Liver Function Tests (LFTs) | Clinical Medicine

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Ninja Nerds!
In this lecture, Professor Zach Murphy will present on Liver Function Tests (LFTs). We will discuss the components of LFTs, including tests for enzymes like AST and ALT, bilirubin levels, and protein synthesis markers such as albumin and prothrombin time, and what they reveal about liver health. The session will transition to a digital presentation focused on the interpretation of these tests, identifying patterns of liver injury, and distinguishing between hepatocellular damage, cholestasis, and liver synthetic dysfunction. Finally, we will review how LFTs guide the diagnostic process for liver diseases, from viral hepatitis to cirrhosis and hepatocellular carcinoma. Enjoy the lecture and support us below!
Table of Contents:
0:00 Lab
0:07 Liver Function Tests (LFTs) Introduction
0:56 Tests for Hepatobiliary Injury
13:10 Tests for Hepatic Function
21:21 Hepatocellular Injury
36:46 Diagnostic Approach to Hepatocellular Injury
40:23 Cholestasis
51:03 Diagnostic Approach to Cholestasis
54:02 Hyperbilirubinemia
1:18:54 Diagnostic Approach to Hyperbilirubinemia
1:22:01 Comment, Like, SUBSCRIBE!
Retired Ninja Nerd Lectures:
• Liver Function Tests (...
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#ninjanerd #gastrointestinal #liverfunctiontests

[@dom6783]

After years of not understanding this topic... I finally understood it. Completely blown away. Thanks so much Zach. The video notes were Amazing to go along with this video.

[@KM-vc7iy]

I am assuming you are studying to become a doctor. Just want to ask if Conj Bilirubin shows +1 of upper limit of normal (Total Bilirubin normal) and GGT is normal but ALP shows a high abnormal number though

[@esraawaliiid68]

Please can you make videos about Cardiac Function Tests & Kidney Function Tests,too 🥹🥹 we all need such a great teaching in these 2 complicated topics🥹🥹🥹

[@clairefisher13]

Omg yes I would love the kidney function one

[@CarolReidCA]

He has them. Search the channel.

[@bukurunestory3540]

Excellent Presentation skills, you make my life in Clinical medicine real easy.
Thank you Prod Zacky

[@erikadossantos8248]

I love this videos they are so informative and very visual so everyone can see and understand it easily. Thanks for making this possible for us.

[@i27-jrboy]

من الجميل ان تدخل الى مقطع فديو لشخص ينقل المعرفه لاناس لا يعرفهم ولكن الاجمل هو ان المقطع برمته لا يشاهده سوى الاطباء بإستثنائي كوني طالب مرحلة اعداديه ولكن على كل حال هذا هو حلمي أو لكي اكون اكثر دقه مستقبلي ان شاء الله❤

[@fawaz0779]

كفوووو

[@jaffarhaddad4128]

لا تتورط اخي

[@i27-jrboy]

@@jaffarhaddad4128 احلى ورطه

[@user-my5pw6qu9x]

This is very helpful, thank u so much

[@habibyounes8711]

Much love ❤️... thank you for making medicine easier to understand properly

[@brofred7623]

Just awesome. Thank you Zach ❤

[@evelineache7718]

thank you so much for what you do. I'm learning a lot from you. I'm a practicing general practitioner

[@dominickimathimugambi5332]

great lesson. Asante Sana (Thank you very much)

[@sonamdhondup5426]

wonderful video. thank you!!

[@artemgoatlobov1722]

Zach looking jacked lately

[@vincentcyrilliansantoso9858]

Thank you from Indonesia!

[@dishapranami8092]

You are saviour man!!!!❤❤❤

[@aravindnarayan7402]

Thank you

[@sandra25]

tysm, helped a LOT

[@drrahulnandi]

Thank Your Professor Zach Murphy! Love♥

[@niloofarghorbani7424]

Thank you!

[@anbu.s]

This is Anbu from Tamilnadu (India) after long time waiting for new videos

[@maritabrown1343]

very helpful video

[@arwaarwa1840]

Piece of cake
Thanks to you 😊

[@bells7235]

Thank you!!

[@JN-kk4nk]

Thanks team Ninja !!

[@shareenobles9978]

So helpful

[@bipintiwari6249]

Thank You !

[@Hhhghgt]

Superb 👍

[@drriturajmukesh2058]

Thanku so sir

[@aammiirramir1183]

Thanks ❤

[@doctord2826]

Thank u sir❤

[@Handle_symphony]

Ty

[@user-nh1md5ws1b]

You are special ❤

[@ashwaqal_tai3777]

A greatness ❤

[@alaa53ali]

ما أروعك عمي نينجا 🥷 ♥️

[@i27-jrboy]

😂😂😂

[@i27-jrboy]

تخيلي اني طالب سادس وجاي اخذ بريك بمحاضراته

[@ashwaqal_tai3777]

Thanks from iraq ❤

[@iliyaghiyasvand]

we pay you back someday Zach❤

[@madisynwright]

Wouldn't low albumin levels causing pressure changes, capillary leakage, and subsequent edema be a transudative process and not an exudative process?

[@CarolReidCA]

It can. If it isn't controlled and becomes systemic, multi system organ failure and compartment syndrome can follow (SCLS aka Systemic Capillary Leaking Syndrome or Clarkson's disease (when chronic). Ascites will be present if this occurs. Every patient is different.
Note that some patients will never get jaundiced, will never have upper right abdominal pain, but they'll seem like they have a very bad stomach flu with Vomiting, and within a few hours, or if not caught, minutes, they can turn blue on you very fast.
Check the urine, stools, and labs.
They may come in with some difficulty breathing, some vomiting, and "don't feel right," which can be from ammonia.
You can't ignore patients who have chronic liver failure or it will lead to acute liver failure (ALF), and if not properly addressed, they can die rather quickly.

[@user-op5cw6hg1l]

Dear Amazing Friend, More clinical videos please

[@mimimimona4149]

Thank u❤❤🎩

[@Motivationtosuccess-qs7ih]

We need a kidney function and cardiac function test too 😢,please.

[@phamdung3884]

33:40 Calling autoimmune “lucky” made me giggle a bit. I understand though. 😂

[@beastmode7107]

nice

[@camilasalcedo9469]

NINJA DADDY te amo

[@sanjith1179]

I'm pratheesh from india (tamilnadu).big fan of you sir.say one hii sir.

[@nakitagovender4283]

Please can you do a video on fluid administration under clinical medicine? The different IVS, eg dextrose, HCO3, saline etc and how they affect Tonicity and what’s for replacement or management 🙏🏽🙏🏽🙏🏽

[@07-benniesalona15]

There is a nice one on Intellect Medicos channel, and on ICU advantage YT channedl :)

[@beastmode7107]

I LOVE your Shirt!!!! SCHRUTE FARMS

[@majidghani5416]

❤❤❤

[@ivettj.heredia8974]

♥

[@ridhakareem2709]

❤❤

[@dummysalami]

Are you reuploading? What is going on

[@sarahahmad4147]

❤❤❤❤

[@abrahmbore9328]

What actually causes the elevation of AFD up to 8890?

[@marcellachmely5206]

watching his tattoos grow

[@moonphetamines]

Shouldn’t it be AST > ALT in NAFLD (39:24)

[@KM-vc7iy]

I am assuming you are studying to become a doctor. Just want to ask if Conj Bilirubin shows +1 of upper limit of normal and GGT is normal but ALP shows a high abnormal number though

[@moonphetamines]

@@KM-vc7iy Are you a male/female, how old are you, what is your BMI, for how long have you been experiencing RUQ pain, can you express your pain in details? (When do you have a pain, does it happen right after eating something especially rich in fat, how much would you give it out of 10 -10 is the strongest pain- how long does it last once it happens, does it wake you up while you’re asleep at night, do you have any other symptoms other than pain, when does the pain go away -like after eating certain foods or having medications-) Do you have any co-morbidities, do you have any liver-gallbladder related diseases in your family? (Or any chronic illnesses that you know?) Are you currently on any kind of medication? (like OCP) Have you ever been pregnant, if you’re a female? I can’t say much from here but I can still try to help you if you express yourself more clearly

[@chaimaa4303]

grenat

[@aravindnarayan7402]

Urobilinogen is actually colourless. Urochrome gives urine its yellow colour.

[@williambennett7935]

Please stop putting the caps back on your markers while recording. I’ll buy you new markers if they dry out.

[@stxx.6441]

Thank you

[@sarahahmad4147]

❤❤❤

[@leonchikumba]

Thank you