The Central Nervous System
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- Опубликовано: 12 сен 2024
- Welcome to Sureena Speaks©!
And welcome to the central nervous system (CNS). Most of the information is based on Chapter 4 of the BNF and will hopefully aid your understanding of the CNS. The sections covered are:
-Hypnotics & Anxiolytics: 00.41-6.49
-Antipsychotics: 6.50-16.40
-Antidepressants: 16.40-24.02
-CNS Stimulants & ADHD: 24.15-25.00
-Drugs used in obesity: 25.06-26.19
-Drugs used in nausea and vertigo: 26.20-30.08
-Analgesics: 30.08-35.11
-Neuropathic pain: 35.12-37.06
-Antimigraine medication: 37.06-40.49
-Antiepileptic medication: 40.49-47.20
-Parkinsons Disease: 47.20-50.34
-Drug Dependency: 50.34-55.46
-Dementia: 55.47-57.02
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Happy Revisings!
Hey Sureena, I passed my pre-reg 2 days ago and I genuinely owe you this pass. Your videos were literally my staple for last few months before the exam! Thank you so much for Sureena Speaks, it's a great initiative for pharmacy student/professionals! All the best in your future ventures and looking forwards to have some great stuff for qualified pharmacists too :)
Nazat Fahmi Hiya, CONGRATULATIONS on passing!! And thank you for your beautiful words, it genuinely means so much to me that the videos helped you! Good luck with all that you do and thank you for your support! :D
hi dear, i passed pre reg a few years ago, and all that thanks to your videos! now I have worked for a few years in community, I am venturing into becoming a hospital pharmacist in the next few days. I am just refreshing through everything in the BNF. You really motivates me a lot and make everything easier. Thank you, you are a star!!
Really appreciate your kind words! Good luck in your new role!! :)
This is super helpful thanks! A couple of things which I would find helpful, not sure about other people.
- a podcast of just the audio to listen to on the way to work.
- pictures shown via picture instead of video with the audio running behind.
Incredible work, if I pass, I owe it to you!
hiya, just curious to know how do you transfer videos to podcast?
aww that's so sweet of you to say! good luck with your revision!!
Amazing work! I'm doing my pre reg in England but I travel to scotland often. This is just what I need for my journies. Thank you so much!
Aww you're very welcome :)
hi ihram
how's the journey
Great hahaha
what a pleasant surprise
You are such an inspiration Sureena ... Bless you
If you're looking for detailed drug summaries, you may also find our videos useful!
Sureena thank you so much for your videos!! I find them so so useful and your positivity makes everything more bearable!! Exam is 2weeks today - fingers crossed!!
Wishing you all the luck!! You can do this!! :)
this is such a great video thanks u are a star
that's so sweet of you to say, glad you liked it! :)
SSRIs and NSAIDs interact due to increased risk of bleeding, that is the only documented interaction between them in the BNF. Tramadol, Antidepressants etc will interact with SSRIs and cause serotonin syndrome as they increase serotonin levels.
Yep that is correct however there has been research to suggest the possibility of SSRI + NSAIDs together causing serotonin syndrome, it is also something that I've seen cropping up in practice. But yes agreed the main interaction of SSRIs and NSAIDs is increased risk of bleeding :)
www.ehealthme.com/ds/ibuprofen/serotonin%20syndrome/
I thought nsaids and ssri interaction causes increased risk of bleeding, not serotonin syndrome?
you may find patients on SSRI's saying that they keep getting really bad red rashes (particularly on their arms from what I've noticed) and severe headaches and when you ask them if they've taken anything recently you'll be suprised how many say ibuprofen. The combination of the two can lead to serotonin syndrome - not in all cases as side effects can be variable but it's something to watch out for and a good counselling point to advice patients on SSRI's :)
Very best
Thanks for the helpful video Sureena. does orlistat affect the absorption other drugs such as metformin? X
Hiya! Care should be taken if it's taken with antiepileptics, antiretrovirals and medicines with a narrow therapeutic index, for more info: bnf.nice.org.uk/drug/orlistat.html#interactions
Can I know at 5:00 , Temazepam is better than others because it has ...? I couldn't quite catch that one. If you can have some words/ diagrams as aid that would be very helpful.
mrorange330 "temazepam is better than others because it doesn't have a hangover effect" :) sorry for the late reply - I didn't get a notification for your comment for some strange reason :S
Thanks a lot for your videos.
Can you please add a transcript for the CNS.
Sorry I don't have a transcript I'm afraid
Hi Sureena, Can I just ask where it is stated that fluoxetine needs to be stopped for 5 weeks before switching to another antidepressant? Thanks
Hiya! so it is specifically when fluoxetine is switched to a MAOI that a 5 week gap is recommended. There are a range of websites to support this for example here: patient.info/doctor/selective-serotonin-reuptake-inhibitors hope that helps :)
Hi when you discussed migraines you didnt mention whether you can offer co-codamol for migraines if paracetamol, aspirin or ibuprofen are not effective, so would co-codamol be offered next if the three drugs mentioned above did not provide therapeutic efffect or would you jump straight to a triptan?
Also if someone coes in pharmacy and lets say they havent been diagnosed with migraines but as a pharmacist you can tell that its defo a migraine can you sell the sumatriiptan?
Lastly do you always refer a pregnant women asking for nausea tx or can yiu sell promethazine otc to help them?
Hiya! Co-codamol isn't typically recommended for migraines, refer to migraines in the BNF for more information :) some pharmacies provide questionnaires for patients who they believe are suffering from migraines, which can be a really useful tool. As a pharmacist you can use your clinical judgement to determine whether someone who suffers from migraines would benefit from sumatriptan. With regards to your question about nausea in pregnancy, refer to the NHS website on this topic as well as the BNF/NICE guidelines. Promethazine can only be sold as per it's licensing and via your clinical judgement on the situation :)
I thought that if a person is on an SSRI, they can take the odd few NSAIDs for a week or 2? Correct me if I’m wrong please. Thanks!
Hiya! So you would have to look at it in a case by case basis. I've had patients who have had to be on both SSRIs and long-term NSAIDs but usually they're closely monitored for any signs of bleeding (or at least they should be!) It's always worth making sure the patient is aware of the potential interaction and that they know what signs of bleeding are. Hope that helps :)
Thanks for the mmmmmmemory aid for marrow suppression haha
Seditive paradoxical affects being aggression? You ever had to deal with a sleepy 5 year old? Haha