The tendency for vomiting from thebaine and other non psychoactive alkaloids in opium makes it ,opium,quite difficult to overdose from. If a user has no tolerance, they’ll likely vomit before it’s all absorbed. If a tolerance is present in a user, that in itself would also be a hinderance to overdose on top of the thebaine. Laudanum is problematic because it has large amounts of opium dissolved into a liquid and therefore a very large amount of morphine and codeine. Much more than just opium dissolved into a tea. It’s really beyond me why opium is illegal. If it were legally available, just by growing one’s own supply,fentanyl and heroin market would be reduced drastically. Humans have been using opium for at least 10k years. It was never much of a problem until modern drug laws were passed. Immediately, the most concentrated and potent and therefore addictive and deadly versions of the drug(opioids)were being smuggled and sold on the black market for astronomical profit margins. It’s not a mysterious phenomenon.
I would love to agree and on paper some of what you said makes sense but from over a decade of personal experience with different forms of opium from smoking and orally ingesting refined opium to drinking my fair share of unrefined poppy pod and seed brews what youve said is just not the case at all (do not underestimate the potency of poppy tea, its often more intense than smoking the refined product and a single dose lasts upto 24 hours with a peak that lasts about 6-7 hours). The nature of Opiate addiction leads addicts to push things as far as possible everyday, once youve experienced nodding out on huge doses its the only way you can feel satisfied, anything less than nodding out for hours on end everyday no longer satisfies leading the addict to skirt the edge of overdose on a daily basis in order to achieve a nod, as they do this they also compensate for the ever growing tolerance with larger doses. Poppy tea is especially dangerous for overdose due to not just the drastic variation in potency from batch to batch but also due to its incredibly long half life leading to a buildup in your system if you redose within 24 hours of you original dose, I have experienced more than one overdose from Poppy tea due to these reasons and my tolerance was incredibly high from Oxycodone use back then. The other issue with poppy tea overdose is the fact that the peak of effects lasts for upto 7 hours and Nalaxone only works for about an hour meaning you constantly need to re-administer naloxone for many hours until the peak ends and breathing starts to return to normal, this means the user will be in precipitated withdrawal for upto 8-10 hours which is dangerous in and of itself. Another point Id like to make is the fact that tolerance to the different effects of Opioids rises at significantly different rates, tolerance to the nausea increases faster than any other effect whereas tolerance to the respiratory depression increases slower than any other effect including analgesia and subjective euphoria which also counters your point. Id also like that add that Ive actually overdosed on Thebaine due to the recall of toxic poppy seeds that were circulated in stores around Australia in 2022 and mistakenly sold as papaver somniferum. While the Thebaine caused major convulsions and muscle spasms along with tachycardia and high blood pressure among other negative effects I didn’t have a single hint of nausea and didn’t throw up at all. This is actually the event that got me to finally quit opioids as poppy seeds and pods are the only source of opioids I have available to me at this point in my life and I dont want to risk another toxic batch.
I used to drink poppy tea quite a bit. I got a batch of seeds once ( Seed tea, this was the last time I used it ) that had what I suspected of high amounts of thebaine. It was giving me LOTS of anxiety and seizure like jerks when I would try to sleep . Like little mini seizures, was this from thebaine? It was *really* scary
@@mvmusic8467 Don’t drink as much poppy tea. Yes it DEFINITELY is stronger than smoking it. At some point you have to use judgement. There’s a ceiling effect as you only have so many opioid receptors. Some people will push themselves beyond reasonable doses on anything. Take alcohol for example. My point is, making it illegal has just made opiates more and more dangerous. It’s going to be much more difficult to push your luck with opium than it is with fentanyl. You used oxycodone. That’s where your tolerance came from. If you grew up in a culture where opium was more understood and available legally, you likely wouldn’t have learned to do as much as humanly possible every time you were lucky enough to get it in your hands. As far as the half life goes, it lasts the same as morphine because that’s what it is. It’s just not refined down to its active ingredient which provides a buffer. I’m sorry you had to experience thebaine that way. Definitely be sure about what you’re taking. It’s still much easier to determine proper poppy plants than it is to guess what’s in the white powder or black tar that is currently easily available in every community. If you do use opiates or any drug again, always remember that they are much more effective and safe if used in moderation. That includes alcohol and cannabis.
@@Aspiring-Hobo Idk it could have been. It also could’ve been contaminated with any number of toxic substances or bacteria.Be sure you know what you’re ingesting. Tea made from seeds isn’t likely to be very good even if it were a safe batch. Use dried pods from garden poppies. You can grow them in most places as long as you don’t plant a field and start producing narcotics. It’s the last part that gets you in trouble so be careful.
You sound like you're in active addiction. Habitually taking opium and it's derivatives is certainly not benign. Just because something is natural doesn't mean it's better for you
one of those videos and channels where its like old RUclips. It hasn't blown up, no bots, no politics, and no bizarre arguments. Just people interested in the topic and discussing it. Nice.
@@Bozemanjustin Ice cream can be tainted with bones because of marshmallows so ice cream free of bones depends upon added ingredients. Only home made can be determined to be made from marsh mallow plant instead of animal byproducts.
@@Chillinn33Yes true.They can b lil.Annoying if read .Opium Tincture.was As good as Garlic./Monoclonal.Antibodies.all in 1.but no more sick.of it Lit..
Clicking on this video, I was hoping for a simple recipe. Something like "Add 100g of sugar to 1l of water, bring it to a boil, add a pinch of salt, stir 3 times to the left, 7 times to the right, say a magic spell and poof you got a pot full of Vicodin." Still very interesting though.
Vicodin? Mostly asprin in that crap. Im crossing my fingers for the end of the failed "war on drugs" imagine just brewing your own dope. I'm hoping for a very different looking future
@@lefthookouchmcarm4520I mean the thumbnail text says “opiates brewed from sugar” making it sound pretty simple, like brewing a cup of tea. But if it was that easy sugar would be illegal
@@Machinesofdrunkenhate well, it's technically, specifically, acetaminophen rather than aspirin - Vicodin is by definition hydrocodone and APAP, though there are other preparations containing NSAIDs like Ibuprofen and maybe Aspirin, but I'm guessing they're sold under a different trade name. Also you can remove the Tylenol and isolate the hydrocodone in like 20 minutes. Hydrocodone on its own is perfectly fine, its strength is either on par with or slightly below that of morphine on a mg per mg basis, I don't recall off the top of my head, but nothing really to turn your nose up at.
I used to live where they grew opium poppies on farms to harvest the seeds. These were for bakers to put on hard rolls and bagels etc. You know, those tiny black seeds. Birds spread them all over the area. There were poppies growing through the cracks in the sidewalk, along the train and trolley car tracks, just about every open space where weeds were growing. I don’t know what type of poppies they were but they looked exactly like the photos on this video. I would go first thing in the morning for a walk and slice the pods along my route. I had learned when and how to do it. In early afternoon I would retrace my steps and by then the white latex had turned black. I would harvest it, roll it into a little ball, which grew bigger day by day during the season. I would pinch off a tiny bit, and either dissolve it in a cup of tea or just swallow it. I got stoned as hell! Lasted all day. 😁 this was in Europe. Where I’m not going to say. The poppy seed industry no longer exists thanks to the do gooders, but our friends the birds have spread it all over the place.
Papaver somniferum is what is grown for bread seed and baked goods in Czech republic,Hngary and Poland and it contains both morphine and codeine, it's not very different from afghani or turkish poppies really. They can be and are used to make opium and other drugs. There was a fad of buying blue poppy seed in bulk from groccery strores and washing the seeds with water to recover the small amount of latex leftover on the seed from mechanical harvesting. it worked to one degree or another with pretty much any store bought poppy seed but was dangerous due to never knowing the concentration of the solution and people overdosed a few times and thank you for pointing out that poppies don't need "good farmland" as claimed by the video and will grow in various soils anywhere it can get a foot hold and a little water occasionally. othere than they absolutely hate to be transplanted or have their roots otherwise disturbed poppies are failry easy to grow as an annual in almost all of north america,europe,the middle east,africa and asia. There are also signifigant poppy farms in Tasmania south of Australia. the video also fails to mention that cannabis is a major crop in afghanistan that requires irrigated good land or fertilizer to produce well whereas poppies and wheat require less water so they are really competing for second place not first
I had a friend, years ago that would make poppy tea from dried bulbs. I don't know the recipe, but it was a nice calming sensation, no euphoria, etc, just a calm, snoozy drink, and apparently legal to make at the time. I won't say it tasted great, or good, or even easy to drink, but she did manage to make it taste better, and less bitter over time, to the point where it resembled a natural tea, than a curious concoction of chemistry. I suppose it would be more or less like the best possible situation with Kratom, without "the urge to purge". I really miss those days :) Peaceful talks, and face to face relationships with no walls, or anxiety in the way. What a wonderful gift that few people realize plants, and flowers have given us. It's really sad that feeling well, and healthy is on the edge of illegal due to abuse of these gifts.
You tube and Google changed there arrymitic to show you lsearch results with more adds and barrie the your search stuff than they just read those searches over when you burn them out and never give you what you truly want.Nasty seeding triggering, redrecting,socal engineering attack since its attacking your searches aginst you.
As a molecular biologist, I can assure you there's no such thing as a dead end in this field. There are setbacks and delays, sure. Long stretches with no discernable progress being made. Months of head scratching and seemingly endless troubleshooting come with the territory. But the tools and techniques of the trade are vast, and the ways in which they can be modified or combined are limited only by one's ethics and imagination.
Yup they can copy paste the genes to all kinds of things. Yeastie beasties would be the best host for making narcotics like morphine etc. Fungi have more helper genes and hardware inside for chemical synthesis than bacteria. ❤
And exactly as stated why is it OK for a runner to run for the high but not for the opium smoker to smoke for the high? It's called broken reality. Rules for thee but not for me. An indulger of food gets diabetes and its poor harry. An indulger of heroin gets addicted and he is bad man.
A lot has happened in this field since those two papers. One of the authors of the original 2015 paper went on to found the biotech company Antheia, who recently partnered with API manufacturer Olon Group to produce thebaine on a commercial scale. We’re actually quite close to seeing this technology potentially replace opium poppies. Antheia also has some interesting patents regarding the improvements they’ve made to the process.
@@StarThistle-c7xyou’ve probably ate GMO food at some point during your week. just bcuz you don’t fully understand something, doesn’t make it inherently evil
Could be revolutionary... In a few days, a lab could make a ton of heroin! Way better than the fentanyl junk we get now. A flood of high grade morphine and heroin, with no poppy fields necessary, just sugar and bioengineering. Would make drug enforcement completely unenforceable.
You're kind of wrong about the definition of opioid. "Opioid" doesn't have anything to do with natural or synthetic: opioids are simply anything that interacts with the opioid receptors, and opiates come directly from opium poppies. All opiates are opioids, but not all opioids are opiates. Mitragynine and 7-hydroxymitragynine are both natural indole alkaloid opioids that are either consumed in or extracted from plant material, but they're not opiates.
The alkaloids in Mitragina speciosa dont't come from Papaver sp. Hence they're not opiates. He was not saying that they have to come from a plant to be opiates but they have to come from Papaver sp.
@@chrisbrent7487True, but that was mentioned, and you completely missed the point. The point was that the word "opioid" is used for any substance that interacts with the opioid receptors in the body.
@@huhdidwhat He wasn't suggesting that an opioid has to be synthetic or semi synthetic though, just that they are not a natural constituent of P. somniferum. The major alkaloids of M. speciosa are considered opioids and you are correct about that.
@@chrisbrent7487at least in the length of the video I’ve watched, he states “Opiate: extracted from opium, and Opioid: mimics natural substances from the opium plant (synthetic)”. While heroin is synthetic, it’s of opiate structure, whereas like the other commenter is saying, kratom is organic and an opioid. What I’ve been taught is Opiates are any drugs from the opium poppy as stated, but also certain synthetic drugs that follow the same pattern of structure, like heroin, oxycodone, hydromorphone, etc. Opioid, however, is any drug that interacts with opioid receptors in the expected way, like kratom (Mitragynine and others), fentanyl, nitazenes, etc. An exception that I know of is salvia divinorum, because while its main chemical salvinorin a is a kappa opioid receptor agonist, it isn’t referred to as an opioid due to its atypical dissociative effects and lack of expected anxiolysis and analgesia, tho I find it kinda numbing and therefore analgesic at times. A rule to rule to remember for anyone reading is all opiates are opioids, but not all opioids are opiates. Still confusing, but that helped me. Please correct me if I’m wrong about any of this, but this is what I’ve gathered over the years of casual research as I’ve always been more interested in chemicals that lead to a state of psychedelia or dissociation, but I think I’ve learned a decent amount
I'm currently hooked on kratom.. it got me off heroin and helped me stop drinking which I'm thankful for but I've been on 4-5tsp x3 a day for about 4 years..
A few years ago I learned that growing poppy in America is totally legal so long as you don't process it. I just got a few hundred seeds and am creating the compost for them this fall. I am also going to start growing Aztec tobacco next year.
Beautiful flowers on very showy stems, a self-sowing treat for a garden. Both bumble bees and honey bees go crazy for the pollen. I've seen half a dozen rolling around in a single flower, a sight and sound that does the heart good. In my rainy climate they stay upright when wet, unlike, say, irises which tend to fall over. You will easily collect a pint of tasty seeds (expensive to buy) from a few plants. I don't understand why our narrator says that the plant is good only for the opiates. I hope you get good germination and have them for years to come.
@@stephencuffel4932 Thank you very much for the encouragement. I'm looking forward to seeing how they do here in Florida. I know that poppys want that initial cold snap early on. So I'm thinking mid October or November to sow and they should germinate throughout the winter. I guess they're like strawberries when it comes to cold snaps. They love em if they don't get too cold for too long. The tobacco I do intend to harvest and smoke. I quit smoking cigarettes a few years ago and don't want to pick it back up but I want to use it how it was used back in the past. So small shallow bowl and like one hit from a peace pipe. The Aztec I grabbed is Nicotiana Rustica. Neither were that expensive either. I think the poppys were like 8$ for 100 seeds and that included shipping. The tobacco I think was about the same price as well for 100 seeds and shipping.
I stumbled randomly around this video, due to youtube algorithm. I worked professional as a nurse before switching to computer science and I was always interested in chemistry and biology. Even though I don’t understand the whole process due to lack of knowledge it's incredible to see what is possible. So I guess thank you for your video!
Just started watching but already saying, having an alternative source of opiates/oids might come in handy in a shtf situation where painkillers might become unavailable.
Here it is legal to grow opium poppies, it is just the use and extraction that is illegal. And it is same rules in most of the world. I have been thinking the same that it might be wise to have some opium plants just in case something happens and no painkillers is available anymore (either from war or more likely bureaucrats closing down on mediacal opiate use )..
@@stephenroldan5107mentioned this on my reply to a64738, that it's probably the only one that would grow in the tropics. Weird that my comment seem to just have disappeared.
Two years ago, my mother in law was prescribed opium as she was entering chemotherapy. She gave the bottle to me. At that time, I "had been around the block" regarding everything available on the street. It was a 25 year experience that had been ceased for ten years when she gave me the bottle. I took a 10ml dose from the bottle. My first dose felt "cleaner", if that makes any sense, and I had no stomach issues. It felt like a 10mg percocet, but "cleaner". The 150ml bottle lasted me a year. It was fantastic. No hangover, but I did recognize a tolerance by day three.
Hangover? Is that a subtle term for "potential relapse into full fledged use & dependence"? Opiates don't produce "hangovers" e.g. alcohol, or in any conventional sense. It's only a matter of time before dependence on both a biological & conscious level occurs; "recreational, frequent use of opiates responsibly forever" is a lie. An impossibility. The closest thing to a "hangover" is the painful reaction created by newly created µ & related receptors emptying & resulting in the mind reeling in agony & imbalance to some degree. Manifesting as mere irritability, discomfort/craving, all the way to utter dysfunction & excruciating withdrawal from the brain being perpetually chemically rewired. Each time anyone ingests an opiate agonist, a permanent change is created in the brain from which it never heals. There's no "reset" button, just dogma & wishful thinking. Opiate agonists, alcohol, benzodiazepines (created in large part as substitutes for what natural opiates were once used for, before Harry J Anslinger & his goons got the US & much of the world to outlaw them), barbiturates, alcohol... All have one thing in common: They create chemical changes in the brain on the level of DNA. Much in pop culture glorifies the use of alcohol & hard drugs, baiting & hooking more souls into a burgeoning black market in the US & increasingly the world over. The DEA (among others), in defiance of basic human rights & our constitution, work hand in hand with them, creating a devastating blight on society. DEA ensures the black market for "scheduled" or illegal, pernicious commodities thrives by adding a heavy element of risk targeting the upper-middle to lower part of said market, ensuring it's very existence & survival, along with it's perpetual bloodshed. The illicit market provides often lethal products leading to untold suffering & death to Americans who pay an egregiously inflated price for a usually potentially lethal, often extremely harmful, adulterated & unfit end product. This also helps keep the US's world record prison population growing & often over capacity. 20% of the world's prisoners are in the US, with only roughly 5% of the word's population. Statistics show the very existence of DEA & their futile, deadly war on drugs result in yet more consumers for the black market, simply by taking advantage of youthful rebellion & human nature: telling people they aren't allowed to ingest something only ensures many defy the unreasonable imposition & do the opposite. Sad but true.
This sounds good, OR, we could stop acting like tyrants, use the gifts nature has provided and stop making people in pain jump through hoops to get the relief they need.
Oh it's worse than that. I had a fight with my insurance company that lasted 4 years(thanks Obamacare) to get a fusion, by then end of the 4 years i was permanently disabled and had been on pain management a few years. Post 2 surgeries I took myseldnoffnof.pain management where my monthly bill was 250 a month and I never failed a urine test nor missed a pill in the monthly count. Then my primary care physician moved to be close to his kids in college. I then spent 3 years searching for a family or primary care doctor. Dozens of doctors taking patients will not accept me as a patient, not even other doctors in the same practice, had in 2 years missing 2 entire discs only gotten 1 prescription for pain from him that I made last like 4 months before i decided I'd probably be able to sleep if i went to pain management. So I don't even ask for pain meds, don't want them, took myself off because I'd rather be in pain but here is the kicker no one will take me as patient because i had been in pain management. I would of never been in pain management of I had gotten surgery in a timely fashion. We are in a catch 22..I being disabled and 55 can not get any medical care except through emergency services because I was injured and needed care the entire.medical.community has left.me to die or go to emergency To manage blood pressure, heart burn, a cold, ear infection or other health issues. Can't get a referral to specialist for obvious skin cancer and other health issues. Woot America
Best comment on page, it's fundamentally unlawful, immoral and defies common sense to make a plant illegal, the plant pre-exists humanity and written law.
I can’t agree more! Why do people have to suffer through additional, needlessly complex barriers and bureaucracy to simply obtain some semblance of pain relief?? 😡😡😡😡
@@terrapinflyer273 They'll ban sugar as a 'precursor - product'... "Hey Buddy! Did you hear the news? Customs found a container down the docks with 500 kilos of sugar in it!" "Oh Yeah?! So, what, is that 'sugar', like Cocaine? _'Brown'_ sugar, y'know, like Heroin? Or we talking _sugar_ sugar, here? Like, you know, what they _make_ the Heroin out of?!" "Tell you the truth, Pal, there was a time when I could have told you; now? I don't even know any more!"
I have absolute no idea why I’m watching this video. The algorithm selected it for bedtime, probably due to the soothing combination of words I don’t understand. I missed all biology and chemistry in school. Good night.
Poppy seed is nutritious and stores well. Poppy is as desirable as wheat as a food crop. I recall reading an encyclopedia article that suggested that ancient human beings cultivated poppy as a food crop before they cultivated wheat.
Poppies also grow well in poor soils. You used to be able to get viable poppy seeds from Asian markets very cheaply. It has all kinds of colors, but the flowers don't last long. ❤
Heroin today is nothing like it used to be in the 80s and 90s . Its mostly cut with more crap than ever. I was a heroin addict for over 25 years,i have been clean for just under 2 years, one of the reasons i stopped because the heroin was so poor.
Same here. When they started cutting it with fent. Can't stand that stuff. Would make me vomit for a whole day and I barely did enough to feel it. So I ended up quitting.
I took pharmacology in college 50 years ago, and I spent a career in healthcare regulation. Pharmacologically, opioid does not include only synthetic substances which mimic natural opiates. Opioids are substances which act at opiate receptors, including both natural and synthetic opioids. Further complicating things for American viewers, U.S. controlled substance laws defines opiate and opioid as interchangeable, to include all opioids, both natural and synthetic. 21 USC 802(18).
Haha 😂 my thoughts exactly, plus the price would skyrocket… hang on, already seen a bit of a price hike over the past few years… apparently a bit of a shortage caused by bad harvests but this video might explain why 😅
Only because you all allow your government to punish the majority for the actions of the extreme minority... moronic way of life been proved wrong a million times sudafed actually worked but now we use some garbage because ThEy MiGhT MaKe MeTH meanwhile hundred million pounds of lab grade meth being imported monthly and the same government turn a blind eye for a cut LMAO
No idea what you are talking about -- We are professional biochemists doing research for scientific purposes. I guess your laboratory has been nicknamed 'parole' as some sort of joke...or something like that~😏😇🤨🙂
Me thinking to myself… With all of the tables available concerning “It’s being grown here, and converted to that, to be sent over there, unless you consider this…” That’s some pretty detailed data, for a “Drug Scourge” that’s reportedly impossible to control…
I'm honestly surprised that the yeasts for these processes haven't been leaked onto the black market yet. The patents came out in the early 2000s, I want to say that the hydromorphone variant was in the news in 2007 but I could be misremembering.
@@s70rk not profitable for industry but it's worthwhile for someone who needs strong painkillers and can't get them because of Perdue's awful business practices. Or for black market reasons since strong opiates and semisynthetic opioids sell for a dollar per milligram or even more.
They honestly don't even need to be leaked. As long as you are clean and patient making your own version in a home lab is entirely possible. We probably haven't heard of it because it's likely illegal.
A lil unrelated, but I saw a post a while back about a lichen that biosynthesizes 5-MeO-DMT, N,N-DMT, and and I think psilocybin, tho 4-HO-DMT (psilocin) would make more sense in my mind. I didn’t do a lot of research so idk the legitimacy, but I find the concept cool regardless
Get the mRNA that codes for the enzymes that make it. Convert to DNA and add to a guide seeker. Use Crisper to insert the genes into a convenient insertion point. Add something harmless that is an indicator that the graft took. They have done it with lots of other drugs already. If you want amine chemicals you need to feed the yeast ammonia and amino acids to get good yeilds. ❤
I had no issues with any of the alkaloids in the opium. I used poppy tea from dried pods from 2004-2016, twice a day from a cold water extract. Went through about 300$ of pods every 12 days. The poppy tea was quite reliable, and the dose would provide the same feeling and length with minimal dose increases over the years. The powerful euphoria was mostly felt in large muscle groups, especially thighs but it was a whole body buzz. Once buzz peaked about 45min in, it would hold for an hour, slightly reduce the euphoria then but would hold for 12-18 hours.
As with all opioids,.... didn't it start causing more problems than it was worth? After so many years of use, i can barely get euphoria from them anymore, and now i really want to quit
Also.....do you have any experience with kratom?. From 04 to 16 is a really long time when it comes to this stuff, that's about how long it's been for me
@@ShannonDove-sy7yeYeah, with regular use over time, developing a tolerance is inevitable. There isn't really any way around it except to slowly keep increasing the dose indefinitely, or take a break from it for a few days in between each use.
Myanmar (Burma) has completely overtaken Afghanistan in poppy farming, but Afghanistan had so much poppy stockpiled for processing into opium that they’re still supplying huge amounts of it. Eventually, Myanmar will be the main source, provided nothing changes.
@@joshsmith6955 That’s something to consider, but in this specific case it would be a good idea to watch what happens in the fight between the rebels and the junta.
that's interesting because opium is the dried latex, and the plant has to be still alive to milk it. How does one produce latex from a dried plant? Or do you mean they produce morphine from stockpiled straw?
in 2017 (grade 11) i saw that the head of harvard bioengineering had figured out the pathway of oxy from sugar using yeast and it was something like 1 dose in 326 000 gallons back then, intrigued af.
@@missstayc Maybe you , but I witnessed people on it get so stupid , they cant remember to shut doors , turn off burners , laughing at TV thats not turned on , etc , etc . Makes some people completely brain dead morons , its very dangerous to have idiots like that in your house or around kids .
I'm a 14 year recovered heroin addict, I've been prescribed methadone since 1999.. I'm currently taking 120mls daily. The only time I feel any different is when I go over about 30 hours between doses. I'm currently 46 years old & in all honesty I can't see me ever stopping.... But I never say never.! 😉
I have been on suboxone/Subutex since about 2019 and the beginning of this year, I got on methadone. It was by far the worst decision I have ever made. I was wrongfully arrested 8/15/24 a few hours before I was due to show at the clinic. I told every single officer I spoke with that I needed to get my medicine and that they are violating my rights but not one listened. I ended up in the infirmary. I was incarcerated for a week and it was hell. I've been out about 2 weeks now and I'm still going through detox. It's pure hell. I was only on 90mg and skipping every other day. Every time I think it's ended, it seems to start over again and then my skin hurts, I'm getting yawns and teary eyes. I pray you never have to experience the withdrawals of methadone as I am. Just be careful because that's definitely something they do not warn you about. Methadone is one of the longest detoxes there is!
I love how this particular video, "for some reason" has something like a thousand times the views of a lot of other videos on the channel (as in, it's amusing... I reckon this channel is worth a lot more views than it has received)
Most commercial poppy farms (for the seeds) sell the leftover hay for extraction of opiates. At one point in the uk, a farmer could get upto £10k a hectare for poppy crops! There aren't many poppy fields in the uk because of the licences required, even though the plants grow really well here!
Any opium derivatived opioid like heroin or oxycodone are technically opiates under some definitions. It really depends on who you ask. heroin is not synthetic it is a semi synthetic like oxycodone or hydrocodone which are debatably opiates. Synthetics are things like methadone, fentanyl, or Tramadol. Also there are more than “several” or six opium alkaloids infact there is 68 if I’m not mistaken.
@@stephaniebach__12-24 Suboxone is composed of two different opioids, one is a agonist and one a antagonist of the opioid receptors. Buprenorphine & Naloxone. Naloxone is a derivative of Oxymorphone which is derived from thebaine. Buprenorphine is derivatived directly from thebaine. So I would consider them opiates yes.
A few years back I read a paper where they had done the same but to produce diesel. if I remember right it was commercially viable. science is amazing!
Wow, its like being on RUclips before stupid ass Tik Tok existed. Thanks for the nostalgia trip and genuinely interesting video. Who would have known one of the most addictive substances on earth that you can buy in a grocery store legally as a food additive, can be chemically converted into one of the worlds most addictive drugs. DEA wanted every part of this too I see 💀
I thought the people that took over in afghan have outlawed any poppy production so now mainly production is in Mexico and the gaps are being filled by fet
Most good herion has always been made in Asia in burma and shit controlled by Chinese crime. They also have superlabs for meth and other drugs. Which are far far better than the trash from mexico. Europe does not have fent people consider it trash heroin is still king. These guys are far richer than cartels and far more lowkew.
I mean they say they outlawed it but I wouldn’t be surprised if they changed their mind simply due to how lucrative it is and the fact the Taliban don’t receive foreign aid like the previous government did, not to mention they’re still fighting people like ISIS and war requires money to wage.
I was once an opium enthusiast not to mention heroin was on the menu for years as well it’s taken a lot of my friends too. Despite all that I’d do it all again because regardless of the bad times there was good as well!
Actually opiates are from poppy and are the plants version of what chemicals are released by your opioid receptors, including heroin, while opioids are just chemicals that remove the inhibitors on your opioid receptors causing you to release what's stored and produced by your opioids receptors.
Who cares? The dudes in a tie do. And, as long as you choose to reside in a place where those dudes have jurisdiction, their laws are going to dictate what happens to you, whether you like it or not. It's fine to have a natural and/or religious view of the matter, but if push comes to shove... the dudes in a tie are going to have their way with you.
@@juzeus9 wrote, _"who gave them jurisdiction"_ Not who. What. What gave them jurisdiction is the practice of conquest. Though philosophically abhorrent, 'might makes right' is the way of the world. You can argue from a pedantic perspective, and you may be correct, but at the end of the day, matters of society are decided by the system implemented by power, not by armchair philosophers. To deny this is to deny reality as-it-is. And to deny reality as-it-is is to be delusional.
Wow imagine a future where all medicine is as easy and cheap as fermentation of sugar. Not just this but imagine how if good people got behind it how easy and cheaply people could receive chemical healthcare treatment
Would never happen in this world. Any potential tech, or drugs that would lose powerful people money get locked away, never to be heard of. It's 2024....it could have already been a very very different world decades ago. It's withheld.
It will not be the same as naturally derived opiates. It will lack the nuance of Mother Nature. The natural opiates will be regarded as a very valuable substance.
Cheaply? People? Nah, the prices will remain the same, the Labs making them will just take all the money, as they do now xD. Ozempic is one such example of how an easy to make medicine can be artificially limited in the name of patents.
@@JM-ym8mmsame with epinephrine. A huge ass vial is like $2 for a hospital, but a single use syringe has only gotten more and more expensive last I saw
This was super interesting and "easy to grasp and memorize" information! As a total non-chemist I can now understand the different drugs so much better :'D
Just be aware that there seems to be a lot of discourse over whether or not he used the definitions of opiate vs opioid correct. Info is always great, but make sure to get info from as many sources as possible to get the most accurate information, because everyone makes mistakes sometimes. The Drug Classroom is one of my favorite educational channels about this subject, tho plenty more exist too. Be safe, and have fun learning!!
In America, opium poppies are completely legal to own to grow and to sell, but what constitutes a crime is having somebody find sliced bulbs with wax in your trash or something if you’re processing your own little opium for yourself but you have to have a nighttime temperature blow 72° constantlygrowing up north works out pretty good. Florida does not grow poppies so that’s that.
Alot of people puke from opiates. You ALWAYS HEAR about people getting really loaded and the 1st thing they did was run to the bathroom and puke HARD!!! Then felt the euphoria and rush n stuff
Yes, it is very common for first-time users. However, the initial rush comes first, then puke, and then feel good. The initial rush/puke part is why a lot of people have tried it once (usually snorting or smoking), and it was enough to keep them from wanting to try it again, as the longer-term euphoria wasn't worth going through that first bit again. Based on my experience, this is a large majority of people. For others, especially people who have undiagnosed and untreated issues with depression, for example, the 'euphoria' is more of a 'wow, I feel really good, happy, etc.' and will continue to use it. The vomiting part is usually a one or two-time thing, and the rush is dose-dependent. As dopamine receptors adapt to the increase in dopamine, the user requires larger doses as tolerance increases over time.
@@intricatic if your not a big opiate user like oxy and percs or heroin, suboxone will have floating down the "Lazy River" as I like to call it. Have you ever went on a lazy river at a Waterpark you went to? 😅
Hi from Macedonia,my mama has cancer and is on fentanyl sticker,and now that i listened in the video why doctor's gave her fentanyl 😢😢😢!!! 5.08-5.20 AAHHH MAMA I LOVE YOU!!!!❤
Not quite accurate, people are not as connected to the land and are likely to make themselves sick even with some education on the use. The whiteish coating on regular poppy seeds is latex, people have exploited this and inevitably get a little high and a lot of sick. Or buy poppy pods for flower arrangements and get pesticides and the chemicals in the plant that make them puke for 2 days. Even things like St. John's Wort which is an antidepressant can interact with other over the counter or prescription meds to deadly effect. Natural does not mean safe, and an internet education should not suffice for formal education on the use of powerful chemicals, natural or not.
@@wendygore2709 😢we're tortured as some sort of sacrifice in the failed drug war. Torturing us though, converted a total of zero criminals to abstinence. Stop torturing us. No one deserves to Suffer. Ensure access to full agonist opioid access at the levels that work, so we can have a quality of life that's acceptable to US!!! End the controlled substances act End the failed drug war End the hyper stigmatization of opioids Free all Doctors arrested by the DEA On x #CPP #ChronicPain #PatientAdvocacy #painPatients #EndOpoidHystaria #OpoidsWork
1:29 heroin is in fact, made from a chemical change, but only one it is a derivative opiate technically not an opioid. A doubling of the morphine molecule if you would.
@@kevgorry1850 It doesn't double the strength of opium, that would suggest heroin is added to opium to increase potency. Opium is the natural resin that is cultivated from the poppy flower and naturally contains the opiates Morphine, codeine and thebine. To get heroin or Diacetylmorphine you must extract the morphine from the opium giving you a base form of morphine salt which is what would be used in a medical setting to make morphine tablets or to provide a morphine IV injection. After extraction you would put the morphine through an acetylation process bonding the morphine molecules at their carbon 4 bonds yielding Diacetylmorphine or heroin. There's also 2 other opioids that result from this process called 3-monoacetylmorphine (3-MAM) and 6-monoacetylmorphone (6-MAM) which tends to give heroin it's more psychedelic effects. There's also a way to alter the process where yields of 6MAM and 3-MAM are increased in final results.
There's a few articles about possibly making opium with home beer brewing kits. I was high af on poppy tea when I was reading it. Just Google it it was on the first page.
Weird how Thebaine (paramorphine) has risen to such importance post-discovery and marketing of the Bentley compounds. Traditional Poppies (P. somniferum) are so beautiful to grow-they still pop up by themselves annually in many established, older suburban gardens. 5:10 Fentanyl (a non-phenanthrene pethidine analog of extreme potency) is extensively used at the hospital where I work as part of intrathecal anaesthesia protocols. Fentanyl is so safe in hospital-yet so dangerous on the street, especially if not intimately mixed with its carrier.
This almost feels like a power point presentation....and yet that feels so comfortable! I don't need to constantly hit "pause" to glean the information i find interesting. Your style and pace are perfect. Concerning the subject matter, you might not receive as many "thumbs up" as are warranted. Clicking approval might someday get you put on a list, after all. I'm just saying...your work is better than you think.
Could the yeast break out into nature and contaminate food? those yeast bacteria are pretty resilient and suppose you find them on wild fruits like cherries, plums or slys ..
Also I don't think the owners of this yeast wants it to get lose so everyone can harvest it. I think they have genetically manipulated it to only be able to do this process in the presence of something they have in their labs/tanks.
This helped me finally understand that scene from "Master and Commander" where a patient under surgery moans and the surgeon says "It's just the laudanum speaking." Presumably, this is a reference to the sickness that high doses causes (rather than from pain from the wound itself).
I'll refer you to this legit dealer who has been my guide on my journey on DMT, dude also got all kinds of psychedelic stuffs in his store and ship directly to any location
That technology doesnt seem like it will be available any time in the near future. Those articles are sensational nonsense by people with no understanding of organic chemistry.
Great presentation by the way. I am not a chemistry expert by any means but was able to follow your explanation. Pity we cannot do this at home. If I was in pain I would like to be able to produce my own morphine and codeine and not have to pass thru the medical establishment for permission. I'm more than capable to administer this type of drug to myself with the necessary responsibility and if I died then at least I was not in pain.
I don't think anything will replace the pleasure provided by Heroin except orgasm, but orgasms don't last for hours. Fent and the others just don't hold a candle to it.
You mean opium? The feeling has a more organic “purple” hue to it than semi synthetic and synthetic opiates. Takes about ten dried pods crushed into powder and made into tea to satisfy a dope habit for about 12 hours. If you have a lot of land in Mexico or Afghanistan,you’re all set!
All opiates are indistinguishable in a double blind study. For instance heroin and morphine feel exactly the same but you have to find the right milligram to milligram ratio on each.
@@UnrelentingFaith Since heroin is rapidly deacetylated to 6-monoacetylmorphine (6-MAM) and then to morphine, drug addiction literature has long settled on the notion that heroin is little more than a means to deliver morphine and/or 6-MAM to the brain.
The tendency for vomiting from thebaine and other non psychoactive alkaloids in opium makes it ,opium,quite difficult to overdose from. If a user has no tolerance, they’ll likely vomit before it’s all absorbed. If a tolerance is present in a user, that in itself would also be a hinderance to overdose on top of the thebaine. Laudanum is problematic because it has large amounts of opium dissolved into a liquid and therefore a very large amount of morphine and codeine. Much more than just opium dissolved into a tea. It’s really beyond me why opium is illegal. If it were legally available, just by growing one’s own supply,fentanyl and heroin market would be reduced drastically. Humans have been using opium for at least 10k years. It was never much of a problem until modern drug laws were passed. Immediately, the most concentrated and potent and therefore addictive and deadly versions of the drug(opioids)were being smuggled and sold on the black market for astronomical profit margins. It’s not a mysterious phenomenon.
I would love to agree and on paper some of what you said makes sense but from over a decade of personal experience with different forms of opium from smoking and orally ingesting refined opium to drinking my fair share of unrefined poppy pod and seed brews what youve said is just not the case at all (do not underestimate the potency of poppy tea, its often more intense than smoking the refined product and a single dose lasts upto 24 hours with a peak that lasts about 6-7 hours).
The nature of Opiate addiction leads addicts to push things as far as possible everyday, once youve experienced nodding out on huge doses its the only way you can feel satisfied, anything less than nodding out for hours on end everyday no longer satisfies leading the addict to skirt the edge of overdose on a daily basis in order to achieve a nod, as they do this they also compensate for the ever growing tolerance with larger doses. Poppy tea is especially dangerous for overdose due to not just the drastic variation in potency from batch to batch but also due to its incredibly long half life leading to a buildup in your system if you redose within 24 hours of you original dose, I have experienced more than one overdose from Poppy tea due to these reasons and my tolerance was incredibly high from Oxycodone use back then. The other issue with poppy tea overdose is the fact that the peak of effects lasts for upto 7 hours and Nalaxone only works for about an hour meaning you constantly need to re-administer naloxone for many hours until the peak ends and breathing starts to return to normal, this means the user will be in precipitated withdrawal for upto 8-10 hours which is dangerous in and of itself. Another point Id like to make is the fact that tolerance to the different effects of Opioids rises at significantly different rates, tolerance to the nausea increases faster than any other effect whereas tolerance to the respiratory depression increases slower than any other effect including analgesia and subjective euphoria which also counters your point.
Id also like that add that Ive actually overdosed on Thebaine due to the recall of toxic poppy seeds that were circulated in stores around Australia in 2022 and mistakenly sold as papaver somniferum. While the Thebaine caused major convulsions and muscle spasms along with tachycardia and high blood pressure among other negative effects I didn’t have a single hint of nausea and didn’t throw up at all. This is actually the event that got me to finally quit opioids as poppy seeds and pods are the only source of opioids I have available to me at this point in my life and I dont want to risk another toxic batch.
I used to drink poppy tea quite a bit. I got a batch of seeds once ( Seed tea, this was the last time I used it ) that had what I suspected of high amounts of thebaine. It was giving me LOTS of anxiety and seizure like jerks when I would try to sleep . Like little mini seizures, was this from thebaine? It was *really* scary
@@mvmusic8467 Don’t drink as much poppy tea. Yes it DEFINITELY is stronger than smoking it. At some point you have to use judgement. There’s a ceiling effect as you only have so many opioid receptors. Some people will push themselves beyond reasonable doses on anything. Take alcohol for example. My point is, making it illegal has just made opiates more and more dangerous. It’s going to be much more difficult to push your luck with opium than it is with fentanyl. You used oxycodone. That’s where your tolerance came from. If you grew up in a culture where opium was more understood and available legally, you likely wouldn’t have learned to do as much as humanly possible every time you were lucky enough to get it in your hands. As far as the half life goes, it lasts the same as morphine because that’s what it is. It’s just not refined down to its active ingredient which provides a buffer. I’m sorry you had to experience thebaine that way. Definitely be sure about what you’re taking. It’s still much easier to determine proper poppy plants than it is to guess what’s in the white powder or black tar that is currently easily available in every community. If you do use opiates or any drug again, always remember that they are much more effective and safe if used in moderation. That includes alcohol and cannabis.
@@Aspiring-Hobo Idk it could have been. It also could’ve been contaminated with any number of toxic substances or bacteria.Be sure you know what you’re ingesting. Tea made from seeds isn’t likely to be very good even if it were a safe batch. Use dried pods from garden poppies. You can grow them in most places as long as you don’t plant a field and start producing narcotics. It’s the last part that gets you in trouble so be careful.
You sound like you're in active addiction. Habitually taking opium and it's derivatives is certainly not benign. Just because something is natural doesn't mean it's better for you
Hello boys, welcome to the watchlist.
😂. But seriously I’m just here cause I find it fascinating what human beings are capable of.😮
I'm already on it, this video is just par for the course for me.
Me too comrade 😅@Wardaddy51-50
This is what I get for watching Andrew huberman about how bad sugar is for you, the algorithm sends me to this as a logical next step
@insidiousmaximus
Ah, Andrew! So much good info!
Alas, the "list". What's a nonconformist to do these days?
one of those videos and channels where its like old RUclips. It hasn't blown up, no bots, no politics, and no bizarre arguments. Just people interested in the topic and discussing it. Nice.
Hi lo, I am human, vote Gop,because Ice cream doesnt have bones.
@@Bozemanjustin Ice cream can be tainted with bones because of marshmallows so ice cream free of bones depends upon added ingredients. Only home made can be determined to be made from marsh mallow plant instead of animal byproducts.
Dont forget all the wannabe comedians in the comments and people saying "bro" before a cringe sentence
@@Skitdora2010 but animal byproducts make purple the added ingredients
@@Chillinn33Yes true.They can b lil.Annoying if read
.Opium Tincture.was As good as Garlic./Monoclonal.Antibodies.all in 1.but no more sick.of it Lit..
Clicking on this video, I was hoping for a simple recipe. Something like "Add 100g of sugar to 1l of water, bring it to a boil, add a pinch of salt, stir 3 times to the left, 7 times to the right, say a magic spell and poof you got a pot full of Vicodin."
Still very interesting though.
Lmaoo right, damn click bait
But why did you think that? It seems really silly and naive tbh. Aren't we all silly and naive?
How did we get here, anyway...
Vicodin? Mostly asprin in that crap. Im crossing my fingers for the end of the failed "war on drugs" imagine just brewing your own dope. I'm hoping for a very different looking future
@@lefthookouchmcarm4520I mean the thumbnail text says “opiates brewed from sugar” making it sound pretty simple, like brewing a cup of tea.
But if it was that easy sugar would be illegal
@@Machinesofdrunkenhate well, it's technically, specifically, acetaminophen rather than aspirin - Vicodin is by definition hydrocodone and APAP, though there are other preparations containing NSAIDs like Ibuprofen and maybe Aspirin, but I'm guessing they're sold under a different trade name. Also you can remove the Tylenol and isolate the hydrocodone in like 20 minutes. Hydrocodone on its own is perfectly fine, its strength is either on par with or slightly below that of morphine on a mg per mg basis, I don't recall off the top of my head, but nothing really to turn your nose up at.
Instructions unclear I now have 2 tonnes of moonshine
That was good! Thanks for the laugh!
I'm trying to work my way backwards from where you're at
Shit bro...I just left a Psychadelic page....left with 2 tonnes o Mushrooms..
We should meet..😂
😂😂😂
Lollĺllllll
I used to live where they grew opium poppies on farms to harvest the seeds. These were for bakers to put on hard rolls and bagels etc. You know, those tiny black seeds. Birds spread them all over the area. There were poppies growing through the cracks in the sidewalk, along the train and trolley car tracks, just about every open space where weeds were growing. I don’t know what type of poppies they were but they looked exactly like the photos on this video. I would go first thing in the morning for a walk and slice the pods along my route. I had learned when and how to do it. In early afternoon I would retrace my steps and by then the white latex had turned black. I would harvest it, roll it into a little ball, which grew bigger day by day during the season. I would pinch off a tiny bit, and either dissolve it in a cup of tea or just swallow it. I got stoned as hell! Lasted all day. 😁 this was in Europe. Where I’m not going to say. The poppy seed industry no longer exists thanks to the do gooders, but our friends the birds have spread it all over the place.
Not in Wales eh?
Papaver somniferum is what is grown for bread seed and baked goods in Czech republic,Hngary and Poland and it contains both morphine and codeine, it's not very different from afghani or turkish poppies really. They can be and are used to make opium and other drugs. There was a fad of buying blue poppy seed in bulk from groccery strores and washing the seeds with water to recover the small amount of latex leftover on the seed from mechanical harvesting. it worked to one degree or another with pretty much any store bought poppy seed but was dangerous due to never knowing the concentration of the solution and people overdosed a few times
and thank you for pointing out that poppies don't need "good farmland" as claimed by the video and will grow in various soils anywhere it can get a foot hold and a little water occasionally. othere than they absolutely hate to be transplanted or have their roots otherwise disturbed poppies are failry easy to grow as an annual in almost all of north america,europe,the middle east,africa and asia. There are also signifigant poppy farms in Tasmania south of Australia.
the video also fails to mention that cannabis is a major crop in afghanistan that requires irrigated good land or fertilizer to produce well whereas poppies and wheat require less water so they are really competing for second place not first
Sounds like the Czech Republic 😅
I used to buy dried pods online and grind them up and eat it like oatmeal. Wasted all day long
They grow in many community gardens in the USA.
I'm looking forward to Nilereds next video
Doubt
@@gonelucidit’s a joke
Whats the joke?
Hahahaga 😮so funny 😂
Lmao, nice one
I had a friend, years ago that would make poppy tea from dried bulbs. I don't know the recipe, but it was a nice calming sensation, no euphoria, etc, just a calm, snoozy drink, and apparently legal to make at the time. I won't say it tasted great, or good, or even easy to drink, but she did manage to make it taste better, and less bitter over time, to the point where it resembled a natural tea, than a curious concoction of chemistry. I suppose it would be more or less like the best possible situation with Kratom, without "the urge to purge". I really miss those days :) Peaceful talks, and face to face relationships with no walls, or anxiety in the way. What a wonderful gift that few people realize plants, and flowers have given us. It's really sad that feeling well, and healthy is on the edge of illegal due to abuse of these gifts.
This video is like how youtube first was, alot of nich information shared across the platform. Had a nostalgia flashback lol
@squibbelsmcjohnsonyea,its in the bot how you tube redirects you to more adds and toss the good stuff in lock box.😅
You tube and Google changed there arrymitic to show you lsearch results with more adds and barrie the your search stuff than they just read those searches over when you burn them out and never give you what you truly want.Nasty seeding triggering, redrecting,socal engineering attack since its attacking your searches aginst you.
Nostalgia like Eminem's new song Houdini LOL
@kennethvayo2933 ha ha. It is a dope song. I'm gunna go listen to it again, right now. 😁
@@spanky541 hell yeah 😎
As a molecular biologist, I can assure you there's no such thing as a dead end in this field. There are setbacks and delays, sure. Long stretches with no discernable progress being made. Months of head scratching and seemingly endless troubleshooting come with the territory.
But the tools and techniques of the trade are vast, and the ways in which they can be modified or combined are limited only by one's ethics and imagination.
Yup they can copy paste the genes to all kinds of things. Yeastie beasties would be the best host for making narcotics like morphine etc. Fungi have more helper genes and hardware inside for chemical synthesis than bacteria. ❤
Thats beautiful
So what is the end result should someone's ethics be flawed?
Beautifully worded
@@MarkWalmsley Mankind is clever enough to open the very gates of Hell if we're foolish enough to do so. With this tool and many others.
"brown sugar, how come you taste so good?" 🍻
“Golden brown, texture like sun
Lays me down, with my mind she runs”
Damn
@@RowShawnBow The stranglers?? Nice
True story
I seen the needle and the damage done alittle part of it in everyone but every junkys like a setting sun ( Neal young)
The nausea is a safety mechanism.
We have opiate receptors for a reason.
we also have androgenous opioids too. just saying. everyone seems to forget about runners high and the bodies ability to make it's own opioids.
@@Zeeboklown *endogenous . (endo= within) Androgen would be pertaining to male. Androgynous means sort of ambiguous sex at least in English
God blessed us to enjoy his gifts lol
And exactly as stated why is it OK for a runner to run for the high but not for the opium smoker to smoke for the high?
It's called broken reality. Rules for thee but not for me.
An indulger of food gets diabetes and its poor harry.
An indulger of heroin gets addicted and he is bad man.
If we weren't supposed to use opiates, we wouldn't have receptors for them.
Using this video for educational and research purposes for my own happiness
A lot has happened in this field since those two papers. One of the authors of the original 2015 paper went on to found the biotech company Antheia, who recently partnered with API manufacturer Olon Group to produce thebaine on a commercial scale. We’re actually quite close to seeing this technology potentially replace opium poppies.
Antheia also has some interesting patents regarding the improvements they’ve made to the process.
This is sick we need to leave nature alone and stop modifying to patent it
@@StarThistle-c7xyou’ve probably ate GMO food at some point during your week. just bcuz you don’t fully understand something, doesn’t make it inherently evil
@@StarThistle-c7x do you feel the same way about dog and cat breeds ?? All of them were genetically modified through selective breeding
Could be revolutionary...
In a few days, a lab could make a ton of heroin!
Way better than the fentanyl junk we get now.
A flood of high grade morphine and heroin, with no poppy fields necessary, just sugar and bioengineering.
Would make drug enforcement completely unenforceable.
@@BracaPhoto interesting, i will have to explore further..
This is eye opening. Its like an uphill battle to get people healthy again, and loving themselves
I genuinely hope you never, ever know how right you are.
You're kind of wrong about the definition of opioid. "Opioid" doesn't have anything to do with natural or synthetic: opioids are simply anything that interacts with the opioid receptors, and opiates come directly from opium poppies. All opiates are opioids, but not all opioids are opiates. Mitragynine and 7-hydroxymitragynine are both natural indole alkaloid opioids that are either consumed in or extracted from plant material, but they're not opiates.
The alkaloids in Mitragina speciosa dont't come from Papaver sp. Hence they're not opiates. He was not saying that they have to come from a plant to be opiates but they have to come from Papaver sp.
@@chrisbrent7487True, but that was mentioned, and you completely missed the point. The point was that the word "opioid" is used for any substance that interacts with the opioid receptors in the body.
@@huhdidwhat He wasn't suggesting that an opioid has to be synthetic or semi synthetic though, just that they are not a natural constituent of P. somniferum. The major alkaloids of M. speciosa are considered opioids and you are correct about that.
@@chrisbrent7487at least in the length of the video I’ve watched, he states “Opiate: extracted from opium, and Opioid: mimics natural substances from the opium plant (synthetic)”.
While heroin is synthetic, it’s of opiate structure, whereas like the other commenter is saying, kratom is organic and an opioid. What I’ve been taught is Opiates are any drugs from the opium poppy as stated, but also certain synthetic drugs that follow the same pattern of structure, like heroin, oxycodone, hydromorphone, etc. Opioid, however, is any drug that interacts with opioid receptors in the expected way, like kratom (Mitragynine and others), fentanyl, nitazenes, etc. An exception that I know of is salvia divinorum, because while its main chemical salvinorin a is a kappa opioid receptor agonist, it isn’t referred to as an opioid due to its atypical dissociative effects and lack of expected anxiolysis and analgesia, tho I find it kinda numbing and therefore analgesic at times.
A rule to rule to remember for anyone reading is all opiates are opioids, but not all opioids are opiates. Still confusing, but that helped me.
Please correct me if I’m wrong about any of this, but this is what I’ve gathered over the years of casual research as I’ve always been more interested in chemicals that lead to a state of psychedelia or dissociation, but I think I’ve learned a decent amount
I'm currently hooked on kratom.. it got me off heroin and helped me stop drinking which I'm thankful for but I've been on 4-5tsp x3 a day for about 4 years..
A few years ago I learned that growing poppy in America is totally legal so long as you don't process it.
I just got a few hundred seeds and am creating the compost for them this fall.
I am also going to start growing Aztec tobacco next year.
Beautiful flowers on very showy stems, a self-sowing treat for a garden. Both bumble bees and honey bees go crazy for the pollen. I've seen half a dozen rolling around in a single flower, a sight and sound that does the heart good. In my rainy climate they stay upright when wet, unlike, say, irises which tend to fall over. You will easily collect a pint of tasty seeds (expensive to buy) from a few plants. I don't understand why our narrator says that the plant is good only for the opiates. I hope you get good germination and have them for years to come.
@@stephencuffel4932 Thank you very much for the encouragement.
I'm looking forward to seeing how they do here in Florida.
I know that poppys want that initial cold snap early on. So I'm thinking mid October or November to sow and they should germinate throughout the winter. I guess they're like strawberries when it comes to cold snaps. They love em if they don't get too cold for too long.
The tobacco I do intend to harvest and smoke. I quit smoking cigarettes a few years ago and don't want to pick it back up but I want to use it how it was used back in the past. So small shallow bowl and like one hit from a peace pipe. The Aztec I grabbed is Nicotiana Rustica.
Neither were that expensive either.
I think the poppys were like 8$ for 100 seeds and that included shipping. The tobacco I think was about the same price as well for 100 seeds and shipping.
Read up about growing them-they actually prefer a poor dry soil.
There are several legal Salvia strains as well, they're mostly native to Utah so they will enjoy the same dry soil
How do you make your mulch?
I stumbled randomly around this video, due to youtube algorithm. I worked professional as a nurse before switching to computer science and I was always interested in chemistry and biology. Even though I don’t understand the whole process due to lack of knowledge it's incredible to see what is possible. So I guess thank you for your video!
clicked out of curiosity now realize i'm on a list or two.
the same, good job I dont have garden
Lol😂 same. Just scrolling. Saw it. Is this clickbait? Curiosity listed the cat.
ruclips.net/video/WUQDsDgJGpQ/видео.html
Welcome to the club
It's the internet. You're being listed all the time.
Just started watching but already saying, having an alternative source of opiates/oids might come in handy in a shtf situation where painkillers might become unavailable.
Here it is legal to grow opium poppies, it is just the use and extraction that is illegal. And it is same rules in most of the world. I have been thinking the same that it might be wise to have some opium plants just in case something happens and no painkillers is available anymore (either from war or more likely bureaucrats closing down on mediacal opiate use )..
@@a64738 lucky. I don't think they'd grow in tropical lowlands. I've read about kratom but sourcing saplings are probably gonna be a pain
Kratom
@@stephenroldan5107mentioned this on my reply to a64738, that it's probably the only one that would grow in the tropics. Weird that my comment seem to just have disappeared.
You'd still need the GMO yeast and a synthesis process to turn the precursor into final product.
Two years ago, my mother in law was prescribed opium as she was entering chemotherapy.
She gave the bottle to me.
At that time, I "had been around the block" regarding everything available on the street. It was a 25 year experience that had been ceased for ten years when she gave me the bottle.
I took a 10ml dose from the bottle. My first dose felt "cleaner", if that makes any sense, and I had no stomach issues. It felt like a 10mg percocet, but "cleaner".
The 150ml bottle lasted me a year. It was fantastic. No hangover, but I did recognize a tolerance by day three.
What country do you live in. I didnt know they prescribed opium. Your mother in law didn't take any of it?
@@JNB520 Neither did the pharmacist. In CO.
@@joeschmoe1776 lol, nice!
Mother opium is a beautiful feeling
Hangover? Is that a subtle term for "potential relapse into full fledged use & dependence"? Opiates don't produce "hangovers" e.g. alcohol, or in any conventional sense. It's only a matter of time before dependence on both a biological & conscious level occurs; "recreational, frequent use of opiates responsibly forever" is a lie. An impossibility. The closest thing to a "hangover" is the painful reaction created by newly created µ & related receptors emptying & resulting in the mind reeling in agony & imbalance to some degree. Manifesting as mere irritability, discomfort/craving, all the way to utter dysfunction & excruciating withdrawal from the brain being perpetually chemically rewired. Each time anyone ingests an opiate agonist, a permanent change is created in the brain from which it never heals. There's no "reset" button, just dogma & wishful thinking.
Opiate agonists, alcohol, benzodiazepines (created in large part as substitutes for what natural opiates were once used for, before Harry J Anslinger & his goons got the US & much of the world to outlaw them), barbiturates, alcohol... All have one thing in common: They create chemical changes in the brain on the level of DNA. Much in pop culture glorifies the use of alcohol & hard drugs, baiting & hooking more souls into a burgeoning black market in the US & increasingly the world over. The DEA (among others), in defiance of basic human rights & our constitution, work hand in hand with them, creating a devastating blight on society. DEA ensures the black market for "scheduled" or illegal, pernicious commodities thrives by adding a heavy element of risk targeting the upper-middle to lower part of said market, ensuring it's very existence & survival, along with it's perpetual bloodshed. The illicit market provides often lethal products leading to untold suffering & death to Americans who pay an egregiously inflated price for a usually potentially lethal, often extremely harmful, adulterated & unfit end product. This also helps keep the US's world record prison population growing & often over capacity. 20% of the world's prisoners are in the US, with only roughly 5% of the word's population.
Statistics show the very existence of DEA & their futile, deadly war on drugs result in yet more consumers for the black market, simply by taking advantage of youthful rebellion & human nature: telling people they aren't allowed to ingest something only ensures many defy the unreasonable imposition & do the opposite. Sad but true.
Great video. as a perc user by RX this to me is exciting. Pain is not fun.
Yeah don't hold ya breath!
This sounds good, OR, we could stop acting like tyrants, use the gifts nature has provided and stop making people in pain jump through hoops to get the relief they need.
Yep. My thoughts exactly
Oh it's worse than that. I had a fight with my insurance company that lasted 4 years(thanks Obamacare) to get a fusion, by then end of the 4 years i was permanently disabled and had been on pain management a few years. Post 2 surgeries I took myseldnoffnof.pain management where my monthly bill was 250 a month and I never failed a urine test nor missed a pill in the monthly count. Then my primary care physician moved to be close to his kids in college. I then spent 3 years searching for a family or primary care doctor. Dozens of doctors taking patients will not accept me as a patient, not even other doctors in the same practice, had in 2 years missing 2 entire discs only gotten 1 prescription for pain from him that I made last like 4 months before i decided I'd probably be able to sleep if i went to pain management. So I don't even ask for pain meds, don't want them, took myself off because I'd rather be in pain but here is the kicker no one will take me as patient because i had been in pain management. I would of never been in pain management of I had gotten surgery in a timely fashion. We are in a catch 22..I being disabled and 55 can not get any medical care except through emergency services because I was injured and needed care the entire.medical.community has left.me to die or go to emergency To manage blood pressure, heart burn, a cold, ear infection or other health issues. Can't get a referral to specialist for obvious skin cancer and other health issues. Woot America
Best comment on page, it's fundamentally unlawful, immoral and defies common sense to make a plant illegal, the plant pre-exists humanity and written law.
I can’t agree more! Why do people have to suffer through additional, needlessly complex barriers and bureaucracy to simply obtain some semblance of pain relief?? 😡😡😡😡
That'll be the day!!!!
How much you wanna bet that the cartels will be using this for production long before it gets approved to be used by pharmaceutical companies?
In today's news, it appears the entire world is suffering from a sugar shortage...
@@terrapinflyer273 They'll ban sugar as a 'precursor - product'...
"Hey Buddy! Did you hear the news? Customs found a container down the docks with 500 kilos of sugar in it!" "Oh Yeah?! So, what, is that 'sugar', like Cocaine? _'Brown'_ sugar, y'know, like Heroin? Or we talking _sugar_ sugar, here? Like, you know, what they _make_ the Heroin out of?!" "Tell you the truth, Pal, there was a time when I could have told you; now? I don't even know any more!"
They’ll pioneer it
That would be better than them producing all that fetanyl
@@RicArmstrong Unfortunately, yes.
I have absolute no idea why I’m watching this video. The algorithm selected it for bedtime, probably due to the soothing combination of words I don’t understand. I missed all biology and chemistry in school. Good night.
Me neither. I clicked on the next video while working and hope I am not on some list now😂.
The algorithm wants you to become a junkie, be cool, obey the algorithm man!🎉
Poppy seed is nutritious and stores well. Poppy is as desirable as wheat as a food crop. I recall reading an encyclopedia article that suggested that ancient human beings cultivated poppy as a food crop before they cultivated wheat.
Poppies also grow well in poor soils. You used to be able to get viable poppy seeds from Asian markets very cheaply. It has all kinds of colors, but the flowers don't last long. ❤
Heroin today is nothing like it used to be in the 80s and 90s . Its mostly cut with more crap than ever. I was a heroin addict for over 25 years,i have been clean for just under 2 years, one of the reasons i stopped because the heroin was so poor.
Same here. When they started cutting it with fent. Can't stand that stuff. Would make me vomit for a whole day and I barely did enough to feel it. So I ended up quitting.
Same here. I don’t even think you can get the real McCoy any more.
I wish I could try Heroin from the 80's or 90's. Man i'm jealous of you guys
Same
yep
I took pharmacology in college 50 years ago, and I spent a career in healthcare regulation. Pharmacologically, opioid does not include only synthetic substances which mimic natural opiates. Opioids are substances which act at opiate receptors, including both natural and synthetic opioids. Further complicating things for American viewers, U.S. controlled substance laws defines opiate and opioid as interchangeable, to include all opioids, both natural and synthetic. 21 USC 802(18).
Was going to comment this.
This was really cool to hear, being walked through why it would be helpful for industries to be able to produce opiates as opiods from sugar.
Great!! Now I'm gonna have to show my ID when buying brown sugar. Good job nummie.
Haha 😂 my thoughts exactly, plus the price would skyrocket… hang on, already seen a bit of a price hike over the past few years… apparently a bit of a shortage caused by bad harvests but this video might explain why 😅
@@MMelanie963 Anyone consider the possibility that this is total PROPAGANDA, to sell more SUGAR? They are known to DO scumbag things like that.
I'll have to start sourcing my E.Coli on the black market too dammit.
Only because you all allow your government to punish the majority for the actions of the extreme minority...
moronic way of life been proved wrong a million times
sudafed actually worked but now we use some garbage because ThEy MiGhT MaKe MeTH
meanwhile hundred million pounds of lab grade meth being imported monthly and the same government turn a blind eye for a cut LMAO
@@wobblyboost 😁 scrape the toilet bowl or try raw chicken juice 😘👌
Everyone on parole watching this 👀
😂
No idea what you are talking about -- We are professional biochemists doing research for scientific purposes.
I guess your laboratory has been nicknamed 'parole' as some sort of joke...or something like that~😏😇🤨🙂
Me not on parole looking at this 👀
Me thinking to myself… With all of the tables available concerning “It’s being grown here, and converted to that, to be sent over there, unless you consider this…”
That’s some pretty detailed data, for a “Drug Scourge” that’s reportedly impossible to control…
@@f1nch1312 lmao I feel you
I'm honestly surprised that the yeasts for these processes haven't been leaked onto the black market yet. The patents came out in the early 2000s, I want to say that the hydromorphone variant was in the news in 2007 but I could be misremembering.
Maybe they have leaked but this video makes it evident that they aren't profitable. So why bother with them?
@@s70rk not profitable for industry but it's worthwhile for someone who needs strong painkillers and can't get them because of Perdue's awful business practices. Or for black market reasons since strong opiates and semisynthetic opioids sell for a dollar per milligram or even more.
@@s70rk commercially for pharma, they aint getting 80k per kg.......
@@s70rk also not everyone can grow poppies, aload of 25l vats are more reasonable
They honestly don't even need to be leaked. As long as you are clean and patient making your own version in a home lab is entirely possible. We probably haven't heard of it because it's likely illegal.
There's also a strain of yeast developed that produces psilocybin
And there's one for THC as well. I think there's no organic molecules that a gmo yeast wouldn't be able to produce
Nice
Ergot is the fungus from rye wheat that's synthesised into LSD.
@@MHLivestreams lots of free contaminated rice and wheat available for extraction from grainerys
A lil unrelated, but I saw a post a while back about a lichen that biosynthesizes 5-MeO-DMT, N,N-DMT, and and I think psilocybin, tho 4-HO-DMT (psilocin) would make more sense in my mind. I didn’t do a lot of research so idk the legitimacy, but I find the concept cool regardless
Sweet sweet sugar,come to Papa!
I think this video will take off!
I had a blast, and learned along the way.
Time to get my CRISPR ready.... think I'd rather grow poppies though.. that seems like a lot of work lol
Get the mRNA that codes for the enzymes that make it. Convert to DNA and add to a guide seeker. Use Crisper to insert the genes into a convenient insertion point. Add something harmless that is an indicator that the graft took. They have done it with lots of other drugs already. If you want amine chemicals you need to feed the yeast ammonia and amino acids to get good yeilds. ❤
U won’t find any unwashed seeds. This is ur best bet
@@cyma-zw2ttthen you’re not looking in the right places, plenty of quality seeds available online
@@cyma-zw2tt lol. you can find plenty of unwashed seeds. i buy them frequently
Watching for a friend
Everyone is...
The body can process raw cane sugar extremely well, the body is a natural distilling machine, brilliant channel very educational thanks,😮
I had no issues with any of the alkaloids in the opium. I used poppy tea from dried pods from 2004-2016, twice a day from a cold water extract. Went through about 300$ of pods every 12 days. The poppy tea was quite reliable, and the dose would provide the same feeling and length with minimal dose increases over the years. The powerful euphoria was mostly felt in large muscle groups, especially thighs but it was a whole body buzz. Once buzz peaked about 45min in, it would hold for an hour, slightly reduce the euphoria then but would hold for 12-18 hours.
As with all opioids,.... didn't it start causing more problems than it was worth? After so many years of use, i can barely get euphoria from them anymore, and now i really want to quit
Also.....do you have any experience with kratom?.
From 04 to 16 is a really long time when it comes to this stuff, that's about how long it's been for me
@@ShannonDove-sy7yeYeah, with regular use over time, developing a tolerance is inevitable. There isn't really any way around it except to slowly keep increasing the dose indefinitely, or take a break from it for a few days in between each use.
World's most wheat produced not in Ukraine but in China, India, Russia, more than 5x greater than Ukraine. great analytics. 80lvl. Unbiased
Would be good for preparing when there is no medical help any more ALL knowledge of plant medicine would be priceless.❤
Myanmar (Burma) has completely overtaken Afghanistan in poppy farming, but Afghanistan had so much poppy stockpiled for processing into opium that they’re still supplying huge amounts of it. Eventually, Myanmar will be the main source, provided nothing changes.
Until the US invades somewhere. Then where we invade become highest producing country. Or region.
@@joshsmith6955 That’s something to consider, but in this specific case it would be a good idea to watch what happens in the fight between the rebels and the junta.
@@geeekaaay5425 specifically this case, yes. I agree. I was just making a little quip that anywhere the US invades... The poppy follows
@@joshsmith6955 Without question. I’m sure they’re monitoring the situation as well and will respond accordingly.
that's interesting because opium is the dried latex, and the plant has to be still alive to milk it. How does one produce latex from a dried plant? Or do you mean they produce morphine from stockpiled straw?
in 2017 (grade 11) i saw that the head of harvard bioengineering had figured out the pathway of oxy from sugar using yeast and it was something like 1 dose in 326 000 gallons back then, intrigued af.
really good stuff, straight to the point and informative without bs, they are surely making big amounts now
All drugs should be legal and redely avalable for adults
Duh
We all agree
Why not , the most damaging ones are legal , alcohol and pot . One causes car wrecks and one causes stupidess .
@@marcchaffee7751 nah pot just makes U lazy
@@missstayc Maybe you , but I witnessed people on it get so stupid , they cant remember to shut doors , turn off burners , laughing at TV thats not turned on , etc , etc . Makes some people completely brain dead morons , its very dangerous to have idiots like that in your house or around kids .
⚛️👏⚛️ Bravo! We really need to open source this kind of research as much as possible!
I'm a 14 year recovered heroin addict, I've been prescribed methadone since 1999..
I'm currently taking 120mls daily.
The only time I feel any different is when I go over about 30 hours between doses.
I'm currently 46 years old & in all honesty I can't see me ever stopping.... But I never say never.! 😉
I have been on suboxone/Subutex since about 2019 and the beginning of this year, I got on methadone. It was by far the worst decision I have ever made. I was wrongfully arrested 8/15/24 a few hours before I was due to show at the clinic. I told every single officer I spoke with that I needed to get my medicine and that they are violating my rights but not one listened. I ended up in the infirmary. I was incarcerated for a week and it was hell. I've been out about 2 weeks now and I'm still going through detox. It's pure hell. I was only on 90mg and skipping every other day. Every time I think it's ended, it seems to start over again and then my skin hurts, I'm getting yawns and teary eyes. I pray you never have to experience the withdrawals of methadone as I am. Just be careful because that's definitely something they do not warn you about. Methadone is one of the longest detoxes there is!
This has been my first video from this channel. Excellent in all ways. Now on my watchl ist.
I love how this particular video, "for some reason" has something like a thousand times the views of a lot of other videos on the channel (as in, it's amusing... I reckon this channel is worth a lot more views than it has received)
I just found your channel and i am already in love.
Those 15 mins felt like one. Very good presentation of an interesting topic.
Most commercial poppy farms (for the seeds) sell the leftover hay for extraction of opiates.
At one point in the uk, a farmer could get upto £10k a hectare for poppy crops! There aren't many poppy fields in the uk because of the licences required, even though the plants grow really well here!
Any opium derivatived opioid like heroin or oxycodone are technically opiates under some definitions. It really depends on who you ask. heroin is not synthetic it is a semi synthetic like oxycodone or hydrocodone which are debatably opiates. Synthetics are things like methadone, fentanyl, or Tramadol. Also there are more than “several” or six opium alkaloids infact there is 68 if I’m not mistaken.
And Suboxone I believe
@@stephaniebach__12-24 Suboxone is composed of two different opioids, one is a agonist and one a antagonist of the opioid receptors. Buprenorphine & Naloxone. Naloxone is a derivative of Oxymorphone which is derived from thebaine. Buprenorphine is derivatived directly from thebaine. So I would consider them opiates yes.
@@stephaniebach__12-24suboxone is a brand name for the medication called bupenorphine
Brilliant. Very interesting and informative. Well explained too. Thanks.
A few years back I read a paper where they had done the same but to produce diesel. if I remember right it was commercially viable.
science is amazing!
Wow, its like being on RUclips before stupid ass Tik Tok existed. Thanks for the nostalgia trip and genuinely interesting video. Who would have known one of the most addictive substances on earth that you can buy in a grocery store legally as a food additive, can be chemically converted into one of the worlds most addictive drugs.
DEA wanted every part of this too I see 💀
I thought the people that took over in afghan have outlawed any poppy production so now mainly production is in Mexico and the gaps are being filled by fet
Most good herion has always been made in Asia in burma and shit controlled by Chinese crime. They also have superlabs for meth and other drugs. Which are far far better than the trash from mexico. Europe does not have fent people consider it trash heroin is still king. These guys are far richer than cartels and far more lowkew.
I mean they say they outlawed it but I wouldn’t be surprised if they changed their mind simply due to how lucrative it is and the fact the Taliban don’t receive foreign aid like the previous government did, not to mention they’re still fighting people like ISIS and war requires money to wage.
I was about to buy lots of sugar. Damn, i am disappointed. No happiness again.
I was once an opium enthusiast not to mention heroin was on the menu for years as well it’s taken a lot of my friends too. Despite all that I’d do it all again because regardless of the bad times there was good as well!
Actually opiates are from poppy and are the plants version of what chemicals are released by your opioid receptors, including heroin, while opioids are just chemicals that remove the inhibitors on your opioid receptors causing you to release what's stored and produced by your opioids receptors.
If only the same amount of research on this subject was done on Psilocybe mushrooms.
who cares if some dudes in a tie aprove it as legal or not. its a gift of nature
behold i have given you every seed bearing herb upon the face of all the earth. - god
Who cares? The dudes in a tie do. And, as long as you choose to reside in a place where those dudes have jurisdiction, their laws are going to dictate what happens to you, whether you like it or not. It's fine to have a natural and/or religious view of the matter, but if push comes to shove... the dudes in a tie are going to have their way with you.
@@RichardHarlos who gave them jurisdiction
@@juzeus9 wrote, _"who gave them jurisdiction"_
Not who. What. What gave them jurisdiction is the practice of conquest. Though philosophically abhorrent, 'might makes right' is the way of the world. You can argue from a pedantic perspective, and you may be correct, but at the end of the day, matters of society are decided by the system implemented by power, not by armchair philosophers.
To deny this is to deny reality as-it-is. And to deny reality as-it-is is to be delusional.
@@RichardHarlos that sounds more like slavery than jurisdiction
Wow imagine a future where all medicine is as easy and cheap as fermentation of sugar. Not just this but imagine how if good people got behind it how easy and cheaply people could receive chemical healthcare treatment
Would never happen in this world. Any potential tech, or drugs that would lose powerful people money get locked away, never to be heard of.
It's 2024....it could have already been a very very different world decades ago. It's withheld.
It will not be the same as naturally derived opiates. It will lack the nuance of Mother Nature.
The natural opiates will be regarded as a very valuable substance.
Cheaply? People? Nah, the prices will remain the same, the Labs making them will just take all the money, as they do now xD.
Ozempic is one such example of how an easy to make medicine can be artificially limited in the name of patents.
....you're putting too much faith in an industry science far more advanced in marketing than in medicine.
@@JM-ym8mmsame with epinephrine. A huge ass vial is like $2 for a hospital, but a single use syringe has only gotten more and more expensive last I saw
This was super interesting and "easy to grasp and memorize" information! As a total non-chemist I can now understand the different drugs so much better :'D
So yeah I subscribed!
Just be aware that there seems to be a lot of discourse over whether or not he used the definitions of opiate vs opioid correct. Info is always great, but make sure to get info from as many sources as possible to get the most accurate information, because everyone makes mistakes sometimes. The Drug Classroom is one of my favorite educational channels about this subject, tho plenty more exist too. Be safe, and have fun learning!!
@@bodi.mp3 thank you dude or dudette!
In America, opium poppies are completely legal to own to grow and to sell, but what constitutes a crime is having somebody find sliced bulbs with wax in your trash or something if you’re processing your own little opium for yourself but you have to have a nighttime temperature blow 72° constantlygrowing up north works out pretty good. Florida does not grow poppies so that’s that.
Underground, feed warm, grows like crazy especially when you play Stevie Ray Vaughn.😂
@@anthonymcnatt3799 yea true lightning and underground but that seems illegal since they are legal to grow but not a bad idea
Alot of people puke from opiates.
You ALWAYS HEAR about people getting really loaded and the 1st thing they did was run to the bathroom and puke HARD!!!
Then felt the euphoria and rush n stuff
Yes, it is very common for first-time users. However, the initial rush comes first, then puke, and then feel good. The initial rush/puke part is why a lot of people have tried it once (usually snorting or smoking), and it was enough to keep them from wanting to try it again, as the longer-term euphoria wasn't worth going through that first bit again. Based on my experience, this is a large majority of people. For others, especially people who have undiagnosed and untreated issues with depression, for example, the 'euphoria' is more of a 'wow, I feel really good, happy, etc.' and will continue to use it. The vomiting part is usually a one or two-time thing, and the rush is dose-dependent. As dopamine receptors adapt to the increase in dopamine, the user requires larger doses as tolerance increases over time.
I was taking suboxone for like four years. First time I took the stuff, I had the happiest vomit of my life. It was so weird.
@@intricaticyou must have taken too much suboxone, or waited too long to take it.
@@intricatic if your not a big opiate user like oxy and percs or heroin, suboxone will have floating down the "Lazy River" as I like to call it. Have you ever went on a lazy river at a Waterpark you went to? 😅
@@intricatici know exactly what u mean
Interesting! Love this type of content, do you have any other videos akin to this one? Thank you
A chocolate bar helps with body pain. It doesn't last long, but it does give you some relief.
Ahhhhh endorphins!!
No.
@DrDeuteron you are welcome to your own opinion. I suffer from a messed-up spine and knees. Do you suffer from chronic pain?
Hi from Macedonia,my mama has cancer and is on fentanyl sticker,and now that i listened in the video why doctor's gave her fentanyl 😢😢😢!!! 5.08-5.20 AAHHH MAMA I LOVE YOU!!!!❤
Great stuff I always loved just good quick (not rushed) informational content.
If it’s synthetic I understand outlawing it. But if it’s a natural plant it should be legal for the people. We’ve used plant medicines since forever
Not quite accurate, people are not as connected to the land and are likely to make themselves sick even with some education on the use.
The whiteish coating on regular poppy seeds is latex, people have exploited this and inevitably get a little high and a lot of sick.
Or buy poppy pods for flower arrangements and get pesticides and the chemicals in the plant that make them puke for 2 days.
Even things like St. John's Wort which is an antidepressant can interact with other over the counter or prescription meds to deadly effect.
Natural does not mean safe, and an internet education should not suffice for formal education on the use of powerful chemicals, natural or not.
Wild lettuce when harvested & prepped correctly, binds to the human opioid receptors
Only for a select few. For those of us w/severe chronic pain issues, it doesn't work 😢
@@wendygore2709 😢we're tortured as some sort of sacrifice in the failed drug war. Torturing us though, converted a total of zero criminals to abstinence.
Stop torturing us.
No one deserves to Suffer. Ensure access to full agonist opioid access at the levels that work, so we can have a quality of life that's acceptable to US!!!
End the controlled substances act
End the failed drug war
End the hyper stigmatization of opioids
Free all Doctors arrested by the DEA
On x
#CPP #ChronicPain #PatientAdvocacy #painPatients #EndOpoidHystaria #OpoidsWork
1:29 heroin is in fact, made from a chemical change, but only one it is a derivative opiate technically not an opioid. A doubling of the morphine molecule if you would.
The comment i was looking for
.acetil anhydryde is what u need known as AA
Dident now tht it doubles strength of opium
Heroin is metabolized into morphine. In the body
@@kevgorry1850 It doesn't double the strength of opium, that would suggest heroin is added to opium to increase potency.
Opium is the natural resin that is cultivated from the poppy flower and naturally contains the opiates Morphine, codeine and thebine.
To get heroin or Diacetylmorphine you must extract the morphine from the opium giving you a base form of morphine salt which is what would be used in a medical setting to make morphine tablets or to provide a morphine IV injection.
After extraction you would put the morphine through an acetylation process bonding the morphine molecules at their carbon 4 bonds yielding Diacetylmorphine or heroin.
There's also 2 other opioids that result from this process called 3-monoacetylmorphine (3-MAM) and 6-monoacetylmorphone (6-MAM)
which tends to give heroin it's more psychedelic effects.
There's also a way to alter the process where yields of 6MAM and 3-MAM are increased in final results.
Hi feds, I’m not watching this for scientific purposes, I want my brain to travel through a few different hundreds dimensions
Fascinating, i was wondering about biotransformation of compounds in the seeds via fermentation/baking the other week!
I brew beer.makes me wonder if you could do this at home if you had the yeast.
There's a few articles about possibly making opium with home beer brewing kits. I was high af on poppy tea when I was reading it. Just Google it it was on the first page.
no
Weird how Thebaine (paramorphine) has risen to such importance post-discovery and marketing of the Bentley compounds. Traditional Poppies (P. somniferum) are so beautiful to grow-they still pop up by themselves annually in many established, older suburban gardens. 5:10 Fentanyl (a non-phenanthrene pethidine analog of extreme potency) is extensively used at the hospital where I work as part of intrathecal anaesthesia protocols. Fentanyl is so safe in hospital-yet so dangerous on the street, especially if not intimately mixed with its carrier.
Isn't it true that pseudoephedrine also can be produced through fermentation in this manner?
Science man boldly pushes forward, unbothered by questions "should we really invent new ways to make fentanyl?"
RUclips recommended this to you to put you on a list.
Post this to me please and I'll be there for a conversation 😊
I’m confused by them “stopping” at the precursor thebaine to avoid creating usable opioids when if you stop 3 steps before it you get hydrocodone 😂
Check out the flowchart again, thebain is created before hydro
Can I use it to make my own pain meds? The gov't is more worried about junkies over people with chronic pain like me.
That’s exactly what a junky would say! Essentially ya can do anything if ya don’t get caught and are prepared for the consequences
@@bobhope4949lol ok whatever fool. You try living with failed spine surgery.
They are worried about you, they want you to suffer.
WOW!!! This is VERY interesting!!
I remember this I think it never went anywhere, thank you for the video ❤
This almost feels like a power point presentation....and yet that feels so comfortable! I don't need to constantly hit "pause" to glean the information i find interesting. Your style and pace are perfect.
Concerning the subject matter, you might not receive as many "thumbs up" as are warranted. Clicking approval might someday get you put on a list, after all. I'm just saying...your work is better than you think.
Could the yeast break out into nature and contaminate food? those yeast bacteria are pretty resilient and suppose you find them on wild fruits like cherries, plums or slys ..
Yes it has happened but wild yeasts tend to overpower the gm yeasts.
Yeast is not bacteria. Its a unicellular life form.
Also I don't think the owners of this yeast wants it to get lose so everyone can harvest it.
I think they have genetically manipulated it to only be able to do this process in the presence of something they have in their labs/tanks.
@@elishh8173 Oh, u mean like C ovid was? That worked out just as they planned.
Well made video! 👌 ❤
This helped me finally understand that scene from "Master and Commander" where a patient under surgery moans and the surgeon says "It's just the laudanum speaking." Presumably, this is a reference to the sickness that high doses causes (rather than from pain from the wound itself).
I was really hoping for a diy guide here.
I'll refer you to this legit dealer who has been my guide on my journey on DMT, dude also got all kinds of psychedelic stuffs in his store and ship directly to any location
They're on telegram as
I love Gardening 😊
auto brewery syndrome but with these 🤩
3d printing all pharmaceuticals in the near future. I heard about this about 5 years ago
That technology doesnt seem like it will be available any time in the near future. Those articles are sensational nonsense by people with no understanding of organic chemistry.
Further away than fusion. Hypothetically they are both sound.
Wait..... _What?_
*Wow!*
Very good video. Learned quite a bit and was very interesting. Keep up the good work!
WHO is NOT a health advocacy group but a for profit corporation traded on Dunn and Bradstreet
100 points for clickbait, make another one about opiates from water: a growing route
Get sugar opioids and wind up with diabetis lol
Great presentation by the way. I am not a chemistry expert by any means but was able to follow your explanation. Pity we cannot do this at home. If I was in pain I would like to be able to produce my own morphine and codeine and not have to pass thru the medical establishment for permission. I'm more than capable to administer this type of drug to myself with the necessary responsibility and if I died then at least I was not in pain.
I don't think anything will replace the pleasure provided by Heroin except orgasm, but orgasms don't last for hours. Fent and the others just don't hold a candle to it.
Just saying hello to the NSA watching me for clicking this video
We, humans, have the right to strive to get knowledge about everything.
(As long as it doesn't hurt anyone)
Sticking out my middle finger to them.
Hello!
All My comments are for educational information.
Has anyone tried this? And how does it compare to opiates like oxy and heroin? Tia
You mean opium? The feeling has a more organic “purple” hue to it than semi synthetic and synthetic opiates. Takes about ten dried pods crushed into powder and made into tea to satisfy a dope habit for about 12 hours. If you have a lot of land in Mexico or Afghanistan,you’re all set!
All opiates are indistinguishable in a double blind study. For instance heroin and morphine feel exactly the same but you have to find the right milligram to milligram ratio on each.
@@UnrelentingFaith Since heroin is rapidly deacetylated to 6-monoacetylmorphine (6-MAM) and then to morphine, drug addiction literature has long settled on the notion that heroin is little more than a means to deliver morphine and/or 6-MAM to the brain.
sure, right after I genetically modifie this yeast correctly 😂
@@UnrelentingFaithto most people. there are some that can definitely tell a difference ✌️💚