ALT, AST, ALP & GGT (Liver Function Tests) - How to Interpret
HTML-код
- Опубликовано: 30 сен 2024
- In this TachyTutorial, we explore the basic principles of interpreting Liver Function Tests. We explain what the enzymes ALT, AST, ALP, GGT and what the clinical significance is if their levels are raised. We also explain some special relationships between these enzymes!
Understand and review high yield topics in Medical Sciences and Clinical Medicine. Want to learn something quickly and do not want to waste too much of your precious brain space? Than this is the channel for you.
Made for Students! Subscribe to Learn!
DISCLAIMER: This video is made for educational purposes only and is not made for medical advice. Please consult a doctor or other qualified healthcare professional for medical advice. The information in this video only represents the knowledge of the individual speaking in it and not those of any institution or other individual(s). We are not responsible for any errors or liabilities held within these videos.
#LiverFunctionTests #ALT #HowToInterpret
For me, my higher than normal liver function tests revealed a silent problem that was going on. My ALT and AST started getting out of range growing higher each year (Over a three year period by the lab work results). My ALT hit 153 and AST was 88. ALT by the chart was over 113 past normal and AST was 40 points over. So what was causing my Liver to start hitting the panic button??? Well, an ultrasound of the liver showed the Renal Cell Carcinoma that was growing on my right kidney. MRI showed the tumor growing on my left kidney. From what I have read, the ALT enzyme reacts when the RCC gets into the renal artery. Well, two surgeries later, loss of right kidney and a piece of my left my numbers are back in range. I was in good shape, non-drinker, non-smoker, exercised everyday. If your numbers are getting out of whack and your Dr's tell you to stop eating fast food (That's what the dude told me, turned out to be Cancer) just make sure to keep looking at the problem. My bad Liver Function tests saved my life because I kept trying to find out why it was bad and I indeed found out why.
Did you have any other symptoms?
@@Neenah44 For RCC, not a single one. If I would have just done nothing, I probably would be Stage 3 or 4 by now. My Urologist said that if the tumors would have been reversed, the Ultrasound on my liver would not have seen the tumors and I would not have made 60. I was 46 when we found RCC Stage 2.
@@MrSmith-yr9vk Thank you for answering me I appreciate it very much. I’m happy that you were persistent in finding out why your numbers were growing higher. You literally saved your life. A great lesson on advocating for ourselves! Thanks again. Happy new year! 😊
@@Neenah44 Happy New Year to you and you are very welcome. RCC was not the answer I wanted to hear, but it was the answer to my problem so far.
@@MrSmith-yr9vk bro.... i have ....258.0 - AST,471.9 -ALT,221.9-GGTP,447.00 - ALP ............ i was used to be proper in shape with 83 kg BW...now it turned into 73 in just 2 weeks.... i used to hit gym.... no alcohol ..even not fast food intake.... nd now i fukd upp
Like everyone else here is saying - this is an amazingly digestible breakdown of liver enzyme analysis. I actually feel like I have some rough idea of how to interpret values now. Thank you!
Thank you for watching!
Seems way too dramatic bearing in mind everyone often has raised alt.... with every course of pain killers, pub visit, protein shakes use, junk food lifestyle and many passing infections. None of these raises represent liver damage... so maybe remove the damage and put back the function where it belongs
All I can say is WOW!
I could not understand these enzymes any better.
I like the fact that you started by highlighting where each one of them is found and that made it very easy to Interpret the results.
Im officially your subscriber from now.
Thank you so much for your great feedback! Very useful! Glad you enjoyed and welcome to the channel!
The best video out there on LFTs!! Thank you so much!
Thank You!
True
@@TachyTutorials ,
Right 👍👍
In India, we frequently find ALT values in thousands, 2 to 3 thousand , in case of Viral hepatitis
Yes absolutely.. Patients need not worry as Hepatitis can cause ALT level as high as 10000 (as in my case). So be relaxed and get admitted under medical supervision immediately and you will be fine within weeks or maybe months..
Excellent. Was diagnosed with autoimmune hepatitis and treated most of last year. Turned out to be an infected gall bladder.
how u going now bro?
@@jjohnson9822 good, except being 85. The body is worn out from overuse :)
Good evening sir, were is treatment autoimmune hepatitis primary bailary colanjaitis.
Hello Mr Stanley Cates. Did you have to take prednisone or azathioprine? Asking because I had the same diagnosis and my gallbladder removed.
Can anyone plzz explain me the difference between liver infection and liver damage???
I suggest you look into anti dressants. I have MTHFR c677t. My liver detoxes 70% slower. I allowed myself to be put on an anti present well butrin an enzyme I a had under control rose.
What was high? I have ALP moderately high, GGT normal and. mTHFR mutation . Thanks!
Amazing doctor! Thank you for the interpretation! 🙏👍
what about NAFLÐ (non alcool fatty liver disease)?
Exactly this video is dumb trying to scare people
Total bilerubin 0.9 direct bilerubin 0.3 indirect bilirubin 0.6 sgpt70 sgot 37 ALP136 total proteins7.4 albumin 4.2 globulin3.2 all are normal sgpt is little hig any problem I'm facing fatty liver problem non alcoholic I'm using medicines T URSOTOR 300 DAILY MORNING AND EVENING LAST ONE MONTH and obenow 10 mg and tocofil afternoon after the lunch
Hight GGT only is : Auto brewery syndrome is also known as gut fermentation syndrome and endogenous ethanol fermentation. It's sometimes called “drunkenness disease.” This rare condition makes you intoxicated - drunk - without drinking alcohol. This happens when your body turns sugary and starchy foods (carbohydrates) into alcohol.
What if you don't drink and no it's not
This is awesome. I have actually learnt alot from watching this and am glad I found your channel. Please can you give us tutorials on lipids profile as well
Your interpretation is amazing, i ws able to grasp it easily. Thank you so much, God bless you. Hadiza from Nigeria.
Thank you for your support!
No one can do better explanation than this. i really find value
Thank you!
What does it mean if there is no liver damage? Does it mean that it is functioning well?
Amazing video, thank you! if GGT, is raised and ALP is normal, accompanied by elevated AST and ALT (AST higher than ALT, but both raised), what is the likely outcome for that?
Alcoholism 🔥
@@drendolob what if you do not drink?
How’s your liver doing now?
Yes ,u also want to ask , same reports,,can't interpret
@DL 0001
Could raised ALT and AST be due to beta blockers and/or anti-coagulants?
Good explanation, animations superb.
Thank You!
Mine was due to alpha1antitrypsin deficiency! I think everyone with the high levels should be checked for this today! It’s not an expensive test and needs an early diagnosis when possible🙏
thank you so much for this video and the important information included herein.. had lab tests done and both alt were aboeve normal, the 2nd result was even higher than the 1st and ast also was above normal but abdominal ultrasound shows normal liver impression..
What an awesome journey it has been. Coming across Dr Igudia RUclips channel has been a testimony. Finally got rid of Hepatitis B Virus. Thank for your service and dedication, you are a blessing to us Dr Igudia, Gratitude
I have hep c(30 years now) and cirrhosis of the liver(13 years, possibly longer) I don't drink alcohol and I got hep c in the 1980s in Thailand when I got a tattoo. My GGT is roughly 80 and every other test is normal.. They tell me, the hospital.. I have chronic pancreatitis.. Low white count and neutrophils occasionally.. A hernia by my liver, I have the double duct sign as my cbd and pancreatic duct are always dilated, cbd about 10mm and pancreatic duct 6mm,they don't know why and refuse to look, I have a gallstone they refuse to remove and I have a splenic artery aneurysm with diverticulois and now I have stercoral colitis, the drs ignore this where a medication they are giving me causes me terrible constipation and terrible pain and I can't eat any meals.. I just got a phone call off the A and E the other nigt saying I had candid is after a vaginal swab but I don't have any symptoms in my vagina but I have the white discharge in my bowel, and they couldn't do a colonoscopy because the prep won't work and laxatives no longer work because since starting this horrible medication I have severe constipation and I also have QTc prolongation from the same medication.. I'm in terrible pain all the time but get told my bloods are normal but I never see them often my stomach swells out and all I eat are chocolate smarties for a year, nothing else... I'm terrified of this all, I have no dr or GP and also I have emphasemia... Please can anyone help me with any advice as I'm very worried as Drs get sick of me going to hospital for 😣 where they say I have constipation and nothing works to relieve me and stercoral colitis is rare but dangerous, when not watched.. I'm so scared.. Any one, please help I'm in New Zealand and the hospital where I live has a terrible name for alot I hear, and I'm not surprused😢
Can't help you really, it's sounds like you need to get a second opion at different hospital. But you know that hep c is curable with medication?
What could a high AST:ALT ratio (>2) with low to normal GGT suggest?
That truly was the best and most informative, easy to understand explanation ever. Thank you!
Thank you for watching! 🙂
Excellent presentation! Thank you very much!
Appreciate the comments. Thank you very much
This is the best explanation ever…..
ihave an Isolated high GGT all others are normal, and im not an alcohol drinker, What could this isolated ggt mean?
I have the same, and it accompanies hepatobiliary problems. I have read, it can be indicative of inflammation of the bile ducts.
White Thomas Gonzalez Edward Hernandez Helen
Thank you... you saved many hours of my study time 🥰❤️
Glad you found it useful 😊
Perez Jason Anderson Joseph Williams Jennifer
My alt is 20 and my ast is 20. This is the second time they have been the same. Is the ratio important to look at? My ALP is within normal limits and my doctor didn't comment on it so I don't know if I should bring it up. I have been diagnosed with fatty liver in the past with NASH 1 but I lost about 50 lbs since then but gaining 15 back. My last CT Scan did not show fatty liver so I am just concerned about the ratio since my 15 lb gain.
Did you get the answer for your concern?..I also want to know whether the ratio is important or the values of AST and ALT are important.
Thank you so much.... Best I have ever seen.
Wow! Thanks so much 🙂
Thank you for this video.. God bless 🙏
Thanks for watching 🙂
If my ggt is at 5 what does that mean??? Our scale here in Denmark says it should be between 15 and 115. Help!?? 😁💪🇩🇰😉
Should be between 30-35
Wishing you had included a low ALP result. Otherwise, great information.
Thank you so much for the clear explanation!
Glad you found it useful 😊
15576 Patrick Light
My heart just keeps thanking you and thanking you Dr Igudia for all you have done for me, you gave me your words that you could heal any sickness or disease, thank you for permanently curing me of my Hepatitis B disease you are amazing
disappointing. And due to the low probability of the explained conditions, irrelevant.
Why not showing the all cause mortaity curves for ALT + AST ? why then not discussing values >40 and < 200 for either of those? tat would be relevant, because 30%+ of the population is affected.
Tacky tutorials Can the DTaP shot raise AST if given directly before blood work?
Excellent presentation to Doctors and Patients
Starting at 7:34... This is inaccurate. ALT is more specific and is usually elevated above AST in alcoholic liver damage.
Upon getting my Bloom simple tests results.....de hace discovered i am experiencing "LowLevels of GamaGlutamylTransferase" I am uncertain what that implies....i do know i am experiencing VeryLowEnergyLevels????
Normal AST &ALT but alightly high GGT ( results 43 &51) can chemo do this?
my blood tests came back and everything was good except my ALP was very low - what does this mean? The lab did not explain anything. Can this be the reason for Rosacea and/or weight gain?
My AST and ALT were normal
Doc my ast is 21.3 and my alt is 26.5 which the ratio is .80 that is less than 2, but my upper right abdomen is painful and the right side of my ribs, what is that doc? Could you enlightened me for that situation
I am 25 yrs old and my ALT came out 157.9 and AST at 78.7. WTF, can this still be lowered? It is 3x and 2x of the normal levels
I’m sorry but I think you’re forgetting something pretty important. ALKP also elevates with inflammatory conditions like IBD
Well explained to my understanding. Thank you very much
Alt 40. AST 30. Alp 47. Ggt 85u/l.
Have not drank alcohol for 5 years. What’s up with ggt being 20 points out of range?
What if I only have elevated GGT but I don’t drink alcohol?
I was diagnosed with fatty liver but my doctor said it is unnecessary for me to have a GGT test performed. Is this true?
The doctor told me my ggt level is slightly mildly raised im worried and dont understand this can you guide me more is this life threatening
ALP elevated by osteoblasts,so bone disease perhaps but technically does not need bone destruction, so can differentiate early versus late Pagets on test questions
Sheridan Islands
ALt 180
Ast 68
What to treat for it??? Plz give me advice and tell me is it normal
What if the ALP is LOW ?
great explanation, thank you very much
Your welcome 🤗
In this year I study liver function test from your channel I get It thanks alot
My ALT and ALP is mild raised after my C section surgery. What could be the cause
did you find out the cause?
@@RAWRitzLiZzi dehydration may be and alot of antibiotics and painkillers use after surgery
Excellent explanation.
😀😀😀
Harvey Flats
Kelvin Ways
Mariah Lodge
AST alt also in the muscle found so it’s false reding only good one is ggt on liver
Weimann Glens
Carter Meadow
Murray Branch
Amazing explanation!
🙂🙂🙂
Shanahan Square
Genius. amazing explanations
Thank You!
My test include AGPT and SGOT not sure what it means.
That was really beneficial 🤌🏼
My ast 52.8 and alt 86.1....sap 103 pl suggest it's ok
Freeda Grove
Excellent explanation. Thank you.
Thank you for watching!!!
Hello, my GGT numbers are coming out to 111 other than that everything else is good. I have over a year and a half with out drinking alcohol just recently i had 1 drink thats it. What are the factors that could be causing my numbers to continue to increase? And is it reversable? If so how can I drop the numbers?
My ggt level went to 166 and i dont know what to do? Any suggestuons ?
@@pavanpabbireddypavanpabbir1897 ...suggest low carb/keto diet
sugar causes high GGT, as I understand it
Tina Parkway
So with a small raise in GGT on blood test but all others are fine is most likely cause I drank a shit ton of alcohol 4 days before during a crazy weekend?
Kreiger Dale
What about Liver Steatosis? NAFLD?
Wow thank u for this eloquency 👏🏻👏🏻👏🏻
Thanks for watching 🙂
Dominique Prairie
Thanks
Wonderful explanation. Keep sharing more
Thank you for your support!
It was more than awesome! Keep up!
Thank you! Glad you enjoyed 🙂
Sir mera Alt sgft 129.2 U/l uotp 42.0 u/l
Great lecture.
🙂
Great analysis but i suggest you to use better microphone for sound quality
Can elevated diabetes numbers cause elevated elevated liver enzymes
Awesome video! New sub man
Thank you so much!
Well explained
Thank you! 🙂
Thank you l understand it better now
GGT WAS 1048 WHAT DOES THAT MEAN THE OTHERSWERE OK
I had fever vomiting for a week then had my ultrasound and blood work done in the 11th day of my first symptoms
My blood test showed multiple times higher liver enzymes alt was the highest tho.
I started developing jaundice at the 10th day.
I had my ct and another ultrasound by the end of the second week but it was all good except for a few lymphnodes enlarged next to the gallbladder.
On the 19th day i had a new blood work and it showes all enzymes decreased drastically and it is not too far from highs normal levels. Thats being said bilirubin kept increasing and hit 125 umol/l while it was 77 in the first blood work.
I am feeling much better but still cant eat normally because i get uncomfortable feelings in my guts
Any ideas?
It sounds like a bile duct blockage perhaps? Blocked by sludge. The bible ducts release bile that aids in helping to break down the food we eat so the stomach can digest it. If there's a slow down in bile production, then it effects how we digest food and can cause stomach pain, but if it's mainly the Alt that's elevated, it can often point to liver and the Ast can be liver but very high can point to the billery system. I'm not a doctor, but since I have chronic liver disease, I would naturally do the research. Your P.C.P should get you set up with a G.I./ heptology Doctor. It's not like you will get any answers on these sites from an actual Dr. As they hate to give info without running their exams on the patient first, and perhaps to even get in trouble hand out info. But again you should see a specialist being a G.I. / heptology, I would!! Good luck.🙏
Great vid
Thanks!
Thanks for watching 🙂
I am not a drinker or take medications. I am not over weight, in fact, i have lost 40 lbs. and very weak and tired. I was in the hospital this week and my liver enzymes were ALT 444 and AST 554. My hepatitis tests were negative. What can cause these very high readings? Thank you
Hello Kevin did you ever find out why your AST were high I just did blood work mine ast is 151 , what cause that any treatment for that ?thank you
I am scheduled for an MRCP next week to try and find out. The Dr. Said he hasn't ever seen someone's readings were so high without an obvious cause. Could be autoimmune hepatitus or a tumor or cancer or blocked bile duct or spincter of oddi.
Liver is amazing it’s one of only organs that heals itself however it takes very long time my ALT Levels took 6 months to reflect my new healthy body and lifestyle
Hey Kevin do you have any symptoms I was admitted to the hospital 2 weeks ago. Because alt 760 and ast 730 I had fever stomach pain and I've been having shortness of breath
@@adrianarivas5648 I had all those except fever. They never figured out why my readings were so high. Mine came back down.
Wow , Awesome thank you Doctor
What if both alt and ggt raised.?