GLUT 1-4 Glucose Transporters | MCAT
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- Опубликовано: 6 сен 2024
- Today we go over GLUT transporters 1-4, covering their biochemical and physiological relevance. GLUT 4 and 2 and the most high yield, with GLUT 4 being slightly more important than GLUT2.
The 2021 MCAT schedule is released! The normal length of the exam is back, which means good news and bad news: the good news is that you get a lunch break, the bad news is that the test is a marathon again.
Comprehensive Amino Acid Playlist: bit.ly/3sMGBUG
Check out Aratasaki, the beat maker behind my intro and outro: bit.ly/2Pma5v0
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GLUT 1-4 Glucose Transporters | MCAT 2021
GLUT 1-4 Glucose Transporters | MCAT 2021
GLUT 1-4 Glucose Transporters | MCAT 2021
#glucose
How's it going everyone? One mnemonic you can use to remember the role of GLUT4 is that GLUT4 is released when you are "GLUTtonous 4 sugar," meaning GLUT4 is mobilized when blood sugar is high.
Another good one is GLUT2 for 2 much blood sugar
A person has a nonsense mutation in a gene that codes for glucagon? Which cells of the pancreas expresses this gene?
A. villi cells
B. alpha cells
C. beta cells
D. most islet cells of the pancreas
A person has a proliferative tumor in the delta cells of the pancreas? How is Growth hormone activity affected?
A. GH levels are lower since somatostatin is always produced at high levels
B. GH levels are higher since somatostatin is produced at high levels
C. GH levels are lower since somatostain is produced at abnormally low levels
D. GH levels are higher since somatostain is produced at low levels.
Where's GLUT-4 located?
What about GLUT-2's location?
Answers: B, A, muscle cells/adipocytes, liver/pancreas
The MCAT world has a new legend in the making
😂😁
This is a pretty good video! I have two sets of review books and neither one mentioned the glucose transporters whatsoever! So, thank you.
I believe Kaplan discusses glucose transport in their section before glycolysis! In case you wanted to take a look at that.
Need more people like you at the NHS!
Thank you Boris, very cool!
I have only skimmed the video (shame on me :( ), but GLUT1 and 4 are also expressed in the cardiac muscle. I don't believe you're mentioning this. Is there a reason?
Correct, I don't mention this! I don't mention it because it is historically unlikely to be tested on the MCAT.
Further, given that it is not tested on Step 1 nor taught in many medical schools (which is much more detailed in biology), I'd be shocked to see it tested on the MCAT.
@@medcatmcat alright, thx for clarifying :)
Hey MedCat, why do RBC’s need glucose? They don’t have mitochondria 😅
RBCs still need ATP! If they don't have it, a whole number of pathologies can result. They get the ATP through glycolysis, which starts with glucose.
One example (not MCAT relevant, but you'll learn in med school) is pyruvate kinase deficiency, a genetic condition that results in anemia. There's not enough ATP to support the RBC membrane, and as a result, the RBCs get destroyed.
@@medcatmcat ah thank you so much, appreciate it
I think better on ketones🙂
Many do!