How Does Fluoride Change Your Teeth?

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  • Опубликовано: 25 май 2020
  • Support the channel by joining our newsletter: bit.ly/watchclockwork
    Let's talk about how fluoride ions straight-up change the chemistry of your teeth.
    This video provides a solid introduction to this topic, but can't hit all the important details. Corrections, clarifications and sources are here: bit.ly/clockworkep2
    This channel is created with the support of all our patrons on Patreon: / clockworkshow
    Support the channel directly with a one time donation: www.paypal.me/clockworkshow
    This channel is dedicated to sparking your curiosity about biochemistry, not to being a definitive resource. To help you continue you biochem journey, I'm really excited to partner with Biocord , a Discord server dedicated to bringing together biologists from around the globe! Join the conversation with thousands of life sciences professionals and enthusiasts here:- / discord
    All music is by Jeremy Blake( / redmeansrecording , released on the RUclips Audio Library.
    Intro music: Let's Go Home (bit.ly/rmrlgh)
    Outro music: Lost and Found (bit.ly/rmrlnf)
    The style of this video was largely developed based on tutorials by Ben Marriot: (bit.ly/posterizethis)
    Learn more about tooth formation and chemistry in my post on the subject here: bit.ly/clockworkep2

Комментарии • 124

  • @morganstock4660
    @morganstock4660 3 года назад +113

    Have you considered that the acid sensitivity is as simple as the basicity of hydroxide vs the basicity of fluoride? going from pH 6 to pH 5, you'd see a 10x drop in hydroxide concentration, thus reducing the amount available to remineralize into hydroxapatite. fluoride, however, is a weak base and won't start to protonate until the pH drops below 4ish (given that the pKa of HF is around 3).

    • @Clockworkbio
      @Clockworkbio  3 года назад +51

      Yea, what I learned from the feedback to this video is that I don't remember my pchem fundamentals NEARLY as well as I remember my biochem fundamentals. I bit off more than I could chew--completely forgot to mention pKa in this ENTIRE video, and instead of a real paper, my primary source was an article funded by a toothpaste company. Complete scripting disaster from back to front. This video is _close_ to accurate--but not close enough. However, I really like your comment because it summarizes the problems with my script really well. So, if you're cool with it--I'm pinning this comment.
      After this video I got a lot more fact checking support from my network, specifically my community over a the Biocord discord server. Maybe after I crack open my pchem textbook a few more times I'll dip back into videos like this--but definitely not for a while. There are enough proteins for me to write about without reaching too far into the fields I don't remember enough.

    • @trailblazer7702
      @trailblazer7702 2 года назад +1

      Chemistry of aqueous solutions! :DDDDD

    • @matejvidovic7859
      @matejvidovic7859 2 года назад +2

      Definitely the most detailed video on chemistry behind it on RUclips. Does anyone have suggestions as to where one should look to read on scientific papers on this topic. I'm doing a research project on Le Chatelier, equilibrium, pH...I need chemical equations regarding products and reactants, acids and bases, conjugate acids and conjugate bases...does anyone have a link with detailed info on this?

    • @daviddimbleby6725
      @daviddimbleby6725 Год назад

      Could you elaborate Morgan......

    • @BranTaliesyn
      @BranTaliesyn 5 месяцев назад

      The 'glorious clockwork' eh'? I can even see how one eyed ,color blind, and dead the lens you look at this living universe is from the PowerPoint thing. I kant even rn, Humen. ✌

  • @drpaul-dentist
    @drpaul-dentist 18 дней назад +15

    I am a dentist and stumbled upon this post. Let me say that you did a wonderful job. Like one of the other correspondence, I too grabbed a toothbrush and brushed my teeth after viewing this post. You did ask for corrections and clarifications which is most commendable and thus I assume you follow scientific principles of getting things right. I ran this by a dental materials PhD. Here is his assessment of your explanation: "Apart from it being somewhat inaccurate, the topic is well presented. Fluoride has an anti-cavity effect, and the epidemiological evidence is good. However nobody knows precisely how or why it works. The solubility differences mentioned in the post is minute (x0.6). Fluoroapatite is not formed - CaF2 is. The solubility ratio is constant over a large pH range, and there is NO switch point: it is an artifact of bad data plotting and analysis. Do it right and the illusion vanishes. Tooth mineral is not Hydroxyapatite, but a biological apatite with many important differences. Remineralization is not actually true.
    The fact is, it is an embarrassment to the folks that work on fluoride that they cannot explain the exact mechanism.
    However we do know with great certainty that fluoride does reduce tooth decay and is safe in therapeutic doses."
    Please note that I offer this as a constructive critique. I highly regard the manner with which you attempt to explain difficult and complex biological concepts in an understandable fashion for the lay public. Keep up the good work.

  • @janeenduff1589
    @janeenduff1589 3 года назад +64

    I am a retired dental hygiene educator. I am working on a presentation for nutrition students on oral health as it relates to cariology, dietary counseling and saliva testing. In preparation I've been viewing a lot of videos lately and THIS is short, to the point, simplified science and awesome for visual learners. Thank you so much!

    • @vaerner
      @vaerner Год назад +1

      Indeed. I loved the way this video conveyed the importance of balance

  • @philp1232
    @philp1232 4 года назад +29

    As a fellow biochemist, I love how you explain this stuff great job cant wait to see you make more!

  • @CKTCation
    @CKTCation 4 года назад +14

    This was so fascinating and the animation is really beautiful. Amazing video - can't wait to see your next one!

  • @miccecca
    @miccecca 3 года назад +26

    I’m glad you mention that over-fluoridated water can be toxic; while we know it to strengthen teeth, I‘d like to know more about what happens when it’s ingested.

    • @YahwehhasgivenaservanttoHis
      @YahwehhasgivenaservanttoHis 6 месяцев назад

      3years on…
      Taking the “drug” prescribed by municipal water districts (do they have a license to practice medicine…!) systemically (internally) affects only your teeth and has no impact whatsoever on your soft tissues organs or any other part of your body…
      Trust me, I am a scientist.
      Butcher…

    • @DASLAKILL
      @DASLAKILL 14 дней назад

      It's a neurotoxin and an adjuvant for other heavy metals. Half the fluoride ingested stays in your body building up.

  • @Annapolisz
    @Annapolisz 2 года назад +4

    Your modesty and sense of humor make this already fascinating video even more lovable.

  • @jesseyvanbeek3421
    @jesseyvanbeek3421 4 года назад +8

    Amazing video, this explanation makes a lot of sense and I like the message in the end. Looking forward to your next video!

  • @flyingsquirrelproductions2373
    @flyingsquirrelproductions2373 3 года назад +4

    Coming from a biochem grad student, this channel is awesome!! Keep up the great work!

  • @FrenkMelk
    @FrenkMelk Год назад +4

    so the exact mechanism of fluoride in tooth Health has been kind of an imponderable for me. this morning I finally decided to look on some RUclips videos for answers. I was very impressed with the angle you take and describing the processes and understanding that the limits of your personal knowledge are not bounded and open to review as well as editing from your peers. good job!

  • @bryanalexisleoncastillo316
    @bryanalexisleoncastillo316 4 года назад +4

    Gorgeous video, loved the final message

  • @svetlanacarver9020
    @svetlanacarver9020 3 года назад +1

    Amazing! Thanks for this video. It’s so easy to understand and learn about the different parts of the body. Can’t wait for your next video!! xx

  • @djt7387
    @djt7387 6 месяцев назад +1

    That was fun to listen to. Thank you for compounding knowledge.

  • @LongLiveTheDoors67
    @LongLiveTheDoors67 2 года назад +5

    This was a great video! I just got my first huge cavity a week ago--dentist appointment is next week--and so I've been on an education binge on what to do to help treat it. You are exactly right that most coverage of the effects of fluoride end at just saying "do it, it makes your teeth stronger". That infuriates me to no end! I wanted to know WHY it works, and your video did an excellent job of clearing it up. I truly appreciate the work you put in, I'll be subscribing for sure!

    • @safsult
      @safsult 8 месяцев назад

      I recently learned about xylitol ,after every meal or drink ,use a xylitol gum ,balls or pearls

  • @green0563
    @green0563 3 года назад +1

    Amazing. Subscribing a minute in, because this is just so good.

  • @RasmusKramerSchou
    @RasmusKramerSchou Год назад +2

    Banging video. Made me brush teeth instantly. Subbed

  • @grumpyuncle.
    @grumpyuncle. 5 месяцев назад +1

    Excellent content! Well done!

  • @kevinjiang6647
    @kevinjiang6647 4 года назад +73

    here before this channel becomes the next kurzgesagt ;)

    • @bmw_m4255
      @bmw_m4255 Год назад +6

      It didn't

    • @bintanglintangerlangga1983
      @bintanglintangerlangga1983 Год назад +5

      He stop making video 2 year ago so sadly it will never be the next kurzgesagt
      Edit: He is making a season 2 it might aswell be the next kurzgesagt

    • @pizzainc.1465
      @pizzainc.1465 26 дней назад +3

      Kurzgesagt, or less commonly known but technically still valid, “in a nutshell,” does not deal with biochemistry. So they could coexist. Also he may have ran out of topics, at which point he would need suggestions

    • @savethestick8609
      @savethestick8609 26 дней назад

      @@bmw_m4255it will

    • @savethestick8609
      @savethestick8609 26 дней назад +1

      @@bintanglintangerlangga1983he’s making a season 2 as views have increased 🎉🎉🎉🎉

  • @goldreserve
    @goldreserve 11 месяцев назад +2

    Earned a sub, great video.

  • @javokhir1556
    @javokhir1556 2 года назад +17

    Briefly about fluorine: the fluorine atom is small enough and has the highest electronegativity. As a result of the formation of bonds, the electron that took the fluorine is very close to the nucleus, and the screening effect is minimal. Therefore, it is much more difficult to expel fluorine from apatite than the hydroxyl group.

  • @bravebrush5057
    @bravebrush5057 3 года назад +1

    So good quality!

  • @RobiTheophilus
    @RobiTheophilus 3 года назад

    Love this. Thank you!

    • @Clockworkbio
      @Clockworkbio  3 года назад

      No--thank YOU for taking the time to reach out!

  • @WritersInkTHEWORD
    @WritersInkTHEWORD 11 месяцев назад

    very good just what I was looking for thankyou

  • @motherloverkiller
    @motherloverkiller 4 года назад +2

    This channel is finna blow up

  • @MrKAPESHKA
    @MrKAPESHKA 3 года назад

    great video!

  • @germaniumdiode
    @germaniumdiode Месяц назад

    Such an amazing show

  • @daviddimbleby6725
    @daviddimbleby6725 Год назад

    Thanks for the info ! 👍 your very humble dude it's refreshing ✌

  • @community1854
    @community1854 2 года назад +1

    This is gold

  • @RenayEmond
    @RenayEmond 3 года назад +12

    Great Channel!
    Can see why John Green gave this a recommendation
    Subscribed for more Awesome Learning 😁
    👏🏼✌🏽❤🙏🏽

  • @user-jn4ms6dd4s
    @user-jn4ms6dd4s Год назад +5

    I have a tooth that needs root canal and periodontal pockets. Every time I use fluoride toothpaste I get severe pain and inflammation, this doesn’t happen when using fluoride free toothpaste ever

    • @cosmolosys
      @cosmolosys 8 месяцев назад

      maybe you are allergic?

    • @protosfotod2416
      @protosfotod2416 20 дней назад

      Use your brain and put 2 and 2 together. Or listen to your body.

  • @timreagan777
    @timreagan777 2 года назад

    this video was fucking great! solid information and well spoken!

  • @mohammadahmad4972
    @mohammadahmad4972 2 года назад +3

    First of all thank you for this useful presentation I really enjoyed the chemistry part but around fluoride may cause damage or discolored your teeth it may cause that if someones receive excessive fluoride systematically during tooth development stages so excessive fluoride in your mouth do not cause discoloration unless you swallow it at time where tooth are in develop stage before they erupt

  • @alexaa8572
    @alexaa8572 Год назад +1

    as a dentist, this is amazing. well done

  • @user-xi3mk8kp4j
    @user-xi3mk8kp4j 5 месяцев назад

    thank you i learned alot from ur video .. would like to ask if u have topic related to fluorosis .. could u talk about it why we get the white yellow spot related to fluoride consumtion. thank u

  • @glebbeer4160
    @glebbeer4160 3 года назад +3

    Привет из Беларуси спасибо за это видео!

  • @AdityaPratapSingh-ss8wg
    @AdityaPratapSingh-ss8wg Год назад +1

    Wow awesome guy awesome script... Great

  • @nikitajouchims9584
    @nikitajouchims9584 4 года назад +1

    I use miswak never had toothpain since.

  • @teststream2511
    @teststream2511 3 года назад +1

    Hi from Vert Dider!

  • @santoshsahani4264
    @santoshsahani4264 10 месяцев назад +3

    Dental health is power💪

  • @graemelaubach3106
    @graemelaubach3106 Год назад

    Best biochem channel right now. Perfect animation, informative and just, so sexy. This will blow up soon.

  • @user-sh1tg4kb4o
    @user-sh1tg4kb4o 3 года назад +1

    A huge thanks to the person who shared this video on reddit

  • @BRAND0N...
    @BRAND0N... 17 дней назад +1

    Could you cite any research that indicates or proves that ingesting the specific type of fluoride that we drink in our tap water? Also why did you seem to imply that it's the same kind that's in our toothpaste?

  • @Jakensik
    @Jakensik 3 года назад

    What about streptococcus salivarius m18?

  • @wyla5896
    @wyla5896 Год назад +2

    Could other ions (strontium, chloride, heck- uranium theoretically) be used to replace the OH in apatite for an even more acid-resistant matrix than fluoride? Why don’t we use other ions besides fluoride?

    • @lolerie
      @lolerie Год назад +1

      Because we now know nano-mhap is much more safe and fast and nice than F.

    • @storyls
      @storyls 7 месяцев назад +1

      Because fluoride is the best.
      You can use chloride to make clorapatite but that is weaker than hydroxyapatite. Hypothetically you could use bromine or any other halogen too but that would be even worse.
      Fluorine is the most electronegative element in the periodic, it pulls together those ions because it really wants their electrons. That’s just it.

  • @MrKAPESHKA
    @MrKAPESHKA 3 года назад

    thnks from Kiev

  • @TheOgi22
    @TheOgi22 22 дня назад

    03:35 is posible to make this font smaller?
    :)

  • @ryanatkinson2978
    @ryanatkinson2978 28 дней назад

    Has this channel finally been blessed by the almighty algorithm? I hope he starts uploading again!

  • @ashleycarter1661
    @ashleycarter1661 3 года назад +3

    It bothers me how the woman is brushing her teeth incorrectly with that electric toothbrush!!

  • @user-yb4om7zd7b
    @user-yb4om7zd7b 3 года назад

    Так поддержал канал, осталось выучить английский. Спасибо vert dider за перевод

  • @adrianmoisa2281
    @adrianmoisa2281 2 года назад

    No more videos :( ?

  • @gx1501996
    @gx1501996 3 года назад

    Your website links say Website Expired

  • @Khmerstreets
    @Khmerstreets 25 дней назад

    I never brushed with toothpaste before, lol i guess i should start doing that

  • @seanm7553
    @seanm7553 Год назад +1

    U could have explained why stannous fluoride works so much better than sodium fluoride.

  • @igloozoo3771
    @igloozoo3771 10 месяцев назад +2

    So why not use Hydroxyapatite toothpaste instead of Fluoride?

    • @Nxck2440
      @Nxck2440 2 месяца назад +1

      Hydroxyapatite is a crystal, how are they going to put that in a tube?

    • @TS-jm7jm
      @TS-jm7jm 21 день назад

      ​@@Nxck2440grind it up into a fine powder and add it to the liquid mix

  • @lyhongleft3676
    @lyhongleft3676 3 дня назад

    What if you don't eat carbs and eat lets say, meat instead?

  • @mechez774
    @mechez774 24 дня назад

    I wonder if the fluoride has to be applied topically for fluorapatite formation, or whether there is also some mechanism whereby ingested fluoride is transported from the digestive system back to the mouth. It seems like this is part of the claim of water fluoridation advocates

    • @denofpigs2575
      @denofpigs2575 12 дней назад

      Water fluoridation has never been about improving your health.

  • @gaureearolkar1522
    @gaureearolkar1522 17 дней назад

    many yt vdo about whitening teeth using vinegar, baking soda, etc....
    wonder what damage they would cause to teeth?

  • @snowps1
    @snowps1 2 года назад +2

    Does fluoridated water turn your teeth yellow over time?

    • @lolieslover2179
      @lolieslover2179 2 года назад

      no the quantity of fluoride in both tape water and toothpaste have no harm on your teeth and your health

  • @silverlyder
    @silverlyder 8 месяцев назад

    6:20 me too I cant find a definitive answer

  • @jorge.tavares
    @jorge.tavares 17 дней назад

    naaaaaooo so tem 12 videos nesse canal 😭😭😭😭😭😭

  • @MrRaybrown007
    @MrRaybrown007 5 месяцев назад

    I wonder about fluoride in toothpaste, I feel just not eating sugary foods would be better.

  • @pab166
    @pab166 3 года назад

    From Vert Dider.

  • @nandavenki3913
    @nandavenki3913 4 года назад

    Are u a researcher?

  • @misty_jeera
    @misty_jeera 3 года назад

    Got here from a Corporis video : )

    • @Clockworkbio
      @Clockworkbio  3 года назад +1

      hell yea friend--thanks for letting me know! Hope this channel someday catches up to him in quality!

  • @Tomatos1234
    @Tomatos1234 Год назад +12

    A customer cured is a customer lost, just remember that.

    • @HUEHUEUHEPony
      @HUEHUEUHEPony 25 дней назад

      I'm not American, so this doesn't apply

  • @darnelljackson2160
    @darnelljackson2160 Год назад

    skip to 0:45 to get to the actual topic.

  • @Liineeeee
    @Liineeeee 19 дней назад

    my real question is not why fluorine is better but more why didnt our body already got fluorine there. Well I guess it doesnt like dealing with fluorine because fluorine is... a bit mean.

  • @PewDiePie777
    @PewDiePie777 Месяц назад

    Btw, if you ever wondered what video would be able to make your type of content blow up. In my experience, it would be something connected with reproducing. It's just a kind of trend I noticed in the most popular RUclips channels of this thematic. Just an observation.

  • @pyroromancer
    @pyroromancer 2 года назад

    _interlinked_
    *within cells interlinked within cells interlinked within cells interlinked*

  • @AJ-rd4ng
    @AJ-rd4ng Месяц назад

    Iiiiiirons iiiiiirons iiiiiirons ⚒️⚒️⚒️

  • @stratfilovski6539
    @stratfilovski6539 3 года назад

    спасибо за полезную информацию. подача отличная! привет из России))

  • @imveryhungry112
    @imveryhungry112 Месяц назад

    Is flouride good for my teeth or not please just someone answer and help me

    • @macon8638
      @macon8638 Месяц назад

      Yeah it’s good for you’re teeth 🙃 Like everything it’s good in moderation, most places in the world don’t have too much fluoride

    • @DASLAKILL
      @DASLAKILL 14 дней назад

      Fluoride is a neurotoxin, and a waste product of heavy industry. None of it in any quantity is good for you.

  • @yerassylmukhamediyar4818
    @yerassylmukhamediyar4818 3 года назад +1

    Hello from Kazakhstan. Good lack to your channel

  • @1337bitcoin
    @1337bitcoin 19 дней назад +1

    2024 comeback???

  • @wayneeligur7586
    @wayneeligur7586 10 дней назад

    Only Calcium Fluoride strengthens and protects teeth not the industrial version Sodium Fluoride!
    There is no safe minimum dose of elemental Fluoride!
    I suggest redoing the video after more research.

  • @myceliation
    @myceliation 24 дня назад

    fluorapatite causes differential erosion of teeth which then further quickly erodes the hydroxyapatite sections of your mouth

  • @Gunzee
    @Gunzee 4 года назад +1

    Drink carbonated things, even water through a straw & chew gum often.

  • @BlownMacTruck
    @BlownMacTruck Месяц назад +1

    6:21 for someone who supposedly loves learning, please learn how to use “begs the question” correctly. It’s a huge red flag when people who are trying to convey information use this phrase in a completely inapplicable way.

    • @makego
      @makego 28 дней назад

      It has more than one definition. It's not just the rhetorical fallacy. From the OED: 1. (of a fact or action) raise a question or point that has not been dealt with; invite an obvious question.

    • @BlownMacTruck
      @BlownMacTruck 28 дней назад

      @@makego Cite your reference.

  • @JewsRock-ILJ
    @JewsRock-ILJ 25 дней назад +2

    The fluoride will make the dentin in the tooth become brittle and will make it easier to snap the tooth. If you stop consuming sugar and high levels of carbs you won't have to worry about the acid from bacteria decaying the teeth. A good alternative for tooth paste is pure olive oil soap, flossing, hydrogen peroxide, mouthwash, and 40-75% ethanol right after consuming food.

    • @denofpigs2575
      @denofpigs2575 12 дней назад

      I use a homemade toothpaste of coconut oil, hydrogen peroxide, baking soda, and clove oil. Stuff makes my teeth feel pristine.