Fanconi Syndrome - Renal Proximal convoluted tubule defect - RTA - Pathology

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  • Опубликовано: 25 ноя 2024

Комментарии • 86

  • @Ryan-jv9se
    @Ryan-jv9se Год назад +9

    This guy is not just a genius but the best teacher..I love his style. Thank you so much for all that you put into these videos Medicosis. Btw just being semantic here but tenofovir is a nucleotide not a nucleoside RTI

  • @precious-chuksstance8103
    @precious-chuksstance8103 5 лет назад +25

    Fanconi syndrome ---- generalized aminoaciduria while Hartnup dx----- neutral aciduria( such as tryptophan glutamine etc)

  • @hebahammoudi7160
    @hebahammoudi7160 2 месяца назад +1

    This is definitely my new favorite medical channel, the way you describe everything is amazing!

  • @vdoubleu-o4u
    @vdoubleu-o4u 5 лет назад +7

    Oh my gosh! I chose this for my clinical chemistry and U.A. case study and I'm so glad you covered this!

  • @patrickphilip777
    @patrickphilip777 3 дня назад

    I keep having glycosuria and bedwetting for the past year. I just turned 29 the other day. Before last year, I have not wet the bed since I was 8. I had an A1C test and it came back fine.

  • @Ask_Dr_Arik
    @Ask_Dr_Arik Год назад +2

    Super excellent explanation and very straightforward ❤

  • @Girlinterrupted955
    @Girlinterrupted955 2 месяца назад +1

    I wish you were my lecturer at university!

  • @Patsy1985
    @Patsy1985 3 года назад +3

    I was recently diagnosed with acquired fanconi syndrome due to high dose Ifosfamide chemo five years ago. Seeking out my best options right now, leaning towards Mayo.

    • @johannarubin1980
      @johannarubin1980 9 месяцев назад

      HI can I ask you how you have been treating this please? I may have this looking for answers

    • @Patsy1985
      @Patsy1985 9 месяцев назад +1

      I saw an onco-nephrologist at Mayo in Rochester, MN. She confirmed the findings and has me on a daily medication called PHOS-NAK. It’s a combo of potassium, phosphorus, and sodium. Seems to be working great. Hospitalizations have reduced by 95% since ‘21. A kidney transplant is still in the future but this should hold it off for a while.🤞🏻

    • @johannarubin1980
      @johannarubin1980 9 месяцев назад

      @@Patsy1985 wow thats great!!! May I ask how you were diagnosed? What findings were there??? Do you have a facebook or e-mail so I can ask you some questions?

  • @mubasshiramaryamkhan302
    @mubasshiramaryamkhan302 5 лет назад +3

    In Hartnup disease there'll be failure to reabsorb tryptophan and thus will show signs of (pellagra) niacin deficiency and is not associated with metabolic acidosis and other electrolyte deficiencies.

  • @nugentmichael
    @nugentmichael 2 года назад +1

    This was impressive.

  • @muhammadabdelrahman337
    @muhammadabdelrahman337 Год назад

    You're incredibly smart. Thank you so much ❤

  • @Qwerty3456
    @Qwerty3456 5 лет назад +7

    very conceptual lecture!

  • @hdh2179
    @hdh2179 2 года назад +2

    amazing job honestly you're very talented

  • @anjuchandrasekhar1740
    @anjuchandrasekhar1740 2 года назад

    Each word is a gold medal qn. In Awe. 👍👍👍

  • @The_Procrastination_Pro_101
    @The_Procrastination_Pro_101 3 года назад +2

    thank u for this video. u made it super easy .lots of love.

  • @Yan-pg1rs
    @Yan-pg1rs Год назад +1

    Hi Medicosis? When can you do a vedio about different types of RTAs? I really need it.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  Год назад

      I have it already! It was discussed in a video titled: “NAGMA and RTA”…You can find it in my nephrology playlist.

  • @dr.leelaram
    @dr.leelaram Год назад

    Great explanation dear❤

  • @rashadovchuyev2199
    @rashadovchuyev2199 5 месяцев назад +1

    Perfection!

  • @Jkawalsky1
    @Jkawalsky1 4 года назад +3

    should def be decreased skin turgor not increased

  • @arpithbhatt6133
    @arpithbhatt6133 2 года назад +1

    Great explaination 👍

  • @hadeeladham1844
    @hadeeladham1844 Год назад +1

    Thank you so much.

  • @Zain_altouka
    @Zain_altouka Год назад +1

    Amazing job 🥰🤍🤍🤍

  • @IbrahimNegm
    @IbrahimNegm 4 месяца назад

    I guess the footage in the beginning of the video is recorded in Oman, right ?

  • @shafiqkharal3351
    @shafiqkharal3351 4 месяца назад

    My son is facing this disease , want to know about the best treatment of this disease. or the best doctor for this disease.

  • @codrut913
    @codrut913 4 года назад

    One of the best !!

  • @GeralySantanaBautista
    @GeralySantanaBautista 5 месяцев назад +1

    WOWWWWWWW Thank you so much.

  • @mohamedezzat6651
    @mohamedezzat6651 4 года назад +1

    Thank you for this nice lecture

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  Год назад

    👨‍🏫 Nephrology Playlist: ruclips.net/p/PLYcLrRDaR8_d7bEi4DvucO73N4N_1vvPk

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  Год назад

    🐳 Nephrology Playlist: ruclips.net/p/PLYcLrRDaR8_d7bEi4DvucO73N4N_1vvPk

  • @irwincrook567
    @irwincrook567 4 года назад +2

    Just play him in 1.5x speed and he is the best person to explain anything

  • @ananthupadmanabhan9316
    @ananthupadmanabhan9316 4 года назад +3

    Hey! great video. Just one doubt. Shouldn't skin turgor decrease in dehydration. You mentioned it increases at 9:10.

  • @fabulosa002
    @fabulosa002 5 лет назад

    Hatnup doesn't have increased urine pH, glucosuria, and all the other urias. also phosphorus and calcium are normal in hartnup

  • @ElnaKruger
    @ElnaKruger 3 года назад +6

    Pediatricians are idiots, when they say, "this infant is dehydrated," "NO, he's volume depleted!" XD you're brilliant.

  • @sindhusutanayak7657
    @sindhusutanayak7657 5 лет назад +1

    Very nice

  • @muhammadaliaslam4023
    @muhammadaliaslam4023 2 года назад

    @Medicosis Perfectionalis
    why do we give Loop Diuretics to Fanconi Patient even though he or she is volume deprived
    just for Acidosis?

  • @imasuperkoala
    @imasuperkoala 5 месяцев назад

    What happens in an euvolemic patient with acidosis, giving bicarb will also affect K. In this case what would the reason? Because aldosterone should not be high thus the Na-K would not be stimulated. Can someone please explain. Thanks

  • @ABC-fv7ow
    @ABC-fv7ow 4 года назад +1

    Gr8.but why high K+ in urine?didnt understand

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 года назад

      Because the Na/K pump on the basolateral border of the proximal convoluted tubule cell is not working.

    • @ABC-fv7ow
      @ABC-fv7ow 4 года назад

      Thats what I am saying sir.when k+ has not entered cells from blood,how it is passing more in urine?Pls help sir.

  • @bhaveshgarg8142
    @bhaveshgarg8142 3 года назад

    Why does kidney absorbs only water incases of heart faliure?

  • @thureinzaw7779
    @thureinzaw7779 3 года назад

    Isn’t it supposed to be hyperkalemia since Na/K pump doesn’t work and unable to excrete potassium? Please kindly explain me sir.. i’m confused

  • @b2dgmedia210
    @b2dgmedia210 4 года назад

    Would you be able to recommend the best specialist in the U.S. to seek help in treating this disease? TIA

  • @srinivasaraosirasapalli5104
    @srinivasaraosirasapalli5104 5 лет назад +1

    nice

  • @BhavyaKansal18
    @BhavyaKansal18 4 года назад

    Fanconi Syndrome is not the same as fanconi-bickel syndrome right?

    • @fatemaatia4385
      @fatemaatia4385 Год назад

      Fanconi bickel syndrome is one of the hereditary causes of proximal tubular dysfunction ( fanconi syndrome )

  • @Nicu-Live
    @Nicu-Live 2 года назад

    laughed so hard when he said....pediatricians are idiots 😂😂

  • @mobenkane2075
    @mobenkane2075 5 лет назад +1

    DECREASE SKIN TURGOR , DUE TO DECREASE SKIN RESILIENCE !!!!!!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 лет назад

      I don’t understand

    • @gracecabungcal4392
      @gracecabungcal4392 5 лет назад

      he is saying .. it should be decreased skin turgor not increase...

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 лет назад

      Are you talking to me or to Moben?

    • @tiotio3185
      @tiotio3185 5 лет назад +1

      @@MedicosisPerfectionalis You said: TBNa decreased...and skin turgor increased because of decreased skin resilience...I think he was right to say decrease skin turgor, due to decreasing skin resilience.

  • @greatman205ftw
    @greatman205ftw 4 года назад +1

    dont tell me what to do XD
    im here for fanconi syndrome and anemia and dont have extra 15 mins to waste on 2nd course physiology of PCT

  • @DoctorCiaran
    @DoctorCiaran 3 года назад

    I like these videos and generally enjoy the style and humour but some times it's a bit unnecessary, "paediatricians are idiots" for example, I know it's not meant literally but it's not funny either and just encourages the confrontational vibe that already plagues interdisciplinary medicine.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 года назад

      It was just a joke. If you don’t like it, that’s fine. I completely understand.
      Thank you so much for watching! It means a lot!

    • @DoctorCiaran
      @DoctorCiaran 3 года назад

      @@MedicosisPerfectionalis I get you, I don't want to be over-sensitive, just imo sometimes they remind me of old school consultant bullying etc. I know that's not what you are going for though, and totally subjective, and your videos are obviously fantastic. Thanks for the reply.

  • @srinivasaraosirasapalli5104
    @srinivasaraosirasapalli5104 4 года назад +1

    nice