Thank you for condensing years of careful study on treatment of IBS/IBD into this great advise. Years ago I was able to overcome IBS with the 5:2 diet which increases butyrate producing bacteria by fasting much of 2 days of the week, and by adding inulin and healthy foods. The remission lasted for months while my diet worsened. This advice could have saved me years of trouble and hundreds of dollars worth of supplements that I didn't need.
There is some complication here not addressed in this video. Metformin works by aiding the gut biome and then the gut biome reduces blood sugar and leaky gut syndrome. Metformin has little direct effect. Metformin mostly works on the gut. However, like how fermented foods help the gut biome, if one has IBS or another issue, they need to start slow. Diving into the deep end causes problems. Taking Metformin isn't a great idea if you have obvious gut issues, but if you have mild gut issues, it may help get rid of your gut issues. Berberine too. Berberine works the same way, aiding the gut biome. (Also fermented foods shouldn't be eaten every day, as too much doesn't help anyone's gut biome. Every other day max, if not once every 3 to 5 days.)
I would argue that there are better safer ways to manage pre diabetes than resorting to medications that lower blood sugar. America has a major problem with diets. Roughly 50% people will develop disbetes by 2040. blood Diabetes hardly existed 50-60 years ago. Also, Metformin can also causing B12, 6 and other deficiencies. Any short term gains or positives of metformin can be better achieved with diet, not to mention that many natural herbs when compared to metformin effectiveness work just as well if not better(no side effects) compared to metformin.
ESTE VIDEO HA SIDO DE GRAN VALOR PARA MI PORQUE EN PRIMER LUGAR ME ACLARA EL PROBLEMA QUE PADESCO Y ME SUGIERE UN ORDEN PARA INCREMENTAR MI MICROBIOTA POSITIVA . APRECIO MUCHO TU AYUDA . MUCHAS GRACIAS POR COMPARTIR TUS CONOCIMIENTOS.
Great video. Really good information. I have three questions please. 1) You mentioned histamine intolerance due to poor gut health. Are you suggesting improving gut heath will help reduce histamine reactions? 2) Do you think repairing the gut by improving diversity could help people regain their ability to digest lactose? 3) Do you believe improving gut diversity could help with bacterial infections such as H.Pylori? Thanks
Your video hits so many key points i started a diet with out doing my Genova test first and further damaged my gut i desperately need help interpreting my test doc
I was diagnosed with IBS 3 years ago, I suspect I also have Leaky Gut. After initial diagnosis I went on the Low Fodmap diet which worked well. But I may have gone down with Covid & stress shortly afterwards... after which I became intolerant to gluten dairy and foods I had no previous problem with. I have tried various probiotics with no improvement. I tried a butyrate supplement ..but during the night I experienced bad nausea.. similar to what I experience with IBS. I wonder if I'll ever be normal again .. it impacts on every area of life.. my energy levels are poor. Here in the UK after doctors test you for gut disease coeliac etc etc if all is negative they tell you you have IBS and send you to a nutritionist who put you on Low Fodmap and you are left to get on with it.
Very good videó! thank u! We would like to listen more about the nowdays gut or diet research ! I just would like to complete this videó with hormon importance! Hormon direct digestion! And the imortance of stress avoiding or handling! Many people s stomach gate didnt close well and it cause many problem like glutén, or lack of enzymes! And if u follow the right diet and u want to speed up ur healing akupunkture is very effective!
Thanks a million for all your videos, they have come as a blessing to me right now with my diverticulitis flaring up. Can you please answer this question: I tried many times to take fish oils for the omega-3. Absolutely cannot digest it! Keeps coming up. I imagine I don't have the bile salts to break that down. I tried adding lemon juice to it but not much success. Thanks for your feedback.
Yes butyrate is great for gut but real question is why are bacteria not producing SCFA like butyrate. Butyrate is a temporary bandaid until you fix the real problem.
@@DrRichardHagmeyer Thank you for the reply. The link you provided takes me to your website. There is no info there for the functional stool test. I signed up and gave you my email. Hopefully you will send me more info on the stool test. I live in NYC. Thanks.
There are many reasons for a bad response to probiotics. In some cases it’s not really a bad response, it’s a change of the microbiome. S.boulardii is a good yeast that crowds out pathogenic yeast, it also raises SIgA and helps combat H.pylori.
No. Long term sustainable production of SCFA requires having a balanced micrbiome. SCFA are primarily produced by break down of starches. In order to do this, you need key commensal bacteria to do this. Watch the video first more details
No one ever talks about the many who have messed up immune systems where they actually have high levels of SCFA that are causing neurotoxicity. When they go on low carb low fiber diets, they get better due to the starving off of "good" bacteria that their immune system is unable to keep under control or is overreacting to and causing auto immunity.
Please share some studies on this topic. I’d like to see more and understand the mechanism. Which SCFA in particular and how high are we talking? What kind of autoimmune disease has been associated with this? SCFA impart a list of benefits so long I can’t take time to Write them all out.
Dr. Eduardo Beltran is helping people reverse autoimmune diseases with high dose Vit D. He has a documentary on RUclips called The LGS (leaky gut) Protocol. Worth taking a look at some of his videos and he just put out a book on Amazon too. Great doctor!
What are the symptoms of high SCFA? Probably obese yet low blood sugar people, because SCFA trigger GLP-1 which secretes insulin but are also SCFA are associated with high firmicutes (=obesity)
Hi Bee, As you know, Once a person has had a portion of their colon removed, it changes everything. My initial thoughts would be that they would have very limited benefits- the same with probiotics. I have not seen research that shows one way or another.
@@DrRichardHagmeyer thank you for the swift reply. I was hoping that a supplement would help with inflammation of the small intestines and also systemically... Can't seem to find anything that helps with that. 😔 But yeah, it's been really tough figuring out my health pre surgery and even moreso post colectomy. You're right about how having the colon removed changes everything and there's barely any research about it. Does your office have experience working with people with ileostomies (including the nuances it causes systemically)?
Bee my pleasure! Wish I had more info for you. It’s unchartered territory and becomes a lot of trial and error. I do have patients who have had surgery. I would focus on following an ant inflammatory diet as well as identifying nutritional deficiencies- this would be one of my major concerns if I was you.
There is lactic acid bacteria in small intestine and helps for small intestine problems search vsl 3 and other probiotics , some bacteria can be benefitfull for small intestine also , you still have stool exit so you still have bacteria there also you are fermenting food by digesting it so bacteria still important
I took a butyrate supplement in the evening and then I woke up in the middle of the night with my gut feeling like it was on fire. I felt like I had the worst fever I've ever had, but it was in my gut. I waited a week and took the butyrate supplement again and the same thing happened. Have you ever heard of this happening and what do you think may have caused this reaction? Thanks
Doesn't look like he answered. Shame. What else was in this supplement? It may not have been the butyrate, it may have been mixed with a concentrated spice like cayenne pepper or a fermented food.
Never heard of that- sorry for late reply. I use butyrate ALL the time with patients. Did you purchase your supplements off of Amazon or from your doctor? I don’t ever recommending buying supplements off of Amazon.
@@DrRichardHagmeyeri did get a butyric ácid, how i can take it ? In the bottle said it is dangerous it needs to be handle with special materials and a gas masck .
Anna Moros if your SCFA levels are low then you need to get your levels up. Short chain fatty acids are so important for gut health and overall metabolic health as well. They regulate many aspects of health.
PPA interacts with brain cells via G-protein-coupled SCFA receptors including GPR4129. Since PPA (3 carbons) is the most potent activator of GPR41, and due to the prevalence of Clostridia spp., Bacteriodetes, and Desulfovibrio spp. in ASD microbiome and its association with elevated PPA and gliosis30, we hypothesize that elevated PPA may tamper with neural cell plasticity and differentiation in vitro leading to gliosis, increased inflammatory profile, and disturbed neural connectivity, similar to ASD.
@@DrRichardHagmeyer I'm trying to help a child with ASD and came across PPA the other day and it seems to be very prevalent in people with ASD. Do you think a healthy ketogenic diet would reduce PPA or have you any suggestions on how to reduce it.
The concern I have on ketogenic diet would be the impact it would have on the microbiome. Lowering PPA might not be expected or hoped for result on keto. PPA is only one SCFA. This child needs testing before implementing such a restrictive diet. I would Also be concerned about prior nutrition and mineral status. Kids with Autism have many considerations. The study I referenced shows neuro glial inflammation with elevated PPA- but that does not mean this is what is happening with your client- Test! Test! Test! Without testing you are playing the what if game and only treating symptoms. You will want to focus on the dysfunctional physiology.
Thank you for condensing years of careful study on treatment of IBS/IBD into this great advise. Years ago I was able to overcome IBS with the 5:2 diet which increases butyrate producing bacteria by fasting much of 2 days of the week, and by adding inulin and healthy foods. The remission lasted for months while my diet worsened. This advice could have saved me years of trouble and hundreds of dollars worth of supplements that I didn't need.
soil based and or d- lactate producing probiotic bacteria can f you up
Just found your video today! Sure wish I had a medical person in my life like you!
So glad you liked the video! Lots of great videos for you here! Reach out if your interested in having a case review. www.DrHagmeyer.com
There is some complication here not addressed in this video. Metformin works by aiding the gut biome and then the gut biome reduces blood sugar and leaky gut syndrome. Metformin has little direct effect. Metformin mostly works on the gut. However, like how fermented foods help the gut biome, if one has IBS or another issue, they need to start slow. Diving into the deep end causes problems. Taking Metformin isn't a great idea if you have obvious gut issues, but if you have mild gut issues, it may help get rid of your gut issues. Berberine too. Berberine works the same way, aiding the gut biome.
(Also fermented foods shouldn't be eaten every day, as too much doesn't help anyone's gut biome. Every other day max, if not once every 3 to 5 days.)
I would argue that there are better safer ways to manage pre diabetes than resorting to medications that lower blood sugar. America has a major problem with diets. Roughly 50% people will develop disbetes by 2040. blood Diabetes hardly existed 50-60 years ago. Also, Metformin can also causing B12, 6 and other deficiencies. Any short term gains or positives of metformin can be better achieved with diet, not to mention that many natural herbs when compared to metformin effectiveness work just as well if not better(no side effects) compared to metformin.
ESTE VIDEO HA SIDO DE GRAN VALOR PARA MI PORQUE EN PRIMER LUGAR ME ACLARA EL PROBLEMA QUE PADESCO Y ME SUGIERE UN ORDEN PARA INCREMENTAR MI MICROBIOTA POSITIVA . APRECIO MUCHO TU AYUDA . MUCHAS GRACIAS POR COMPARTIR TUS CONOCIMIENTOS.
So glad it helped!
I started taking butyrate after reading its low in alcoholics
Immediately I had no cravings whatsoever for the after work wine
Fantastic!!!! And I beg your gut thanks you in more ways than one!
What a great video, clear and concise. Very informative.
wow, at last, someone who mentions histamines in fermented foods.
Great video. Really good information. I have three questions please.
1) You mentioned histamine intolerance due to poor gut health. Are you suggesting improving gut heath will help reduce histamine reactions?
2) Do you think repairing the gut by improving diversity could help people regain their ability to digest lactose?
3) Do you believe improving gut diversity could help with bacterial infections such as H.Pylori?
Thanks
1. Yes
2. Yes
3. Yes
Thank you for the info. Great video!
Good 👍 information on butyrates, thank you 🙏
Your video hits so many key points i started a diet with out doing my Genova test first and further damaged my gut i desperately need help interpreting my test doc
Glad you liked it!
What lab do you recommend? Thank you. How do we get in contact with you please
visit www.DrHagmeyer.com for information on testing.
I was diagnosed with IBS 3 years ago, I suspect I also have Leaky Gut. After initial diagnosis I went on the Low Fodmap diet which worked well. But I may have gone down with Covid & stress shortly afterwards... after which I became intolerant to gluten dairy and foods I had no previous problem with. I have tried various probiotics with no improvement. I tried a butyrate supplement ..but during the night I experienced bad nausea.. similar to what I experience with IBS. I wonder if I'll ever be normal again .. it impacts on every area of life.. my energy levels are poor. Here in the UK after doctors test you for gut disease coeliac etc etc if all is negative they tell you you have IBS and send you to a nutritionist who put you on Low Fodmap and you are left to get on with it.
Me too! From U.K. same experience
Good full of information.
2:41 Dr. Hagmeyer lists the probiotic strains helpful.
I think these strains can be dangerous especially in a compromised gut.
Which probiotic brand has these strain combination?
Very good videó! thank u! We would like to listen more about the nowdays gut or diet research ! I just would like to complete this videó with hormon importance! Hormon direct digestion! And the imortance of stress avoiding or handling! Many people s stomach gate didnt close well and it cause many problem like glutén, or lack of enzymes! And if u follow the right diet and u want to speed up ur healing akupunkture is very effective!
Thanks a million for all your videos, they have come as a blessing to me right now with my diverticulitis flaring up. Can you please answer this question: I tried many times to take fish oils for the omega-3. Absolutely cannot digest it! Keeps coming up. I imagine I don't have the bile salts to break that down. I tried adding lemon juice to it but not much success. Thanks for your feedback.
Excellent!
Can you do a video on supplements to support and help MCAS in the gut? Will butyrate help?
Yes butyrate is great for gut but real question is why are bacteria not producing SCFA like butyrate. Butyrate is a temporary bandaid until you fix the real problem.
So are you saying that Butyrate will not fix the gut taking long term ? Of course with good diet
Some say to avoid legumes and grains altogether
Fantastic!
And zeominerals are very helpfull too!
What are zero minerals?
Which brand is the best ????
Whichever one helps raise your levels on retesting. I have to be careful about recommending any Brands.
Has anyone tried to make SCFA as the main fuel source for mice to see what happens?
Where do you get a functional stool test?
www.drhagmeyer.com/comprehensive-gi-effects-functional-panel/
@@DrRichardHagmeyer Thank you for the reply. The link you provided takes me to your website. There is no info there for the functional stool test. I signed up and gave you my email. Hopefully you will send me more info on the stool test. I live in NYC. Thanks.
I'd like to know if this will help TMAU sufferers
It’s been helping with some type 2 tmau sufferers along with probiotic foods
What if i don’t react well to a boulardi i get very bad fog and head ache should i still consider taking soil based probiotic’s?
There are many reasons for a bad response to probiotics. In some cases it’s not really a bad response, it’s a change of the microbiome. S.boulardii is a good yeast that crowds out pathogenic yeast, it also raises SIgA and helps combat H.pylori.
WoULDn't a vinegar water drink immediately bring up scfa in stool?
No. Long term sustainable production of SCFA requires having a balanced micrbiome. SCFA are primarily produced by break down of starches. In order to do this, you need key commensal bacteria to do this. Watch the video first more details
Is it normal for butyrate supplement to cause diarrhea initially? Just 1 dose and my daughter had diarrhea
No one ever talks about the many who have messed up immune systems where they actually have high levels of SCFA that are causing neurotoxicity. When they go on low carb low fiber diets, they get better due to the starving off of "good" bacteria that their immune system is unable to keep under control or is overreacting to and causing auto immunity.
Please share some studies on this topic. I’d like to see more and understand the mechanism. Which SCFA in particular and how high are we talking? What kind of autoimmune disease has been associated with this? SCFA impart a list of benefits so long I can’t take time to
Write them all out.
Dr. Eduardo Beltran is helping people reverse autoimmune diseases with high dose Vit D. He has a documentary on RUclips called The LGS (leaky gut) Protocol. Worth taking a look at some of his videos and he just put out a book on Amazon too. Great doctor!
What are the symptoms of high SCFA? Probably obese yet low blood sugar people, because SCFA trigger GLP-1 which secretes insulin but are also SCFA are associated with high firmicutes (=obesity)
Would someone without a colon (ileostomy) benefit from taking butyrate supplements? If so, which type (sodium, sodium potassium, mag calcium)?
Hi Bee, As you know, Once a person has had a portion of their colon removed, it changes everything. My initial thoughts would be that they would have very limited benefits- the same with probiotics. I have not seen research that shows one way or another.
@@DrRichardHagmeyer thank you for the swift reply. I was hoping that a supplement would help with inflammation of the small intestines and also systemically... Can't seem to find anything that helps with that. 😔
But yeah, it's been really tough figuring out my health pre surgery and even moreso post colectomy. You're right about how having the colon removed changes everything and there's barely any research about it. Does your office have experience working with people with ileostomies (including the nuances it causes systemically)?
Bee my pleasure! Wish I had more info for you. It’s unchartered territory and becomes a lot of trial and error. I do have patients who have had surgery. I would focus on following an ant inflammatory diet as well as identifying nutritional deficiencies- this would be one of my major concerns if I was you.
There is lactic acid bacteria in small intestine and helps for small intestine problems search vsl 3 and other probiotics , some bacteria can be benefitfull for small intestine also , you still have stool exit so you still have bacteria there also you are fermenting food by digesting it so bacteria still important
@@han436 I have sibo, so taking probiotics can cause more issues than help... But I appreciate your suggestion and your comment! 🤗
I took a butyrate supplement in the evening and then I woke up in the middle of the night with my gut feeling like it was on fire. I felt like I had the worst fever I've ever had, but it was in my gut. I waited a week and took the butyrate supplement again and the same thing happened. Have you ever heard of this happening and what do you think may have caused this reaction? Thanks
Doesn't look like he answered. Shame. What else was in this supplement? It may not have been the butyrate, it may have been mixed with a concentrated spice like cayenne pepper or a fermented food.
@@DrRichardHagmeyer😂😂
Never heard of that- sorry for late reply. I use butyrate ALL the time with patients. Did you purchase your supplements off of Amazon or from your doctor? I don’t ever recommending buying supplements off of Amazon.
@@DrRichardHagmeyeri did get a butyric ácid, how i can take it ? In the bottle said it is dangerous it needs to be handle with special materials and a gas masck .
Butyrate can effect sleep wen taking too much, it produces b vitamins that can give u a lot of energy
Which scfa for cats
Would it help in multiple sclerosis?
Anna Moros if your SCFA levels are low then you need to get your levels up. Short chain fatty acids are so important for gut health and overall metabolic health as well. They regulate many aspects of health.
@@DrRichardHagmeyer How to calculate them ?
Is propionic acid harmful for the brain?
That’s an interesting question, what makes you inquire?
www.nature.com/articles/s41598-019-45348-z
PPA interacts with brain cells via G-protein-coupled SCFA receptors including GPR4129. Since PPA (3 carbons) is the most potent activator of GPR41, and due to the prevalence of Clostridia spp., Bacteriodetes, and Desulfovibrio spp. in ASD microbiome and its association with elevated PPA and gliosis30, we hypothesize that elevated PPA may tamper with neural cell plasticity and differentiation in vitro leading to gliosis, increased inflammatory profile, and disturbed neural connectivity, similar to ASD.
@@DrRichardHagmeyer I'm trying to help a child with ASD and came across PPA the other day and it seems to be very prevalent in people with ASD. Do you think a healthy ketogenic diet would reduce PPA or have you any suggestions on how to reduce it.
The concern I have on ketogenic diet would be the impact it would have on the microbiome. Lowering PPA might not be expected or hoped for result on keto. PPA is only one SCFA. This child needs testing before implementing such a restrictive diet. I would Also be concerned about prior nutrition and mineral status. Kids with Autism have many considerations. The study I referenced shows neuro glial inflammation with elevated PPA- but that does not mean this is what is happening with your client- Test! Test! Test! Without testing you are playing the what if game and only treating symptoms. You will want to focus on the dysfunctional physiology.
Do you have any sugestions for people who have been diagnosed with sibo who don't swallow pills whole
Powdered supplements, work on esophageal motility, juicing
My cat 😢