on lab result.
Also, no one can diagnose you online.
Don’t give up!
Let’s hope for the best
What is your update? Please get back
What are you doing in Saint Louis? :)
Fun
Thought you live there Im from there :)
is this your normal voice? kinda liked your voice in previous videos like in anemias and missed your puns in these videos
that made your videos more catchy and enjoyable. anyway love your videos.
Thanks for your feedback!
I just got my blood results back and everything was normal except I have low alkaline phosphatase and low unsaturated iron binding capacity. Does anyone know what this means. They didn't explain it the lab just sends your results to you. I have to pay for a doc consultation
my throid levels were normal but can that still mean I have hypothyroidism
Hello Doc my ALP is 158 i workout everyday i lift heavy weights is this concerning? I'm 28years old pls help 🙏🏼
R u ok?
I have 136 alp where 126 is normal.
I have itchy body too
What does it denotes
How about the other lab results?
Can you give me your fb id??
I want to talk
Search Medicosis Perfectionalis on Facebook
I also have itching all over my body my numbers are 132 I won’t know until I get an ultrasound
any update?
Keep it up 🥰🤍
Thank you 😊
I’ve just got my results and they were 150 and then 160 the second time I’m being referred to a specialist. Bit worrried
My alp is a 139
What did they tell you? I got mine this Saturday. And it’s 161
@@imanollaynez2950 it was just vitamin D deficiency xx
@@imanollaynez2950 any update? I'm 192 and very worried.
@@shashamarie4760 vitamin d as well. Mine went down
❤❤❤ amazing which area of the liver that this process happen?
Thank you and proud of you , I think you are Egyptian,right?
❤️
❤❤❤❤❤
:)
Test result showed 345. What does it mean
Update please. I am having issues too
@@shashamarie4760 update please
Naku 617 undi dangerous kada
???
I'm hypothyroidism but with high
Alkaline Phosphate(144).
Please talk to your doctor
innou
Informative but you should stop speaking to people like they are idiots.
Where did that happen in the video?