Carnitine Shuttle | Purpose and Mechanism

Lesson on the Carnitine Shuttle. Carnitine is an important metabolite derived from our diet or biosynthesized from lysine and methionine. Since the mitochondrial inner membrane is impermeable to long chain fatty acids, carnitine is used as a shuttle molecule (a carrier system) to transport long chain fatty acids into the mitochondrial matrix for beta oxidation. Once carnitine has shuttled the fatty acyl chain into the mitochondrial matrix, carnitine can be regenerated and transported back out into the cytosol to be used again for fatty acid transport.
I hope you find this video helpful. If you do, please like and subscribe (make sure to turn on the bell for notifications) for more videos like this one :)
Subscribe for more free medical lessons / @jjmedicine
-------------------------------------------------------------------------------------------------------------
For books and more information on these topics
www.amazon.com...
Support future lessons (and get other cool stuff) ➜ / jjmedicine
Follow me on Twitter! ➜ / jj_medicine
Come join me on Facebook! ➜ / jj-medicine-1006426481...
Start your own website with BlueHost ➜ www.bluehost.c...
Check out the best tool to help grow your RUclips channel (it’s helped me!)
www.tubebuddy....
-------------------------------------------------------------------------------------------------------------
Check out some of my other lessons.
Medical Terminology - The Basics - Lesson 1:
• Medical Terminology - ...
Fatty Acid Synthesis Pathway:
• Fatty Acid Synthesis P...
Wnt/B Catenin Signaling Pathway:
• Wnt/β-Catenin Signalin...
Upper vs. Lower Motor Neuron Lesions:
• Upper and Lower Motor ...
Lesson on the Purine Synthesis and Salvage Pathway:
• Purine Synthesis and S...
Gastrulation | Formation of Germ Layers:
• Gastrulation | Formati...
Introductory lesson on Autophagy (Macroautophagy):
• Autophagy | Macroautop...
Infectious Disease Playlist
• Infectious Diseases
Dermatology Playlist
• Dermatology
Pharmacology Playlist
• Pharmacology
Hematology Playlist
• Hematology
Rheumatology Playlist
• Rheumatology
Endocrinology Playlist
• Endocrinology
Nephrology Playlist
• Nephrology
----------------------------------------------------------------------------------------------------
**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.
Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.
----------------------------------------------------------------------------------------------------
Although I try my best to present accurate information, there may be mistakes in this video. If you do see any mistakes with information in this lesson, please comment and let me know.
I am always looking for ways to improve my lessons! Please don't hesitate to leave me feedback and comments - all of your feedback is greatly appreciated! :) And please don't hesitate to send me any messages if you need any help - I will try my best to be here to help you guys :)
Thanks for watching! If you found this video helpful, please like and subscribe!
JJ

[@StormsRadiosCats]

I am a patient with CPT2, - Levo Carnitine in a large does daily is the way I supplement since my liver does not create Carnitine on it's own.
This video is very helpful, I was diagnosed when I was 21 yrs. old and I am 55 now, CPT2 has been a challenge.

[@cherryblossem4]

super helpful! so glad I took the time to look this up instead of trying to read this over and over again (cause I still wouldn't get it)

[@eduardozamora2182]

Great explanation. Clear graphics. Thank you sir. Very helpful. 👏

[@EsotericMedic]

This made it so much clearer, thank you!

[@onso]

It was great, sharp, clear and very knowledgeably
Thank you for the video.

[@victoriaezembu4509]

Thank you so much for this simple explanation!!❤

[@tiffanyvelasquez4062]

Life saver!! This is a perfect explanation. Thank you!

[@mengyueyang9421]

thank you, sir. this is super helpful !!!

[@zionoluwasegun]

Exactly what I was looking for. Thanks 👌

[@jennaduzs3821]

really great video!! thank you !

[@gavinnichols8277]

Most other sources say that fatty acyl-coa can pass UNAIDED into the intermembrane space, where they are acted upon by CPT1 in order to cross the INNER mitocondrial membrane. Comments?

[@jacobshawn5547]

I am 99% sure that you are correct. This explanation drove me crazy for the last 20 mins

[@zas881]

THANK YOU!

[@rihamesper8758]

best guy on youtube

[@1rrrrrrrrrrr544f]

Thanks a million ❤❤❤❤

[@p3tr_jr]

Really helpful 👌

[@amandahamel5638]

really good visual

[@maheen97]

thank you!!

[@fhksr184]

Long chain means longer than 12 C fatty acids i think

[@DanScottChannel]

Could a deficiency in carnitine cause ones HDL to go sky high after going on a low carb/high fat "ketogenic" diet?

[@saraalkhaledi1178]

Thank youuuuu

[@harshk7519]

But cpt1 is present on inner mitochondrial membrane

[@sarah_muwafaq]

🌸🌸

[@spreadpositivity-mg4em]

1:35🫠