Isotretinoin Accutane
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- Опубликовано: 11 окт 2024
- Isotretinoin originally marketed as Accutane should be limited to those with severe nodular or cystic acne unresponsive to traditional therapy with topical agents and oral antibiotics. Due to an enormous number of lawsuits, Accutane has not be available for over a decade. Substitutes include Claravis, Absorica and Amnesteem.
Isotretinoin is available only through the iPLEDGE program which requires reading and signing an informed consent form. This program was developed by the drug manufacturers in response to pressure from many organizations to remove isotretinoin from the market. The central issue involved an enormous incidence of birth defects associated with even limited exposure in pregnant women.
Two negative pregnancy tests and acceptable contraception are required from one month before isotretinoin to after therapy in fertile women. Monthly blood tests are required although one study takes exception this.
In 2005 the FDA issued an alert to consumers regarding an association of isotretinoin with depression and suicidal thoughts. Currently dermatologists cite studies exonerating isotretinoin in this regard while psychiatrists still believe a link exists. Isotretinoin may decrease metabolism of the frontal cortex and decrease availability of serotonin. It may also reduce neurogenesis in the hippocampal region of the brain.
Isotretinoin may clear acne in just one 15-20 week course of therapy. Side effects trouble almost everyone during therapy. Isotretinoin reduces bone density perhaps permanently and may predispose to osteoporosis.
There is such a thing as accutane. I live in Canada and we still have it under the name Roche Accutane. I didnt have to sign anything or do any paperwork to start taking it, and a month's supply of accutane cost me $9. I am so thankful for our healthcare system.
David Yup I am Canada too. My derm wrote me a prescription for Accutane - it is here in Canada but I ended up on the generic Clarus.
Yes true. I was shocked here in canada still has roche accutane. My derm first prescribed me epuris and it have me chest pains. Then I asked about another brand and she told me Accutane is still available.
Bruh it costs me $114 per month supply 😅
@@andrewj.romero2580 costs me £9.50
Lol in India it costs less than $0.07 For 40 days supply ..Maybe because we are the pharmacy of the world ?
This doc is just a ray of sunshine. The benefits far outweigh the risks. Talk to a dermatologist and avoid the psychological effects that severe acne causes. You don’t have to endure debilitating acne!
I took Accutane in 2008 for 5 months in total. I have not had a single pimple since. The side effects were rough during treatment and I had to buy Aquaphor to spread inside my nose and constantly apply eye drops since it dried everything out. But I thankfully dodged any long-term side effects. In terms of permanently ridding acne, it is a miracle drug. I remember I had to take this questionnaire each month at the pharmacy and the dermatologist wanted monthly blood tests to check my liver. It was intense how tightly regulated this was and it is not even a controlled drug. I also lucked up in that my insurance covered all 5 months.
What dose were you on? If u remember
@@mattheww1779 the max. Two pills a day at 40 milligrams each with a fatty meal or glass of milk. I took 300 pills total.
It costs $49 Australian dollars for 60 capsules 20mg but 6.60$ for concession (low income benefit)
What a comprehensive review. I had to turn you down to .5x just to keep up, haha.
The pills are so expensive in the States. Here in Germany it's free you just need a doctor's prescription and you just get it at the pharmacy
Not true. I thought the same but I watched an accutane video from a black lady in Atlanta Us. She payed 100% out of pocket $40/month for it. I pay privately in the Uk £69.99/month for generic isotretinoin, sure it would be £10/month on the NHs but I’m comparing like for like what I pay and what the lady in Atlanta pay privately and it’s cheap in America. The only difference is I guess that I can’t my blood test free and they need to pay for theirs
This is an excellent review of Accutane (Isotretinoin), although the early history is not entirely correct. Dr Y
Thank you Dr. Y
I do not care what it’s called. It CURED my nodular acne when I was in my early 50s.
Many of us would have ended our lives without isotretinoin. End of. Worth the risk for anybody who is properly prescribed. I.e horrifically debilitating acne that will not go, ruining your life.
In one month of isotretinoin therapy I developed wrinkles. I'm alredy dishydratated by a psichiatric cure with litium. Today I've interrupted iso because I was worried by the wrinkles. Will my skin be oily again? After I didn't want that but now I realize I was lucky! Oily skins have less wrinkles. Please give me this answer: I'd like to understand If my glands have get smaller forever in one month therapy. I know you aren't a doctor but try to help me please...thank u
If I were you, I would stop. I took acutane in 1998 or 1999. It caused dry lips, but I did not notice wrinkles.
In case you did not catch it, acutane is a synthetic version of Retinol (Vitamin A). What does that mean, you ask? It means that if you just consume Vitamin A daily, your acne should improve.
Vitamin A is a fat-soluble vitamin found only in animal fats like beef tallow, lard, chicken fat and butter, not plant oils.
Replace your plant oils with those fats and start cooking with them and your acne and wrinkles should clear up, and you will loose weight as well. You will be healthier than you have ever been.
I know it was a year ago but damn... do not mix Lithium with any other medication, much less Accutane.
Wow! The guy actually told the truth about Accutane. Obviously not a dermatologist... Might be old enough to remember X-rays being used for acne, though.
I think FAAD in his quals denotes he has his boards in dermatology.
@@Mark_Ocain You're right. FAAD might just yank his certification if they find out he's saying bad things about one of their pet drugs. They still maintain the absurd dogma that Accutane can't induce long-term side-effects, only long-term benefits.
@@willgallaher501nobody said it doesn’t potentially. But when the patients, feel life isn’t worth living with it. The benefits will always outweigh the risks. Though I agree it’s given out like candy too often. I’m 29, only just been prescribed it after horrific cystic acne for 17 years and trying every medication known to man to help it, I can’t wear just a T-shirt in the summer because it gets covered in blood when the cysts burst. The back and sides of my neck have terrible scars that look like I’ve had acid thrown at me, the same with my back and chest. My face has deep gouges in it. I also can’t sleep on my back because of the pain. I have been unable to shave since I was 17 because I get lots of cysts in my beard area and any friction there such as even washing my face flares me up never mind shaving. I’ve never been to a club, a beach, had a partner, I haven’t left my house for 4 years, Etc. sorry for my life story, but I think we can agree that I’m entitled to be prescribed this medication and regardless of what may happen in the future with side effects it’s unlikely I’ll be in a worse position than I’m in now. There’s a place for accutane and that place is the last resort people like me rely on. But as I said before I’ll repeat myself, giving it to these teenage girls who have had some hormonal acne for a year or 2 feels wrong. ( more than anything because it doesn’t even help hormonal acne)
Thank you good sir for your knowledge and sharing.
I am 16 years old, 1.60m tall and have severe acne for which isotretinoin treatment was recommended. However, I have read that this drug blocks growth and since I do not want to stay fixed at 1.60 I am worried. Is this true? I have also been growing visibly lately and I would not want to stop this growth. My short stature could cause me even more discomfort than acne scars. What do you recommend?
Did you grow?
Its so enlighting. Thank you so much
In eu its Roaccutane?
After how long after taking Roa should get pregnant?
Great explanation!
thank you
Thanks!
I used this when it first came out. It helped me tremendously.
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Sir, isotretinoin taken for 20 days pimples gone, later after 4 days i got fever which retained for 4 days took medicine for fever , got rashes all over nt face, 6th day bruffin 600mg post fever in morning got puffy face, tlc count 33000 no sighn of high esinophils and neutrophils rise , liver parameters raised, given corticosteroid (wysalone in the order 40mg/day) ,tlc count 13000 rise in eosinophils 30 and neutrophils, Ige level 14000 fever recurring upto 102 for 2 weeks , continued corticosteroid for 4 weeks . All got better 15 days later psoliosis again went to dermatologist got normal bt again got pimples.... Shall i continue again ??
Feels like you're dying on this but it works well
Is accutane make uterus dry or no please need answer
What happens when a man takes it for 2 weeks and then impregnates a woman? Any effects on the baby? 🤔
Lol i guess not
🙏🏽
i live in germany and we get it completely for free lol
Free? Taxes pay for it. Someone always pays.
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It couses permanent dry skin after treatment for years and years
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@@chrissybasuino7328 for very several causes ofc if there there s no other possible choice.But not as first line wtf this isotretinoine
Lmao. I took it and a few others I know and the dry skin receded after the treatment ended.
@@charlesswitzer8378 Good to know thanks it was like 20 years ago anyway
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