Basic Renal Function: Clearance and GFR

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  • Опубликовано: 1 ноя 2024

Комментарии • 64

  • @lavendershi7071
    @lavendershi7071 4 года назад +6

    This serie of videos really help me a lot with the calculation. Thank u very much!

  • @user-zc4cu6rz1d
    @user-zc4cu6rz1d 2 года назад +5

    1:42 If the substance is reabsorbed and the urine conc. halved, why hasn’t the plasma conc. changed?

  • @shoshohamad9324
    @shoshohamad9324 7 лет назад +4

    I am from Egypt, thank you very much for the valuable information and the interesting dynamic explanation. Thank you for your great efforts. Thank you

    • @rem2510
      @rem2510 6 лет назад

      Appreciate video content! Excuse me for butting in, I am interested in your thoughts. Have you ever tried - Trentvorty Perfection Kidney Theorem (just google it)? It is a great one off product for improving kidney function minus the normal expense. Ive heard some super things about it and my BF at very last got cool results with it.

    • @alex-ip1er
      @alex-ip1er 6 лет назад

      Cheers for the Video! Sorry for chiming in, I would appreciate your initial thoughts. Have you researched - Trentvorty Perfection Kidney Theorem (just google it)? It is a smashing one of a kind product for improving kidney function without the normal expense. Ive heard some unbelievable things about it and my close friend Aubrey finally got astronomical results with it.

    • @bondangustariko7282
      @bondangustariko7282 4 года назад

      ♣♣♣Christopher Kenneth's experience of suffering from chronic kidney disease. And how did he deal with it. As you Christopher experiences the fatigue, swollen ankles, sleep deprivation that characterizes CKD sufferers knows that CKD is getting worse - and ultimately causing damage to your body that you can't repair, worrying about the end game for CKD: hours a day on a dialysis machine, kidney transplant. premature death, but she found out from her own doctor that many sufferers have now completely relieved their CKD symptoms. Because CKD is no longer a mystery like it used to be. We now know why it happened - which is why we now know how to stop it in its tracks. For more information click here: tinyurl.com/y5no2zq6?DerNAde4 > ♠♠♠

    • @denisuprianto2483
      @denisuprianto2483 4 года назад

      ♠♠♠I tried to find out about "what foods are good for stage 3 kidney disease?" for a while now, and I think it has helped. This is an excellent program for finding ways to help your kidneys function without the normal cost. I have heard some great things about him and my friends have had tremendous success with him. For more information click here: tinyurl.com/y5no2zq6?DerNAde8 > ♣♣♣

  • @Duckguts1
    @Duckguts1 6 лет назад +1

    Thankyou for best illustrations dey hv saved my time and clear da concept 👍👍👍👍

  • @ishaq542
    @ishaq542 Год назад +1

    Thank you, sir!

  • @nassebella9149
    @nassebella9149 8 месяцев назад

    Thank you that was helpful ❤

  • @xmax700
    @xmax700 3 года назад +4

    This war amazing Thank you very much. perfect explain

    • @vladbrad1389
      @vladbrad1389 2 года назад

      You're right it's a war it's an amazing war, and we're fighting it 💪

  • @Ahmed_Abdulsattar7
    @Ahmed_Abdulsattar7 2 года назад +1

    Amazing
    Thanks bro 🙏

  • @adityahs2
    @adityahs2 7 лет назад +1

    do u prepare content from any one particular text books...?
    like berne and levy is what i follow..

  • @mdabdulhafeezmalik45
    @mdabdulhafeezmalik45 6 лет назад +2

    Beautyfully explained

  • @paulafrengul9761
    @paulafrengul9761 8 лет назад +2

    Very clear and helpful thank you

  • @antoniomunaretto9147
    @antoniomunaretto9147 4 месяца назад

    i have a question. If the clearance of a substance that is only filtered and not reabsorbed or secreted is equal to the GFR, so 125ml/min. How is that in the first example you made the clearance is only 40?

    • @LanceMillerPhD
      @LanceMillerPhD  4 месяца назад +1

      Hi, That's a great question. With the first example of clearance being 40 ml/min, I can see how you have a question and how it does not match with a clearance of 125 ml/min.
      In the first question where the clearance is 40 ml/min, this GFR is well below normal. I used these numbers to illustrate the role of filtration, reabsorption, and secretion on clearance (GFR) rather than illustrating a typical GFR.
      To get a clearance or GFR of 125 ml/min, we could use the following numbers: U = 100 mg/mL, V = 1 ml/min, and P = 0.8 mg/ml. This would give a GFR of 125 ml/min.
      I hope that helps clarify things and sorry for any confusion.
      Best, Dr. Miller

    • @antoniomunaretto9147
      @antoniomunaretto9147 4 месяца назад +1

      @@LanceMillerPhD okay now is clear, thank you very much for the clarification.

  • @mariammarello9965
    @mariammarello9965 7 лет назад +1

    thank you very very much ,, your video is the best

  • @rebornmmmmuch
    @rebornmmmmuch 4 года назад

    Thanks this really helps💘

  • @CristianoRaashid77
    @CristianoRaashid77 4 года назад +1

    This was really helpful thank youuu!!!!

  • @lionsinescanor373
    @lionsinescanor373 Год назад

    very helpful

  • @ilovejesus9303
    @ilovejesus9303 7 лет назад

    Thank you so much for your time, this was helpful

  • @azadparray1659
    @azadparray1659 Год назад

    I have creatinine level between 1.1 to 1.25 from last three years now it is 1.23
    Bp is 100/60
    Sugar fasting below 100
    No protein in urine
    USG is normal
    Is there any serious for my kidneys

    • @LanceMillerPhD
      @LanceMillerPhD  Год назад

      Your blood pressure and your fasting glucose are great, and the fact that you don’t have protein in the urine and are all positive signs and suggest your kidneys are healthy. Also, your serum creatinine is at the upper end for a male. That’s important to know that serum creatinine is only an estimate of glomerular filtration rate and can vary based on age, gender and muscle mass. as always, this does not replace advice from your physician.

  • @jamshedfbc
    @jamshedfbc 5 лет назад +1

    Creatine filtered but not reabsorbed or secreted. Where would it go then?

    • @LanceMillerPhD
      @LanceMillerPhD  5 лет назад +1

      Creatinine is excreted in the urine.

    • @ollanadajikhatikha479
      @ollanadajikhatikha479 4 года назад

      Christopher Kenneth's experience of suffering from chronic kidney disease. And how did he deal with it. As you Christopher experiences the fatigue, swollen ankles, sleep deprivation that characterizes CKD sufferers knows that CKD is getting worse - and ultimately causing damage to your body that you can't repair, worrying about the end game for CKD: hours a day on a dialysis machine, kidney transplant. premature death, but she found out from her own doctor that many sufferers have now completely relieved their CKD symptoms. Because CKD is no longer a mystery like it used to be. We now know why it happened - which is why we now know how to stop it in its tracks. For more information click here: tinyurl.com/y5no2zq6?DerNAde7 > ○○○

  • @ranadr2788
    @ranadr2788 7 лет назад

    Very much helpful . Thanks ♡

  • @leahbeechey2898
    @leahbeechey2898 3 года назад

    Is clearance & eGFR the same thing?

  • @danam7172
    @danam7172 7 месяцев назад

    thank u sm wow

  • @leticiamagalhaes3437
    @leticiamagalhaes3437 4 года назад

    The volumen of plasma needed to pass through the kidneys in a given amount of time un order to excrete a given quantily of substance in the Urine.

  • @ranahanna160
    @ranahanna160 6 лет назад

    a question: if a substance is filtered, how come we have some of it left in the peritubular capillaries to secrete?

    • @LanceMillerPhD
      @LanceMillerPhD  6 лет назад +11

      That’s a great question. It’s because not all of the fluid and substances that pass through the glomerular capillaries is filtered.

  • @ahmedelgazar6983
    @ahmedelgazar6983 5 лет назад

    Thanks a lot for this video💕

  • @TheSummerOf86
    @TheSummerOf86 7 лет назад +2

    Awesome, thanks!
    (maybe add 'RPF' and/or 'PAH' to the title)

  • @yasasvihasanjana9792
    @yasasvihasanjana9792 7 лет назад

    Thanks.... clearly explain

  • @birdlynn417
    @birdlynn417 6 лет назад

    My blood test GFR was 86. Normal is 89 and over. Should I be concerned?

    • @LanceMillerPhD
      @LanceMillerPhD  6 лет назад

      That is good question and is best answered by your doctor. However, to get a better idea about one thinks about the GFR test, I recommend visiting the following link. www.kidney.org/atoz/content/gfr. The link provides more information about the test, relates values to renal function, and the role of additional tests, i.e., proteinuria, in making a proper diagnosis.
      In summary, a GFR of 86 suggests a mild loss of kidney function (e.g., your kidneys are 86% functional). However, you would have to have your GFR measured for about three months and measure the amount of protein in your urine to make an accurate assessment of renal function (see link). In addition, if your blood pressure is consistently elevated (i.e., >130/80 mm Hg) I would highly recommend you have this checked out sooner rather than later.
      I wish you well and hope that all turns out for the best.

    • @howardrice2470
      @howardrice2470 4 года назад

      This is all bs
      I been living for 40 years with less than 50 per cent filtration rate with no problems except doctors. Everybody is different. $$$$ is doctors goal! BS

  • @ghassanauf8103
    @ghassanauf8103 4 года назад

    PHD for this !!!!!

  • @supunjayawardhana3695
    @supunjayawardhana3695 3 года назад

    thank you

  • @matthewreddick9334
    @matthewreddick9334 6 лет назад

    Why would a less concentrated plasma yield a higher clearance? seems counterintuitive.

    • @suhaibfarooq3343
      @suhaibfarooq3343 4 года назад

      Simply because the plasma is less concentrated, more amount of it will be required to flow through the kidneys to excrete a given amount of solute.

  • @مريم-ت9م
    @مريم-ت9م 3 года назад +2

    Awesome

  • @rafishikder8110
    @rafishikder8110 2 года назад

    THNX

  • @indira1719
    @indira1719 3 года назад

    this was greaaaaat

  • @dajanae.d2535
    @dajanae.d2535 3 года назад +1

    💝💝💝

  • @fernandofrossard8612
    @fernandofrossard8612 3 года назад

    Helpful!

  • @mouniraboud9010
    @mouniraboud9010 7 лет назад +1

    ur the best :) thnx

  • @Gh-ef4yq
    @Gh-ef4yq 2 года назад +1

    👍

  • @ScholarIdeavideos
    @ScholarIdeavideos 6 лет назад

    Thanks

  • @vgvhfgg7385
    @vgvhfgg7385 7 лет назад

    very nice

  • @esha-3296
    @esha-3296 4 года назад

    Ei video ta banglay upload kora jayna? 😑

  • @b.s.a.agamer7902
    @b.s.a.agamer7902 5 лет назад

    Thank you

  • @abuammarali5521
    @abuammarali5521 7 лет назад

    Thanks