Thank you Daniel and Vincent for keeping this going - it's an absolutely indispensible service you provide for which I'm extremely grateful - all the way from Hong Kong.
I love to refer to y'all as my "pandemic friends". My husband and I love listening to all the microbe tv podcasts. Thx for stretching my knowledge and awareness. 💙💙💙
I wonder if the reason people think the covid tests don’t work on the new variants might actually be because so many of us are using old tests we’ve had lying around for a few years. Maybe the tests have lost effectiveness?
That was the pronunciation here in the States as well back in the 1960s. Thanks for confirming my recollection! Perhaps it’s so uncommon that people in the States haven’t heard the historic pronunciation recently…
Thank you for another update. Two of my next-door neighbors died in my hospital a couple weeks apart. The first died from pulmonary fibrosis with COVID. The second patient had no detectable virus when they got to the ER. That patient died from rapid progression of pulmonary fibrosis with no documented COVID.
Spikeopathy from injection and/or shedding? "The spike protein of SARS-CoV-2 induces inflammation and EMT of lung epithelial cells and fibroblasts through the upregulation of GADD45A" (excerpt) "... For instance, various inflammatory cytokines and chemokines have been detected in human lung epithelial cells stimulated with extracellular S protein [15]. Other studies also proved that this inflammatory reaction could be triggered by the S protein, independent of active viral infection and replication."
May I ask what region your hospital is in? I'm concerned as it sounds like what they're reporting seeing with XEC variant that's supposedly isn't in usa yet.
Vincent has often caste doubt on the usefulness of repeated 'booster' vaccination for covid. He pointed out that this gives a temporary boost to antibodies but that you probably had longer term protection against severe infection. However, the studies of booster effectiveness suggest a 40% reduction in severe infections. If the booster does only increase antibodies, then we must conclude that increased antibodies are effective in reducing the incidence of severe infection. I never understood Vincent's comments on this, perhaps he could explain.
Good question. They have a polite difference of opinion. Vincent is healthy and likely no comorbidities the average person his age is a wreck. He is not in the clinic. Just a guess but I would love to see them discuss this
He does explain on many episodes... have you ever watched his live on Wednesday nights at 8pm. He answers questions from people in chat . Has been doing it for years . There's a calendar under microbe tv calendar for his upcoming live stream or look at past videos under live .
Wish more people would watch this kind of information than all of the brain numbing stuff on RUclips or TV. I always find this to be extremely fascinating and useful
There’s a lot of stuff out there and I’m glad you guys are keeping an eye on it for us. Of course, as we all know almost all viruses have no negative impact on humans. I always remind myself that.
@@amiesparkle00 You may have expertise, but I have a feeling that those who have had Prof. Racaniello's online course on viruses have learned how ubiquitious they are.
That left me confused. Rapid tests when you first have symptoms were well correlated with PCR and that is assumed to mean it confirms you have covid and you are probably infectious. But after 5 days there was no correlation with whether you had intact virus that could infect cells in lab tests. So an early test probably tells you something (but what exactly?) whereas a later test doesn't tell you whether you are infectious. Does the early test tell you whether you are infectious? Do we know?
The rapid and rt/PCR tests detect specific portions of the virus but cannot differentiate between replication capable virus and virus debris. For the early tests a positive result is more likely to be viable virus. For latter tests the immune system has had to time to clear the virus, but debris still remains and can produce a positive result.
@37:53 the GSK RSV. I got it yesterday. Be prepared for some pretty substantial shoulder pain. Wow! I wasn’t prepared for that. At least I know my immune response was off the chart!
2 things: First, specifically defining what it means to die of or from Covid would be helpful. Secondly, knowing the age and number of comorbitities would also be helpful to know.
As regards whooping cough, in my country we pronounce it /hooping/, I've no idea where the /w/ comes from [shrug emoji] A friend of mine caught it in her 30s. Broke a rib coughing!
Yeah, growing up in the 60's there was always a few kids we knew every year coming down with whooping cough. None of them died, but it always scared their mothers.
Interesting you mention the pronunciation of whooping cough. If I recall correctly, decades ago it was pronounced “hooping” cough like a basketball hoop…. I am curious whether others over 65 ever heard that?
I think a great PSA would be pushing the importance of N95 masks. I'm puzzled as to why it is not mentioned more as a means to prevent COVID infection.
For 2023-2024, 51% of Vermonters ≥ 65 years of age had received Covid Vs. How many of the 8% of those who died because of Covid last week were ≥ 65 yo and vaccinated?
I drive eight hours a day and my anecdotal observations of other drivers during peaks in wastewater activity has been more aggressive and less attentive driving behaviors. I've been curious if there's insurance data for accidents that coincides.
If cryoglobuline level increase ,blood viscousity increase If capillary blood temperature decrease At finger level blood temperature decrease and reversibile ischemia can occur. Pulse oximetry can indicate lower false values If cryoglobuline level are high. Maybe must avoid to decrease lung temperature ?If ,,cold agglutinine,, occur also after some viral infection.
Thank you Daniel and Vincent for keeping this going - it's an absolutely indispensible service you provide for which I'm extremely grateful - all the way from Hong Kong.
And locally from NY.
I love to refer to y'all as my "pandemic friends". My husband and I love listening to all the microbe tv podcasts. Thx for stretching my knowledge and awareness. 💙💙💙
Ah! Time to listen to my friends Vincent and Daniel.
Calling them friends is presumptuous but expresses my appreciation of them!
this podcast keeps getting better, thank you
Such a clear, up to date episode on Covid protocols .. testing and treatments…. Thanks so much 🎉
Thank you all.
thank you guys!
I wonder if the reason people think the covid tests don’t work on the new variants might actually be because so many of us are using old tests we’ve had lying around for a few years. Maybe the tests have lost effectiveness?
Govt is sending free kits again
@@gferraro8353 In the US,but not in the UK.
Whooping cough: all my life its been pronounced ‘hooping cough’ in the UK. If thats wrong then i need to see an ENT specialist!!!
That was the pronunciation here in the States as well back in the 1960s. Thanks for confirming my recollection! Perhaps it’s so uncommon that people in the States haven’t heard the historic pronunciation recently…
@@JW4REnvironment Still is.
Thank you for another update. Two of my next-door neighbors died in my hospital a couple weeks apart. The first died from pulmonary fibrosis with COVID. The second patient had no detectable virus when they got to the ER. That patient died from rapid progression of pulmonary fibrosis with no documented COVID.
Spikeopathy from injection and/or shedding?
"The spike protein of SARS-CoV-2 induces inflammation and EMT of lung epithelial cells and fibroblasts through the upregulation of GADD45A"
(excerpt) "... For instance, various inflammatory cytokines and chemokines have been detected in human lung epithelial cells stimulated with extracellular S protein [15]. Other studies also proved that this inflammatory reaction could be triggered by the S protein, independent of active viral infection and replication."
May I ask what region your hospital is in? I'm concerned as it sounds like what they're reporting seeing with XEC variant that's supposedly isn't in usa yet.
@@DeniseTG13 Do you mind expanding on XEC?
@@DeniseTG13 XEC has been reported in the US; it is second in the table of subtypes.
I got my Covid shot today!
Vincent has often caste doubt on the usefulness of repeated 'booster' vaccination for covid. He pointed out that this gives a temporary boost to antibodies but that you probably had longer term protection against severe infection. However, the studies of booster effectiveness suggest a 40% reduction in severe infections. If the booster does only increase antibodies, then we must conclude that increased antibodies are effective in reducing the incidence of severe infection. I never understood Vincent's comments on this, perhaps he could explain.
Good question. They have a polite difference of opinion. Vincent is healthy and likely no comorbidities the average person his age is a wreck. He is not in the clinic. Just a guess but I would love to see them discuss this
He does explain on many episodes... have you ever watched his live on Wednesday nights at 8pm. He answers questions from people in chat . Has been doing it for years . There's a calendar under microbe tv calendar for his upcoming live stream or look at past videos under live .
But if older he does recommend, just know it wanes in a few months. 60 days. He just covered a paper @17:58 in bone marrow. Get antivirals ASAP
@@gferraro8353I love his Wednesday live streams, it's two hours of Vincent spitting science, no more, no less...
Wish more people would watch this kind of information than all of the brain numbing stuff on RUclips or TV. I always find this to be extremely fascinating and useful
Why Vermont? Why? This is a highly vaccinated and boosted state.
There’s a lot of stuff out there and I’m glad you guys are keeping an eye on it for us. Of course, as we all know almost all viruses have no negative impact on humans. I always remind myself that.
Uh I’m not so sure that is true.
@@amiesparkle00Check out Dr R’s virology course. The virome is evvvvvvvvverywhere. But only a few make humans sick.
@@amiesparkle00 You may have expertise, but I have a feeling that those who have had Prof. Racaniello's online course on viruses have learned how ubiquitious they are.
That left me confused. Rapid tests when you first have symptoms were well correlated with PCR and that is assumed to mean it confirms you have covid and you are probably infectious. But after 5 days there was no correlation with whether you had intact virus that could infect cells in lab tests. So an early test probably tells you something (but what exactly?) whereas a later test doesn't tell you whether you are infectious. Does the early test tell you whether you are infectious? Do we know?
The rapid and rt/PCR tests detect specific portions of the virus but cannot differentiate between replication capable virus and virus debris. For the early tests a positive result is more likely to be viable virus. For latter tests the immune system has had to time to clear the virus, but debris still remains and can produce a positive result.
@37:53 the GSK RSV. I got it yesterday. Be prepared for some pretty substantial shoulder pain. Wow! I wasn’t prepared for that. At least I know my immune response was off the chart!
Good thing we have vaccines for whooping cough since the last antibiotic trial was done in 1969
谢谢xie Xie, Thank you.
2 things: First, specifically defining what it means to die of or from Covid would be helpful. Secondly, knowing the age and number of comorbitities would also be helpful to know.
As regards whooping cough, in my country we pronounce it /hooping/, I've no idea where the /w/ comes from [shrug emoji]
A friend of mine caught it in her 30s. Broke a rib coughing!
Yeah, growing up in the 60's there was always a few kids we knew every year coming down with whooping cough. None of them died, but it always scared their mothers.
Interesting you mention the pronunciation of whooping cough. If I recall correctly, decades ago it was pronounced “hooping” cough like a basketball hoop…. I am curious whether others over 65 ever heard that?
@@JW4REnvironment 69 yo and US medical school graduate. We called it hooping cough.
Thanks for confirming my impression. Apparently the docs in the UK do as well.
Grew up in Wisconsin, USA, and we called it "whuppin" cough, like whuppin' ass, which it would do to you if you caught it...
i've seen the Twilight Zone enough to know the consequences of trusting the guy in the bowtie.
Now I’m wondering when you get the antibody titer, is that not b cells ?
How will we know how many people have parasite if we don't know how to look for them?
Good evening!
Why not develop monoclonal antibodies for the circulating variants?
In the UK it's known as HOOPING cough, forget the W.
People are still dying after infection in younger people without a preexisting condition. It's not just the older folks. We need the truth
How many injections? How many prior infections?
Liar@@cylon5741
I think a great PSA would be pushing the importance of N95 masks. I'm puzzled as to why it is not mentioned more as a means to prevent COVID infection.
Here in Canada we say woo-ping cough or oo-ping cough.
Hunting season? Vermont?
For 2023-2024, 51% of Vermonters ≥ 65 years of age had received Covid Vs. How many of the 8% of those who died because of Covid last week were ≥ 65 yo and vaccinated?
More likely leaf 🍁🍂 peeping tourists like crazy.
I drive eight hours a day and my anecdotal observations of other drivers during peaks in wastewater activity has been more aggressive and less attentive driving behaviors. I've been curious if there's insurance data for accidents that coincides.
If cryoglobuline level increase ,blood viscousity increase If capillary blood temperature decrease
At finger level blood temperature decrease and reversibile ischemia can occur.
Pulse oximetry can indicate lower false values If cryoglobuline level are high.
Maybe must avoid to decrease lung temperature ?If ,,cold agglutinine,, occur also after some viral infection.
W-hooping cough
Bird flu??