Primary Syphilis - Agent, Pathogenesis, Clinical Features, Diagnosis, Treatment
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- Опубликовано: 21 дек 2023
- Hi. With this video, we will discuss Primary Syphilis and be better prepared for treating our patients. This video is directed towards dermatologists and is not at all advisory for non-medical personnel.
Introduction - 02:24
History - 05:16
Epidemiology - 06:36
Agent: Sub-species - 07:41
Agent: Treponema pallidum pallidum - 09:44
Structure - 11:41
Movements of Treponema - 13:27
Culture - 15:07
Structure of Chlamydia - 21:20
Immunology - 17:28
Pathology - 23:05
Clinical Features: Transmission - 25:12
Clinical Features: Incubation Period - 27:24
Clinical Features: Chancre - 29:06
Clinical Features: Chancre Variants - 33:12
Clinical Features: Complications - 35:20
HIV Co-infection - 36:01
Diagnosis - 38:20
Diagnosis: Dark Field Microscopy - 39:42
Diagnosis: Direct Fluorescent AB - TP - 41:12
Diagnosis: Biopsy - 42:17
Diagnosis: Electron Microscopy - 45:09
Diagnosis: PCR - 45:42
Diagnosis: Treponemal Test - 46:45
Diagnosis: Non-Treponemal Test - 50:12
Treatment: CDC - 52:44
Treatment: Penicillin - 56:18
Treatment: Penicillin Allergy - 59:56
Treatment: Penicillin De-sensitization - 01:01:46
Treatment: NACO / Syndromic Management - 01:04:07
Follow-Up - 01:04:55
Jarisch - Herxheimer Reaction - 01:06:09
Pregnancy - 01:11:20
Partner Management - 01:11:43
Further Reading - 01:14:15
End - 01:15:00
Good articles on Primary Syphilis:
1. Chapter 36 - Infectious Syphilis. In: Sexually Transmitted Infections, 2ed. Pg-429, Gupta S, Kumar B. ISBN: 978-81-312-2809-8
2. CDC URL: www.cdc.gov/std/treatment-gui...
3. NACO URL: naco.gov.in/sites/default/fil...
4. Dallé J, Ramos MC, Jimenez MF, Escobar FG, Antonello VS. Oral Desensitization to Penicillin for the Treatment of Pregnant Women with Syphilis: A Successful Program. Rev Bras Ginecol Obstet. 2018 Jan;40(1):43-46. doi: 10.1055/s-0037-1606274. Epub 2017 Aug 31. PMID: 28859210; PMCID: PMC10416178.
5. Taxy JB, Cibull T. Syphilis: A Contemporary Clinicopathologic Assessment. Am J Surg Pathol. 2020 Sep;44(9):1274-1281. doi: 10.1097/PAS.0000000000001523. PMID: 32568824.
6. Green EA, Fogarty K, Ishmael FT. Penicillin Allergy: Mechanisms, Diagnosis, and Management. Prim Care. 2023 Jun;50(2):221-235. doi: 10.1016/j.pop.2022.11.002. Epub 2023 Feb 26. PMID: 37105603. 
Развлечения
Sir aap bestest teacher ho in field of dermatology
Thank you 😊😊
May God keep using DR OBALAR to heal more people just as he treat my.HSV 2 and my husband HPV with herbs medicine, great work DR OBALAR on RUclips. Give him a try ❤
Awesomeness loaded sir wished there were two lectures per week sir aap best teacher ho ❤❤
Thanks a ton 😊😊
May God keep using DR OBALAR to heal more people just as he treat my.HSV 2 and my husband HPV with herbs medicine, great work DR OBALAR on RUclips. Give him a try ❤
Most awaited video in the STD series.
Thank you Sir!! 🙏
So nice of you 😊 keep watching. We will study syphilis together in detail. 😊😊
🙏🏻🙏🏻
May God keep using DR OBALAR to heal more people just as he treat my.HSV 2 and my husband HPV with herbs medicine, great work DR OBALAR on RUclips. Give him a try ❤
Mashallah very nice lecture you have covered everything plz if possible next lecture on tb
Thank you for your kind words 😊 We will finish with some venereology topics for 2-3 weeks, then we will shift back to dermatology. Thank you for the suggestion. I will definitely make one on cutaneous TB. 😀
you r great Allah salamat raka
May God keep using DR OBALAR to heal more people just as he treat my.HSV 2 and my husband HPV with herbs medicine, great work DR OBALAR on RUclips. Give him a try ❤
Very nicely explained Sir, i grasped all the concepts effectively.. Will the video on detailed diagnosis of Syphilis be out soon ?
Hi, I am glad I was able to help. 😊 Yes, the video will be out in a few weeks. Till then, you may watch the video lectures on secondary and tertiary syphilis, and other videos on the channel.
Oh okay, Thanks Sir😊😊
May God keep using DR OBALAR to heal more people just as he treat my.HSV 2 and my husband HPV with herbs medicine, great work DR OBALAR on RUclips. Give him a try ❤
May God keep using DR OBALAR to heal more people just as he treat my.HSV 2 and my husband HPV with herbs medicine, great work DR OBALAR on RUclips. Give him a try ❤
Sir please make a separate vedios for various guidelines like CDC, WHO, NACO, INDIAN for treatment
That is a good suggestion. I have heard that naco may get updated. I will surely make videos on that too. 😊
Please make a video on leprosy 🙏
Hi, I have done a video on the immunology of leprosy. It is available on the channel. I have also discussed drugs and alternate therapies in leprosy. I will be making new videos on different topics on leprosy. Any topics you would like to suggest?
May God keep using DR OBALAR to heal more people just as he treat my.HSV 2 and my husband HPV with herbs medicine, great work DR OBALAR on RUclips. Give him a try ❤
Sir..please make some videos in inflammatory dermatosis …
Surely!! Any particular topics you have in mind?
May God keep using DR OBALAR to heal more people just as he treat my.HSV 2 and my husband HPV with herbs medicine, great work DR OBALAR on RUclips. Give him a try ❤
Eczema and Psoriasis@@sabhderma
Treating chancroid with azithro sir 1:04:48
Perfect 😃😃
May God keep using DR OBALAR to heal more people just as he treat my.HSV 2 and my husband HPV with herbs medicine, great work DR OBALAR on RUclips. Give him a try ❤
Sir how desensitization done in case of penicillin allergic pregnant female?
Hi, thank you for your doubt. You may refer to this article for the protocol.
Oral Desensitization to Penicillin for the
Treatment of Pregnant Women with Syphilis:
A Successful Program
Doi- doi.org/
10.1055/s-0037-1606274.
There are many other protocols too. Some use the oral method, some may use intravenous method; but I reckon the oral one is better. Let me know if you have any issues.
Do you have pdf/ slides/ notes of this Sir ??
Hi, not yet. I am trying to make them available. Would they be useful? 🤔
Could you please tell the reference of your lecture……sir;;🙏
Hi, the references are on the second last slide of the lecture, and the URLs are in the description. Individual references are on the slides showing the related data. 😊😊