your enolate series is a life saver, u arranged it according to topic and im just following along with you, finding each one of them easy thanks to ur tricks and well explained mechanisms. thank you so much!!!!
Leah you are doing god’s work!! I was struggling with this mechanism and deciding which alpha Carbon to attack but your tricks are making it more easy to follow
I'm sorry, but this video doesn't cover the acid-catalyzed aldol reaction. Since I don't offer tutoring over social media, for help with questions like this and more, I recommend joining the organic chemistry study hall. Details: leah4sci.com/join or contact me through my website leah4sci.com/contact/
at 7:41 , why is this molecule symmetrical? If you count from left, the first ketone group you will meet is on carbon 3; whereas if you from right then the first ketone group you will meet is on carbon 4.
She means that the middle two carbons between the two carbonyl groups are the same. You can either use the hydrogens on carbon #2 or carbon #4 (the green alpha carbons, not the red ones). She’s not saying the entire molecule is symmetrical. She’s saying there is a symmetry between the two carbonyls from carbons 1, 2, 4, and 3.
Oh wow you're right 🤦, I meant to draw a different molecule so that it would be perfectly symmetrical. I hope the remainder of the problem still helped you with this topic
Would it be possible if you make more chemistry videos . I'm doing specialist in Biological chemistry at University of Toronto.Once again for saving my GPA.
I'd been stuck on how to do these reactions for DAYS after my prof had been droning on about it for HOURS and this video had me understanding it in the first THREE MINUTES. Im screaming thank you.
Hi Leah, I have a question: when bisecting the enone, how do you know where to place the second oxygen? On the top half or bottom half of the enone? Can you explain, and give some detail? Thank you so much! Please let me know. (I have an exam on Wednesday.) Best, Rina
For which specific example in this video are you asking this question? I think we should focus less on whether it's the 'top or bottom' half and more on placing the oxygen on the correct carbon of the compound.
@@Leah4sci Hey no problem; thanks for making such high quality videos! By the way, if you ever want me to a comment a pun on a specific topic, just let me know.
You explain so so so very well !! Your videos clear all my doubts like forever. Thank you so much Leah! Keep making more videos like this. I am struggling really hard with organic chemistry and your videos inspire me to learn it in a better way. Thank you
Yes. For help with topics like this and more, I recommend joining the organic chemistry study hall. Details: leah4sci.com/join or contact me through my website leah4sci.com/contact/
How would you know - when a base takes off a proton - if the electrons stay on the carbon OR if they make a double bond and kick up to the oxygen. Is there a trick for that?
If both can happen, and they are resonance forms of each other, what you actually get is an in-between hybrid. What you choose to SHOW in the mechanism depends on how you learned it, and which step you're on. I typically show resonance with the electrons 'parked' on oxgyen until carbon is ready to attack
I'm sorry, I don't have the time and staff to translate to other languages. :( But maybe turning on the closed caption and slowing down the video will help.
You get multiple mixed products. For the trick, assuming they can each be an 'A' or 'B' write out the following combos. A-A A-B B-B B-A Where the first attacks and the second gets attacked. If a ketone is reactive on BOTH ends you get even more options. For your sanity I hope you don't get that on your exam ;)
All of my videos can be found here: leah4sci.com/organic-chemistry-syllabus-companion-topics-list/ For even more help with each of these topics, I recommend joining the orgo study hall. Full details: leah4sci.com/join
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Exactly 5 years after uploading this video, you're still making a difference!
Happy it's helped you!
@@Leah4sci it's also help me today thanks alot
First video that got recommended to me when I searched Intramolecular Aldol and it was worth it, very clear explanation. Thanks dude
Glad the search brought you here and that you found it helpful!
This is the first time I've understood intramolecular aldol reactions thank you so much!
You're so welcome! Glad I could clear it up for you!
I have been SEARCHING for someone to be able to explain this easily and you SERVED! THANK YOU!
You're very welcome! I'm so glad you found the video helpful.
I can not explain How much Important You are to me.. I wish you were my Chemistry Teacher all the time 😢😢🤍🤍🤍🤍🤍🤍🤍🤍🤍🤍🤍🤍🤍🤍🤍🤍🤍🤍🤍🤍🤍🤍🤍
I am SO happy to be able to help you in your course!
your enolate series is a life saver, u arranged it according to topic and im just following along with you, finding each one of them easy thanks to ur tricks and well explained mechanisms. thank you so much!!!!
So happy that it matches perfectly. I Hope the tricks save you time and confusion on your exam
Thank god I managed to find someone who shows the mechanism properly! Much appreciated. Those animations are great BTW 👍
Glad I could help!
I totally agree! ^*
It was lovely to find something as didatic as that! Your explanation is so simple, yet so detailed.
Thank you so much!
Leah you are doing god’s work!! I was struggling with this mechanism and deciding which alpha Carbon to attack but your tricks are making it more easy to follow
Aww, thanks for your kind words! I'm so happy that I'm able to clear things up for you!
Thanks for making this reaction so easy....Ur teaching is fab!!!!....❤️❤️love from India🌸🌸
My pleasure 😊
You have no idea how helpful this video has been for me. I just can't thank you enough!
I'm so glad to hear that!
I have to say..you have been so helpful through the years❤ i am really grateful
Happy to help!
you are literally a lifesaver! ochem 2 exam tmw and i always get confused where to attach the molecules!
So glad I could help!
You've put in a way that's so easy to understand, thank you
You're very welcome, I'm happy to hear that this helped you understand!
When in intramolecular cyclization of aldol condensation is proceed with acid catalyzation then how can we know the initial reactant?
I'm sorry, but this video doesn't cover the acid-catalyzed aldol reaction. Since I don't offer tutoring over social media, for help with questions like this and more, I recommend joining the organic chemistry study hall. Details: leah4sci.com/join or contact me through my website leah4sci.com/contact/
Thank you very much, ma'am!
It really did help me to understand the mechanism clearly.
Have a good time. :)
You're so welcome!
I’m watching you from The Gambia 🇬🇲
You’re phenomenal
Aww, thanks so much!
@@Leah4sci you’re welcome
Which university are you lecturing?
I aced ochem 1 AND 2.. Thank you! 😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭
Wow, congratulations on crushing orgo!!!
Amazing explanation thank you so much
Glad it was helpful, and you're very welcome
at 7:41 , why is this molecule symmetrical? If you count from left, the first ketone group you will meet is on carbon 3; whereas if you from right then the first ketone group you will meet is on carbon 4.
She means that the middle two carbons between the two carbonyl groups are the same. You can either use the hydrogens on carbon #2 or carbon #4 (the green alpha carbons, not the red ones). She’s not saying the entire molecule is symmetrical. She’s saying there is a symmetry between the two carbonyls from carbons 1, 2, 4, and 3.
Oh wow you're right 🤦, I meant to draw a different molecule so that it would be perfectly symmetrical. I hope the remainder of the problem still helped you with this topic
u are absolutely
a blessing in my life .
Glad I could help :)
Would it be possible if you make more chemistry videos . I'm doing specialist in Biological chemistry at University of Toronto.Once again for saving my GPA.
Great teaching 😊
Thank you so much! :)
I'd been stuck on how to do these reactions for DAYS after my prof had been droning on about it for HOURS and this video had me understanding it in the first THREE MINUTES. Im screaming thank you.
Glad I could help!
THANK YOU SO MUCH😁🤗
You're very welcome!
You really are amazing. I was banging my head against the wall trying to figure out the right way to draw this quickly for the MCAT. Thank you 🙏
Glad I could help!
Very helpful. Thank you for sharing ur knowledge with us .
Love from India
My pleasure!
Tq so much mam its very useful to me nice explanation 👍
You're so welcome 😊
Hi Leah,
I have a question: when bisecting the enone, how do you know where to place the second oxygen? On the top half or bottom half of the enone? Can you explain, and give some detail? Thank you so much! Please let me know. (I have an exam on Wednesday.)
Best,
Rina
For which specific example in this video are you asking this question? I think we should focus less on whether it's the 'top or bottom' half and more on placing the oxygen on the correct carbon of the compound.
Thank you so much I am study with you . 🙏🏼🙏🏼👩🏻🎓from Iraq .
You're very welcome!
Intramolecular? More like "Interesting and spectacular!" Thank you so so much for making all of these videos.
You're welcome! Thanks for commenting!
@@Leah4sci Hey no problem; thanks for making such high quality videos! By the way, if you ever want me to a comment a pun on a specific topic, just let me know.
Thank you so much 😊
You're welcome 😊
You explain so so so very well !! Your videos clear all my doubts like forever. Thank you so much Leah! Keep making more videos like this. I am struggling really hard with organic chemistry and your videos inspire me to learn it in a better way. Thank you
Awww thanks for your kind words! I'm sorry you are struggling, but so happy to know my resources are helping you.
I really wanna thank you for these videos, you are my personal tutor now. I feel like I dont need my professor anymore.
happy to help!
Can we perform intra molecular aldol reaction in presence of H3O+
Yes. For help with topics like this and more, I recommend joining the organic chemistry study hall. Details: leah4sci.com/join or contact me through my website leah4sci.com/contact/
For sure this is so much helpful Leah
So happy to help!
Amazing!!! Thank you so much!! I was so confused and your teaching made it crystal clear 😊😊
You're very welcome! Glad I can help :)
You are an awesome tutor. Thank you.
You're so very welcome!
that was very helpful :) thanks!
Glad it was helpful!
How would you know - when a base takes off a proton - if the electrons stay on the carbon OR if they make a double bond and kick up to the oxygen. Is there a trick for that?
If both can happen, and they are resonance forms of each other, what you actually get is an in-between hybrid. What you choose to SHOW in the mechanism depends on how you learned it, and which step you're on. I typically show resonance with the electrons 'parked' on oxgyen until carbon is ready to attack
Mam i am not understanding your laungvese???
I'm sorry, I don't have the time and staff to translate to other languages. :( But maybe turning on the closed caption and slowing down the video will help.
Hey beautiful thanks for such great explanation
You are so welcome!
Very good
Thanks!
but what to do if the compound to be condensed using aldol condensation is not symmetric.
Use the same logic for evaluation as you would for a cross Aldol when evaluating which end of the molecule will attack vs get attacked
Amazing❤
Thanks 😄
It very helpful!!!
Glad you found it helpful :)
what happens when the molecule is not symmetrical , which alpha do you choose?
I'm sorry, but I don't offer tutoring through RUclips comments. For help with this, I recommend joining the orgo study hall: leah4sci.com/join
You are the best
Thank you
JUST Awesome!
Glad you like it!
Thank you so much for you help! Your videos are the best!!!
You are welcome! Glad you enjoy them :)
Wow Leah u are super super great! You saved me a sh$t load of time 🤓!
Glad to help!
This is a great help ever. Thank you so much!
You're so very welcome!
So what happens when you have an unsymmetrical keto aldehyde?
You get multiple mixed products. For the trick, assuming they can each be an 'A' or 'B' write out the following combos.
A-A
A-B
B-B
B-A
Where the first attacks and the second gets attacked. If a ketone is reactive on BOTH ends you get even more options. For your sanity I hope you don't get that on your exam ;)
thanks
you're welcome
Where is hyperconjugation , inductive effect and carbocation
All of my videos can be found here: leah4sci.com/organic-chemistry-syllabus-companion-topics-list/
For even more help with each of these topics, I recommend joining the orgo study hall. Full details: leah4sci.com/join
thanks so much i appreciate your help!~~
You are very welcome!
I HAVE A PROBELEM WITH A MICANISEME LEACH
For help with this and more, I recommend joining the organic chemistry study hall. Full details: leah4sci.com/join
Plz a video diazocupling reaction
In 2024
?
i found ur videos way too late xD
Better late than never?
THANK YOU SO MUCH😁🤗
You're welcome!