Dr. Marom Bikson: The potential and Limitations of Transcranial Direct Current Stimulation

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  • Опубликовано: 21 май 2024
  • Presented during the Society of Biological Psychiatry 73rd Annual Meeting in New York on Saturday, May 12, 2018.

Комментарии • 20

  • @Texmatt21
    @Texmatt21 2 года назад +6

    I've noticed a vast improvement in my mental well-being with tdcs, particularly when combined with mindfulness meditation. Now I know why. I highly recommend tdcs for those who are suffering from depression. The literature supports its efficacy in many other areas, but it absolutely worked for my depression.

    • @craigm5713
      @craigm5713 Год назад +2

      What montages or pad positions did u use?

    • @Karla-mu6hn
      @Karla-mu6hn Год назад +2

      So wonderful for you. Which device did you use?

    • @shenraine
      @shenraine Год назад +2

      Which device did you use?

  • @mohammadmasoumi272
    @mohammadmasoumi272 3 года назад +1

    How could be joint or participate in the study, e.g. materials science and engineering?

  • @user-gq5ee5vr7y
    @user-gq5ee5vr7y 3 месяца назад

    Has anyone got M.E. and used the device? Any probs/higher sensation on forehead?

    • @UsandEveryoneWeKnow
      @UsandEveryoneWeKnow 3 месяца назад

      I am always exhausted but it's been put down to depression, it's helped a bit with sleep quality. Also get dermatitis on my face at times and where the electrodes go it has flared it up, but seems to be easing as I get used to it. No sensitivity after using, only during (a stinging/ burning feeling).

  • @MerlinSingh
    @MerlinSingh 4 месяца назад

    What do people here think about Flow? It’s possible to buy now. But quite pricy for the regular person

    • @UsandEveryoneWeKnow
      @UsandEveryoneWeKnow 3 месяца назад

      I'm using it, there's a 30 day money back. I think you can rent for 3 months then buy at a discount, so it works out about the same price in the end, factoring in the pads they send with rental.
      I've had depression that's spanned decades, quite debilitating I'd say, been on every medication going (lots of antidepressants and also anti-convulsants) some quite nasty.
      I wasn't expecting to feel anything with flow but it actually made me feel a little stoned/sleepy. I struggled to do it on the days you are meant to, but have been forcing myself. The process can be annoying, but staying with it. I suffered deeply with my sleep and that caused more depression and exhaustion, so it helping me sleep a bit has been of some relief. I do feel a bit funny for a bit after using it, foggy, but think that's easing with use, and I like to do it just before bed (phone on night setting, so no blue light when using the app) to aid sleep. Still struggling and have days when I've felt crappy, but do think it's somewhat helping me and taking the edge off, which I'll take. Feeling a bit better hasn't necessarily translated into doing more, or getting things done that I need to, just more of a sense of calm. I've noticed for example if something happens that really upsets me and I cry, I can tell I'm upset, and know I'm crying, but don't feel the tense pain in my head that I'd normally get along with that, so slightly numbing. Still only on week 3, so not sure if there will be any further benefit. I know from reading some people don't get a benefit until week 4. And reviews are 50/50, some get nothing, whereas others who have been in very dire straits have had their lives transformed. I'm definitely a tough case, won't go into it, but relatively pleased with even just help with sleep. There is a Facebook group where you can read other people's experiences, good and bad and get a range of people's feelings on it.

    • @UsandEveryoneWeKnow
      @UsandEveryoneWeKnow 3 месяца назад

      Apologies for just repeatedly adding my postal tracking number for an item! 😂 My phone's playing up, froze and just repeatedly added it as a reply as I hacked at the touchscreen.

  • @healingvalleyphysiotherapy8268
    @healingvalleyphysiotherapy8268 3 года назад

    👍

  • @calcal5135
    @calcal5135 4 года назад +5

    Did a single audience member question this erroneous use of the reciprocity theorem or this speaker’s misunderstanding of the EEG inverse problem? Sure would have been a nice talk IF IT WASN’T WRONG.

  • @calcal5135
    @calcal5135 4 года назад +8

    If you understood the basics of the ill-posed inverse problem of EEG you wouldn’t be making your BS claim that one can stimulate the EEG source by reciprocity.

    • @farcenter
      @farcenter 2 года назад +1

      I'm happy I'm not the only one who thought that seemed like a wild claim. How would someone even defend that claim? it doesn't make any sense. even if the the "inverse" of an EEG could cause depolarization, how could it find its what back to a point of origin, let alone preferenchly interact with specific neurotransmitters? Am I missing something? is this a main stream view in this literature? ah. sorry for the rant. is there's any legitimate literature on this, if so would love to hear of it! Cheers

    • @calcal5135
      @calcal5135 2 года назад

      @@farcenter
      You don’t have to go there (neuro transmitters etc). He simply misunderstands the reciprocity theorem and his claim about producing the same current density by tES as that which served as the source for the EEG electric field is just wrong wrong wrong. I never have liked the reciprocity theorem because it is misapplied so frequently. Regardless, the non uniqueness of the EEG inverse problem, which anyone in the field should be aware of, should have stopped him from making this wild claim. It appears he continues to do so albeit with not-so-clever rewording of his original claim.
      It took me all of 2 minutes to shoot down his wild claim when this work first appeared and so many thought it was so clever. It is appalling that reviewers, who would have spent hours reading and critiquing his work, missed the obvious. Peer review is a pile of dung.

    • @ShivaTD420
      @ShivaTD420 Год назад +1

      The signal travels through neurons that are already in action potential. Much like how electrons conduct through an arc, the ion channel depolarization forms a path of least resistance.
      The neurons ion channels activate in pulses, which cause oscillations. These waves are important as phase array based stimulation allows the equipment to create standing waves which are either in phase (amplification) or out of phase (interference).
      The depolarization of brain cells forms dipoles. The inverse problem was solved by bidomain and monodomain inverse operations in 2015.

    • @Tommy-lq2rk
      @Tommy-lq2rk 9 месяцев назад

      ​@ShivaTD420 is there a Source for this? How can this even be allowed and marketed in the way it is. This is nothing other than strong magnetic fields aka brainsmog. And a lot of it which is really harmful

    • @ShivaTD420
      @ShivaTD420 9 месяцев назад

      @@Tommy-lq2rk well the research probably began as far back as electro shock therapy. Running a alternating electric current through the brain severed connections, this effect was done in hopes that bad connections that may be the source of the person's problems would be destroyed giving them some relief. This process was largely reserved for rare cases and the effects were somewhat unpredictable. Had lots of bad effects like memory and skill loss, personality changes , triggering catatonic states, seizures, comas.
      The second breakthrough was using DC current, but it was found that this couldn't penetrate into the brain very well, with most of the current flowing across the skin to the other electrode.
      As eeg technology improved brain mapping improved with it. Areas of the brain were charted. The third breakthrough was sampling different brain states by having the patient think about different things, stimulus and lack of stimulus and performing actions. Parts of the brain generate different signals during these tasks and these signals are recorded.
      The magnets and phased arrays would be the fourth breakthrough where it was found that the magnets allowed the DC signal to reach into the brain. Here it was found that brain cells in action potential formed a conductive path for the DC signal to travel down. Using phased arrays helped get a standing wave deeper into the brain. The recorded signals are usually used , so the brain is just getting samples of your own activity into areas of interest.
      The most recent breakthrough is that of using the optic nerve to reach deeper into the brain, accomplishing a deep brain stimulation effect similar to the implanted probes used to treat Parkinson's.
      This is all still heavily experimental research, there are only a handful of papers. While the field shows great promise I'm not sure how ones are marketing much claims to a end user aside from a possibility of relief with little known downsides, but this video is largely intended towards researchers, investors and entrepreneurs looking to buy into the technology.
      Magnetic fields by themselves shouldn't cause any issues. The magnetic fields in MRI scanners have Tesla values much higher than one would normally be exposed to throughout their lives, where brain activity is untouched.
      As for the DC currents, there could be risks but for now the therapeutic benefits seem to outweigh any risks. Very little data on adverse effects I have yet to witness any aside from temporary phosphines (geometric patterns in the vision similar to the optical effects seen when you close your eyes and press on them) when the rear of the brain is stimulated.
      I started in the field when this process was used mainly on people recovering from traumatic brain injuries and to halt seizures. But it has since expanded into other areas of mental illness. Some of these people have tried everything else and are desperate for some sort of relief even if it is placebo. While I wouldn't make any promises I can say it's largely low risk, low invasiveness and somewhat cheap vs things like surgical procedures or a lifetime on various medications that are almost as misunderstood as the diseases they treat, while they alter brain chemistry and the patient barrels towards tolerance of the compounds which result in higher doses or changing to other compounds with different modes of action, to keep up with the therapeutic benefits, but increasing the prevalence of unwanted side effects.
      We all have theories on how we think it works, but we are lacking on hard evidence somewhat related to the fact that some of the mechanics of how certain mental illnesses manifest are also largely not fully understood. Not sure if I can post links without this comment getting deleted but I'll direct you to some of the papers that demonstrate the action potentials becoming conductive paths with magnets helping guide phased array DC signals deeper into brain tissue, or the newer materials on the use of the optic nerve to attain a deep brain stimulation which seems to help Parkinson's.
      I will say I was highly skeptical of the tech initially, since I seen the effects that electroshock therapy had. My critical thinking had me cornered between how could such a low power DC signal make it into the brain at all as it would just travel across the skin to the other electrode rather then through the brain tissue, to if electrical current was strong enough to flow through the brain tissue it would cause damage like electro shock therapy did since you would need such a high current to overcome all the resistance of the body's structures.

  • @rlanetta9767
    @rlanetta9767 Год назад +2

    And oh the possibilities in the hands of evil ones. You take responsibility for your actions . Can you say crimes against humanity in the United States? One of my fav pastime quotes, it's not me, it's the rest of the world that's fucked up. Piece of mind I assure you. It's not love.

    • @Tommy-lq2rk
      @Tommy-lq2rk 9 месяцев назад

      For real they might hurt and destroy a whole lot of people lives and not take responsibility for it. This is basically strong brainsmog which can trigger a whole lot of brain problems and autoimmune diseases. I used this for 1 month but never again. I regret it a lot. This is dangerous stuff