Urea Cycle

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  • Опубликовано: 28 сен 2024
  • ​​SUPPORT/JOIN THE CHANNEL: / @dirtymedicine
    My goal is to reduce educational disparities by making education FREE.
    These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
    For educational purposes only; NOT medical or other advice.
    Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
    Opinions are entirely my own.

Комментарии • 164

  • @adaildsouza
    @adaildsouza Год назад +68

    “Orange Coloured Cats Always Ask For Awesome Umbrellas” could help you remember the whole urea cycle.

  • @noedelafuentejr.9283
    @noedelafuentejr.9283 2 года назад +54

    May be given to decrease ammonia levels:
    1. Lactulose - acidify GI tract and trap ammonium (NH4+) = excreted
    2. Rifaximin and Neomycin - decrease bacteria producing ammonia
    3. Benzoate, Phenylacetate and Phenylbutyrate - for ammonia to react with glutamine or glycine and be excreted in the urine
    Hey Dirty thanks for your work. Been here since your last name was USMLE. I didn't know you got married to Medicine. Congrats and all the best.

    • @Asma-eu2mj
      @Asma-eu2mj 3 месяца назад

      cab someone guide me about usmle

  • @alyssayoung.2494
    @alyssayoung.2494 3 года назад +5

    This channel is a true blessing!

  • @alaamhajna6492
    @alaamhajna6492 4 месяца назад +3

    “Oh crab , carless Anna activated fire alarm unnecessarily“

  • @jwinterspring
    @jwinterspring 2 года назад +6

    This is very helpful. We don't have CVS here so I just made CPS "could pee somewhere". Lol.

  • @akankshyasunani7106
    @akankshyasunani7106 4 года назад +11

    Very basic way of letting understand...."pranam sir....🙏🙏🙏"

  • @hebabazina7265
    @hebabazina7265 2 года назад +13

    Love this channel and the little ways of remembering small details!!! Thanks a lot!

  • @sonya1500
    @sonya1500 3 года назад +91

    Dirty medicine, JJ medicine and AK lectures are the holy trinity of youtube education

    • @DirtyMedicine
      @DirtyMedicine  3 года назад +32

      Thanks. Now if only I had a better voice...

    • @sonya1500
      @sonya1500 3 года назад +20

      @@DirtyMedicine u have the voice of god

    • @Sammy.a1287
      @Sammy.a1287 3 года назад +12

      @@DirtyMedicine You have an amazing voice

    • @Sammy.a1287
      @Sammy.a1287 3 года назад +12

      @@DirtyMedicine In fact, I love you

    • @chisomchimezie
      @chisomchimezie 3 года назад +2

      @@DirtyMedicine 😹😹😹

  • @G4K
    @G4K Месяц назад +1

    Great Video Bro 💯 😂 Love From India 🇮🇳 🎉

  • @hrnbrain
    @hrnbrain 4 месяца назад

    Truly amazing.Very easy to understand and memorize. Thanks.

  • @favourachimba535
    @favourachimba535 3 года назад +2

    Great summary! I played it at 1.25x speed.

  • @cardiyansane1414
    @cardiyansane1414 2 года назад +2

    11:23 Or....you get a serum ammonia level and call it a day

  • @emmanuellaomenaya
    @emmanuellaomenaya 2 месяца назад

    You broke this topic downnnn ❤ thank youuu so much

  • @clarasafalanga8140
    @clarasafalanga8140 7 месяцев назад

    I have really enjoyed yr lecture continue with the same spirit

  • @yvonnemoreno8805
    @yvonnemoreno8805 3 года назад +2

    Whoa whoa whoa. This is an amazing explanation!

  • @mtvarisabolkvadze2752
    @mtvarisabolkvadze2752 3 года назад +5

    Only one enzyme is missing, which is arginase to convert arginine into urea and ornithine.

  • @chandooryamary1034
    @chandooryamary1034 4 года назад +1

    You made it very simple. ..... thnq Sir

  • @AhmadMarwanMustafaAlkhatib
    @AhmadMarwanMustafaAlkhatib Год назад +1

    يسعد دينككككك THANKS SOOOO MUCHHHHHHHHH

  • @kongmode
    @kongmode 2 года назад +1

    Man this is great video, thanks for your help man greatly appreciate 🙏 God bless you 🙌

  • @zeenatkhan7327
    @zeenatkhan7327 4 года назад

    Thanku uh made it very simple...it was tough to understand directly from book.. Thnks

  • @medjournals5235
    @medjournals5235 2 года назад +1

    Hi
    your video is great but you made a little mistake at 8.47 where you said that OTC is X-lined Recessive Disease when it's a X-linked Dominant Disease.

  • @mj-je7el
    @mj-je7el 4 года назад +2

    Im living that nightmare now ☠☠💔💔😥😥 could the medicin by one cure, get rid of it, so I can have a normal life and eat normal again????🙏🙏🙏

  • @thirstycrow10
    @thirstycrow10 2 года назад +1

    Great video!!! Excelente teachibg way 👏🏼👏🏼

  • @alazarmelash5482
    @alazarmelash5482 4 года назад +4

    Ammonia react with carbon dioxide how.......instead ammonia react with bicarbonate ion ???????

    • @kristihoxha25
      @kristihoxha25 4 года назад

      And ammonia formula,it is written as nh4+ on my book

  • @tafara-v5g
    @tafara-v5g 2 месяца назад

    thank you

  • @reuvenmeirherrera9580
    @reuvenmeirherrera9580 Год назад +1

    is there a purine and prymadine pathway videos? ty

  • @AnamWaseem-k7q
    @AnamWaseem-k7q Месяц назад

    Thank you loved it❤

  • @zainabjihan3973
    @zainabjihan3973 9 месяцев назад

    you are such a huge help, thank uuu 💗

  • @rtyt6411
    @rtyt6411 5 лет назад +1

    Excellent video....
    It's helps alot

  • @ajabisong
    @ajabisong 6 месяцев назад

    Beautiful video!

  • @sofimarie4019
    @sofimarie4019 2 года назад +2

    I remember it Bc CPS stands for child protection services. If you won’t let children use the restroom - CPS needs to be called upon. Using the restroom is a basic human right. 😂

    • @Seteniater
      @Seteniater Год назад

      I THOUGHT OF CHILD PROTECTION SERVICES TOO 😂😂😂😂

  • @medicinspirations
    @medicinspirations 6 месяцев назад

    Fascinating

  • @1412Z
    @1412Z Год назад

    Thank you!

  • @pimousse3595
    @pimousse3595 4 года назад +4

    compared to this video my teacher's book seems to be written upside down, and originally i am french

    • @etwl
      @etwl 3 года назад

      and the textbook is in another language that I dont understand hahaa

  • @Lyerbait13
    @Lyerbait13 2 года назад

    what a fantastic video. Subbed!

  • @mohitdhal1863
    @mohitdhal1863 4 года назад

    Very nicely done ty very much

  • @josebento1772
    @josebento1772 2 года назад

    Thanks a lot!

  • @Mohamed.AbdelNasser.
    @Mohamed.AbdelNasser. 9 месяцев назад

    thank you.. !

  • @AukiGJapon
    @AukiGJapon 3 года назад

    where is used the molecule of water

  • @learnwithbushra
    @learnwithbushra 4 года назад

    excellent

  • @diwu4125
    @diwu4125 Год назад

    Great

  • @زينبفلاحمحمّدعلي
    @زينبفلاحمحمّدعلي 4 года назад

    Verrrry Thnxxx🙏🏻🙏🏻🙏🏻🙏🏻god bless u

  • @sallyhungwe220
    @sallyhungwe220 3 года назад

    Thank you so much ❤️❤️❤️

  • @liebedich2441
    @liebedich2441 5 лет назад +1

    Great thanks

  • @illyashassan855
    @illyashassan855 4 года назад

    Thank you 🙏🏽🙏🏽🙏🏽

  • @Xavi3rNaidoo
    @Xavi3rNaidoo 3 года назад +1

    I'm going to CVS now

  • @davidarmienta1069
    @davidarmienta1069 3 года назад

    Do you have an amino acid catabolism video?

  • @patriciacarter6806
    @patriciacarter6806 3 года назад

    What happens to the orotic acid I have whitish sediment in my wee everyday thank you

  • @zeeshanhaider9055
    @zeeshanhaider9055 Год назад

    Nyc

  • @Trickyblade750
    @Trickyblade750 Год назад

    Thank you bro saved my ass with this one

  • @hema11901
    @hema11901 4 года назад

    Nice

  • @sonianaeem203
    @sonianaeem203 4 года назад

    thankyou for this

  • @collinsodhiambo1105
    @collinsodhiambo1105 5 лет назад

    U appreciate you so much

  • @hisanathasnim7087
    @hisanathasnim7087 4 года назад

    Thank u❣️

  • @vix200
    @vix200 3 года назад

    OMG it's coooooollllllllllllllllllll😭😭😭😭😭😭😭😭thank u so much keep going 😭😭😭😭❤️❤️❤️❤️❤️❤️

  • @alanchapman6558
    @alanchapman6558 2 года назад

    What about treating , this is not worth my time. The pharmaceutical industry needs to maximize profits.

  • @mostaanroya
    @mostaanroya 2 года назад

    Omg the best the best ❤️❤️🙏🙏🙏🙏🙏🙏

  • @shizanaveed1499
    @shizanaveed1499 3 года назад

    Amzzzzzinggg mannn

  • @ПашаКухарук-к4н
    @ПашаКухарук-к4н 3 года назад

    Девушка из 152, Привет)

  • @jeffbatey1632
    @jeffbatey1632 Год назад

    I love u

  • @kristenmegida9549
    @kristenmegida9549 3 года назад +28

    Sir please make more Biochemistry videos pleaseeeeeeeeeeee I love your channel you have made my Biochemistry life more easyyy ... I love your mnemonics. Well I will be having a Biochemistry exam today. Let's see how it goes. Please make more videos.
    You can add physiology, Anatomy, histology, genetics videos too yunno🙃

  • @ahmedgohar783
    @ahmedgohar783 3 года назад

    Thank you

  • @elijah1110
    @elijah1110 4 года назад +54

    wow when you play it at 2x speed, it sounds like normal speed. or maybe im just on too much caffeine rn idk

    • @alexandervangraff8475
      @alexandervangraff8475 3 года назад +2

      You probably have ADHD lmao

    • @elijah1110
      @elijah1110 3 года назад +2

      @@alexandervangraff8475 i actually do lol. This was before i was diagnosed though

    • @alexandervangraff8475
      @alexandervangraff8475 3 года назад

      @@demetriusgrant1214 Shut up you idiot fucking scammer

    • @thathaw7769
      @thathaw7769 2 года назад

      Thats what happens to me when I have 2 espresso a day before the exam.

  • @saurabhbawawohnhaftinnerem4429
    @saurabhbawawohnhaftinnerem4429 5 лет назад +35

    Once I clear the exam ..I m gona send u 500 usd

    • @DirtyMedicine
      @DirtyMedicine  5 лет назад +15

      Whatever you say :) Please use my Patreon if you want to support my channel: www.patreon.com/DirtyUSMLE

    • @Ogaramun
      @Ogaramun 4 года назад +4

      LOOLL MOOOOOODDDDD. BEAUTIFUL VIDEO. tHANKS

    • @ObscuraNocte
      @ObscuraNocte 4 года назад +1

      hey hope you got a pass :)

    • @saurabhbawawohnhaftinnerem4429
      @saurabhbawawohnhaftinnerem4429 4 года назад

      @@ObscuraNocte one month away from exam..and Indian govt is sending me to fight chineese

    • @ObscuraNocte
      @ObscuraNocte 4 года назад

      @@saurabhbawawohnhaftinnerem4429 holy shoot! sorry to hear that, wish you the best

  • @quackidasial
    @quackidasial 5 лет назад +43

    These are just in time for my usmle exam in a few weeks! Thank you!!

    • @oreoskitty001
      @oreoskitty001 4 года назад +1

      usmle? means you completed mbbs, heck, my teacher is making me do this for NEET🙄😶😑

    • @kingbuka9282
      @kingbuka9282 3 года назад +1

      hey hey, hope your exam went well :D

    • @emilyi771
      @emilyi771 2 года назад +2

      is this high yield for USMLE then? Thanks! About to take my USMLE exams

    • @jsann33
      @jsann33 2 года назад +1

      @@emilyi771 All the best emily !!

    • @Tabarekoday
      @Tabarekoday Год назад +1

      @@emilyi771 what are the results ؟

  • @oreskoul
    @oreskoul 3 года назад +11

    great lecture . Simply explained . Thank you !

  • @codyrussell5885
    @codyrussell5885 4 года назад +21

    Please consider including N-acetlyglutamate (NAC) as obligate activator for CPS1

    • @melongrey
      @melongrey Год назад

      Is it NAC or NAG?

    • @marky5493
      @marky5493 Год назад +1

      @@melongrey NAC

    • @melongrey
      @melongrey Год назад

      @@marky5493 alright! 👍🏻

  • @leonekaphiri763
    @leonekaphiri763 4 года назад +8

    brilliantly made simple..thank you i like it

  • @simoreta
    @simoreta 3 года назад

    Thank you

  • @pcms
    @pcms 4 года назад +6

    Well Explained!!! Bravo!

  • @collinsodhiambo1105
    @collinsodhiambo1105 5 лет назад +6

    Just about to sit my exams

  • @DivyankAgrawal_
    @DivyankAgrawal_ 4 года назад

    Thank you

  • @khawlahebboul5405
    @khawlahebboul5405 Год назад +1

    iam form algeria we stady in franch language but iam inderstanding better than my language stady thats mean you're explaning in level how anyone can enderstand thank you for this simple explanation

  • @sofnak
    @sofnak 4 года назад +4

    how come NH3 in the body which is reacting with CO2

    • @masacatior
      @masacatior 4 года назад

      Isn't the carbomoyl formed when glutamate combines with one phosphate of ATP? Glutamate is the main intermediate in amino transfer intracellularly.

    • @ronaldgaskin2511
      @ronaldgaskin2511 4 года назад

      Hi can anyone tell me what does 14.2 urea mean my brother tryed to commit suicide if I didn't find him in time the doctor said please can u tell me plz

  • @paulaoriana6740
    @paulaoriana6740 Год назад +4

    Great video!! Thank u dirty, 4 years later you are helping this med student :)

    • @noorel3bd04
      @noorel3bd04 6 месяцев назад

      Do you know anyone for histology and embryology

  • @il3mendo
    @il3mendo 26 дней назад

    I have Arg/cys dysfunction, celiac disease, a possibile polycytemia vera.
    What then I should eat ? Ahahahah

  • @ObscuraNocte
    @ObscuraNocte 4 года назад +3

    great lecture thank you!

  • @rapperthv
    @rapperthv 4 месяца назад +1

    4:46 arginino sucks 😔

  • @wicterwterr4245
    @wicterwterr4245 3 года назад +23

    Carbamoyl Phosphate Synthetase 1 requires N-Acetylglutamate as an activator.
    Great video! Thank you so much

  • @sadiakanwal1064
    @sadiakanwal1064 Год назад +1

    Awesome sir,gud job,keep it up

  • @paristonhill532
    @paristonhill532 5 лет назад +7

    don't forget they can ask which amino acid is used to produce ammonia and it is glutamine

    • @SAAli-dx2km
      @SAAli-dx2km 4 года назад +1

      Pariston Hill basically ur trying to N2 donors which are both Glutamine and Aspartate

    • @alazarmelash5482
      @alazarmelash5482 4 года назад

      Alanine also transport ammonia from tissue

  • @hiiii4854
    @hiiii4854 15 часов назад

    ❤❤❤❤❤

  • @shizanaveed8216
    @shizanaveed8216 4 года назад +2

    Awesomely explained ❤️❤️❤️

  • @MsBaster12
    @MsBaster12 2 месяца назад

    THANK YOU!!!!!

  • @trinicity
    @trinicity Месяц назад

    Thank you

  • @ujjawalgupta1800
    @ujjawalgupta1800 2 года назад +1

    Thank you sir ❤️

  • @2c-maribiancanicole281
    @2c-maribiancanicole281 3 года назад

    What happens if there's a problem in Argininosuccinate?

  • @reinerwilhelms-tricarico344
    @reinerwilhelms-tricarico344 3 года назад

    How come that before I watched this video I felt the urge to take a leek :-) And then later at 4:45 he used the wording "argenino sucks" but I bet that wasn't what he meant.

  • @ronaldjosephfernandez3723
    @ronaldjosephfernandez3723 3 года назад

    My case study was otd leading to non hepatic encephalopathy ! Hahahah

  • @twistedoracle4555
    @twistedoracle4555 4 года назад +1

    Awesome explanation!

  • @charlesagwuegbo5529
    @charlesagwuegbo5529 4 года назад

    I FUCKING LOVE YOU DUDE SLKSJSK

  • @anas-lq4uk
    @anas-lq4uk 4 года назад

    i fucking love you man you are so much help !

  • @audreyjoy7993
    @audreyjoy7993 3 года назад

    Having a CAT in a few... Thanks ☺️

  • @eeo.6175
    @eeo.6175 3 года назад

    It’s not available

  • @fayalhebs2478
    @fayalhebs2478 3 года назад

    You are the best !!!!

  • @afd5826
    @afd5826 2 года назад

    أشكركَ كثيراً ..

  • @akankshyasunani7106
    @akankshyasunani7106 4 года назад +7

    I am indian and belong to a middle class family....so although I secured good cgpa.....and I am hugely desperating to study abroad in USA.... but the money is big problem. And I can't choose study loan option in stake of my aim...so I am bound to study in India....clearing msc entrance....but thanks to this video....i can be able to study in America (abroad )from home....🙇🙆

    • @akarshkumar724
      @akarshkumar724 Год назад +2

      Don't feel defeated if you have money problems. Just focus on being the MASTER of what your job is. Obstacles & rejections will surely come, but view it as a part of the game; rather than some kind of injustice. & surely, you would reach someplace that is impossible for you to even imagine right now...
      I wish you all the best ❤

  • @ccedm4140
    @ccedm4140 4 года назад

    usuably. love your videos man

  • @alexmidani8380
    @alexmidani8380 Год назад

    great vid