mtor signaling pathway
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- Опубликовано: 6 сен 2024
- mtor signaling pathway - This lecture explains about the mTOR pathway which is a part of survival pathway of cell signaling that helps in cell growth and proliferation.
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Thank you for watching
Excellent! Made it so clear and easy to understand
Thank you
What to say Dada.... You made it so simple. Thank you.
You're welcome
When did S6K become a transcription factor? Could you kindly direct me to the publications!!Thanks
So simple yet significant
Thanks 🙏🙇
You're welcome
Great video sir! Thank you for bringing this information to RUclips. 👍
Glad it helped
Sir can you post questions from mTor, map-kinase , wnt , etc related to RTKs. Please reply me
Nice video except it's WRONG!
Your diagram is right, but where it says protein synthesis is upregulated, you describe mTORC1 as upregulating TRANSCRIPTION.
s6K is not a transcription factor, it's a kinase, which goes on to phosphorylate ribosomal protein s6 to facilitate protein TRANSLATION. mTORC1 also upregulate the phosphorylation of 4EBP1 (eIF4E-binding protein 1) which makes it come off eIF4E allowing eIF4E to be free to bind other TRANSLATION initiation factors such as eIF4G.
Best wishes, @DrSimonCooper
Simon Cooper sir may i know your e mail?
Check out the big brain on Simon
Excellent! Thanks!🙌🏾
You're welcome
YOU SIR.....ARE THE BEST!!!
+Amirul Faez thank you
nice ppt :) however s6k and 4ebp are translation factors -not transcription factors
Thanks man... this was super helpful!
Thanks for your videos, but, your englist acent is a bit little difficult to understand. I hope you can make english subtitle for your videos. It's really help
You are amazing
Dude your amazing you should sit the USMLE bro
Nice, S6K is now a transcription factor, grab the Nobel, congs!
thanks a lot!
Ummm... How do you cite youtube videos?
Thank you!!
Can you provided where you got the figures from?
What is the source of the first diagram (mTOR pathway)?
4EBP1 is not a Transcription Factor, rather it is a part of the translation machinery where it functions as a Kinase to promote translation.........Please edit or remake the video...........
Thanks you shomus biology how caN I reach you in person
thank you
4E-BP1 is also not a transcription factor!!! Could you direct me to your source of information about S6K and 4E-BP1. Thanks
Agreed. This video is wrong with respect to p70S6k (s6k) and eIF4E-BP1 (4E-BP1).
then what are those?
TheBeAuTiFuLsOuL85 They are not transcription factors, they are involved in facilitating (or hindering in the case of4E- BP1), TRANSLATION of mRNA.
S6kinase and eif-4e are the proteins which involve in protein synthesis.. In respect to mtor pathway.
Europe is not a continent
this was great, I would have subscribed and liked if I hadn't already :)
+John Mandrake keep sharing.
Men ignore all this shit coments, I want to thank you, I am from Brazil and we don't have almost anything in our language to learn that! thank you!
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One day I will sure visit you Sir. With Best Regards.
Sick of this guy he's everywhere in biology lecture
Why sick. You should be thanking me then