Nicotinic vs Muscarinic Receptors

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  • Опубликовано: 1 июн 2024
  • Nicotinic vs Muscarinic Receptors.
    Acetylcholine vs Nor-Epinephrine.
    Cholinergic vs Adrenergic Fibers | Neurology..
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Комментарии • 241

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  3 года назад +16

    💊 Autonomic Pharmacology: www.medicosisperfectionalis.com/

  • @richardgriggs8525
    @richardgriggs8525 Год назад +65

    I'm legit 60 seconds in and already this makes sense. My med school professors are world leaders on the ANS but can't be bothered to state the most foundational things in a straightforward way.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  Год назад +3

      Thank you so much 😊 for watching!

    • @robertbruhcuh3634
      @robertbruhcuh3634 10 месяцев назад

      they don’t know lmao it’s most people especially teachers not college some college im pretty sure actually learn what they teach

  • @cardamomes
    @cardamomes Год назад +18

    Absolute perfection. Suddenly years of lectures makes sense in one video.

  • @leobesa2887
    @leobesa2887 3 года назад +16

    Don't watch this at 1.5x speed

    • @Amerah-hs6ks
      @Amerah-hs6ks Месяц назад +1

      This is literally what I intended to do🤣🤣💔

  • @jacobbryan4875
    @jacobbryan4875 2 года назад +51

    One of the best explanations out there on this topic! Thanks a lot.

  • @grayhero1
    @grayhero1 3 года назад +22

    I'm preparing myself for my Pharmacology exam,and I watch your videos to give every topic a beautiful start,i know no means to say how useful these videos are.thank you MP.

  • @sobster123
    @sobster123 2 года назад +11

    I've *always* struggled with pharmacology. Especially this topic. But my God. The way this GENIUS explained this. ❤️I could give him my soul. The best teacher ever. Thank you *so* much Mr Perfectionist.💞

  • @ShinigamisBlade
    @ShinigamisBlade 3 месяца назад +6

    Prepping for a test and the jokes are keeping me alive 😂

  • @afifahbasirun3586
    @afifahbasirun3586 3 года назад +27

    Thank you so much.
    This is very helpful, it feels like you're slapping my brain with knowledge from my lectures but with more sense!!

  • @user-ru3pw3bk2k
    @user-ru3pw3bk2k 3 года назад +34

    We are relly grateful for u sir,plz keep going ,I like the way that u explain, u make every thing easy ...thank u so much

  • @danicahashimoto9833
    @danicahashimoto9833 4 месяца назад +2

    I never comment on videos but I have to say this is one of the most helpful videos!! Taking my boards for becoming a Physician Assistant (PA) and these concepts always went over my head. So important to nail it down for all the pharmacology and functions. Thank you for this!!

  • @sherihanalmohammad7195
    @sherihanalmohammad7195 Год назад +1

    this is by far the mosssssssssssssst useful piece of info I've found on RUclips or any other platform, with the best way to put it out
    wow, I still can't believe I've found you!
    Thankssssssssssssssssss

  • @KyleRayner12
    @KyleRayner12 3 года назад +8

    Thanks for explaining. You covered this better in 0.25 hr than my professor did in 1.5.

  • @oliviam1999
    @oliviam1999 3 года назад +7

    thank you so much for explaining clearly, i love being explained to like i know nothing because i really know nothing

  • @rashialimbona1078
    @rashialimbona1078 Год назад +2

    This is the first time I've watched your videos and I love it already. New subscriber gained!

  • @romuellebarbado2088
    @romuellebarbado2088 3 года назад +4

    watching this before I take my quiz and it really is a huge help. Thank you sir

  • @Shambhaviak
    @Shambhaviak 3 года назад +6

    Thank you so much!
    This was such a comprehensive and informative video
    I learnt the topic well :)

  • @depharmily2064
    @depharmily2064 3 года назад +7

    THAT WAS FUNNY AND INFORMATIVE , THANK YOU SO MUCH, MUCH LOVE FROM SOUTH AFRICA

  • @shadowkokufu9178
    @shadowkokufu9178 8 месяцев назад +1

    Really enjoying this - I'm using these videos to get that foundation and then going to my pharms notes and trying to predict the drug actions based off the receptor (need practice). Thanks!!
    Plus I'm watching this clip and my brain is filling in the blanks that you spoke of in other videos. The way that you do this makes stuff stick in my head. Thanks!!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  8 месяцев назад +1

      I am honored! I've covered more autonomic pharmacology in my pharmacology playlist;
      ruclips.net/p/PLYcLrRDaR8_d5RzuEJprW-NWXTK22ByVC&si=6_bmiW838rUPzL3y

    • @shadowkokufu9178
      @shadowkokufu9178 8 месяцев назад

      @MedicosisPerfectionalis Thanks!! I'm studying for my pharms test next week, so I'll definitely be going through there amongst other playlists. Thank you for the link!!

  • @mohdusman2436
    @mohdusman2436 2 года назад +3

    Man this stuff is going straight up in my brain in a easy way 🧠 thanks 🙏

  • @jmw77
    @jmw77 Год назад +3

    08:20 "why didn't we call it f protein as in F U" lmao I needed that

  • @WookieWoman
    @WookieWoman 3 года назад +8

    I learn so much from you that maybe I should start actually studying some form of medical science...

  • @jenniferhoule3233
    @jenniferhoule3233 2 года назад +2

    Wow! thank you so much! I finally understand What my professor was talking about!! Amazing explanation!!!!

  • @Muuip
    @Muuip Год назад +1

    Great concise presentation!
    Much appreciated!👍👍👍

  • @handsomejohnjohn
    @handsomejohnjohn Год назад +1

    Great video. A sense of humor helps. Thank you

  • @motivationpilldaily
    @motivationpilldaily 2 года назад +2

    Thank you for this awesome video.

  • @pinklavender1719
    @pinklavender1719 Год назад +2

    thank you for making it easier to understand!!!

  • @leagueofcow6403
    @leagueofcow6403 2 года назад +3

    Thank you so much!! truly amazing

  • @siddhantpandey4903
    @siddhantpandey4903 12 дней назад +1

    Helped me to clear veterinary pharmacology doubts

  • @alaamahmoud6625
    @alaamahmoud6625 3 года назад +2

    Amazzzzing simple and to the point thanks a lot

  • @kdee7891
    @kdee7891 Месяц назад +1

    I wish our professors would come to class and just tell us to watch these videos and close us for the day. Because this makes waaay more sense than sitting in a 3hr lecture

  • @tabassum3501
    @tabassum3501 3 года назад +3

    Loved the way u explained👍😊

  • @morganswanger6154
    @morganswanger6154 4 месяца назад +1

    Dude you're hilarious. I would watch this instead of a netflix show.

  • @arjunbaburaj3402
    @arjunbaburaj3402 Год назад +1

    Such a wonderful explanation...thank you so much @Genius

  • @husniyamuhalim5703
    @husniyamuhalim5703 3 года назад +3

    I am having a hard time understanding this topic but thanks you sir, I got a hang of it.

  • @collho
    @collho 3 года назад +5

    This is brilliant!! Thank you :)
    As a added benefit, you are also HILARIOUS :D

  • @Melissa-S
    @Melissa-S Год назад +1

    NO OTHER WORD TO DESCRIBE THIS THAN BRILLIANT!!!

  • @serotoninteam3866
    @serotoninteam3866 10 месяцев назад

    i cant thank you enough medicosis

  • @wongno8986
    @wongno8986 Год назад +1

    thank you so much it helps a lot!

  • @soulhunter4739
    @soulhunter4739 2 года назад +2

    thanks alot sir today is my pharmacology paper & it helped me alot🖤❤️

  • @farahmedhat2891
    @farahmedhat2891 2 года назад +2

    Great effort, thank you 😊 👏

  • @NERVESMEDICINE616
    @NERVESMEDICINE616 3 года назад +2

    Wow brother, its great to see your video
    Doing great work 👍

  • @tamanarawan8401
    @tamanarawan8401 11 месяцев назад +1

    Wow really appreciate your work .

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  11 месяцев назад +1

      I appreciate you too, Tamana!
      Would you please help me by sharing?

    • @tamanarawan8401
      @tamanarawan8401 11 месяцев назад +1

      @MedicosisPerfectionalis yes where should I share this?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  11 месяцев назад

      Please share my videos with friends on social media or by word of mouth!
      Thank you so much in advance!

  • @nikolakulik824
    @nikolakulik824 3 года назад +1

    Am I right that M3 receptors are stimulated in skeletal muscle vessels during exercise and cause vasodilation as a part of sympathetic response?

  • @thegreatpogi
    @thegreatpogi 3 года назад +9

    This guy making me laugh so hard and learning at the same time hahahaha! But fr though I got an upcoming board exam this march 10 and im weak at pharmacology but woah! The way you make fun of pharmacology is what makes me understand so much easier! Trust me ive learned a lot from you already thank you my man!!!!

    • @thegreatpogi
      @thegreatpogi 3 года назад +3

      Btw I subscribed hahahaha love from future philippine pharmacist here!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 года назад +1

      Wow 🤩
      Thank you so much 😊
      Good luck 🍀 to you!

    • @thegreatpogi
      @thegreatpogi 3 года назад +1

      @@MedicosisPerfectionalis you're very welcome! And all of your efforts are appreciated! Especially the "running from the tiger" shut them all dooooown!!! (Any shits that's not a necessity for running HAHAHAHAH) thank you rly thank you!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 года назад

      You’re very welcome 😊

  • @clarkkent4872
    @clarkkent4872 2 года назад +3

    Thank you so much. I wish I have found this channel earlier.

  • @karamabbas2922
    @karamabbas2922 3 года назад +2

    you are the god of teaching i hope if you were the president of education in the world

  • @zainabfarooq5263
    @zainabfarooq5263 Год назад +1

    Great work

  • @eddiedavisjr9771
    @eddiedavisjr9771 2 года назад +1

    This was wonderful.

  • @ruqaya7401
    @ruqaya7401 Год назад +2

    Great video thank you so much ❤️ 🔥

  • @user-dc8sk4em8b
    @user-dc8sk4em8b Месяц назад +1

    Excellent video to learn basics of psychopharmacology ( Not all intelligent people can teach - that requires talent too 👍 & you are awesome 👍 Keep going my friend).

  • @sukhveerkaur1390
    @sukhveerkaur1390 2 года назад +2

    Thanku so much 😀sooooo helpful , great work 👍

  • @matiullah757
    @matiullah757 Год назад +2

    What a lecture,u make my day😂🤓👏🏼✌

  • @jemjem1801
    @jemjem1801 3 года назад +2

    The best as usual ☺️

  • @zakirzak1494
    @zakirzak1494 3 года назад +2

    Supper stuff .... power packed 😉

  • @sarahhammo8496
    @sarahhammo8496 3 года назад +2

    beyond amazing!

  • @pavankalyan3360
    @pavankalyan3360 2 года назад +1

    Great work 🤗

  • @preethamyadav8907
    @preethamyadav8907 3 года назад +1

    Sir ,pls explain in detail case presentation of ENT,Ophthal,community practical exam cases.pls do reply.pls share it with us the case presentation.

  • @marianneke61
    @marianneke61 3 года назад +1

    Very helpfull thank you!!

  • @MyNameisDianaa
    @MyNameisDianaa 3 года назад +3

    Just in time for my Pharmacology birthday test!!

  • @klayman6670
    @klayman6670 Год назад +1

    Hello bro, I have a question where are nicotinic receptors most dense and where are muscaranic receptors most dense?

  • @IbiDon
    @IbiDon Год назад +2

    This guy is Pharmacologys kryptonite.

  • @user-kd1qm6qw7s
    @user-kd1qm6qw7s 2 года назад +2

    Thank you so much my Dr

  • @babyjanefabrigas6336
    @babyjanefabrigas6336 2 года назад +2

    Thank you!! 💜💜

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  8 месяцев назад +3

    🧠 Neuroanatomy Playlist: ruclips.net/p/PLYcLrRDaR8_cBHy0sWaCaLmOlJb9gzmA2&si=lnnSJhJJTUcfKl5b
    🥼 Clinical Neurology Playlist: ruclips.net/p/PLYcLrRDaR8_cQG-7JbGaeXsXGgBpK-Yzl&si=Qoi97evsN9uz-9Te
    💀 Anatomy Playlist: ruclips.net/p/PLYcLrRDaR8_cxbxAwLSQSx9v28Ezv3gQB&si=jqigBoyauPcen27C

  • @Sama-Rose
    @Sama-Rose 6 месяцев назад +1

    It is just amazing !! thank you
    how can we be like you one day ( a super doctor) ??!!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  6 месяцев назад

      Wow, thank you!
      Work hard every day for the next 10 years and you'll be way better than me!

  • @marryhawar4568
    @marryhawar4568 2 года назад +1

    Thank you so much! You explained in the best way .. but.. I think M2 receptor doesn’t cause decrease in heart contractility .. please tell me if I’m wrong

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  2 года назад +1

      You're right. M2 is present more in the atria than ventricles. So they work on decreasing heart rate, not necessarily contractility.

  • @gunjansharma9441
    @gunjansharma9441 3 года назад +1

    Why does Nicotinic cholinergic blocker causes paralytic asphyxia without heart failure?

  • @dissanayakesamantha805
    @dissanayakesamantha805 3 года назад +1

    awsome, thanks

  • @erraticansh8459
    @erraticansh8459 3 года назад +3

    You're underrated.

  • @user-ie7xg8qf7c
    @user-ie7xg8qf7c 8 месяцев назад

    Why is it that when someone is equally startled or nervous, they sometimes turn pale, while other times they blush? And why do people experience alternations of turning pale and blushing when they're embarrassed?

  • @sydney4492
    @sydney4492 2 года назад +1

    love your videos!

  • @konstantinsinichkin8855
    @konstantinsinichkin8855 4 месяца назад

    fly agaric helps to quit smoking?

  • @afzalpathan1156
    @afzalpathan1156 Год назад +1

    Wow too good 🤩🤩🤩

  • @franzsikaschulze8846
    @franzsikaschulze8846 Год назад

    boy, didnt find a video in my language about that topic and now I have to understand in English ._. still thankful XD

  • @mustafasafaa7215
    @mustafasafaa7215 3 года назад

    u ar great .. thanx pro

  • @shams8917
    @shams8917 7 месяцев назад +1

    Life saver ❤️‍🔥

  • @hemontikamukherjee9340
    @hemontikamukherjee9340 Год назад +1

    oh god, thank you so much!

  • @YoyoYoyo-lc6nb
    @YoyoYoyo-lc6nb 2 года назад +2

    Thanks❤

  • @lillaramonda
    @lillaramonda 2 года назад +3

    Hahahahahaha okay this guy is crazy 🤪 Thanks a looot 🤩
    And now baby I'm depolarized... 😍😎🤭

  • @nikolakulik824
    @nikolakulik824 3 года назад +1

    Are afferent nerve fibres divided into PANS and SANS or it it just efferent nerves?

  • @michaelsw0rd
    @michaelsw0rd 3 года назад +2

    HAHA 8:15 "Why is it not named F-protein, F as in F U" so relatable towards to material being studied

  • @MsPlus24
    @MsPlus24 3 года назад +3

    Ahhhh sooo beautifully explained!!!

  • @andre929
    @andre929 Год назад

    M2 - decease hr , decrease contractilty
    Inhibit parasymphatetic response ??

  • @omalsadahmad-yn9vu
    @omalsadahmad-yn9vu 14 дней назад +1

    Thanks

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  Год назад +2

    👨‍🏫 Physiology Playlist: ruclips.net/p/PLYcLrRDaR8_eAjmngd289ghWijs2wfqnj

  • @wardelias
    @wardelias Год назад

    if m3 is Gq coupled receptor and causes smooth muscle contraction, why does it cause relaxation of the GI sphincters instead of contraction? (though physiologically it makes sense, my question is mainly why its not through M2 or M4 but M3)

    • @shadowkokufu9178
      @shadowkokufu9178 8 месяцев назад

      Probably because it's not inhibitory? If it closed the sphincters then it would inbibit the GIT because there wouldn't be any movement of content.

  • @snoviasingh884
    @snoviasingh884 2 года назад +2

    I imagine the nicotinic receptor scream aggressively IM SICK AND TIRED OF BEING SICK AND TIRED XD

  • @thecharming473
    @thecharming473 2 года назад +1

    In M2 and M4 receptors shouldn't it be inhibition of sympathetic functions??

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  2 года назад +1

      Yes! I made a mistake!
      I should’ve wrote: “M2 and M4 stimulation is responsible for the inhibitory effects of parasympathetic.”

    • @thecharming473
      @thecharming473 2 года назад

      Yes...Thank you

  • @faithchisanga7117
    @faithchisanga7117 2 года назад +4

    I had fun😂🙏

  • @harshitamehra7827
    @harshitamehra7827 Год назад +1

    Thankyou

  • @janhavis.8360
    @janhavis.8360 3 года назад +1

    sir what coffee does to your heart rate? should i take coffee if i have a heart rate in a range of 50 to 55 ?

  • @simba_DIY
    @simba_DIY 4 месяца назад

    Thanks for the vedeo and congratulations for egypt the victory and quality for the second round in african cup . 🎉❤😂 If you watch footbal of course

  • @nitestriker9804
    @nitestriker9804 3 года назад +1

    are M1 receptors in the brain ??

  • @creationsworksa.k8042
    @creationsworksa.k8042 3 года назад +2

    Best best 💓

  • @mutsawashe3607
    @mutsawashe3607 3 года назад +1

    Beta 1 is the heart and beta 2 lungs
    Because we have 1 heart🫀 but 2 lungs🫁
    ☺️

  • @InertialFire312
    @InertialFire312 3 года назад +2

    Thanks for making a boring topic so entertaining :))

  • @EpitomeProductionz
    @EpitomeProductionz Год назад

    I have long covid nervous system dysfunction. Would you at all be willing to let me pay for your thoughts regarding this condition? There's mounting studies about Nicotine improving nervous system function and relieving symptoms, I am living proof. Unfortunately my damaged brain has a hard time understanding this video, but could I pay you to go over the topic with me as well as pick your brain on what you suggest? Doctors are at a loss of what to do, at least you have vast knowledge about these nervous systems and the cholinergic nervous system.

  • @meowmeowone8479
    @meowmeowone8479 3 года назад +5

    You forgot the most important receptor of them all, M sub P: Medicosis Perfectionalis! Hella funny awesomeness!

  • @toobaqureshi2980
    @toobaqureshi2980 3 года назад +2

    AWESOME