Nicotinic vs Muscarinic Receptors

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  • Опубликовано: 27 дек 2024

Комментарии • 255

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  4 года назад +19

    💊 Autonomic Pharmacology: www.medicosisperfectionalis.com/

  • @richardgriggs8525
    @richardgriggs8525 2 года назад +87

    I'm legit 60 seconds in and already this makes sense. My med school professors are world leaders on the ANS but can't be bothered to state the most foundational things in a straightforward way.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  2 года назад +3

      Thank you so much 😊 for watching!

    • @robertbruhcuh3634
      @robertbruhcuh3634 Год назад

      they don’t know lmao it’s most people especially teachers not college some college im pretty sure actually learn what they teach

  • @cardamomes
    @cardamomes 2 года назад +30

    Absolute perfection. Suddenly years of lectures makes sense in one video.

  • @grayhero1
    @grayhero1 3 года назад +26

    I'm preparing myself for my Pharmacology exam,and I watch your videos to give every topic a beautiful start,i know no means to say how useful these videos are.thank you MP.

  • @jacobbryan4875
    @jacobbryan4875 3 года назад +56

    One of the best explanations out there on this topic! Thanks a lot.

  • @danicahashimoto9833
    @danicahashimoto9833 11 месяцев назад +4

    I never comment on videos but I have to say this is one of the most helpful videos!! Taking my boards for becoming a Physician Assistant (PA) and these concepts always went over my head. So important to nail it down for all the pharmacology and functions. Thank you for this!!

  • @jonquilsimms97
    @jonquilsimms97 4 месяца назад +3

    Im a P1 student in Principles of Pharmacology and this definitely helped me to wrap my mind around what the receptors do omg. Thanks so much!

  • @sobster123
    @sobster123 2 года назад +13

    I've *always* struggled with pharmacology. Especially this topic. But my God. The way this GENIUS explained this. ❤️I could give him my soul. The best teacher ever. Thank you *so* much Mr Perfectionist.💞

  • @jennaalqdah9538
    @jennaalqdah9538 Месяц назад

    You're always gonna be the best teacher for med stuff. Thank you for helping me get through this.

  • @afifahbasirun3586
    @afifahbasirun3586 3 года назад +28

    Thank you so much.
    This is very helpful, it feels like you're slapping my brain with knowledge from my lectures but with more sense!!

  • @kdee7891
    @kdee7891 8 месяцев назад +4

    I wish our professors would come to class and just tell us to watch these videos and close us for the day. Because this makes waaay more sense than sitting in a 3hr lecture

  • @sherihanalmohammad7195
    @sherihanalmohammad7195 2 года назад +2

    this is by far the mosssssssssssssst useful piece of info I've found on RUclips or any other platform, with the best way to put it out
    wow, I still can't believe I've found you!
    Thankssssssssssssssssss

  • @ShinigamisBlade
    @ShinigamisBlade 10 месяцев назад +13

    Prepping for a test and the jokes are keeping me alive 😂

  • @KyleRayner12
    @KyleRayner12 4 года назад +9

    Thanks for explaining. You covered this better in 0.25 hr than my professor did in 1.5.

  • @هلالالحميري-د5ض
    @هلالالحميري-د5ض 4 года назад +34

    We are relly grateful for u sir,plz keep going ,I like the way that u explain, u make every thing easy ...thank u so much

  • @oliviam1999
    @oliviam1999 4 года назад +7

    thank you so much for explaining clearly, i love being explained to like i know nothing because i really know nothing

  • @rashialimbona1078
    @rashialimbona1078 2 года назад +3

    This is the first time I've watched your videos and I love it already. New subscriber gained!

  • @depharmily2064
    @depharmily2064 4 года назад +8

    THAT WAS FUNNY AND INFORMATIVE , THANK YOU SO MUCH, MUCH LOVE FROM SOUTH AFRICA

  • @jenniferhoule3233
    @jenniferhoule3233 2 года назад +3

    Wow! thank you so much! I finally understand What my professor was talking about!! Amazing explanation!!!!

  • @siddhantpandey4903
    @siddhantpandey4903 7 месяцев назад +2

    Helped me to clear veterinary pharmacology doubts

  • @Melissa-S
    @Melissa-S Год назад +1

    NO OTHER WORD TO DESCRIBE THIS THAN BRILLIANT!!!

  • @pinklavender1719
    @pinklavender1719 Год назад +2

    thank you for making it easier to understand!!!

  • @handsomejohnjohn
    @handsomejohnjohn 2 года назад +1

    Great video. A sense of humor helps. Thank you

  • @leobesa2887
    @leobesa2887 4 года назад +50

    Don't watch this at 1.5x speed

    • @Amerah-hs6ks
      @Amerah-hs6ks 8 месяцев назад +5

      This is literally what I intended to do🤣🤣💔

    • @choco_n0183
      @choco_n0183 2 месяца назад

      @@Amerah-hs6ks+

  • @romuellebarbado2088
    @romuellebarbado2088 3 года назад +5

    watching this before I take my quiz and it really is a huge help. Thank you sir

  • @WookieWoman
    @WookieWoman 4 года назад +9

    I learn so much from you that maybe I should start actually studying some form of medical science...

  • @mohdusman2436
    @mohdusman2436 3 года назад +4

    Man this stuff is going straight up in my brain in a easy way 🧠 thanks 🙏

  • @alexsheremett3097
    @alexsheremett3097 6 месяцев назад +1

    Get tired to be amazed. ... Thanks for the lesson❤

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  Год назад +3

    🧠 Neuroanatomy Playlist: ruclips.net/p/PLYcLrRDaR8_cBHy0sWaCaLmOlJb9gzmA2&si=lnnSJhJJTUcfKl5b
    🥼 Clinical Neurology Playlist: ruclips.net/p/PLYcLrRDaR8_cQG-7JbGaeXsXGgBpK-Yzl&si=Qoi97evsN9uz-9Te
    💀 Anatomy Playlist: ruclips.net/p/PLYcLrRDaR8_cxbxAwLSQSx9v28Ezv3gQB&si=jqigBoyauPcen27C

  • @shadowkokufu9178
    @shadowkokufu9178 Год назад +1

    Really enjoying this - I'm using these videos to get that foundation and then going to my pharms notes and trying to predict the drug actions based off the receptor (need practice). Thanks!!
    Plus I'm watching this clip and my brain is filling in the blanks that you spoke of in other videos. The way that you do this makes stuff stick in my head. Thanks!!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  Год назад +1

      I am honored! I've covered more autonomic pharmacology in my pharmacology playlist;
      ruclips.net/p/PLYcLrRDaR8_d5RzuEJprW-NWXTK22ByVC&si=6_bmiW838rUPzL3y

    • @shadowkokufu9178
      @shadowkokufu9178 Год назад

      @MedicosisPerfectionalis Thanks!! I'm studying for my pharms test next week, so I'll definitely be going through there amongst other playlists. Thank you for the link!!

  • @Shambhaviak
    @Shambhaviak 4 года назад +6

    Thank you so much!
    This was such a comprehensive and informative video
    I learnt the topic well :)

  • @karamabbas2922
    @karamabbas2922 4 года назад +2

    you are the god of teaching i hope if you were the president of education in the world

  • @morganswanger6154
    @morganswanger6154 11 месяцев назад +2

    Dude you're hilarious. I would watch this instead of a netflix show.

  • @harineepriya
    @harineepriya 2 года назад +2

    Thank you for this awesome video.

  • @husniyamuhalim5703
    @husniyamuhalim5703 3 года назад +4

    I am having a hard time understanding this topic but thanks you sir, I got a hang of it.

  • @clarkkent4872
    @clarkkent4872 3 года назад +3

    Thank you so much. I wish I have found this channel earlier.

  • @laibakhan4186
    @laibakhan4186 3 месяца назад

    it says that M2,M4 work through Gi which inhibits parasympathetic(6:47), but moving forward you mentioned that it decreases contractility of heart etc. could someone please explain what this means

  • @UmmerFaseel
    @UmmerFaseel 8 месяцев назад +1

    Excellent video to learn basics of psychopharmacology ( Not all intelligent people can teach - that requires talent too 👍 & you are awesome 👍 Keep going my friend).

  • @matiullah757
    @matiullah757 2 года назад +2

    What a lecture,u make my day😂🤓👏🏼✌

  • @tabassum3501
    @tabassum3501 3 года назад +3

    Loved the way u explained👍😊

  • @alaamahmoud6625
    @alaamahmoud6625 3 года назад +2

    Amazzzzing simple and to the point thanks a lot

  • @Muuip
    @Muuip 2 года назад +1

    Great concise presentation!
    Much appreciated!👍👍👍

  • @lillaramonda
    @lillaramonda 2 года назад +3

    Hahahahahaha okay this guy is crazy 🤪 Thanks a looot 🤩
    And now baby I'm depolarized... 😍😎🤭

  • @serotoninteam3866
    @serotoninteam3866 Год назад

    i cant thank you enough medicosis

  • @thegreatpogi
    @thegreatpogi 3 года назад +10

    This guy making me laugh so hard and learning at the same time hahahaha! But fr though I got an upcoming board exam this march 10 and im weak at pharmacology but woah! The way you make fun of pharmacology is what makes me understand so much easier! Trust me ive learned a lot from you already thank you my man!!!!

    • @thegreatpogi
      @thegreatpogi 3 года назад +3

      Btw I subscribed hahahaha love from future philippine pharmacist here!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 года назад +1

      Wow 🤩
      Thank you so much 😊
      Good luck 🍀 to you!

    • @thegreatpogi
      @thegreatpogi 3 года назад +1

      @@MedicosisPerfectionalis you're very welcome! And all of your efforts are appreciated! Especially the "running from the tiger" shut them all dooooown!!! (Any shits that's not a necessity for running HAHAHAHAH) thank you rly thank you!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 года назад

      You’re very welcome 😊

  • @Muhsina02
    @Muhsina02 8 дней назад

    Thank you so much.... That was really helpful ❤

  • @nikolakulik824
    @nikolakulik824 3 года назад +1

    Am I right that M3 receptors are stimulated in skeletal muscle vessels during exercise and cause vasodilation as a part of sympathetic response?

  • @ruqaya7401
    @ruqaya7401 2 года назад +2

    Great video thank you so much ❤️ 🔥

  • @soulhunter4739
    @soulhunter4739 3 года назад +2

    thanks alot sir today is my pharmacology paper & it helped me alot🖤❤️

  • @sukhveerkaur1390
    @sukhveerkaur1390 3 года назад +2

    Thanku so much 😀sooooo helpful , great work 👍

  • @collho
    @collho 3 года назад +5

    This is brilliant!! Thank you :)
    As a added benefit, you are also HILARIOUS :D

  • @arjunbaburaj3402
    @arjunbaburaj3402 2 года назад +1

    Such a wonderful explanation...thank you so much @Genius

  • @jemjem1801
    @jemjem1801 3 года назад +2

    The best as usual ☺️

  • @Sama-Rose
    @Sama-Rose Год назад +1

    It is just amazing !! thank you
    how can we be like you one day ( a super doctor) ??!!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  Год назад

      Wow, thank you!
      Work hard every day for the next 10 years and you'll be way better than me!

  • @MyNameisDianaa
    @MyNameisDianaa 4 года назад +3

    Just in time for my Pharmacology birthday test!!

  • @leagueofcow6403
    @leagueofcow6403 3 года назад +3

    Thank you so much!! truly amazing

  • @farahmedhat2891
    @farahmedhat2891 3 года назад +2

    Great effort, thank you 😊 👏

  • @klayman6670
    @klayman6670 2 года назад +1

    Hello bro, I have a question where are nicotinic receptors most dense and where are muscaranic receptors most dense?

  • @Kynxs
    @Kynxs 2 месяца назад

    I’m watching the M1 B1 M2 AND THIS MAN IS COOKING WOTH THE ANALOGIES

  • @eddiedavisjr9771
    @eddiedavisjr9771 2 года назад +1

    This was wonderful.

  • @wongno8986
    @wongno8986 Год назад +1

    thank you so much it helps a lot!

  • @babyjanefabrigas6336
    @babyjanefabrigas6336 2 года назад +2

    Thank you!! 💜💜

  • @gunjansharma9441
    @gunjansharma9441 3 года назад +1

    Why does Nicotinic cholinergic blocker causes paralytic asphyxia without heart failure?

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  Год назад +2

    👨‍🏫 Physiology Playlist: ruclips.net/p/PLYcLrRDaR8_eAjmngd289ghWijs2wfqnj

  • @NERVESMEDICINE616
    @NERVESMEDICINE616 4 года назад +2

    Wow brother, its great to see your video
    Doing great work 👍

  • @IbiDon
    @IbiDon Год назад +2

    This guy is Pharmacologys kryptonite.

  • @zainabfarooq5263
    @zainabfarooq5263 2 года назад +1

    Great work

  • @thecharming473
    @thecharming473 2 года назад +1

    In M2 and M4 receptors shouldn't it be inhibition of sympathetic functions??

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  2 года назад +1

      Yes! I made a mistake!
      I should’ve wrote: “M2 and M4 stimulation is responsible for the inhibitory effects of parasympathetic.”

    • @thecharming473
      @thecharming473 2 года назад

      Yes...Thank you

  • @erraticansh8459
    @erraticansh8459 4 года назад +3

    You're underrated.

  • @عمرالطائي-ح7ب
    @عمرالطائي-ح7ب 3 года назад +2

    Thank you so much my Dr

  • @pavankalyan3360
    @pavankalyan3360 3 года назад +1

    Great work 🤗

  • @jmw77
    @jmw77 Год назад +3

    08:20 "why didn't we call it f protein as in F U" lmao I needed that

  • @marryhawar4568
    @marryhawar4568 2 года назад +1

    Thank you so much! You explained in the best way .. but.. I think M2 receptor doesn’t cause decrease in heart contractility .. please tell me if I’m wrong

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  2 года назад +1

      You're right. M2 is present more in the atria than ventricles. So they work on decreasing heart rate, not necessarily contractility.

  • @afzalpathan1156
    @afzalpathan1156 Год назад +1

    Wow too good 🤩🤩🤩

  • @franzsikaschulze8846
    @franzsikaschulze8846 Год назад

    boy, didnt find a video in my language about that topic and now I have to understand in English ._. still thankful XD

  • @Yan-e5u
    @Yan-e5u Год назад

    Why is it that when someone is equally startled or nervous, they sometimes turn pale, while other times they blush? And why do people experience alternations of turning pale and blushing when they're embarrassed?

  • @nikolakulik824
    @nikolakulik824 3 года назад +1

    Are afferent nerve fibres divided into PANS and SANS or it it just efferent nerves?

  • @zakirzak1494
    @zakirzak1494 4 года назад +2

    Supper stuff .... power packed 😉

  • @wardelias
    @wardelias 2 года назад

    if m3 is Gq coupled receptor and causes smooth muscle contraction, why does it cause relaxation of the GI sphincters instead of contraction? (though physiologically it makes sense, my question is mainly why its not through M2 or M4 but M3)

    • @shadowkokufu9178
      @shadowkokufu9178 Год назад

      Probably because it's not inhibitory? If it closed the sphincters then it would inbibit the GIT because there wouldn't be any movement of content.

  • @shams8917
    @shams8917 Год назад +1

    Life saver ❤️‍🔥

  • @konstantinsinichkin8855
    @konstantinsinichkin8855 11 месяцев назад

    fly agaric helps to quit smoking?

  • @sarahhammo8496
    @sarahhammo8496 4 года назад +2

    beyond amazing!

  • @YoyoYoyo-lc6nb
    @YoyoYoyo-lc6nb 2 года назад +2

    Thanks❤

  • @andre929
    @andre929 Год назад

    M2 - decease hr , decrease contractilty
    Inhibit parasymphatetic response ??

  • @MsPlus24
    @MsPlus24 3 года назад +3

    Ahhhh sooo beautifully explained!!!

  • @bristol1946
    @bristol1946 6 месяцев назад +1

    Amazing. 😄

  • @marianneke61
    @marianneke61 3 года назад +1

    Very helpfull thank you!!

  • @ThatsWhy-
    @ThatsWhy- 3 года назад +1

    How does M4 receptor function ?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 года назад

      Gi-coupled receptor.

    • @ThatsWhy-
      @ThatsWhy- 3 года назад

      @@MedicosisPerfectionalis m2 for heart receptor, but what about M4 receptor for and its function?

  • @preethamyadav8907
    @preethamyadav8907 4 года назад +1

    Sir ,pls explain in detail case presentation of ENT,Ophthal,community practical exam cases.pls do reply.pls share it with us the case presentation.

  • @alphagonist4748
    @alphagonist4748 4 года назад +1

    Actions of adrenergic and anticholinergic agonists same?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 года назад

      What do you mean by “anticholinergic agonist”?

    • @alphagonist4748
      @alphagonist4748 4 года назад

      @@MedicosisPerfectionalis sorry lol
      It's adrenergic agonist vs cholinergic antagonist
      Do they have same action?

  • @faithchisanga7117
    @faithchisanga7117 2 года назад +4

    I had fun😂🙏

  • @chemdissa
    @chemdissa 3 года назад +1

    awsome, thanks

  • @snoviasingh884
    @snoviasingh884 3 года назад +4

    I imagine the nicotinic receptor scream aggressively IM SICK AND TIRED OF BEING SICK AND TIRED XD

  • @michaelsw0rd
    @michaelsw0rd 3 года назад +2

    HAHA 8:15 "Why is it not named F-protein, F as in F U" so relatable towards to material being studied

  • @hemontikamukherjee9340
    @hemontikamukherjee9340 Год назад +1

    oh god, thank you so much!

  • @nitestriker9804
    @nitestriker9804 3 года назад +1

    are M1 receptors in the brain ??

  • @janhavis.8360
    @janhavis.8360 4 года назад +1

    sir what coffee does to your heart rate? should i take coffee if i have a heart rate in a range of 50 to 55 ?

  • @EpitomeProductionz
    @EpitomeProductionz Год назад

    I have long covid nervous system dysfunction. Would you at all be willing to let me pay for your thoughts regarding this condition? There's mounting studies about Nicotine improving nervous system function and relieving symptoms, I am living proof. Unfortunately my damaged brain has a hard time understanding this video, but could I pay you to go over the topic with me as well as pick your brain on what you suggest? Doctors are at a loss of what to do, at least you have vast knowledge about these nervous systems and the cholinergic nervous system.

  • @sydney4492
    @sydney4492 3 года назад +1

    love your videos!

  • @creationsworksa.k8042
    @creationsworksa.k8042 3 года назад +2

    Best best 💓