Needle is the term used to describe the bladed weapon wielded by Hornet. The needle is attached with a thread of silk.Figment of an obsessed mind. Lacks grace but becomes stronger with every defeat. "My love, any creature who could bear to be away from you, who would willingly leave you behind or say unkind things to you... Pah! Lowly maggots, not worthy of standing in your glorious shadow!" She felt her cold body grow warm, a sensation she had almost forgotten... - 'The Grey Prince' Chapter 112 Shardmites are enemies in Hollow Knight. Formerly used in Crystal Peak's mining operations, these creatures now wander around on walls, feeding on crystal dust. Crawls up and down on vertical surfaces. Upon approaching it, it sprouts long crystal spikes from its shell. While those spikes are extended, it is invulnerable. By attacking quickly, it can be taken off guard and killed before it sprouts its spikes. It is also possible to Nail-bounce off its spikes by down-slashing. With repeated down-slashing, the Shardmite retracts its spikes briefly before sprouting them again, giving the Knight a chance to get in a hit between spikes while keeping distance. Grey Prince Zote is a hidden boss in Hollow Knight introduced in the Hidden Dreams update. He is the stronger Dream variant of Zote the Mighty, fueled by Bretta's fantasies of him. Behaviour and Tactics Flail: Grey Prince Zote charges at the Knight, flailing his nail before him. Grey Prince Zote flails his nail for 2-4 seconds. Once he is exhausted, he falls to the ground, sending out a shockwave in each direction. While he is flailing, he moves with momentum, as if he were on ice. There is a variation to this attack where Grey Prince Zote prepares to flail, only to fall over, sending out the shockwaves immediately. Zotelings Spit: Grey Prince Zote spits out Zotelings that attack the Knight independently of Grey Prince Zote. The first Zoteling Grey Prince Zote can spit is the Winged Zoteling. These Zotelings can show up with any version of Grey Prince Zote. The other Zoteling Grey Prince Zote can spit is the Hopping Zoteling. These Zotelings do not show up until Zote 2 and later. Grey Prince Zote spits out one to three Zotelings in rapid succession per attack. The Zotelings deal half of the damage scaled with each version of Grey Prince Zote on rounding down to a minimum of 1. These Zotelings remain in the arena until they are killed. Shadow Slam: Grey Prince Zote leaps into the air, and as he lands, he transmutes into a pillar of shadows, launching himself high above the arena. Moments later, he slams down, sending two large shockwaves across the arena in opposite directions. Grey Prince Zote lands where he believes the Knight is going to be rather than where the Knight was. Grey Prince Zote can link into this attack after a Leap attack. Nail Slam: Grey Prince Zote leaps into the air and slams his nail down. This attack targets the Knight. Grey Prince Zote slams his nail down where the Knight is when he reaches the apex of his leap, just before he flips. When he slams his nail, two shockwaves erupt from the impact point and travel across the arena. The one in front of Grey Prince Zote is larger than the one travelling behind him. There is a variation to this attack which involves Grey Prince Zote reaching the apex of his leap, and instead of slamming down then, pirouetting in the air to readjust his targeting, and then slamming down. Leap: Grey Prince Zote leaps around the arena. Grey Prince Zote can string together up to three Leaps in a row. He can also chain this attack into a Shadow Slam attack. Every time Grey Prince Zote lands, he sends out two small shockwaves in either direction that cross the arena. Summon Bombs: Grey Prince Zote cries out and summons 3-4 Volatile Zotelings around the arena, which explode after a short time or when killed (note that unlike other explosive enemies in the game, the explosions cannot deal damage to Grey Prince Zote). This attack happens in his 3rd fight and later. The Volatile Zotelings spawn anywhere in the air with room for them. Like the other summon attack, the Volatile Zotelings can persist while Grey Prince Zote uses other attacks, though only briefly as they self-destruct. Unlike the other summoned types of Zotelings in the fight, the damage from the Volatile Zotelings and their explosions (base 1 Mask) do scale with each victory. Stagger Values Description: Grey Prince Zote falls onto his back, flailing about. Hits: 17/18/19 in fights 1/2/3+ Combo: 14/15/16 in fights 1/2/3+ Combo Time:
Behaviour and Tactics Flail: Grey Prince Zote charges at the Knight, flailing his nail before him. Grey Prince Zote flails his nail for 2-4 seconds. Once he is exhausted, he falls to the ground, sending out a shockwave in each direction. While he is flailing, he moves with momentum, as if he were on ice. There is a variation to this attack where Grey Prince Zote prepares to flail, only to fall over, sending out the shockwaves immediately. Zotelings Spit: Grey Prince Zote spits out Zotelings that attack the Knight independently of Grey Prince Zote. The first Zoteling Grey Prince Zote can spit is the Winged Zoteling. These Zotelings can show up with any version of Grey Prince Zote. The other Zoteling Grey Prince Zote can spit is the Hopping Zoteling. These Zotelings do not show up until Zote 2 and later. Grey Prince Zote spits out one to three Zotelings in rapid succession per attack. The Zotelings deal half of the damage scaled with each version of Grey Prince Zote on rounding down to a minimum of 1. These Zotelings remain in the arena until they are killed. Shadow Slam: Grey Prince Zote leaps into the air, and as he lands, he transmutes into a pillar of shadows, launching himself high above the arena. Moments later, he slams down, sending two large shockwaves across the arena in opposite directions. Grey Prince Zote lands where he believes the Knight is going to be rather than where the Knight was. Grey Prince Zote can link into this attack after a Leap attack. Nail Slam: Grey Prince Zote leaps into the air and slams his nail down. This attack targets the Knight. Grey Prince Zote slams his nail down where the Knight is when he reaches the apex of his leap, just before he flips. When he slams his nail, two shockwaves erupt from the impact point and travel across the arena. The one in front of Grey Prince Zote is larger than the one travelling behind him. There is a variation to this attack which involves Grey Prince Zote reaching the apex of his leap, and instead of slamming down then, pirouetting in the air to readjust his targeting, and then slamming down. Leap: Grey Prince Zote leaps around the arena. Grey Prince Zote can string together up to three Leaps in a row. He can also chain this attack into a Shadow Slam attack. Every time Grey Prince Zote lands, he sends out two small shockwaves in either direction that cross the arena. Summon Bombs: Grey Prince Zote cries out and summons 3-4 Volatile Zotelings around the arena, which explode after a short time or when killed (note that unlike other explosive enemies in the game, the explosions cannot deal damage to Grey Prince Zote). This attack happens in his 3rd fight and later. The Volatile Zotelings spawn anywhere in the air with room for them. Like the other summon attack, the Volatile Zotelings can persist while Grey Prince Zote uses other attacks, though only briefly as they self-destruct. Unlike the other summoned types of Zotelings in the fight, the damage from the Volatile Zotelings and their explosions (base 1 Mask) do scale with each victory.
About half of those diagnosed with schizophrenia will have a significant improvement over the long term with no further relapses, and a small proportion of these will recover completely.[9][22] The other half will have a lifelong impairment.[23] In severe cases, people may be admitted to hospitals.[22] Social problems such as long-term unemployment, poverty, homelessness, exploitation and victimization are commonly correlated with schizophrenia.[24][25] Compared to the general population, people with schizophrenia have a higher suicide rate (about 5% overall) and more physical health problems,[26][27] leading to an average decrease in life expectancy by 20[12] to 28 years.[13] In 2015, an estimated 17,000 deaths were linked to schizophrenia.[15]
Cognitive symptoms See also: Visual processing abnormalities in schizophrenia Map of deficits in neural tissue throughout the human brain in a patient with schizophrenia. The most deficient areas are magenta, while the least deficient areas are blue. An estimated 70% of those with schizophrenia have cognitive deficits, and these are most pronounced in early onset and late-onset illness.[53][54] These are often evident long before the onset of illness in the prodromal stage, and may be present in childhood or early adolescence.[55][56] They are a core feature but not considered to be core symptoms, as are positive and negative symptoms.[57][58] However, their presence and degree of dysfunction is taken as a better indicator of functionality than the presentation of core symptoms.[55] Cognitive deficits become worse at first episode psychosis but then return to baseline, and remain fairly stable over the course of the illness.[59][60]
he deficits in cognition are seen to drive the negative psychosocial outcome in schizophrenia, and are claimed[who?] to equate to a possible reduction in IQ from the norm of 100 to 70-85.[61][62] Cognitive deficits may be of neurocognition (nonsocial) or of social cognition.[53] Neurocognition is the ability to receive and remember information, and includes verbal fluency, memory, reasoning, problem solving, speed of processing, and auditory and visual perception.[60] Verbal memory and attention are seen to be the most affected.[62][63] Verbal memory impairment is associated with a decreased level of semantic processing (relating meaning to words).[64] Another memory impairment is that of episodic memory.[65] An impairment in visual perception that is consistently found in schizophrenia is that of visual backward masking.[60] Visual processing impairments include an inability to perceive complex visual illusions.[66] Social cognition is concerned with the mental operations needed to interpret, and understand the self and others in the social world.[60][53] This is also an associated impairment, and facial emotion perception is often found to be difficult.[67][68] Facial perception is critical for ordinary social interaction.[69] Cognitive impairments do not usually respond to antipsychotics, and there are a number of interventions that are used to try to improve them; cognitive remediation therapy is of particular help.[58]
Risk factors Main article: Risk factors of schizophrenia Schizophrenia is described as a neurodevelopmental disorder with no precise boundary, or single cause, and is thought to develop from gene-environment interactions with involved vulnerability factors.[6][78][79] The interactions of these risk factors are complex, as numerous and diverse insults from conception to adulthood can be involved.[79] A genetic predisposition on its own, without interacting environmental factors, will not give rise to the development of schizophrenia.[79][80] The genetic component means that prenatal brain development is disturbed, and environmental influence affects the postnatal development of the brain.[81] Evidence suggests that genetically susceptible children are more likely to be vulnerable to the effects of environmental risk factors.[81] Genetic Estimates of the heritability of schizophrenia are between 70% and 80%, which implies that 70% to 80% of the individual differences in risk of schizophrenia are associated with genetics.[20][82] These estimates vary because of the difficulty in separating genetic and environmental influences, and their accuracy has been queried.[83][84] The greatest risk factor for developing schizophrenia is having a first-degree relative with the disease (risk is 6.5%); more than 40% of identical twins of those with schizophrenia are also affected.[85] If one parent is affected the risk is about 13% and if both are affected the risk is nearly 50%.[82] However, the DSM-5 indicates that most people with schizophrenia have no family history of psychosis.[9] Results of candidate gene studies of schizophrenia have generally failed to find consistent associations,[86] and the genetic loci identified by genome-wide association studies explain only a small fraction of the variation in the disease.[87] Many genes are known to be involved in schizophrenia, each with small effects and unknown transmission and expression.[20][88][89] The summation of these effect sizes into a polygenic risk score can explain at least 7% of the variability in liability for schizophrenia.[90] Around 5% of cases of schizophrenia are understood to be at least partially attributable to rare copy number variations (CNVs); these structural variations are associated with known genomic disorders involving deletions at 22q11.2 (DiGeorge syndrome) and 17q12 (17q12 microdeletion syndrome), duplications at 16p11.2 (most frequently found) and deletions at 15q11.2 (Burnside-Butler syndrome).[91] Some of these CNVs increase the risk of developing schizophrenia by as much as 20-fold, and are frequently comorbid with autism and intellectual disabilities.[91] The genes CRHR1 and CRHBP are associated with the severity of suicidal behavior. These genes code for stress response proteins needed in the control of the HPA axis, and their interaction can affect this axis. Response to stress can cause lasting changes in the function of the HPA axis possibly disrupting the negative feedback mechanism, homeostasis, and the regulation of emotion leading to altered behaviors.[80] The question of how schizophrenia could be primarily genetically influenced, given that people with schizophrenia have lower fertility rates, is a paradox. It is expected that genetic variants that increase the risk of schizophrenia would be selected against, due to their negative effects on reproductive fitness. A number of potential explanations have been proposed, including that alleles associated with schizophrenia risk confers a fitness advantage in unaffected individuals.[92][93] While some evidence has not supported this idea,[84] others propose that a large number of alleles each contributing a small amount can persist.[94] A meta-analysis found that oxidative DNA damage was significantly increased in schizophrenia.[95]
About 0.3% to 0.7% of people are diagnosed with schizophrenia during their lifetime.[18] In 2017, there were an estimated 1.1 million new cases and in 2022 a total of 24 million cases globally.[2][19] Males are more often affected and on average have an earlier onset than females.[2] The causes of schizophrenia may include genetic and environmental factors.[6] Genetic factors include a variety of common and rare genetic variants.[20] Possible environmental factors include being raised in a city, childhood adversity, cannabis use during adolescence, infections, the age of a person's mother or father, and poor nutrition during pregnancy.[6][21]
Schizophrenia is a mental disorder[16] characterized by reoccurring episodes of psychosis that are correlated with a general misperception of reality.[6] Other common signs include hallucinations (typically hearing voices), delusions (i.e., paranoia), disorganized thinking,[9] social withdrawal, and flat affect.[6] Symptoms develop gradually and typically begin during young adulthood and are never resolved.[3][9] There is no objective diagnostic test; diagnosis is based on observed behavior, a psychiatric history that includes the person's reported experiences, and reports of others familiar with the person.[9] For a diagnosis of schizophrenia, the described symptoms need to have been present for at least six months (according to the DSM-5) or one month (according to the ICD-11).[9][17]
1:42:45 NOW PLAYING The Top 50 HARDEST Extreme Demons in Geometry Dash. fnm04 49K views 2 days ago New 1:42:45 NOW PLAYING The Top 50 HARDEST Extreme Demons in Geometry Dash. fnm04 49K views 2 days ago New
Location in Dirtmouth Location in Dirtmouth Gallery Flail attack Flail attack Nail Slam attack Nail Slam attack Shadow Slam attack Shadow Slam attack Bretta's basement with Zote's statue Bretta's basement with Zote's statue Zote's statue turned gold Zote's statue turned gold Arena in Bretta's dream Arena in Bretta's dream Arena in Godhome Arena in Godhome Grey Prince Zote Radiant (Hitless) Hollow Knight Grey Prince Zote Radiant (Hitless) Hollow Knight Achievements Achievement Dark Romance {S} Dark Romance Defeat Grey Prince Zote. 10G
Signs and symptoms My Eyes at the Moment of the Apparitions by German artist August Natterer, who had schizophrenia Schizophrenia is a mental disorder characterized by significant alterations in perception, thoughts, mood and behavior.[33] Symptoms are described in terms of positive, negative and cognitive symptoms.[3][34] The positive symptoms of schizophrenia are the same for any psychosis and are sometimes referred to as psychotic symptoms. These may be present in any of the different psychoses and are often transient, making early diagnosis of schizophrenia problematic. Psychosis noted for the first time in a person who is later diagnosed with schizophrenia is referred to as a first-episode psychosis (FEP).[35][36] Positive symptoms Positive symptoms are those symptoms that are not normally experienced, but are present in people during a psychotic episode in schizophrenia. They include delusions, hallucinations, and disorganized thoughts and speech, typically regarded as manifestations of psychosis.[35] Hallucinations occur at some point in the lifetimes of 80% of those with schizophrenia[37] and most commonly involve the sense of hearing (most often hearing voices), but can sometimes involve any of the other senses of taste, sight, smell and touch.[38] The frequency of hallucinations involving multiple senses is double the rate of those involving only one sense.[37] They are also typically related to the content of the delusional theme.[39] Delusions are bizarre or persecutory in nature. Distortions of self-experience such as feeling that others can hear one's thoughts or that thoughts are being inserted into one's mind, sometimes termed passivity phenomena, are also common.[40] Thought disorders can include thought blocking and disorganized speech.[3] Positive symptoms generally respond well to medication[6] and become reduced over the course of the illness, perhaps linked to the age-related decline in dopamine activity.[9]
painfully slow: the level
fr
Invincible Fearless Sensual Mysterious Enchanting Vigorous Diligent Overwhelming Gorgeous Passionate Terrifying Beautiful Powerful GREY PRINCE ZOTE!
HE IS THE BEST!
Needle is the term used to describe the bladed weapon wielded by Hornet. The needle is attached with a thread of silk.Figment of an obsessed mind. Lacks grace but becomes stronger with every defeat.
"My love, any creature who could bear to be away from you, who would willingly leave you behind or say unkind things to you... Pah! Lowly maggots, not worthy of standing in your glorious shadow!"
She felt her cold body grow warm, a sensation she had almost forgotten...
- 'The Grey Prince' Chapter 112
Shardmites are enemies in Hollow Knight. Formerly used in Crystal Peak's mining operations, these creatures now wander around on walls, feeding on crystal dust. Crawls up and down on vertical surfaces. Upon approaching it, it sprouts long crystal spikes from its shell. While those spikes are extended, it is invulnerable. By attacking quickly, it can be taken off guard and killed before it sprouts its spikes. It is also possible to Nail-bounce off its spikes by down-slashing. With repeated down-slashing, the Shardmite retracts its spikes briefly before sprouting them again, giving the Knight a chance to get in a hit between spikes while keeping distance.
Grey Prince Zote is a hidden boss in Hollow Knight introduced in the Hidden Dreams update. He is the stronger Dream variant of Zote the Mighty, fueled by Bretta's fantasies of him.
Behaviour and Tactics
Flail: Grey Prince Zote charges at the Knight, flailing his nail before him. Grey Prince Zote flails his nail for 2-4 seconds. Once he is exhausted, he falls to the ground, sending out a shockwave in each direction. While he is flailing, he moves with momentum, as if he were on ice. There is a variation to this attack where Grey Prince Zote prepares to flail, only to fall over, sending out the shockwaves immediately.
Zotelings Spit: Grey Prince Zote spits out Zotelings that attack the Knight independently of Grey Prince Zote. The first Zoteling Grey Prince Zote can spit is the Winged Zoteling. These Zotelings can show up with any version of Grey Prince Zote. The other Zoteling Grey Prince Zote can spit is the Hopping Zoteling. These Zotelings do not show up until Zote 2 and later. Grey Prince Zote spits out one to three Zotelings in rapid succession per attack. The Zotelings deal half of the damage scaled with each version of Grey Prince Zote on rounding down to a minimum of 1. These Zotelings remain in the arena until they are killed.
Shadow Slam: Grey Prince Zote leaps into the air, and as he lands, he transmutes into a pillar of shadows, launching himself high above the arena. Moments later, he slams down, sending two large shockwaves across the arena in opposite directions. Grey Prince Zote lands where he believes the Knight is going to be rather than where the Knight was. Grey Prince Zote can link into this attack after a Leap attack.
Nail Slam: Grey Prince Zote leaps into the air and slams his nail down. This attack targets the Knight. Grey Prince Zote slams his nail down where the Knight is when he reaches the apex of his leap, just before he flips. When he slams his nail, two shockwaves erupt from the impact point and travel across the arena. The one in front of Grey Prince Zote is larger than the one travelling behind him. There is a variation to this attack which involves Grey Prince Zote reaching the apex of his leap, and instead of slamming down then, pirouetting in the air to readjust his targeting, and then slamming down.
Leap: Grey Prince Zote leaps around the arena. Grey Prince Zote can string together up to three Leaps in a row. He can also chain this attack into a Shadow Slam attack. Every time Grey Prince Zote lands, he sends out two small shockwaves in either direction that cross the arena.
Summon Bombs: Grey Prince Zote cries out and summons 3-4 Volatile Zotelings around the arena, which explode after a short time or when killed (note that unlike other explosive enemies in the game, the explosions cannot deal damage to Grey Prince Zote). This attack happens in his 3rd fight and later. The Volatile Zotelings spawn anywhere in the air with room for them. Like the other summon attack, the Volatile Zotelings can persist while Grey Prince Zote uses other attacks, though only briefly as they self-destruct. Unlike the other summoned types of Zotelings in the fight, the damage from the Volatile Zotelings and their explosions (base 1 Mask) do scale with each victory.
Stagger Values
Description: Grey Prince Zote falls onto his back, flailing about.
Hits: 17/18/19 in fights 1/2/3+
Combo: 14/15/16 in fights 1/2/3+ Combo Time:
Behaviour and Tactics
Flail: Grey Prince Zote charges at the Knight, flailing his nail before him. Grey Prince Zote flails his nail for 2-4 seconds. Once he is exhausted, he falls to the ground, sending out a shockwave in each direction. While he is flailing, he moves with momentum, as if he were on ice. There is a variation to this attack where Grey Prince Zote prepares to flail, only to fall over, sending out the shockwaves immediately.
Zotelings Spit: Grey Prince Zote spits out Zotelings that attack the Knight independently of Grey Prince Zote. The first Zoteling Grey Prince Zote can spit is the Winged Zoteling. These Zotelings can show up with any version of Grey Prince Zote. The other Zoteling Grey Prince Zote can spit is the Hopping Zoteling. These Zotelings do not show up until Zote 2 and later. Grey Prince Zote spits out one to three Zotelings in rapid succession per attack. The Zotelings deal half of the damage scaled with each version of Grey Prince Zote on rounding down to a minimum of 1. These Zotelings remain in the arena until they are killed.
Shadow Slam: Grey Prince Zote leaps into the air, and as he lands, he transmutes into a pillar of shadows, launching himself high above the arena. Moments later, he slams down, sending two large shockwaves across the arena in opposite directions. Grey Prince Zote lands where he believes the Knight is going to be rather than where the Knight was. Grey Prince Zote can link into this attack after a Leap attack.
Nail Slam: Grey Prince Zote leaps into the air and slams his nail down. This attack targets the Knight. Grey Prince Zote slams his nail down where the Knight is when he reaches the apex of his leap, just before he flips. When he slams his nail, two shockwaves erupt from the impact point and travel across the arena. The one in front of Grey Prince Zote is larger than the one travelling behind him. There is a variation to this attack which involves Grey Prince Zote reaching the apex of his leap, and instead of slamming down then, pirouetting in the air to readjust his targeting, and then slamming down.
Leap: Grey Prince Zote leaps around the arena. Grey Prince Zote can string together up to three Leaps in a row. He can also chain this attack into a Shadow Slam attack. Every time Grey Prince Zote lands, he sends out two small shockwaves in either direction that cross the arena.
Summon Bombs: Grey Prince Zote cries out and summons 3-4 Volatile Zotelings around the arena, which explode after a short time or when killed (note that unlike other explosive enemies in the game, the explosions cannot deal damage to Grey Prince Zote). This attack happens in his 3rd fight and later. The Volatile Zotelings spawn anywhere in the air with room for them. Like the other summon attack, the Volatile Zotelings can persist while Grey Prince Zote uses other attacks, though only briefly as they self-destruct. Unlike the other summoned types of Zotelings in the fight, the damage from the Volatile Zotelings and their explosions (base 1 Mask) do scale with each victory.
nightt mar kingg grimmmmmmm
About half of those diagnosed with schizophrenia will have a significant improvement over the long term with no further relapses, and a small proportion of these will recover completely.[9][22] The other half will have a lifelong impairment.[23] In severe cases, people may be admitted to hospitals.[22] Social problems such as long-term unemployment, poverty, homelessness, exploitation and victimization are commonly correlated with schizophrenia.[24][25] Compared to the general population, people with schizophrenia have a higher suicide rate (about 5% overall) and more physical health problems,[26][27] leading to an average decrease in life expectancy by 20[12] to 28 years.[13] In 2015, an estimated 17,000 deaths were linked to schizophrenia.[15]
ZOTAAAAA
ITS COOL!
Gaming is cool frfr
hollow knight alert
Cognitive symptoms
See also: Visual processing abnormalities in schizophrenia
Map of deficits in neural tissue throughout the human brain in a patient with schizophrenia. The most deficient areas are magenta, while the least deficient areas are blue.
An estimated 70% of those with schizophrenia have cognitive deficits, and these are most pronounced in early onset and late-onset illness.[53][54] These are often evident long before the onset of illness in the prodromal stage, and may be present in childhood or early adolescence.[55][56] They are a core feature but not considered to be core symptoms, as are positive and negative symptoms.[57][58] However, their presence and degree of dysfunction is taken as a better indicator of functionality than the presentation of core symptoms.[55] Cognitive deficits become worse at first episode psychosis but then return to baseline, and remain fairly stable over the course of the illness.[59][60]
grey prince zote is cool
he deficits in cognition are seen to drive the negative psychosocial outcome in schizophrenia, and are claimed[who?] to equate to a possible reduction in IQ from the norm of 100 to 70-85.[61][62] Cognitive deficits may be of neurocognition (nonsocial) or of social cognition.[53] Neurocognition is the ability to receive and remember information, and includes verbal fluency, memory, reasoning, problem solving, speed of processing, and auditory and visual perception.[60] Verbal memory and attention are seen to be the most affected.[62][63] Verbal memory impairment is associated with a decreased level of semantic processing (relating meaning to words).[64] Another memory impairment is that of episodic memory.[65] An impairment in visual perception that is consistently found in schizophrenia is that of visual backward masking.[60] Visual processing impairments include an inability to perceive complex visual illusions.[66] Social cognition is concerned with the mental operations needed to interpret, and understand the self and others in the social world.[60][53] This is also an associated impairment, and facial emotion perception is often found to be difficult.[67][68] Facial perception is critical for ordinary social interaction.[69] Cognitive impairments do not usually respond to antipsychotics, and there are a number of interventions that are used to try to improve them; cognitive remediation therapy is of particular help.[58]
Risk factors
Main article: Risk factors of schizophrenia
Schizophrenia is described as a neurodevelopmental disorder with no precise boundary, or single cause, and is thought to develop from gene-environment interactions with involved vulnerability factors.[6][78][79] The interactions of these risk factors are complex, as numerous and diverse insults from conception to adulthood can be involved.[79] A genetic predisposition on its own, without interacting environmental factors, will not give rise to the development of schizophrenia.[79][80] The genetic component means that prenatal brain development is disturbed, and environmental influence affects the postnatal development of the brain.[81] Evidence suggests that genetically susceptible children are more likely to be vulnerable to the effects of environmental risk factors.[81]
Genetic
Estimates of the heritability of schizophrenia are between 70% and 80%, which implies that 70% to 80% of the individual differences in risk of schizophrenia are associated with genetics.[20][82] These estimates vary because of the difficulty in separating genetic and environmental influences, and their accuracy has been queried.[83][84] The greatest risk factor for developing schizophrenia is having a first-degree relative with the disease (risk is 6.5%); more than 40% of identical twins of those with schizophrenia are also affected.[85] If one parent is affected the risk is about 13% and if both are affected the risk is nearly 50%.[82] However, the DSM-5 indicates that most people with schizophrenia have no family history of psychosis.[9] Results of candidate gene studies of schizophrenia have generally failed to find consistent associations,[86] and the genetic loci identified by genome-wide association studies explain only a small fraction of the variation in the disease.[87]
Many genes are known to be involved in schizophrenia, each with small effects and unknown transmission and expression.[20][88][89] The summation of these effect sizes into a polygenic risk score can explain at least 7% of the variability in liability for schizophrenia.[90] Around 5% of cases of schizophrenia are understood to be at least partially attributable to rare copy number variations (CNVs); these structural variations are associated with known genomic disorders involving deletions at 22q11.2 (DiGeorge syndrome) and 17q12 (17q12 microdeletion syndrome), duplications at 16p11.2 (most frequently found) and deletions at 15q11.2 (Burnside-Butler syndrome).[91] Some of these CNVs increase the risk of developing schizophrenia by as much as 20-fold, and are frequently comorbid with autism and intellectual disabilities.[91]
The genes CRHR1 and CRHBP are associated with the severity of suicidal behavior. These genes code for stress response proteins needed in the control of the HPA axis, and their interaction can affect this axis. Response to stress can cause lasting changes in the function of the HPA axis possibly disrupting the negative feedback mechanism, homeostasis, and the regulation of emotion leading to altered behaviors.[80]
The question of how schizophrenia could be primarily genetically influenced, given that people with schizophrenia have lower fertility rates, is a paradox. It is expected that genetic variants that increase the risk of schizophrenia would be selected against, due to their negative effects on reproductive fitness. A number of potential explanations have been proposed, including that alleles associated with schizophrenia risk confers a fitness advantage in unaffected individuals.[92][93] While some evidence has not supported this idea,[84] others propose that a large number of alleles each contributing a small amount can persist.[94]
A meta-analysis found that oxidative DNA damage was significantly increased in schizophrenia.[95]
About 0.3% to 0.7% of people are diagnosed with schizophrenia during their lifetime.[18] In 2017, there were an estimated 1.1 million new cases and in 2022 a total of 24 million cases globally.[2][19] Males are more often affected and on average have an earlier onset than females.[2] The causes of schizophrenia may include genetic and environmental factors.[6] Genetic factors include a variety of common and rare genetic variants.[20] Possible environmental factors include being raised in a city, childhood adversity, cannabis use during adolescence, infections, the age of a person's mother or father, and poor nutrition during pregnancy.[6][21]
Never eat the Chipi Chongular
hillow knight
Schizophrenia is a mental disorder[16] characterized by reoccurring episodes of psychosis that are correlated with a general misperception of reality.[6] Other common signs include hallucinations (typically hearing voices), delusions (i.e., paranoia), disorganized thinking,[9] social withdrawal, and flat affect.[6] Symptoms develop gradually and typically begin during young adulthood and are never resolved.[3][9] There is no objective diagnostic test; diagnosis is based on observed behavior, a psychiatric history that includes the person's reported experiences, and reports of others familiar with the person.[9] For a diagnosis of schizophrenia, the described symptoms need to have been present for at least six months (according to the DSM-5) or one month (according to the ICD-11).[9][17]
Angular circles
hollow knoght
hallow knaght
bogos binted
painfully slow but in an artistic way :)
hollow knight is cool
your honor, did I ask
hellow kneght
Portugese
blue
amber
1:42:45
NOW PLAYING
The Top 50 HARDEST Extreme Demons in Geometry Dash.
fnm04
49K views 2 days ago
New
1:42:45
NOW PLAYING
The Top 50 HARDEST Extreme Demons in Geometry Dash.
fnm04
49K views 2 days ago
New
The Towerverse by lord16
Salad
salad
chartreuse
green
australien
Location in Dirtmouth
Location in Dirtmouth
Gallery
Flail attack
Flail attack
Nail Slam attack
Nail Slam attack
Shadow Slam attack
Shadow Slam attack
Bretta's basement with Zote's statue
Bretta's basement with Zote's statue
Zote's statue turned gold
Zote's statue turned gold
Arena in Bretta's dream
Arena in Bretta's dream
Arena in Godhome
Arena in Godhome
Grey Prince Zote Radiant (Hitless) Hollow Knight
Grey Prince Zote Radiant (Hitless) Hollow Knight
Achievements
Achievement Dark Romance {S} Dark Romance
Defeat Grey Prince Zote.
10G
balls
anyway
white
Signs and symptoms
My Eyes at the Moment of the Apparitions by German artist August Natterer, who had schizophrenia
Schizophrenia is a mental disorder characterized by significant alterations in perception, thoughts, mood and behavior.[33] Symptoms are described in terms of positive, negative and cognitive symptoms.[3][34] The positive symptoms of schizophrenia are the same for any psychosis and are sometimes referred to as psychotic symptoms. These may be present in any of the different psychoses and are often transient, making early diagnosis of schizophrenia problematic. Psychosis noted for the first time in a person who is later diagnosed with schizophrenia is referred to as a first-episode psychosis (FEP).[35][36]
Positive symptoms
Positive symptoms are those symptoms that are not normally experienced, but are present in people during a psychotic episode in schizophrenia. They include delusions, hallucinations, and disorganized thoughts and speech, typically regarded as manifestations of psychosis.[35] Hallucinations occur at some point in the lifetimes of 80% of those with schizophrenia[37] and most commonly involve the sense of hearing (most often hearing voices), but can sometimes involve any of the other senses of taste, sight, smell and touch.[38] The frequency of hallucinations involving multiple senses is double the rate of those involving only one sense.[37] They are also typically related to the content of the delusional theme.[39] Delusions are bizarre or persecutory in nature. Distortions of self-experience such as feeling that others can hear one's thoughts or that thoughts are being inserted into one's mind, sometimes termed passivity phenomena, are also common.[40] Thought disorders can include thought blocking and disorganized speech.[3] Positive symptoms generally respond well to medication[6] and become reduced over the course of the illness, perhaps linked to the age-related decline in dopamine activity.[9]
no?
bet
I heard if you say your favorite youtubers name 3 times, you get pinned. caseoh caseoh caseoh
Real
I liked my own comment
no balls?
Bro thinks he's
Bro is not
black
The Towerverse by lord17