Just to clarify, breaking the phosphate bond is an endothermic process, ie it takes energy, not releasing. Bond forming is exothermic because you are going from higher energy to something normally lower in energy. Thus, the hydrolysis is what is producing the energy, but via the bond formed.
I have learned about ATP on a Biological level several times and never understood it, after watching your organic chemistry series and now this series it is like I can relate everything in life to these things! I love it! Thank you Professor Dave
it took me hours reading textbooks about ATP and I didn't understand a word.. but I watched your 4-minute and I got it all!! thank you so much. I subbed btw.
You teach so clearly and great! I'm just at the second term of Health science bachelor and my native language is not English and i really needed a source like your channel to better understand biology and chemistry! Thank you so much
Doing Keto & Carnivore diets so learning about metabolism. Being an Ancient Greek teacher, I am amazed at how many of these words come from Ancient Greek. βιος συνθεσις συνθετικος (from verb συντιθεμι) μεταβολικος (from verbs βαλλω, μεταβαλλω) αναβολικος (from verb αναβαλλω) καταβολικος (from verb καταβαλλω) θερμος δυναμικος (from verb δυναμαι)
During 3:18-3:24, what do you mean by "the energy can be converted into the energy needed to promote a reaction"? Great video as always...let's get him to 100K subscribers people!
Great, Thank you! And also one more thing...just to be clear, it is the breaking of the phosphate-phosphate bond during ATP hydrolysis that releases energy, correct?
that's right! the repulsion between the oxyanions is a kind of potential energy, and when a phosphate leaves, the molecule goes to a lower energy, which means that energy can be transferred to something else.
Wow! Thank you. I was having some real confusion about the above question. Also, your quick responses are amazing! I really needed that reply ASAP and you came through. Thanks again!
@@ProfessorDaveExplains How exactly is that energy transferred? I imagine it's not simply kinetic energy. What sort of energy is it, and what carries it? How is it given and how is it received?
In chemistry we talk that breaking bonds require energy and it's an endothermic reaction .Then why breaking the bonds between phosphate groups releases energy here?
These videos are truly excellent. Justr one question I have for you: do you do these videos by yourself? And do you have all this knowledge on you already or do you have to study before? (both of these two options are equally awesome)
yep it's a one man show! organic chemistry content i recited from memory from lectures i had given. general chemistry i wrote more or less from memory as well. biochemistry and physics i had a working knowledge but i consulted textbooks as i wrote, and i will rely on other sources more and more as i move into topics that i have less of a knowledge base with, like most areas of biology which are coming up soon!
Q? When ATP changes to ADP+Pi in biochemical reaction we count it as one ATP consumption, and when ATP changes to AMP+PPi again we count it as one ☝️ ATP consumption!why?what is the difference between their energy releasing?
How do molecular machines like triple-A ATPases work? It is known that they do work upon the hydrolysis of ATP+H2O to ADP+Pi, but how is this converted into mechanical energy? And how comparable are these -30 kJ mol-1 compared to the constant random noise of the environment these molecular machines are in?
Thx for the explanation. But I have a problem with potential and kinetic energy. The energy that we're using is kinetic energy right? Why does this energy run out? Where does it go? Does it turn into potential energy? At this point why doesn't it stay kinetic energy?
Is the potential energy from all O- groups repelling each other stored in the phosphate-phosphate bonds? If so, that must mean that the electrons that constitute the bond are high-energy. Furthermore, when this bond breaks, the electrons are able to enter a lower energy state, and release energy in some form of electromagnetic radiation. However, wouldn't this violate the well-established rule in chemistry which states that: MAKING bonds RELEASES energy and BREAKING bonds ABSORBS (or REQUIRES) energy? This question can be expanded to all molecules in general. When we break the bonds in a molecule of glucose in glycolysis, for example, their electrons are moving down to a lower energy state. How then, can the above rule be true? I'm not challenging the foundations of chemistry here, I just want to understand the logic behind them.
so it's not necessarily in the covalent bonds themselves, it's in the repulsion between the formal negative charges. so it's like a compressed spring, it sits higher in potential energy. when the spring is allowed to expand, it will go to a lower potential energy, and that energy that is released can go towards pushing an object, like a pinball springing into play in a pinball machine. when a phosphate group is transferred there is no net change in the number of bonds before and after, it is just a transfer of energy.
Utmost appreciation for you through and academic explanation. Are you familiar with “metabolic carts” often refered to as just “met carts” Could you explain what is going on in these machinery to measure exhaled carbon dioxide via gas analyzers and other associated met cart hardware? Thanks for your work
As an exercise physiologist major working with this system, my professor doesn’t do a great job of explicitly pointing out how it works. Just curious if you were familiar with this, I really look up to perspective on anything science related!
@@ProfessorDaveExplains Q? When ATP changes to ADP+Pi in biochemical reaction we count it as one ATP consumption, and when ATP changes to AMP+PPi again we count it as one ☝️ ATP consumption!why?what is the difference between their energy releasing?
ILOVE YOUR Approach to teach ,always attract me towards your ways of teaching ,you are great professor''''.we have been long history with ITALY.IAM FROM ETHIOPIA.
that's the just the conformation that's most energetically favorable! probably some kind of interactions happening between nucleotides from one helical turn to the next, kind of like interactions between amino acid residues in an alpha helix.
glycogen can be broken down to give individual glucose units which are metabolized to produce ATP, which can be used as an energy source to fuel other cellular processes.
This is way easier to digest than my lecture, thank you chemistry jeesus.
😂😂😂
Chemistry jeesus 😂😂😂😂😂
it is easier to catabolize this video than your lecture
Thanks, Your unique way of explaining complex topics in such a simple way is really helpful. Please upload more videos in this ATP series.
Just to clarify, breaking the phosphate bond is an endothermic process, ie it takes energy, not releasing. Bond forming is exothermic because you are going from higher energy to something normally lower in energy. Thus, the hydrolysis is what is producing the energy, but via the bond formed.
I have learned about ATP on a Biological level several times and never understood it, after watching your organic chemistry series and now this series it is like I can relate everything in life to these things! I love it! Thank you Professor Dave
May I ask on what kinds of things is it?
How did it relate to you?
it took me hours reading textbooks about ATP and I didn't understand a word.. but I watched your 4-minute and I got it all!! thank you so much. I subbed btw.
Its Mona hey cutee pie
fucking pervert
@@deepanshuadhikari4724 is it bob or is it vagana?
reading about a topic in too much detailing in books is actually confusing....its like missing the forest for the trees.....
You teach so clearly and great! I'm just at the second term of Health science bachelor and my native language is not English and i really needed a source like your channel to better understand biology and chemistry! Thank you so much
omg that part about thermodynamic principles governing these reactions. I've been wondering about that since forever! Thank you Professor Dave!
Have a paper go do in few hours and he just simplified my 200+ slides of biochemistry.... ❤ thank you Prof Dave 🙏🏾🙏🏾 ....
Excellent videos, how come you don't get more attention? Please don't stop
hoping they will catch on soon! spread the word to everyone you know. but don't worry, i'm going to make a lot more of these.
@@ProfessorDaveExplains they definitely did haha
Doing Keto & Carnivore diets so learning about metabolism. Being an Ancient Greek teacher, I am amazed at how many of these words come from Ancient Greek.
βιος
συνθεσις
συνθετικος (from verb συντιθεμι)
μεταβολικος (from verbs βαλλω, μεταβαλλω)
αναβολικος (from verb αναβαλλω)
καταβολικος (from verb καταβαλλω)
θερμος
δυναμικος (from verb δυναμαι)
You are a great teacher give highly concentrated high quality knowledge facts & sciences. Thank you very much.
Thank you
During 3:18-3:24, what do you mean by "the energy can be converted into the energy needed to promote a reaction"? Great video as always...let's get him to 100K subscribers people!
it just means that phosphorylation is a common method a cell can use to get reactions to happen, all kinds of enzymes do it. woohoo 100k!
Great, Thank you! And also one more thing...just to be clear, it is the breaking of the phosphate-phosphate bond during ATP hydrolysis that releases energy, correct?
that's right! the repulsion between the oxyanions is a kind of potential energy, and when a phosphate leaves, the molecule goes to a lower energy, which means that energy can be transferred to something else.
Wow! Thank you. I was having some real confusion about the above question. Also, your quick responses are amazing! I really needed that reply ASAP and you came through. Thanks again!
@@ProfessorDaveExplains How exactly is that energy transferred? I imagine it's not simply kinetic energy. What sort of energy is it, and what carries it? How is it given and how is it received?
You’re such a lifesaver.
Pls why does the hydrolysis of ATP to AMP produce lesa energy than the hydrolysis of ATP to ADP?
Thanks for video!
Your simply THE BEST!
Thank you.🙏🏼
L like the way you explain your work for me to understand
Thanks!! This is such an awesome video!! Super helpful! Thank you so much!
your videos are very good! I really like the way you teach. I'm looking forward to watch the rest of the videos
This was really helpful
Holy moly, I understood this more than my hour and a half lecture
Nicely done Dave!
Thanks so much Prof. Dave
My exams was super successful ❤️❤️
🇳🇬
Mantap brooo . Mudah dipahami
Ties in Orgo concepts and physics....great!
In chemistry we talk that breaking bonds require energy and it's an endothermic reaction .Then why breaking the bonds between phosphate groups releases energy here?
Same problem arises with me also
very nice
Hey professor Dave 👋
thanks prof.....you are best I have ever seen
Thanks
Emergent complexity is so cool.
Best example I like your videos think sir
0:03 2nd reason fr being here❤
These videos are truly excellent. Justr one question I have for you: do you do these videos by yourself? And do you have all this knowledge on you already or do you have to study before? (both of these two options are equally awesome)
yep it's a one man show! organic chemistry content i recited from memory from lectures i had given. general chemistry i wrote more or less from memory as well. biochemistry and physics i had a working knowledge but i consulted textbooks as i wrote, and i will rely on other sources more and more as i move into topics that i have less of a knowledge base with, like most areas of biology which are coming up soon!
You're the man, man. Great respect for you!
Thanks very helpful
Q?
When ATP changes to ADP+Pi in biochemical reaction we count it as one ATP consumption, and when ATP changes to AMP+PPi again we count it as one ☝️ ATP consumption!why?what is the difference between their energy releasing?
How do molecular machines like triple-A ATPases work?
It is known that they do work upon the hydrolysis of ATP+H2O to ADP+Pi, but how is this converted into mechanical energy?
And how comparable are these -30 kJ mol-1 compared to the constant random noise of the environment these molecular machines are in?
nice organisation
You mean "organization".😆
Am I stupid if I watch this twice and still can barely tell you metabolism is making energy
you are good bravo
Come for the debunking of crazies, stay for the cool science
this was helpful
was here before 1 mil nice.
Thx for the explanation. But I have a problem with potential and kinetic energy. The energy that we're using is kinetic energy right? Why does this energy run out? Where does it go? Does it turn into potential energy? At this point why doesn't it stay kinetic energy?
Is the potential energy from all O- groups repelling each other stored in the phosphate-phosphate bonds? If so, that must mean that the electrons that constitute the bond are high-energy. Furthermore, when this bond breaks, the electrons are able to enter a lower energy state, and release energy in some form of electromagnetic radiation.
However, wouldn't this violate the well-established rule in chemistry which states that: MAKING bonds RELEASES energy and BREAKING bonds ABSORBS (or REQUIRES) energy?
This question can be expanded to all molecules in general. When we break the bonds in a molecule of glucose in glycolysis, for example, their electrons are moving down to a lower energy state. How then, can the above rule be true? I'm not challenging the foundations of chemistry here, I just want to understand the logic behind them.
so it's not necessarily in the covalent bonds themselves, it's in the repulsion between the formal negative charges. so it's like a compressed spring, it sits higher in potential energy. when the spring is allowed to expand, it will go to a lower potential energy, and that energy that is released can go towards pushing an object, like a pinball springing into play in a pinball machine. when a phosphate group is transferred there is no net change in the number of bonds before and after, it is just a transfer of energy.
Utmost appreciation for you through and academic explanation.
Are you familiar with “metabolic carts” often refered to as just “met carts”
Could you explain what is going on in these machinery to measure exhaled carbon dioxide via gas analyzers and other associated met cart hardware? Thanks for your work
There is really nothing on the web that clearly explains the phenomena of met cart technology. Is it secretive, or just not of popular interest?
As an exercise physiologist major working with this system, my professor doesn’t do a great job of explicitly pointing out how it works.
Just curious if you were familiar with this, I really look up to perspective on anything science related!
Hmm sorry I'm not familiar with that!
@@ProfessorDaveExplains Q?
When ATP changes to ADP+Pi in biochemical reaction we count it as one ATP consumption, and when ATP changes to AMP+PPi again we count it as one ☝️ ATP consumption!why?what is the difference between their energy releasing?
Cheer~~~the chemical processes that occur within a living organism in order to maintain life.😊
Nice
Thanks Dave :-D
ILOVE YOUR Approach to teach ,always attract me towards your ways of teaching ,you are great professor''''.we have been long history with ITALY.IAM FROM ETHIOPIA.
I just wanna ask, why the adenine base in particular why not guanine or thymine???
ADAMSIN LAN DAVE MUHTEŞEM
SEN KRALSIN HOCAM
Is formation of AMP as common as ADP? Thanks!
Hi,sir kindly share ppt of this lecture
Good very good
amazng-est video >o< thank you so much!
Question, is taking atp pills beneficial to me
This is some good shit
I love your intro a lot lol
ATP is formed from ADP by using which enzyme. ???
ATP synthase, most notably. check out my tutorials on cellular respiration, in three parts.
is ATP hydrolysis the exact opposite of phosphorylation?
yeah pretty much, phosphate group off, phosphate group on
0:44
So which one grows muscle?
Or both?
In simple english
Upload More bio topics please
an entire biology course is coming starting this summer!
Professor Dave Explains thanks professor
I don't understand about physiology how help me Dr
sir why DNA is helical
.?????
that's the just the conformation that's most energetically favorable! probably some kind of interactions happening between nucleotides from one helical turn to the next, kind of like interactions between amino acid residues in an alpha helix.
thankuuu sir
When your mom and dad had good times
Do you like wine Dave?
Absolutely, I do!
Does it build muscle?!
Thank you chemistry Jesus
Everyone grab your 'I was here before 1 million' tickets here
Thank me later
Be my mentor
Is the direct energy source ATP or glycogen?
and thanks.
glycogen can be broken down to give individual glucose units which are metabolized to produce ATP, which can be used as an energy source to fuel other cellular processes.
Ahhhh Biosynthetic Pathways
Catabolic and Anabolic
samaj nai ayaya
🎉❤🎉🎉🎉🎉😊
Alzheimer's disease and WHIM are both a receptor is affected?
Thank you
i'm not sure!
Fat protein conservation
What concept would you need to first know the basics in order fully understand the concept of Metabolism?
certainly organic chemistry, and then a decent amount about the structure of biomolecules.
ممكن الترجمه الى اللغه العربيه
شرج جميل جداً🌷
Oh god. I hope the flat earthers don't ever come across this...I can hear them saying "ELECTROMAGNETISM MAKES LIFE WORK, SO WHY NOT GRAVITY!!!1!"