mtor signaling pathway

mtor signaling pathway - This lecture explains about the mTOR pathway which is a part of survival pathway of cell signaling that helps in cell growth and proliferation.
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Thank you for watching

[@ahmadfraz3059]

Excellent! Made it so clear and easy to understand

[@shomusbiologyofficial]

Thank you

[@AmitKumar-em3vz]

What to say Dada.... You made it so simple. Thank you.

[@shomusbiologyofficial]

You're welcome

[@somasish]

When did S6K become a transcription factor? Could you kindly direct me to the publications!!Thanks

[@Padmashrinaren]

So simple yet significant
Thanks 🙏🙇

[@shomusbiologyofficial]

You're welcome

[@EricSartori]

Great video sir! Thank you for bringing this information to RUclips. 👍

[@shomusbiologyofficial]

Glad it helped

[@abishek8083]

Sir can you post questions from mTor, map-kinase , wnt , etc related to RTKs. Please reply me

[@iiiarmchair]

Nice video except it's WRONG!
Your diagram is right, but where it says protein synthesis is upregulated, you describe mTORC1 as upregulating TRANSCRIPTION.
s6K is not a transcription factor, it's a kinase, which goes on to phosphorylate ribosomal protein s6 to facilitate protein TRANSLATION. mTORC1 also upregulate the phosphorylation of 4EBP1 (eIF4E-binding protein 1) which makes it come off eIF4E allowing eIF4E to be free to bind other TRANSLATION initiation factors such as eIF4G.
Best wishes, @DrSimonCooper

[@heena3546]

Simon Cooper sir may i know your e mail?

[@fast6232]

Check out the big brain on Simon

[@DeliciaTrini]

Excellent! Thanks!🙌🏾

[@shomusbiologyofficial]

You're welcome

[@amirulfaez8437]

YOU SIR.....ARE THE BEST!!!

[@shomusbiologyofficial]

+Amirul Faez thank you

[@user-jo8zk4kj4u]

nice ppt :) however s6k and 4ebp are translation factors -not transcription factors

[@rojintj1]

Thanks man... this was super helpful!

[@chicong87]

Thanks for your videos, but, your englist acent is a bit little difficult to understand. I hope you can make english subtitle for your videos. It's really help

[@hkgs_knight4216]

You are amazing

[@ned9819]

Dude your amazing you should sit the USMLE bro

[@kristalografas6955]

Nice, S6K is now a transcription factor, grab the Nobel, congs!

[@syahirahdalawi3859]

thanks a lot!

[@adnanreddy1616]

Ummm... How do you cite youtube videos?

[@edandrew5547]

Thank you!!

[@VickyJennings19]

Can you provided where you got the figures from?

[@ronytesler]

What is the source of the first diagram (mTOR pathway)?

[@harishbharambe7880]

4EBP1 is not a Transcription Factor, rather it is a part of the translation machinery where it functions as a Kinase to promote translation.........Please edit or remake the video...........

[@abdikadirhassanabdullahi1535]

Thanks you shomus biology how caN I reach you in person

[@jayem5738]

thank you

[@somasish]

4E-BP1 is also not a transcription factor!!! Could you direct me to your source of information about S6K and 4E-BP1. Thanks

[@iiiarmchair]

Agreed. This video is wrong with respect to p70S6k (s6k) and eIF4E-BP1 (4E-BP1).

[@TheBeAuTiFuLsOuL85]

then what are those?

[@iiiarmchair]

TheBeAuTiFuLsOuL85 They are not transcription factors, they are involved in facilitating (or hindering in the case of4E- BP1), TRANSLATION of mRNA.

[@chankitgoswami3969]

S6kinase and eif-4e are the proteins which involve in protein synthesis.. In respect to mtor pathway.

[@neal84243]

Europe is not a continent

[@johnmandrake8829]

this was great, I would have subscribed and liked if I hadn't already :)

[@shomusbiologyofficial]

+John Mandrake keep sharing.

[@DanlekVideos]

Men ignore all this shit coments, I want to thank you, I am from Brazil and we don't have almost anything in our language to learn that! thank you!

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Thank you so much for appreciating my efforts

[@AmitKumar-em3vz]

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You can meet me when you visit Kolkata

[@AmitKumar-em3vz]

One day I will sure visit you Sir. With Best Regards.

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[@shomusbiologyofficial]

Why sick. You should be thanking me then