There are organisms which can regenerate almost any type of damage. Zebrafish can regenerate a pin sized hole in the brain naturally. Knewts have been shown to recover from full arm amputation. The major question though is how do they do this. Surprisingly mammals, including humans have the ability to regenerate. Organs like the skin and liver prove as such. For the longest time though, it was believed the nervous system not so much. However research in mouse retina had shown that by preventing scar tissue formation following damage, retinal stem cells (Muller glia) were able differentiate and proliferate very similar to our zebrafish counterparts. While not in the brain, these retinal studies do point at the possibility that brain regeneration is possible. How this correlates to memory retention, that is still a black box.
Is it possible to replace dead neurons that died through neuronal cell death or exicotoxicity.Zebrafish and knewts both naturally regenerate neurons in the brain. The biggest question in the regeneration field is how do they do this (Gene's involved, time line of events, etc.) It is known that ascl1a, stat pathway, wnt pathway, and notch are major players in the regeneration process. A lot of research in the retina by Wyde has pulled out a rather complex gene map. Even with this though there is still a lot that isnt understood as what are the key transcription factors which make the specific type of neurons. As for the question asked above, there is high hopes in finding compounds or cocktails of drug compounds which could begin the neurogenesis process. If scientists could prevent the faster scar formation process from occurring and somehow promote dedifferentiation of potential stem cells, it's possible regeneration would just naturally occur in the brain. (Again this is mostly coming from the retinal regeneration studies)
I know im asking the wrong place but does anyone know of a way to get back into an Instagram account..? I was stupid lost my account password. I appreciate any tricks you can offer me.
@Emmitt Sutton i really appreciate your reply. I got to the site thru google and Im trying it out atm. Takes a while so I will reply here later when my account password hopefully is recovered.
There are organisms which can regenerate almost any type of damage. Zebrafish can regenerate a pin sized hole in the brain naturally. Knewts have been shown to recover from full arm amputation.
The major question though is how do they do this. Surprisingly mammals, including humans have the ability to regenerate. Organs like the skin and liver prove as such. For the longest time though, it was believed the nervous system not so much. However research in mouse retina had shown that by preventing scar tissue formation following damage, retinal stem cells (Muller glia) were able differentiate and proliferate very similar to our zebrafish counterparts.
While not in the brain, these retinal studies do point at the possibility that brain regeneration is possible. How this correlates to memory retention, that is still a black box.
Is it possible to replace dead neurons that died through neuronal cell death or exicotoxicity.Zebrafish and knewts both naturally regenerate neurons in the brain. The biggest question in the regeneration field is how do they do this (Gene's involved, time line of events, etc.)
It is known that ascl1a, stat pathway, wnt pathway, and notch are major players in the regeneration process. A lot of research in the retina by Wyde has pulled out a rather complex gene map. Even with this though there is still a lot that isnt understood as what are the key transcription factors which make the specific type of neurons.
As for the question asked above, there is high hopes in finding compounds or cocktails of drug compounds which could begin the neurogenesis process. If scientists could prevent the faster scar formation process from occurring and somehow promote dedifferentiation of potential stem cells, it's possible regeneration would just naturally occur in the brain. (Again this is mostly coming from the retinal regeneration studies)
I know im asking the wrong place but does anyone know of a way to get back into an Instagram account..?
I was stupid lost my account password. I appreciate any tricks you can offer me.
@Stetson Dayton Instablaster :)
@Emmitt Sutton i really appreciate your reply. I got to the site thru google and Im trying it out atm.
Takes a while so I will reply here later when my account password hopefully is recovered.
@Emmitt Sutton it worked and I finally got access to my account again. Im so happy:D
Thank you so much you really help me out !
@Stetson Dayton You are welcome :)
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