Transamination Reaction

This video explains the basics of transamination reactions. Special emphasis is given on aspartate transaminase (AST) and alanine transaminase (ALT).
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[@Fresharies]

I was going through so many videos and I was so confused until yours. Thank you!

[@DrMungli]

You are most welcome. I'm glad you have found my videos and found them most useful. You can consider SUBSCRIBING to this channel for regular updates. Please SHARE with your friends and classmates..

[@SN-mg9du]

I was lucky to watch this🥺🥺 Thank you sir 1000 times

[@VijayaMarakala]

Your students must be lucky. Respect

[@DrMungli]

+Vijay Marakala : Thank you Dr Vijay

[@akhilaneeshh]

😎

[@urbanproductions5584]

@@akhilaneeshh hi sir

[@qyyang1001]

The sudden appearance of red tie lolll Thank you so much! very helpful!

[@DrMungli]

Lol!! I too find it funny when I watched it again after getting your comment!! I guess the reason for this is I might have made a vide soon I have arrived to my office in the morning before my lecture. Before I complete the video some student might have visited my office and then went to lecture (wearing tie!!) and came back from lecture and completed the video with the red tie ON!! good observation though.. it means you have watched entire length of this video.. I'm glad if this video has helped you to understand transamination reactions.

[@draqibali2594]

Thanku sir

[@indiramalipeddi7048]

@@DrMungli ⁰

[@indiramalipeddi7048]

@@DrMungli ⁰⁰

[@rxl483]

This clears up that gap of information I had when learning this. Sincerest thank you from a P1 student . :D

[@DrMungli]

You are most welcome. I'm glad that this video has cleared some of your confusions about this topic. Best wishes.

[@rxl483]

at what point does this contribute to the Krebs cycle, and also are there any videos of yours on Beta oxidation of fatty acids ?
Thank you so much .

[@DrMungli]

I think I have more than 4 videos on beta oxidation. Just type beta oxidation and Dr Mungli in the search box and you will get them all.

[@anjilak6521]

sir i actually watched 4 videos of transamination before this but didnt got the concept
u made it clear within a single mechanism , second made it crystal clear *:))
thank u so much

[@yamilethvargasestrada5976]

Amazing explanation!!! Thank you so much.

[@mbbsscholar9297]

What a fantastic video it is.

[@mbbsscholar9297]

Hello

[@safeenagul2768]

Thanks sir is topic na. Mara 2 days waste kaya bt jasa hi aap ka vedo dakha bilkul easy ban gaya.... Thank you sir once again

[@adelerekayodejoshua]

God bless you sir, have been on these thing for months but I get it better now!

[@sherbangash6523]

Keep up the good work. Cheers from across the Atlantic.

[@rohanshetty4349]

Sir in Satyanarayana, along with Lysine and Threonine Proline and Hydroxyproline is also mentioned as the amino acids which cannot undergo Transamination. Please help sir having tests!😅😅

[@DrMungli]

Yes Rohan, there are four amino acids which do not undergo transamination. I forgot to mention proline and hydroxyproline. Thank you for this.

[@rohanshetty4349]

Dr.Mungli my pleasure sir!!☺

[@medicinediscussinggroup2272]

Dr.Mungli But sir in Lippincott lysine&Threonine given only.

[@urbanproductions5584]

@@rohanshetty4349 good observation broda

[@dr.kumaresanvadivel5146]

You are great doc!...we found a hard time in biochemistry but I was now lucky😊😊

[@DrMungli]

I'm glad that you have found my videos useful. make sure to SUBSCRIBE to the channel and click the bell icon to get regular updates.

[@hemanth.t8515]

Thank you sir." Eat sleep do biochemistry". It motivates me alot sir.

[@DrMungli]

You are welcome.

[@urbanproductions5584]

Brock Lesnar fan daaa

[@Sourya-]

Beautiful !! Beautiful !! Beautiful !!!
Awesome. Great for having such a great educator.....

[@akshayjouhary3897]

Sir,You explain very easy way , good concept sir ❤thank you

[@aqibsyed8198]

Sir apke videos bahut hi umda aur lajawab hai.allah aap ko bahut nawazein.

[@DrMungli]

Thank you.

[@nyesigajonan168]

I like the way you explain.
Thanks.

[@ak.5816]

Thanks a lot sir .
Your video makes it crystal clear for me🙏

[@ritachiaha8187]

Thanks soooo much ♥️...much love from Nigeria

[@Trisyalv]

And now I am more clear, Thank you very much Dr Mungli

[@sumesarachirag6656]

Thank you so much sir best explanation of transamination

[@shorts-kz4ur]

Oh my god I just got so many knowledge, every concept of this topic oh thanks sir... Your words are so indian wala hoke very nice to hear ...

[@keywordmcat2256]

another great lecture, quite amazing how you relate biochemistry and physiology and explain so clearly

[@DrMungli]

Thank you.

[@kuberakuberappa2315]

Prakash nimanu nodi tumba kushi aythu . nanu kuberappa ( gescom ) from bhujanganagar.thank u

[@rezaniloy2333]

Thank you very much sir,it became total clear!!❤❤❤❤love from Bangladesh 🇧🇩🇧🇩🇧🇩🇧🇩

[@rayan01]

That was very very very very very very helpful tkanks

[@subhamsahu9788]

thank you sir this video helped me lot to rectify my doubt on this topic .

[@DrMungli]

You are most welcome. I'm glad this video helped you. Kindly check out my playlist see if you find other videos useful as well.

[@akashrajr8602]

Very much thank sir . I was preparing for my exam this is a basic concept for amino acid metabolism .now iam clear with this topic sir

[@rajeswarannavinrajesh5754]

thank you very much sir , I was really confused on this particular topic. I'm now clear with it...

[@DrMungli]

You are most welcome. I'm glad this video has made this concept clear to you.

[@wallsandre7370]

Outstanding lecture that can be understood by any student,thank you sir for your concern for every medical student.....

[@harshali_kris]

Along with lysine and threonine, books say proline is an exception too. Is it true sir?

[@azhersyed8871]

Dr.Mungli
Thank you for the great and made easy clips on several important topics in biochemistry. It is very easy to understand your teaching. That said, could you also do a topic on Linkage Equilibrium and dysequilibrium ? a short clip would be very helpful. Would be great to listen to you
Thank you

[@DrMungli]

Thank you. I'm sorry to say that currently I teach biochemistry and its been many years since I taught genetics in class. May be in future I would consider it.

[@thejuniordoctor8225]

Respect and Adaabb From 🇵🇰🇵🇰❤❤🇮🇳🇮🇳

[@bushiii1365]

Thank you so much 😊😊😊😊😊😊😊😊😊😊😊😊😊😊

[@upscprep4560]

Excellent explanation

[@safiakara1868]

I found it very helpful.. Thanks

[@shahin2685]

Sir please give me answer....How is nitrogen removed from amino acids by transamination and Deamination?

[@shashwat5873]

Simply superb

[@debbieherbert1]

Am preparing for an exam and you have really helped me thanks so much sir

[@bilquisara8582]

Wow what a great explanation 👍👏👌 wah

[@oladunnioniti1548]

Well explained! Thank you sir

[@hassinayazid99]

may God bless you. thank you!

[@mehakkaushiksharma9775]

Easily understandable video. Thanks.

[@DrMungli]

You are most welcome.

[@shaliniannamalai4293]

Now i understood the concept sir thanq u so much sir 🙏🙏🙏

[@shavantagotra9091]

thank you ❤️❤️ sir ... for simlifying this ....

[@rameshjoshi8904]

Khoob khoob dhanyavaad

[@krienbergproductions8844]

Thank you ! you helped for the concept so much ~ ! amazing !

[@biswabhusanmahapatra6576]

Thank you sir... Great explanation 😊☺

[@DrMungli]

you are most welcome.

[@amitarani967]

Nicely explained sir

[@GEO-rm4wp]

You are a life saver
Thank u doc

[@DrMungli]

You are most welcome. I'm glad that these videos have been helpful to you.

[@tejas2707]

Thanks sir it's cleared all my doubts , please upload the video of deamination too

[@DrMungli]

You are most welcome. I will try to upload a video on deamination.

[@adityanarayandas9680]

thank you sir . cleared my concept!!❤ram ram.🙏

[@DrMungli]

You are most welcome.

[@fabiangriprosth9446]

And alfa-keto-glutmat gives one oxygen-atom to Aspartat aswell right? Thanks for a fantastic video

[@DrMungli]

You are most welcome

[@sri7352]

Sir in Satyanarayana biochemistry they gave that along with lysine,threonine proline and hydroxyproline also can’t undergo transamination sir

[@Science_Campus]

Despite the fact Proline is an amino acid, it doesn't have the amino group so how does it takes part in transamination reaction? Proline is an imino acid

[@smrutimorajkar7218]

Thank you sir, it was helpful

[@anisouddane3938]

Excellent explanation doc thank you

[@DrMungli]

You are most welcome.

[@huh757]

You saved me, thanx alottttttttttt ♥️♥️

[@DrMungli]

You are most welcome

[@snehamariappan8957]

Thnx a lot sir...kindly upload more videos sir

[@muhammadhuzaifa8649]

Thank you for such a wonderful lecture. Easy to understand

[@DrMungli]

You are most welcome.

[@HONEST3382]

You are amazing doctor , thank you

[@DrMungli]

You are most welcome.

[@atem2302]

yes I agree brilliant thank you.

[@stephanomleka402]

Yes I understand

[@abdiwalisheekh1335]

Thank you dr mungli

[@DrMungli]

You are welcome.

[@akshayjouhary3897]

Good job sir❤

[@stephanomleka402]

Thanks Dr I understand

[@kalyanpatil9264]

Is alanine always should bind to alpha ketoglutarate only to give pyruvte or it can also bind to glutamate?

[@DrMungli]

Alpha ketoglutarate is the acceptor of NH3 group during transamination

[@shrutishukla722]

Extremely good sir but please reduce the frequency of advertisement in between the lecture

[@DrMungli]

Thank you for the feedback. It is taken care now.

[@fakharmalik1410]

excellent sir

[@zakirzak1494]

In liver failure transaminases are high does that mean then more pyruvate or glutamate is produced or the reverse ? Thank you

[@apurbasarker7570]

Thank you, sir

[@Sadiqshaik-il6yk]

Thank you so much sir🙏

[@shradhashrivastava322]

very nice explanation

[@DrMungli]

Thank you. Best wishes.

[@spmishra9692]

thanks sir your video is very helpful

[@DrMungli]

You are most welcome. I'm glad these videos have been helpful to you. Make sure to SUBSCRIBE for more such videos and also please SHARE with your friends.

[@madhumitapradhan2289]

🙏🙏🙏. Excellent sir

[@vinodaneraye2579]

No one sir 👍🙏🙏👍🙏👍🙏🙏👍🙏👍🙏🙏👍🙏👍🙏🙏👍

[@nurindarwisyah7012]

THANK YOU SO SO MUCH FOR THIS VIDEO

[@tamimadnan7048]

love from Bangladesh sir ❤

[@gennexcombatir8126]

Thank you

[@varunchandran8005]

Super...
Osm...
Lecture sir....thank u

[@hintofjay]

thanks 😊

[@Ethiomedico]

Thank you Dr. Great love and respect for you.

[@ipigansilonaipigansi5037]

Thank you so much, its been really helpful.

[@aouraalmalkey6477]

thank u sir u helped me a lot

[@DrMungli]

You are most welcome. I'm glad my videos helped you.

[@thavaguru5053]

awesome sir

[@doni_sinha]

thanks a lot for such a nice explanation 😍

[@lonehumi8350]

Really helpful....tysm sir

[@DrMungli]

You are most welcome

[@mohibkhanafridi9922]

Nice lecture

[@theadrinka86]

I’m confused because my book says that threonine and SERINE are not transaminated, serine not lysine

[@DrMungli]

That is what I said in the video "except LYSINE and THREONINE" all other amino acids can undergo transamination reaction.

[@theadrinka86]

thank you Dr. Mungli, actually my book was wrong and you’re right, I looked it up on internet and they mentioned lysine as well. Thank you for replying

[@DrMungli]

You are most welcome. I'm glad now you know the correct information.

[@dr.michelbrosseaud.c.658]

would you need magnesium to stabilize the phosphate moiety

[@DrMungli]

I too think it is magnesium that does the job but at this time I'm not sure. Let me refer some reference books in biochemistry and get back to you.

[@0507MAZ]

This video really helps!! Thank you so much!!

[@DrMungli]

You are most welcome.

[@RohanSingh-my2ix]

if we label alpha ketonic oxygen of alpha keto glutarate, then where will we find that labelled oxygen at the end of forward reaction?

[@DrMungli]

Glutamate

[@RohanSingh-my2ix]

Dr.Mungli Can u explain how? Amino group of aspartate goes to @ketoglutarate and it becomes glutamate. So ketone group of @ketoglutarate must go to aspartate and become oxaloacetate. But u r saying dat if we label dat ketonic oxygen it will go to glutamate (not oxaloacetate). How?

[@sanakainat4963]

Thank you for the video. Some books mention about the recipient ketoacid which gain NH3 (ammonia) from amino acid could be any among 3 ketoacids ( ketoglutartate, oxaloacetate or pyruvate) which are catalyzed by Enzyme Group transaminases. ALT and AST amino transferases are specific for reaction b/w alanine and ketoglutarate and aspartate and ketoglutarate. pls clear this confusion.
Thankyou

[@DrMungli]

Hello Sana, please note that transamination reaction is reversible, in all transamination reactions one thing is common that is alpha-keto glutamate and glutamate, that means if you take alanine transaminase reaction, alanine (NH3) is transferred to alpha-keto glutamate that is when alpha-keto glutamate us converted to glutamate, when this happens alanine I turn is converted to its correspond keto-acid which is pyruvate. In other way round if glutamate (NH3) undergoes transamination reaction then it transfers it’s NH3 group to pyruvate (keto-acid) so pyruvate is converted to alanine, meanwhile glutamate is converted to alpha-ketoglutarate. So this can be applied to rest 16 amino acids except lysine, threonine, and proline

[@ridhazainab3225]

Respected Sir
In this transamination recation..is pyridoxal phosphate converted to pryidoxamine phosphate

[@medicinediscussinggroup2272]

Thank u so much sir.Great video@Medicine_discussing_group

[@DrMungli]

You are most welcome.

[@balbirsingh7653]

thank you very much sir .....
I am very clear with transamination now.....
sir, is there any video on deamination of amino acids by you

[@DrMungli]

You are most welcome. You can type search terms oxidative deamination and Dr Mungli you will get it. However, Im giving the link below but see if RUclips sends it to spam, check your spam report.

[@DrMungli]

ruclips.net/video/cMlGWcjwWik/видео.html

[@balbirsingh7653]

Dr.Mungli thank you very much sir

[@DrMungli]

You are most welcome.

[@AMRUTHARGOPAL]

Thank you sir😊

[@DrMungli]

You are most welcome

[@glavinmenezes2427]

Thank u sir

[@drbrijeshtiwari4858]

hi sir gud mng if yu make video systmetic chepter vise in order its good to study from begning to end acording to harper biochem book because video in random

[@DrMungli]

Good idea but you know how much time it takes for me to make each video. I will try to add more videos and make a playlist as per the chapters.

[@Vee_Luxe_Lips]

Thanks so much

[@DrMungli]

You're welcome!