BLOSUM matrix

This video contains an overview about BLOSUM matrix and how to construct a BLOSUM matrix for calculating the score of the sequence alignment when we study sequence comparisons. BLOSUM matrix is commonly used matrix (like PAM matrix) in the field of bioinformatics mainly in sequence analysis. BLOSUM matrix was first developed by Dayhoff and Dayhoff. Default matrix for protein blast is BLOSUM 62. BLOSUM matrix are mainly used in protein blast where local alignment is performed.
You can check other videos, link is provided below:
PAM matrix
• PAM matrix
Scoring matrices: Basic concept of scoring matrix
• Scoring Matrices: Basi...
Global Sequence Alignment (Needleman-Wunsch)
• Global Sequence Alignm...
Sequence similarity and identity
• Sequence similarity an...
The concepts of Homology
• The concepts of Homolo...
Sequence Comparison
• Sequence Comparison

[@sudhavani4306]

Thank u so much for biologist is very good explanation

[@nikhithamanne2144]

Worst explanation I've ever gone through

[@sudhavani4306]

If u can do a better explanation pl. go a head and make a vedios

[@redDL89]

3:11 - 3:32 Why is it that the two A's in the first column means A can be substituted only one time, but the five A's in the second column means A can be substituted 10 times? How does that work?

[@bsanzana]

5! / 2! (5-2)!

[@trannguyenanhthu7607]

@@bsanzana hi, can you explain for me the formulation to calculated some of the number in this table form 3:11 - 3: 32, pls. I don't know how it come to, thank you so much

[@Luffy_D_1999]

Very helpful 🥰keep going di and bhai..

[@BioinformaticaYT]

Thank you so much Shubhankar

[@BineetX]

Really helpful, thanks alot 😁

[@nidhikumari9126]

Thank you🤩

[@bennaceursirine4459]

hi can you please send me the voice explanation? thank you in advance

[@ashutoshbhardwaj1025]

👏

[@PayalKumari-fx9zl]

👍👏

[@vaibhavadicherla5145]

Needed some better explanation

[@LocNguyenTien-yh4hp]

wtf is cij,bro dont even give the equation ?