The Biggest Challenge in Medicine with Neil deGrasse Tyson & Dr. Linda Malkas
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- Опубликовано: 13 май 2024
- Why have we not found the cure for cancer yet? Neil deGrasse Tyson and co-hosts Chuck Nice and Gary O’Reilly explore paradigm shifts in cancer treatment, molecular biology, and a promising new cancer drug AOH1996 with City of Hope cancer researcher Dr. Linda Malkas.
What is cancer? Learn about how cancer actually works and why it is so damaging for the body. Why do cancer cells continue to mutate? Discover the micro world of DNA replication, molecular targets, and sliding clamp proteins like PCNA. Why is it taking so long to find the cure for cancer? Are institutions keeping the cure from us?
Learn about different strategies in developing cancer therapies, how FDA testing works, and how every cancer has a unique molecular signature. Learn what AOH1996 does that shuts down cancer cells and where it is in clinical trials. Could we one day use precision medicine to treat each patient's unique cancer?
How many cancer cells does a healthy person fight off per day? We discuss immunotherapy and how medicine is moving away from a single-drug solution. Will there ever be a silver bullet cancer drug? We explore new hope in cancer research and the promising future ahead in personalized medicine.
Thanks to our Patrons Willie Bass, Nicholas A Jones, Edwin Goel, Joe Gibbs, Shane Alexander, Keith Goodman, and James Kuntz for supporting us this week.
NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free.
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About StarTalk:
Science meets pop culture on StarTalk! Astrophysicist & Hayden Planetarium director Neil deGrasse Tyson, his comic co-hosts, guest celebrities & scientists discuss astronomy, physics, and everything else about life in the universe. Keep Looking Up!
#StarTalk #NeildeGrasseTyson
00:00 - Introduction: Cancer Research
2:25 - What is Cancer?
7:58 - What is AOH1996? DNA Replication & PCNA
14:28 - Why Haven’t They Found The Cure Yet?
18:29 - Shutting Down Cancer Cells
23:55 - FDA Clinical Trials
25:30 - Molecular Signatures & Precision Medicine
30:32 - Immunotherapy & “The Cancer Gene”
33:52 - Medication Half-Lives
36:45 - The Move Away From Monotherapy: Combination Treatments
42:09 - Cancer Cell Evolution
44:23 - The Future of Cancer Treatments 
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Where do you see cancer research in 5-10 years?
Without profitable treatments for pharmaceutical companies, regardless of any breakthroughs, it will be in the same place.
Helping people without pecuniary remuneration is bad business.
@@ZeroOskullol hilarious how you made this comment, yet this very same concept is address on the video around minute 15.
Try watching the video next time dunning
@@Jackiee_Chann Hilarious how I made this comment and the pharmaceutical industry is profit driven. Yuk! Yuk! Yuk! Waa-haa-ha-ha!
Hilarity ensues!!! So funny!!!
The video mentions it so I shouldn't be concerned! Guffaw! Hee-hee!!!
@@ZeroOskul my apologies for assuming you had any sense whatsoever. You can continue to be unstable I’ll see my self out. Take care , seek help
When I studied biochemistry in the early 90s, nearly all my professors felt by this time chemo and radiation would be rare treatments. Sadly they are still the primary treatments so, in 5-10, we'll pretty much be right where we are now.
My dad was diagnosed with anaplastic thyroid carcinoma (73 yo). Of the thyroid cancers, it's pretty much the worst with a 2% survival rate. His tumor was wrapped around the carotid artery and pushing up against his esophagus to almost perforating it. There were also a few spots in his lungs where it had metastasized. He was given more or less two months to live. Regardless, he started on radiation and chemotherapy. He then tested positive for the new gene therapy medication and started on that as well. This was all back in February. His latest PET scan showed zero tumor anywhere!! He's with us celebrating the holidays, which no one thought possible. It absolutely was not an easy year for him, nor is it still. The cancer drugs and treatments all did their jobs, but the side effects are brutal. He still has a long road ahead.
My mom (60 yo)had a terrible back pain that left her unable to walk. Turned out it was metastasis from the primary breast cancer she didn't know she had. The cancer was actually one that is very treatable, but no one gave her any chance at that late stage. They radiated the metastasis, started her on hormone therapy which has very few side effects, and 2 years later she is walking without any aid, cancer in total remission.
I am basically in a country some people would call third world at times, so she did not have top notch medical treatment. If she got better, I can only imagine what is possible out there.
Anyone saying there is no advancement is dillusional, especially the conspiracy theorists. This is incredibly hard, but there are tons of incredible people working on it, and, like everything else in science, it will take just one breakthrough somewhere where we never thought of before, or just skipped or overlooked.
@@badbasicsounds like my stage IV story. Awesome ✊
That is such an awesome victory! Celebrate every moment! I'm grinning from ear to ear after reading it!
Shoutout pops
Very much blessed. Cherish your pops everyday you can :)
This was the longest I’ve seen Neil and Chuck be silent while the guest talks. Bravo to all!
Lol
Thank God for that the comedy gets old
Well I thought they were about to fall asleep
I think it would have been nice If she had some sort of visualization, I lost track after 5 mins…
@@tamasbodnar1729Most people get bored and lose interest in long dialog. Think a wall of text. Neil hss said his goal is to get science to the layman, not just those deeply inteterested in it. Comedy is a method to keep interest to those who otherwise would be disinterested.
Thank you so much Dr Malkas for your work. I have Stage IV cancer and you give me hope for young people in the future. I am so grateful for all the hard work cancer scientists do.
Good luck to you, I hope you get the best care and are in minimal pain 🙏🏼
Praying for you - big hugs
Sounds like we just listened to a possible Nobel prize winner in Medicine. Excellent program!
Because cancer eats what we eat..... SUGAR
I am a cancer survivor and work for a cancer nonprofit and Linda broke down the most complex concepts into understandable descriptions (shower curtains and cocktails). I am blown away by your research and how you can describe it all. It did keep all 3 of the other smart guys quiet for a LONG time. Fascinated!
Not many episodes does the crew just sit quietly and listen. Speaks volumes about what we are learning here.
They stayed quiet because she talks to much.
Watch how many more times they have her come back.
Next time they will think twice befor they bring her back.
@@atmphil1wtf
@@atmphil1”too” much… remember this is a scientific program and yet even auto correct didn’t save your ignorance
My husband died 7 years ago from cancer. Most important is proper ID of the cancer. I read so many papers and he endured so many treatments. Some I was most afraid of were the most helpful. Some were very painful and not helpful. In the end it was the proliferation rate that called the shots. It was a mathematical game all along. I hope we will someday win this fight. So many health resources would be available for other purposes if we do. We as a world live in an exciting time. As a species we have the chance to learn to live sustainably and prosper without becoming a cancer ourselves. Never before have we had the resources to do this. Today we do if we learn to listen to our better angels and control the small thinking ego greed within.
As both a cancer patient and (former) biology major, I can certainly empathize with the difficulty in dealing with people ignorant of both how it works and how medicines are developed. This effort to educate us all is both welcome and much appreciated.
Treatment options are continually getting better, regardless of which mutation you've got. My chemo regimen is relatively light in that, while it isn't pleasant, it isn't debilitating either. I'm able to work my career full-time and otherwise (more or less) live my life as I see fit, and my disease, despite not being caught until stage 4 is, at least for the time being, stable. Also, Dr. Malkas isn't kidding about platins being rough; my primary treatment included 6 months of oxaliplatin, and 2 years later I still have neuropathy in my fingers that appears to be permanent.
Great discussion!
“How it works” is people make billions off of cancer, maybe trillions even. I personally know people that have traveled to Mexico, paid 10’s of thousand’s of dollars and are still alive and well. When i ran into a friend that was convinced he was going to die, i was speechless when i saw how healthy he was.After having chemo and who knows what else done to them in the US with no success. To anyone that has lost hope, lookup “alternative cancer treatments” in places like Ensenada, BC Mexico.
Dr. Linda Malkas is extremely impressive. Very interesting and highly well spoken. Absolutely one of the best interviews on this program. Thank you StarTalk for bringing in this charismatic expert. Wow. Great episode to everyone involved. 👍👍👍👍👍👍👍👍👍👍👍👍
DO YOU WORK WITH HER?
PLZ LETS BE OBJECTIVE HERE.
Either working w. her, or just outright pulling our leg!
This lady is such a genius. Dr. Malkas spends half her time in attempts to simplify her words enough so that even one of the premiere minds on the planet (Dr Neil deGrasse Tyson) can fully comprehend. What an amazing woman is she. But what impresses me most of all is that Dr Malkas truly gives a damn. God Speed to Dr Malkas and the City of Light cancer research team in finding a cure.
must be a joke.. I had to stop the vid because she was so hard to litsen to.. Never gets to her point and just blabs gets off topic to start talking about another topic etc.. Very hard and frustrating to litsen to. Like conversing with someone on speed who continually switces talking points with ever finishing the original talking point..@@verbumsat
Dr. Linda Malkas was a great guest. And all three hosts asked excellent questions. One of the best episodes.
FOR A LAYMAN THEY WERE NOT BAD,WOW, AMAZING,REALY,
PLZ
Im still waiting for her to say something worth while
MEE TOO.@@monicacoyle3760
I have stage 4 ovarian cancer. I am with City of Hope. I have been being treated with a cocktail of 3 different drugs, but have had to go off of them for now as my heart was starting to have issues. My CA125 was going down and my ascites cleared up. I’m hoping I can get back on treatment soon, but the heart issues are worrisome. I was so impressed with this doctor and what she shared. Please have her back again soon.
Prayers you win the battle 🙏
@@StinkyTrump4Prison Thank you. And it is a daily battle with a monster called cancer.
Great interview, Dr. Linda has a great sense of humor, and a creative mind. My wife had breast cancer, it was caught very early she is cured. Still, I quietly worry that she will get cancer again. People like Dr. Linda are helping people to live full lives and that gives me hope.
You need to start METABOLIC therapy, cut out the carbs immediately! Look at Dr Thomas Seyfrieds work. The cancer treatment industry is huge for pharmaceutical industry, they do not want to develop a cure and have no interest in funding a natural cure. Metabolic therapy is scientifically proven and It drives me insane that hospitals just give you tons of drugs which drives your blood sugar up and feeds the cancer even more! You need to go on strict keto (less than 10g carbs a day) and do OMAD and even a very long prolonged fast if you have some extra bodyweight. If you want me to explain more I am more than happy to, I have read countless books and spoken to PHD researchers for my mum who also has stage 4.
@@Jjengeringlol; why would someone like you watch a video like this? How many people died eschewing actual treatments because you spill falsehoods like this?
Neil, you should have interviewed Dr. Thomas N. Seyfried. He is Professor of Biology at Boston College, and received his Ph.D. in Genetics and Biochemistry.
He has over 200 peer-reviewed publications and is author of the book, Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer.
This guy gets it.
I hope you have Dr. Linda Malkus back. She is a wonderful teacher about cancer research. Keep us updated on this important research and get us more complete data with visual aids for in depth understanding. She should have students presenting her research in her own podcasts. Thank you so much for presenting this wonderful scientist. Shalom.
AI IS AS GOOD AS THE INFORMATION IN THE BOOKS,SHE JUST GOOGLED IT,PLUS ASK CHATGPT!
She is doing a great job communicating complex topics. With her analogies I understood most of the concepts. Love this talk.
i agree. even for me im not that good at english but still i understand what she was saying
Thank you Neil. My daughter was diagnosed with Fibrolameller HCC in August of 2019. flHCC is an ultra rare cancer that starts in the liver. She is 1 in 5,000,000. It is so rare that there is no standard of treatment other that to do surgery and hope you get it all. Liver surgery of this type is a grueling procedure that takes a minimum of 6 weeks to recover from. The median age for flHCC is 23. My daughter was 23 when diagnosed. A 9cm tumor was removed during her first surgery. Almost50 percent 8f her liver was removed. A year later her scan showed new growth. Surgery was done again and lymph nodes were removed. 3 months later scans showed two new possible spots and surgery was done on the non lu g spot. That turned out to be a false positive but still required 6 weeks to recover again. One more surgery was required to remove stitches that did not dissolve properly. She has now been NED - no evidence of disease for over 3 years. Obviously we all hope these good scans continue forever but this has a nasty habit of coming back as many cancers do. This AO-1996 sounds like a winner.
Thank you for raising awareness about this drug.
This topic is such an important one because the disease impacts so many directly and indirectly. I’m currently writing a book about cancer and the use of an anti parasite drug you can buy online that’s seems to be helping some people with cancer heal. I was happy to hear Dr Malkas flat out say the truth, that cancer is a parasite.
Another point I’d like to share…. One of the things I love the most about StarTalk is the humor. Big fan of humor. Cancer is a more difficult topic to pull off humor with if you put yourself in the position of someone who has it and is listening. I didn’t feel like anything crossed the line and I’m not criticizing or complaining. I’m simply sharing that cancer is diabolical and that shooting for a laugh while talking about it is a lot like walking a tight rope in a windstorm.
Thanks again for all of your work in bringing fascinating and potentially life changing topics to the world StarTalk team!
Linda, thank you for your determination, knowledge, and forward thinking. I lost my mother in 2015 to breast cancer--I don't wish another woman out there to have to go through what she went through. I look forward to watching this research evolve and bringing forward better treatment.
Yesss!
THEN SUPPORT HRT IN POST MENOPAUSAL WOMEN,IT IS CRIMINAL TO DEPRIVE THEM.
STUDIES SHOW CLEAR BENEFIT .
GOD LESS.
Lost mine to triple neg breast cancer April 2015
Lost my daughter to triple negative breast cancer in 2020.
One of the best interviews I have ever seen in years!!
It just moved me to learn and do more to help patients and caregivers.❤
SO NICE,IT TOUCH MY HEART.
ASK CARE GIVERS HOW THEY FEEL,
YOU WORK WITH HER DONT YOU ?
YOU ARE MISGUIDED IF YOU CAN BE MOVED BY THAT
MISGUIDED LADY.
@@moshegoldsmithI see you are criticising others in this forum for expressing their hopeful regard to this Doctor. I would like to hear you use that BIG MOUTH OF YOURS AND EXPLAIN YOURSELF?
WOW VERY CONSTRUCTIVE,PRODUCTIVE,TRANSFORMATIVE CRITICISM ,YOU SHOULD HAVE A COLUMB in New York Times ,it is no wonder that this Chanel does so well, viewers like you will believe any thing.@@Alithios good luck to you.
Thanks for this interview! It was amazingly interesting. Linda was amazing: I think a professionost and an expert in a field as complex as molecular genetics being able to clearly answering to these questions and breaking concepts down in a such comprehensible way deserve praises!
This is one of the best, most informative of your short videos I have seen, and the best short video I have seen on cancer. Thank you very much for this, and please continue with videos that are not directly physics videos, but are on important topics.
Never been so happy someone’s dream didn’t come true. This was very informative and I am so glad her team is working on this. even if it doesn’t work and it prompts someone else to just think differently going forward then they’ve done a good job.
SURE WASTING MILLIONS OF TAX DOLLARS
TAKING 20 YEARS
TO DISCOVER NOTHING AND FIND OUT THAT THE PROTEIN THAT WAS DISCOVERED BY HER AI
COMPUTER WAS IN KIWI ? GREAT JOB DR.
@@moshegoldsmithSo it's money you are worried about? I am still alive after 5 years of fighting S4 cancer thanks to the millions of dollars invested in this quest. Most effectively with immunotherapies. Cancer diagnoses are growing more than ever. Take care not to stress yourself with mindless anger and catch a case yourself.
I am already a cancer survivor. I had a cancerous polyp removed from my colon two years ago. My son-in-law just passed away two weeks ago from a brain tumor his 5 th, and another friend of our daughters is about to pass away from cancer that just got out of control in the past two months, thank you for giving us a glimpse into the future of a cure❤❤❤❤
Dang, where do you live? Environmental? Hope you the best and sorry for your loss.
Look up biofilm
Am I wrong if I said they're a lot of cancer case in the USA? "Food, environment,.."
THE CURE IS NOT IN THE MEDICINE,
HIS CANCER STARTED MANY YEARS AGO IN HIS GI TRACT,TRAVELED TO HIS BRAIN VIA LYMPHATICS SYSTEM.
IF DURING ONE OF HIS PHYSICAL
THESE TESTS WHERE DONE;CRP,IGF1,TNF ALPH
OR HOMOCYSTEINE ,ALSO HGB A1C.
IT MAY HAVE DETECTED IT EARLY AND HE WOULD HAVE BEEN WITH YOU.
GODBLESS.
MEDICAL COMMUNITY DOES NOT KNOW ANY THING ABOUT CURE,BUT THEY KNOW HOW TO MAKE MONEY.
@@acidkhmerAccording to google if you are over 66 expect to get cancer. It is mainly age related.
Sir
When it will be available in India
You're an exciting group speaking of something that makes sense to me. I think it would help me to have more space to speak from. I spent most of my life being too shy or timid to speak in front of strangers so, attempts resulted in the energy feeling hostile or no nervous. Now I speak inwards to my guts, and the more I do, the easier I feel about talking in public. So yes I'd love to test my senses with folks who are interested, too.
I also hear differently than others and that's how my family talk too, so it isn't just me.
I hope to find local interest in hearing from me for the purpose. I think I'd be cured of little scars inside.
I loved it to the end!!! Such an incredibly intelligent person and scientist to bring to the show. Thank you.
BUT YOU ARE NOT GOING TO LIKE THE ENDING.
A good friend of mine died 4 weeks ago after his cancer was accidentally discovered in June, and all that science has to offer proved unable to reverse the rapid course into fatality. He worked in evaluating health services on an international project and discussed the developing process on a peer basis with the professionals, and donated his remains to science. May some good come of it!
Very sorry you lost your friend
My mom died of a COVID-19 / cancer combo. If it wasn’t for the Covid, they would have never thought to check for the cancer, by then it was too far advanced.
@@lavajunkie sorry
In my opinion he was associated.
Money from treatments stops the cure
as a cancer patient I would say it would be wonderful to speed all this up a good bit!
I think I once read that neuro cells could reproduce, but the regeneration cycle of those cells is longer than we live. Also I think I learned that cancer cells reproduce very quickly. It sparked an idea that if we were able to harness the regeneration power of cancer we may be able to treat neurological issues. Is that crazy?
Thank you for this episode. My mother was diagnosed with Stage IV Lung Adenocarcinoma last 2018, the past 5 years has been quite a struggle physically, emotionally and financially.
I hope we can find a cure soon so we can spare many lives from suffering.
If you don’t mind me asking, lung cancer kills most very quickly after diagnosis….What kind of medical approach did you guys take?
Have you tried looking overseas for treatment? It's far more affordable. Medical systems these days are the same across the globe, so there isn't much difference between USA treatment and treatment in Greece or France or somewhere...
THE CURE IS IN THE HANDS OF HER CHEF
NOT DOCTORS.
HOPE,HAS NOTHING TO DO WITH IT .
AS LONG AS ORGANIZATIONS LIKE AMERICAN CANCER SOCIETY ARE SUPPORTED BY MEAT,DAIRY, SUGER,AND FOOD INDUSTRY CURE IS A PIPE DREAM .
GOD BLESS
One of the things this Talk helped me understand is why 'the same' cancers affect people differently. The discussion about the host condition was really pivotal, as it helps to provide a context for the rate of cancer spread and adaptation. It was also helpful to understand the analogy of 'carpet bombing' versus 'precision drone missiles' to attack the cancer cell network. The logic behind the new drug is amazing, and I am very thankful that this information was shared via the channel in such an accessible way.
WOW HOW insensitively DESCRIBED.
IT REALY MAKES ME FEEL BETTER FOR THE PEOPLE OF GAZA ,HIROSHIMA ,NAGASAKI, OR DRESDEN ,
SHE IS A MINDLESS BLONDI, WITH FILLER INJECTION ON HER LIPS GONE WRONG.
NO DISRESPECT TO MARYLYN MONRO
OPPS SHE WAS NOT A TRUE BLONDY.
stumble upon this episode due to algo, so glad I gave it a watch. this is probably the easiest piece of content to digest on cancer. thank you all for making this and sharing the knowledge!
Great episode, thank you for hosting Linda she is an amazing human being. Thank you Linda for staying curious and being creative with your problem solving skills in this import field of study. Looking forward to see the results published from your clinical studies.
I love Star Talk and this was immensely interesting. My father battled cancer for several years but sadly passed away 2 years ago. Even though cancer is a serious thing, I really like that you put some humor in there. Keep up the good work!!
18:15 Spite is great kindling, but passion is the fuel of success.
Very informative and helpful. Thanks. Wish there was more seriousness this conversation and Dr.Linda was given the respect she so deserves. There was no need to make uncalled childish comments and making this difficult subject a casual chat. If you can mute the conversation of the other 3 gentleman and listen to Dr.Linda its a very interesting and informative conversation.
Thank you for informing about cancer from the somatic theory perspective. My suggestion would be to invite Dr. Thomas N. Seyfried and have a talk about this subject, to show another perspective to manage cancer. Love your show by the way, always get a blast - but when I see misinformation I have to react, at least hear all sites of this subject so people can figure out themselves. In my mind you need to treat the core of a problem to solve it, not the symptoms or the downstream effects. All that being said, I absolute admire anyone exploring treatments for humanity.
So I have melanoma with a BRAF gene mutation that we’ve been treating with a combination of targeted oral chemotherapy and immunotherapy for 3 years now. We just started genetic testing to find the “fingerprint” of my cancer and I’m really excited to be a part of this new method of detection and treatment. Cancer research has come a long way in the last decade and while we still have a long way to go, I’m excited to see what we will learn and how treatments will progress over the next 10-20 years. This episode of Startalk was super interesting!
Good luck to you.
Wow my daughter attended Queens College. Her son, my grandson goes to Townsend Harris High School which is on the Queens college campus.
Theoretical physicist Michio Kaku still teaches there. I was privileged to attend one of his lectures.
Thank you for the perspective. You can now do a show on the funding that goes into cancer research.
Star talk Linda was an absolute delight I wish more people would have that care in what they do we may just have that cure with more people like her thank you Neil you have been a force for keeping science cool
CURE FOR CANCER IS DISCOVERED 30 YEARS AGO ,YOU JUST DONT KNOW ABOUT IT ,SINCE IT IS NOT GOOD FOR BUSINESS.
Love the explanation by Linda and happy to witness the groundbreaking progress of cancer treatment.
Thank you so much Dr. Linda for sharing such a complex subject. My hopes on humanity is much higher than ever.
Thank you fo this excellent special edition. It gives me hope and helps me cope with my daughter's fight.
Very well explained👍 Let me proffer another complimentary explanation. Cancer is not a "disease" its a myriad of diseases that occur when the mechanisms that control cell proliferation go awry. Though some cancers share some mechanisms, the fact is that there are a myriad of possible mechanisms that may or not be happening at the same time, in effect most tumors like people are their own little personal malignant cosmos in their own self! To make things worse, as the presenter pointed out, every generation of tumor cells is different and thus may have evolved a new particular way to evade therapy, in effect, evolving to live another day! Luckily, some malignancues evolve slowly or not at all and are thus perfect targets for targeted therapy. Chronic myelogenous leukemia being a perfect example, but for most common malignacies (carcinomas or epithelial dervided tumors) that is not the reality. Targeted therapy which began decades ago with tyrosine kinase inhibitors has a long way to go and, even when successful, is most often not a magic bullet.
Cancer genomics makes rocket science seem like a kindergarten activity 😬
My dad went to city of hope and they helped him with his double expresser B cell lymphoma. He improved for a while unfortunately there were some other stuff going on he wasn’t able to over come a few years after. City of hope is amazing!
This gives me so much hope for the future. I lost my wife 4 years ago at age 46 from cancer. Deadpool summed it up perfectly: The worst part about cancer isn't what it does to you; but what it does to the people you love.
How much does it cost to produce? After availability this is most important.
I applaud you for discussing this on your show. Cancer and hope are hard to put together. This provides some hope.
Thanks for the episode is best if you interview professor Seyfried on cancer as metabolic disease. He is amazing. Help to spread his message as well please ❤
Also Dr. Michael Levin. He has a more fundamental understanding of cancer and is doing incredible research. His approach is to work with the bio-electricity of cells. Really mind blowing. It would be great if all these scientists would work together and share their discoveries.
Dr frank shallenberger Nevada
What a wonderful video! I have recently been diagnosed with pancreatic cancer, and am now on chemo and very whacky blood sugars along with long-term cardiac issues. I hope someday Linda will receive the many prizes she and her team deserve for this great work. I just subscribed to StarTalk. Thank you, Neil and all for putting this on.
My husband has stage 4 metastatic progressive cancer with a Gleason score of 9. He’s had cancer since 2010. Recently we were given the option of Hospice or Pluvicto. In order to do pluvicto your kidneys must function at 30 and above. His kidneys are functioning at 20. Any advise?
❤😂 I have a good friend that has breast cancer and I've learned so much from this episode of Star Talk I want to thank you thank you thank you!😅😅😅❤❤ this is the best show you've ever had and probably ever will to anybody that has anything to do with cancer and the future of any other molecular designed and or repaired disease
I am a stage 4 cancer patient currently fighting. How can I ask about trial information? I was diagnosed five years ago at stage 4 with Gastro-intestinal stromal tumors or "GIST". Its a rare type that affects less than 5,000 Americans a year from what I'm told. I am in my early 30s and am somewhat of a medical oddity. Usually this disease affects people 60 plus. Ive only seen one other mid 30s male in a study for gist. I am currently on my fifth line of defence and have had a whipple surgery two years ago with a partial liver resection. The primary location was extending off the duodenum and was 7" when they removed it with 3/4 of my liver, the tip of my pancrease and a bunch of other stuff. Several months ago we discovered it has matastasized to my bones and ive undergone targeted radiation therapy twice for 9 locations in total now. I basically am playing whack-a-mole with radiation beating back tumors that pop up. When Niel and the Doc were talking about cancer resistance I had a very personal acknowledgment of how smart and evasive this disease can be. I am currently on TKI inhibiters which was also a moment of recognition for me when she mentioned them... ive been on four LOL! I actually have a scan im not looking forward to this Friday and am not expecting great news. I would love to inquire about the possibility of being a good candidate for the trial. I have already been on two trials. One was prior to FDA authorization. How can I contact Dr. Malkas? Thank you in advance!!!!!
Great show Mr. Tyson! Both guests were great with great questions! I would love to hear more from Dr. Malkas as she also knocked it outta the park!
Save this video and take to your Dr. They can help point you in the direction of how to potentially sign up for trials.
I'm into this I was recruited to molecular biology early on before I settled into FNP. Let's listen
Fantastic episode. Let her talk without any interruption and man that was enlightening! Thanks!
This is an outstanding episode of StarTalk! Kudos to Chuck and Gary on great questions.
OOPH GUYS, PROFOUND COMMENTS!
YOU CAN DO BETTER?
I’m about 15 minutes in and the look of interest with what the guest is saying on all three of them without goofing around with the guest lol is so rare lol this guest has them hooked on the subject of DNA , it’s so interesting
thank you for giving me and others hope bless you
One of, if not the greatest "dumbing down" explanations that I have ever heard about a subject that I definitely need a "dumbing down" explanation for! Yo StarTalk, thank you for Dr Malkas, and Star Talk!
A great video and the fact that Linda spent so much time and research on testing and finding the area in cell that drug companies had already said could not done. She must be acknowledged as being a great scientist.
HALF-LIFE is very important in medicine. I’ve been on tegretol for thirty years (for epilepsy), and I know very well the times of day I have more or less seizures. I’ve designed my med schedule around my medicine’s half-life to great success compared to when I did not do this.
They are only interested in TREATING the epilepsy symptom, not remove the cause of epilepsy from your brain. I wonder how much total money you and your insurance company paid the pharma company over 30 years. Shame on big pharma and medical science.
Respects to for you having arrived at optimal scheduling, that's applied science. I think StarTalk could do a full episode on half life in biology. It's part of pharmacokinetics, and is not so straightforward as in nuclear physics. As with many others I have to avoid grapefruit because it stretches out the half life of medications as well as caffeine.
I did not know that about coffee. But I do think many different kinds of doctors would benefit their patients by working closely with nutritionists to decrease the pharmaceutical reliance and increase the overall health of the body and how it functions
What about Dr. Burzinsky from Texas ?
That Dr was found to be a conman making money off desperate people.
@@vincentwiese8414 are you crazy ! He still practicing to this day ! Has his own clinic AND FDA cant shut him down cause he has success. Go look at the documentary and a lot of stage 4 paitents that traditional medecin couldt help well he was able to cure their cancer ! And who wants to cure cancer when its a money making machine !
Excellent guest and episode
I lost my mom to cancer. I have a treatable form of it., skin or melanoma. But, I may get ripped for this, darn she's pretty! I had to say it, even though I watched the entire video and appreciated the info. But yeah, I loved listening to her. Thanks StarTalk. I couldn't help but compliment her. And I had to add this... what a great speaker!
Go Mexico, Tijuana
Some people are immune to cancer. Immunotherapy such as it exists, is highly effective. It seems like the future of cancer treatment is the future of teaching immune systems to battle cancer before it happens.
Ditto!
Medical mafia never cure cancer metabolic problem cure found over 100years ago
would it maybe help find cures/treatment for multiple scolirosis
Good initiative, very informative #love from 🇬🇧
One of the best interviews I have watched.
Wonderful, wonderful stuff - lady & gentlemen - and Chuck. ;-) Thank you so much for spreading and sharing the knowledge!!
This is the best science / entertainment show ever.
I’m sure it’s able to captivate a High School science class
Sir, where did the number "8" as in cancer cells a day come from?
Wish this had come a year early 😪.... but happy for all the lives that will be saved 💯💯💯
As someone who has family currently suffering from cancer and family who died from cancer, many blessings to you and your family for the work you do.
BLESS THE ONES THAT FOUND THE CURE
AND TOLD THE MEDICAL COMMUNITY
AND THEY WERE KILLED OR DISAPPEARED.
FUNCTIONAL MEDICINE DOCTORS
WE CURE CANCER,DIABETES,HEART DISEAS ,PARKINSON'S, ALZHEIMER'S,, MULTIPLE SCHLEROSIS,LUPUS ,ETC ETC, EVERY DAY.
correct me if I am wrong. But cancer cells always change stuff (e.g. switch off and on certain enzymes or proteins regulating growth/cell death). Some of those changed cells just have a disadvantage on other cells, unless chemotherapy (compounds like Cis/Carboplatin) are introduced. Then suddenly these have an advantages and that is the reason the cancer reoccurs. Even that is the reason for mixed responses, where you have cell clusters (metastasis) that grow despite the rest of the tumor mass is receding. Targeting a pathway with so many allyways for tumor growth sounds really interesting! My question would be if any cancer (brain, liver, lung, breast etc) can be targeted with AOH1996.
Could you talk about this new is it sonic or ultrasound technology that is being used for liver cancer?
I'm dying of 2 kinds of cancer and I don't think I'm going to see a cure. It's been fun watching your show. How come Xtandi cost $32K a month. I'm going to die early cause I can't afford that.
I wish for you the best , honestly
Watch Jim bruer's podcast episode 110 . With Kevin Henning, he had stage 4 cancer and 1 month to live . He took a dewormer from brazil and cured his cancer in 14 weeks . It's banned in America because exactly what these guys in the video were joking about . It's cheap and big pharma and the government can't make money off of healthy people. Look into what I'm saying you might be surprised
It's called fenbendizol or fembendisol I'm not sure how to spell it but it supposedly can cure cancer because it's believed that cancer is parasitic. I wouldn't even say this if I didn't think it was true, look up the video I told you about watch it and then you can make your decision. I hope this helps
If I had it I would give it.... Wishing God's blessings for eternal life!
Are you familiar with proton therapy?
I. Hung.On. every. single. Word 🤯 . Marvellous 👍🏾 truly marvellous edition 🇬🇧
Thank you Ms. Linda. All the best!!
In my opinion this is possibly one of the best episodes of star talk. Great work!
This was a lovely stand out video
35:38 I will always take my meds on time :p
what an episode 🤩
And now you know....😂
Very informative. Thanks for this commentary.
Wonderful insights. Had 2 recent surgeries for tumors. The technology will continue to improve, and I am hopeful everyone has access to treatment.
Thank you for this video, people!
Great and informative talk. I'm excited to hear about these new treatments. Keep up the good work Linda!
keep pioneering for knowledge and improvement, I suffer with multiple scolirosis and take anything like this as important
This is so interesting and much more accessible than I thought it might be. She has a great way of explaining things.
Thanks star talk
Divergent thinking is important in the creative process
Wonderful Blessed information Thank You ❤
I am a patient at City of Hope. I am on my second clinical trial there using immunotherapies, which have gotten me into remission 3x.
Classic Hodgkin's Lymphoma, refractory to standard first and second-line treatments.
That is wonderful! My prayers for your continued good results and health.
Excellent and informative video! However, cancer is such a multifaceted and complex malady that finding a "cure" will probably always remain illusive. I hope that the clinical trials for AOH1996 go well and that it gets FDA approval soon. Good luck Dr. Malkas! 👍👍
You are trying to explain it or have an opinion when an expert is discussing it is laughable.
You are a nobody, know your place.
What a great interview with this amazing researcher. My grandfather was one of the first cancer researchers back in the 1930’s. He would be so thrilled to see the progress that has been made in this field.
Bravo Dr. Malkas! Amazing
Wow, that was interesting! Thank you!
I just learned so much about that topic, cancer! …and it was fun listening.
AOH1966 was named after the initials and the birth year of Anna Olivia Healey, who died of neuroblastoma in 2006. The funds collected by her parents have helped support the development of the chemical compound
Great info! Sending thanks to and wishes for God's blessings to the AOH family!
THAT MONEY WOULD HAVE BEEN WELL SPENT
TO LOBBY CONGRESS TO STOP THESE PEOPLE FROM TAKING BRIBES FROM THE INDUSTRY
AND PROMOTE MEDICAL EDUCATION CONDUCIVE TO HEALTH NOT DISEASE MANAGEMENT.
TEACH DOCTORS TO CURE AND PREVENT DISEASE NOT MANAGE IT.. FOR GOD SAKES.
all caps are harder to READ ! :)@@moshegoldsmith besides, your message is despicable, think about it, basicaly what you are saying is that this young girl got cancer because of her lifestyle, and we should lobby (bribe) congress, not to accept other bribes, and teach young people how to prevent cancer ? please get lost, cancer is not always affecting people because of any decision they made
@@moshegoldsmith ah yes, just cure and prevent disease, it's just that easy, and if you're poor, just get money, if you're homeless, buy a house, if you're deaf, just learn to hear. Forehead 🤦🏽♂️
YOUR RESPONSE IS VERY SIMILAR TO THE REACTIONS I GET FROM ALLOPATHIC MEDICINE TRAINED DOCTORS ,BE ADVISED THAT
IGNORANCE IS NOT A BLISS. @@BushyBrowsHD
Excellent interview. Would love to discover more people like Linda. An Amazing person with such passion, determination and skill.
SURE ANOTHER CO WORKER COMING TO THE RESCUE !PLZ
Fantastic interview; world-changing work. Thanks for sharing, and thanks for the work.
wow... what an interesting and so so so relevant subject and great guest... as always... great content... Thank you
I love how she is telling this story. 🤗🤗🤗