Diffusing capacity of the respiratory membrane (DLco)
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- Опубликовано: 9 сен 2024
- What are the layers of the respiratory membrane? How much oxygen diffuses through the respiratory membrane per min? Why is carbon monoxide more suitable to measure the diffusing capacity of the respiratory membrane? Find out the answers in this video.
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Enjoyed learning the topic throughout!! Your way of teaching starting from basics and mentioning minute points is appreciable!! 👍👍
Thanks!
Sir your explanations are amazing sir....pls do continue such videos sirrr
Thank you
@@Johnwick0994 sure....thx
Brilliant explanation!
@@YS-qm2bf oh, thanks..!
I don't have words to thank to you sir!!!!
You are incredible😍🤩
Kindly upload more n more video for your students! Specially on gas exchange
Aesha Thakkar Sure. Thanks for the words of appreciation. Yes, more videos are coming up. First, i shall finish those topics which were already demanded.
Regards,
I don't have words to thank u.sir plz upload renal physiology
Ok. Point taken. More of renal physiology needs to be uploaded,
Regards,
Thank.you.so.much.for.your.informative.lecture.
Well explained sir 👍👍
Thankuu so much sir to discuss this topic...
Well explained!!!! 🤩🤩
thank you so much sir for all your physiology videos..!!
Most welcome !
Also, let me know any specific topic that requires a video, a detailed explanation.
Regards,
@@VivekSirsPhysiology sir regulation of respiration is a confusing topic sir .could you please make a video on it
@@govinds4388 Ok. Noted. Do you have the notes on this topic?
@@VivekSirsPhysiology I tried to read it from the text book sir.But I felt very difficult to clearly understand it
@@govinds4388 ok. Please send me your e-mail ID. I'll send you some reading material. The easy notes with diagrams. Till I make a video, these notes may be useful.
Diffusion limits equilibrium. Does it mean
1) diffusion properties of the gas
2) diffusion properties of respiratory membrane sir?
In the particular phrase 'diffusion limits equilibrium', it's talking about the diffusion property of the gas. However, the phrase itself is being used in the context of measurement of the diffusion capacity of the respiratory membrane.
Thanks for the query, though. I could be more specific while discussing the topic.
Regards,
@@VivekSirsPhysiology thank you sir!!
Sir can you tell in simple language why CO is called diffusion limited
I have watched the video but still bit confused sirr
Bcoz you said CO continues to diffuse then how come it is diffusion limited sir ??
Equilibrium NOT reached despite continued diffusion.
Just take this much part.
@@VivekSirsPhysiology Thank you sir
After perfusion oxygen and carbon dioxide reach equilibrium so that's the reason we are calling those gases perfusion limited gases sirr ??
@user-vl1kw6sj3f Yes. Right.
@@VivekSirsPhysiology Thank youu soo much sirr for replying
Dear sir,
How 11mmHg came as a pressure difference
It's the mean o2 pressure difference. If we apply the v/q concept we can understand why this happens
@@cmnaveenmusic sir plz give a proper calculation for it
Sir,why the limiting factor for diffusion of CO is diffusion? Does it have to do with lipid solubility of CO or any other factor?
Lipid solubility, and high affinity to combine with Hb, these two factors do not allow CO to reach equilibrium, and become the limiting factors.
@@VivekSirsPhysiology thankz ,sir.
Sir, in semulingam diffusing capacity of oxygen is 21ml/min/Hg
I'm a bit confused here, can you please help
Yes. That's right. 21-23 mL/min/mm Hg for oxygen. To understand these values, they should be read in the reverse fashion (from right to left). So, here it is - For every 1 mm Hg, in every 1 min, 21 mL of oxygen will diffuse through the respiratory membrane.
Further, what is this 1 mm Hg?
That's the PRESSURE GRADIENT across the respiratory membrane.
So, if the pressure difference from alveolus to blood is 1 mm Hg, then in 1 minute, 21 mL of oxygen will diffuse (through resp membrane, from alveolus to blood).
Pressure gradient is about 11 mm Hg. And hence (21 X 11 =) about 230 mL of oxygen diffuses every minute.
[Actually, it is 230-250 mL oxygen diffuses from alveolus to blood, and the same amount of oxygen is used by the body every minute.]